AU6936691A - Di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, a process for the preparation thereof, and the use thereof - Google Patents

Di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, a process for the preparation thereof, and the use thereof

Info

Publication number: AU6936691A
Authority: AU; Australia
Prior art keywords: nitroxyalkyl; amides; pyridine; preparation; dicarboxylic acids
Prior art date: 1990-01-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU69366/91A

Other versions

AU631285B2 (en

Inventor

Ekkehard Baader

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-01-16

Filing date

1991-01-15

Publication date

1991-07-18

1991-01-15 Application filed by Hoechst AG filed Critical Hoechst AG

1991-07-18 Publication of AU6936691A publication Critical patent/AU6936691A/en

1992-11-19 Application granted granted Critical

1992-11-19 Publication of AU631285B2 publication Critical patent/AU631285B2/en

2011-01-15 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Transplantation (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

AU69366/91A 1990-01-16 1991-01-15 Di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, a process for the preparation thereof, and the use thereof Ceased AU631285B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4001002		1990-01-16
DE4001002A DE4001002A1 (en)	1990-01-16	1990-01-16	N'N'-di:(nitroxyalkyl) pyridine-2,4- and -2,5-di:carboxamide derivs. - used as proline and lysine hydroxylase inhibitors for use a immuno:suppressive, fibro-suppressive and collagen biosynthesis inhibitors

Publications (2)

Publication Number	Publication Date
AU6936691A true AU6936691A (en)	1991-07-18
AU631285B2 AU631285B2 (en)	1992-11-19

Family

ID=6398117

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU69366/91A Ceased AU631285B2 (en)	1990-01-16	1991-01-15	Di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, a process for the preparation thereof, and the use thereof

Country Status (19)

Country	Link
EP (1)	EP0438795A1 (en)
JP (1)	JPH04330060A (en)
KR (1)	KR910014352A (en)
CN (1)	CN1053606A (en)
AU (1)	AU631285B2 (en)
BR (1)	BR9100159A (en)
CA (1)	CA2034206A1 (en)
CS (1)	CS7591A2 (en)
DE (1)	DE4001002A1 (en)
FI (1)	FI910177A (en)
HU (1)	HUT59102A (en)
IE (1)	IE910126A1 (en)
IL (1)	IL96941A0 (en)
MA (1)	MA22041A1 (en)
MX (1)	MX24143A (en)
NO (1)	NO910163L (en)
NZ (1)	NZ236766A (en)
PT (1)	PT96493A (en)
ZA (1)	ZA91291B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5482953A (en) *	1991-02-05	1996-01-09	Hoechst Aktiengesellschaft	2,4-and 2,5-bistetrazolylpyridines and the use thereof as pharmaceuticals

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4020570A1 (en)	1990-06-28	1992-01-02	Hoechst Ag	2,4- AND 2,5-SUBSTITUTED PYRIDINE-N-OXIDES, METHOD FOR THE PRODUCTION AND USE THEREOF
EP0533130A1 (en) *	1991-09-19	1993-03-24	Hoechst Aktiengesellschaft	2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use
EP0541042A1 (en) *	1991-11-05	1993-05-12	Hoechst Aktiengesellschaft	2,4- and 2,5-pyridine-dicarboxylic acid derivatives, process for their preparation and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK145608C (en) *	1976-04-02	1983-07-11	Chugai Pharmaceutical Co Ltd	ANALOGY PROCEDURE FOR PREPARING THE NICKETIC ACID ESTER OF N- (2-HYDROXYETHYL) NICOTINAMIDE
DE3432094A1 (en) *	1984-08-31	1986-03-06	Hoechst Ag, 6230 Frankfurt	ESTER OF PYRIDINE-2,4- AND -2,5-DICARBONIC ACID AS A MEDICINAL PRODUCT FOR INHIBITING PROLIN AND LYSINE HYDROXYLASE
DE3703959A1 (en) *	1987-02-10	1988-08-18	Hoechst Ag	PYRIDINE-2,4- AND 2,5-DICARBONIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, USE OF THE SAME AND MEDICINAL PRODUCTS BASED ON THESE COMPOUNDS

1990
- 1990-01-15 ZA ZA91291A patent/ZA91291B/en unknown
- 1990-01-16 DE DE4001002A patent/DE4001002A1/en not_active Withdrawn
- 1990-12-28 EP EP90125638A patent/EP0438795A1/en not_active Withdrawn
1991
- 1991-01-14 FI FI910177A patent/FI910177A/en unknown
- 1991-01-14 JP JP3069547A patent/JPH04330060A/en active Pending
- 1991-01-14 NZ NZ236766A patent/NZ236766A/en unknown
- 1991-01-14 KR KR1019910000412A patent/KR910014352A/en not_active Application Discontinuation
- 1991-01-14 IL IL96941A patent/IL96941A0/en unknown
- 1991-01-15 CN CN91100222A patent/CN1053606A/en active Pending
- 1991-01-15 NO NO91910163A patent/NO910163L/en unknown
- 1991-01-15 HU HU91109A patent/HUT59102A/en unknown
- 1991-01-15 MX MX2414391A patent/MX24143A/en unknown
- 1991-01-15 AU AU69366/91A patent/AU631285B2/en not_active Ceased
- 1991-01-15 CS CS9175A patent/CS7591A2/en unknown
- 1991-01-15 CA CA002034206A patent/CA2034206A1/en not_active Abandoned
- 1991-01-15 IE IE012691A patent/IE910126A1/en unknown
- 1991-01-15 BR BR919100159A patent/BR9100159A/en unknown
- 1991-01-16 PT PT96493A patent/PT96493A/en not_active Application Discontinuation
- 1991-01-16 MA MA22314A patent/MA22041A1/en unknown

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5482953A (en) *	1991-02-05	1996-01-09	Hoechst Aktiengesellschaft	2,4-and 2,5-bistetrazolylpyridines and the use thereof as pharmaceuticals
US5614537A (en) *	1991-02-05	1997-03-25	Hoechst Aktiengesellschaft	2,4-and 2,5-bistetrazolylpyridines, a process for the preparation thereof and the use thereof as pharmaceuticals

Also Published As

Publication number	Publication date
AU631285B2 (en)	1992-11-19
EP0438795A1 (en)	1991-07-31
MA22041A1 (en)	1991-10-01
FI910177A (en)	1991-07-17
FI910177A0 (en)	1991-01-14
KR910014352A (en)	1991-08-31
CN1053606A (en)	1991-08-07
IE910126A1 (en)	1991-07-17
NO910163L (en)	1991-07-17
HU910109D0 (en)	1991-08-28
PT96493A (en)	1991-10-15
NZ236766A (en)	1993-08-26
CA2034206A1 (en)	1991-07-17
HUT59102A (en)	1992-04-28
JPH04330060A (en)	1992-11-18
CS7591A2 (en)	1991-09-15
BR9100159A (en)	1991-10-22
DE4001002A1 (en)	1991-07-18
NO910163D0 (en)	1991-01-15
ZA91291B (en)	1991-09-25
MX24143A (en)	1993-05-01
IL96941A0 (en)	1992-03-29

Publication	Publication Date	Title
AU1145288A (en)	1988-08-11	Pyridine-2,4- and -2,5-dicarboxylic acid amides, processes for their preparation, the use thereof, and medicaments based on these compounds
AU3401689A (en)	1989-11-09	Detergent powders and process for preparing them
AU3149889A (en)	1989-09-21	Detergent powders and process for preparing them
ZA928495B (en)	1993-05-03	Pyridine-2,4-and -2,5-dicarboxamides and their derivatives, process for their preparation, and their use.
EP0423523A3 (en)	1992-02-19	Carboxylic acid amides, process for their preparation and their use as herbicides
HUT47249A (en)	1989-02-28	Process for producing pyridine-2,4- and -2,5-dicarboxylic acid derivatives and pharmaceuticals comprising such compounds
CS647590A3 (en)	1992-08-12	Process for preparing 6-hydroxynicotinic acid
AU7842191A (en)	1991-12-19	Process for the preparation of dialkyl pyridine-2,3,-dicarboxylates and derivatives thereof from dialakyl dichloromaleate
IL99605A0 (en)	1992-08-18	4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals
AU6936691A (en)	1991-07-18	Di(nitroxyalkyl)amides of pyridine-2,4- and -2,5-dicarboxylic acids, a process for the preparation thereof, and the use thereof
KR0156581B1 (en)	1998-11-16	1,4-benzothiazine-2-acetic acid derivatives and process for production
EP0333020A3 (en)	1991-03-20	Process for the preparation of substituted pyridines
IL107849A0 (en)	1994-04-12	A process for the preparation of 2,3,5,6- tetrachloropyridine
AU627349B2 (en)	1992-08-20	Cyclic pyridine-2,4 and -2,5-dicarboxylic acid diamides, process for their preparation and their use
ZA93210B (en)	1993-09-09	Specific 1,4-dihydropyridine-3, 5-dicarboxylic acid ester, process for its preparation and its pharmaceutical use.
AU8747391A (en)	1992-05-26	Picolinic acid derivative, production thereof, and herbicide
AU5241690A (en)	1990-10-04	Process for the preparation of pyridine-2, 3-dicarboxylic acids
AU6689590A (en)	1991-05-30	Pyridine-2,4- and 2,5-dicarboxamides, a process for the preparation thereof, and the use thereof
ZA917806B (en)	1992-05-27	4-or 5-substituted pyridine-2-carboxylic acids,a process for the preparation thereof and the use thereof as pharmaceuticals
ZA918408B (en)	1992-06-24	Process for the preparation of(3-luoropyridin-2-yloxy)phenoxypropionic acids
ZA895931B (en)	1990-04-25	An improved process for the preparation of n,n'-bis=(alkozyalkyl)-pyridine-2,4-dicarboxamides
ZA935191B (en)	1994-03-02	Specific 1,4-dihydropyridine-3,5-dicarboxylic acid ester, process for its preparation and its pharmaceutical use.
AU8847191A (en)	1992-06-11	Flavane derivative or salt thereof and novel production process
AU4587493A (en)	1994-02-14	Novel pyridonecarboxylic acid derivatives and processes for preparing the same
LTIP1739A (en)	1995-07-25	Novel 3,3'-dithiobis(propionic acids) and esthers thereof, process for their preparation and pharmaceutical preparation