AU6408586A - Novel lipoprotein-based drug-delivery systems - Google Patents
Novel lipoprotein-based drug-delivery systemsInfo
- Publication number
- AU6408586A AU6408586A AU64085/86A AU6408586A AU6408586A AU 6408586 A AU6408586 A AU 6408586A AU 64085/86 A AU64085/86 A AU 64085/86A AU 6408586 A AU6408586 A AU 6408586A AU 6408586 A AU6408586 A AU 6408586A
- Authority
- AU
- Australia
- Prior art keywords
- delivery systems
- based drug
- novel lipoprotein
- lipoprotein
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000004895 Lipoproteins Human genes 0.000 title 1
- 108090001030 Lipoproteins Proteins 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78378785A | 1985-10-03 | 1985-10-03 | |
| US783787 | 1985-10-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6408586A true AU6408586A (en) | 1987-04-24 |
Family
ID=25130391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU64085/86A Abandoned AU6408586A (en) | 1985-10-03 | 1986-10-02 | Novel lipoprotein-based drug-delivery systems |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0238645A1 (en) |
| AU (1) | AU6408586A (en) |
| WO (1) | WO1987002061A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU583402B2 (en) * | 1985-06-17 | 1989-04-27 | Oncholab A.B. | Method for the production of a macromolecular carrier loaded with a biologically active substance |
| AU596096B2 (en) * | 1985-03-11 | 1990-04-26 | Scripps Clinic And Research Foundation | A diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6522486A (en) * | 1985-10-04 | 1987-04-24 | Biotechnology Research Partners Limited | Recombinant apolipoproteins and methods |
| GB8717791D0 (en) * | 1987-07-28 | 1987-09-03 | Baralle F E | Immunoassay method |
| EP0347915A3 (en) * | 1988-06-23 | 1991-03-20 | The Rockefeller University | Method and agents for inhibiting low density lipoprotein synthesis |
| WO1992000762A1 (en) * | 1990-07-05 | 1992-01-23 | Akzo N.V. | Receptor directed-toxin conjugates |
| AU658578B2 (en) * | 1991-06-26 | 1995-04-27 | Bio-Technology General Corporation | Purification of recombinant apolipoprotein E from bacteria |
| DE69226197T2 (en) * | 1991-11-08 | 1999-02-11 | Somatogen, Inc., Boulder | HEMOGLOBINE AS A MEDICINE DELIVERY SYSTEM |
| AU682308C (en) * | 1992-04-03 | 2006-08-17 | Regents Of The University Of California, The | Self-assembling polynucleotide delivery system |
| EP0586094A1 (en) * | 1992-08-03 | 1994-03-09 | Wisconsin Alumni Research Foundation | Soluble LDL receptor and gene |
| US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US6008202A (en) | 1995-01-23 | 1999-12-28 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| US6344436B1 (en) * | 1996-01-08 | 2002-02-05 | Baylor College Of Medicine | Lipophilic peptides for macromolecule delivery |
| GB9620153D0 (en) * | 1996-09-27 | 1996-11-13 | Univ Strathclyde | Non-naturally occurring lipoprotein particle |
| WO1998024808A2 (en) * | 1996-12-06 | 1998-06-11 | THE UNITED STATES OF AMERICA represented by THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH | INHIBITION OF IgE-MEDIATED ALLERGIES BY A HUMAN IgE-DERIVED OLIGOPEPTIDE |
| US6635623B1 (en) | 1997-06-13 | 2003-10-21 | Baylor College Of Medicine | Lipoproteins as nucleic acid vectors |
| DE19745950A1 (en) * | 1997-10-17 | 1999-04-22 | Dds Drug Delivery Service Ges | Drug carrier particle for site specific drug delivery, especially to CNS |
| EP1090132A1 (en) * | 1998-06-26 | 2001-04-11 | PPL Therapeutics (Scotland) Limited | Methods for production of recombinant polypeptides |
| AU772847B2 (en) | 1998-11-12 | 2004-05-06 | Invitrogen Corporation | Transfection reagents |
| AU2001257613A1 (en) * | 2000-04-23 | 2001-11-12 | Arizeke Pharmaceuticals, Inc. | Compositions comprising carriers and transportable complexes |
| AU2003302676A1 (en) | 2002-12-03 | 2004-06-23 | Blanchette Rockefeller Neurosciences Institute | Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier |
| US7803400B2 (en) | 2002-12-03 | 2010-09-28 | Blanchette Rockefeller Neurosciences Institute | Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier |
| WO2004069207A2 (en) * | 2003-02-04 | 2004-08-19 | University Of Connecticut Health Center | Immunogenic cd91 ligand-antigenic molecule complexes and fusion proteins |
| CA2534708A1 (en) * | 2003-08-05 | 2005-02-17 | Wisconsin Alumni Research Foundation | Targeted carrier fusions for delivery of chemotherapeutic agents |
| US8252338B2 (en) * | 2005-11-10 | 2012-08-28 | The Regents Of The University Of California | Synthetic LDL as targeted drug delivery vehicle |
| JP5685529B2 (en) * | 2008-06-13 | 2015-03-18 | プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダProyecto De Biomedicina Cima, S.L. | Complexes for the administration of compounds having biological activity |
| WO2011044545A2 (en) * | 2009-10-09 | 2011-04-14 | Sigalov Alexander B | Methods and compositions for targeted imaging |
| US12419839B2 (en) | 2009-10-09 | 2025-09-23 | Signablok, Inc. | Methods and compositions for targeted delivery of protein fragments |
| CN102753574B (en) * | 2009-12-11 | 2015-05-20 | 西马生物医学计划公司 | Novel conjugates and compositions for immunotherapy and antineoplastic treatment |
| EP3169310A1 (en) | 2014-07-15 | 2017-05-24 | Life Technologies Corporation | Compositions with lipid aggregates and methods for efficient delivery of molecules to cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2862449D1 (en) * | 1977-08-22 | 1984-11-22 | Nat Res Dev | Macromolecular covalent conjugates, methods for preparing and pharmaceutical compositions containing them |
| US4411994A (en) * | 1978-06-08 | 1983-10-25 | The President And Fellows Of Harvard College | Protein synthesis |
| US4429008B1 (en) * | 1981-12-10 | 1995-05-16 | Univ California | Thiol reactive liposomes |
-
1986
- 1986-10-02 AU AU64085/86A patent/AU6408586A/en not_active Abandoned
- 1986-10-02 EP EP86906200A patent/EP0238645A1/en not_active Withdrawn
- 1986-10-02 WO PCT/US1986/002074 patent/WO1987002061A1/en not_active Ceased
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU596096B2 (en) * | 1985-03-11 | 1990-04-26 | Scripps Clinic And Research Foundation | A diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins |
| AU583402B2 (en) * | 1985-06-17 | 1989-04-27 | Oncholab A.B. | Method for the production of a macromolecular carrier loaded with a biologically active substance |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0238645A1 (en) | 1987-09-30 |
| WO1987002061A1 (en) | 1987-04-09 |
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