US6811779B2
(en)
*
|
1994-02-10 |
2004-11-02 |
Imclone Systems Incorporated |
Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy
|
US20030108545A1
(en)
*
|
1994-02-10 |
2003-06-12 |
Patricia Rockwell |
Combination methods of inhibiting tumor growth with a vascular endothelial growth factor receptor antagonist
|
US7122636B1
(en)
|
1997-02-21 |
2006-10-17 |
Genentech, Inc. |
Antibody fragment-polymer conjugates and uses of same
|
EP2343085B1
(en)
*
|
1997-03-10 |
2014-12-10 |
The Regents of The University of California |
Antibody against prostate stem cell antigen (PSCA)
|
US20020173629A1
(en)
|
1997-05-05 |
2002-11-21 |
Aya Jakobovits |
Human monoclonal antibodies to epidermal growth factor receptor
|
US6235883B1
(en)
*
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
DE69841549D1
(en)
*
|
1997-05-14 |
2010-04-22 |
Sloan Kettering Inst Cancer |
PROCESS AND PREPARATIONS FOR DESTRUCTION OF CERTAIN PROTEINS
|
US6417168B1
(en)
|
1998-03-04 |
2002-07-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
US6706721B1
(en)
|
1998-04-29 |
2004-03-16 |
Osi Pharmaceuticals, Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
BR9910511A
(en)
*
|
1998-05-15 |
2001-11-20 |
Imclone Systems Inc |
Treatment of human tumors with radiation and growth factor receptor tyrosine kinase inhibitors
|
EP1154782A4
(en)
*
|
1999-02-24 |
2002-09-25 |
Uab Research Foundation |
TAXANE DERIVATIVES FOR TARGETED CANCER THERAPY
|
WO2000069459A1
(en)
*
|
1999-05-14 |
2000-11-23 |
Imclone Systems Incorporated |
Treatment of refractory human tumors with epidermal growth factor receptor antagonists
|
DE60042648D1
(en)
|
1999-06-25 |
2009-09-10 |
Genentech Inc |
HUMANIZED ANTI-ERBB2 ANTIBODIES AND TREATMENT WITH ANTI-ERBB2 ANTIBODIES
|
WO2001015730A1
(en)
|
1999-08-27 |
2001-03-08 |
Genentech, Inc. |
DOSAGES FOR TREATMENT WITH ANTI-ErbB2 ANTIBODIES
|
US7087613B2
(en)
|
1999-11-11 |
2006-08-08 |
Osi Pharmaceuticals, Inc. |
Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
UA74803C2
(en)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
A stable polymorph of n-(3-ethynylphenyl)-6,7-bis(2-methoxyetoxy)-4-quinazolinamine hydrochloride, a method for producing thereof (variants) and pharmaceutical use
|
AU2001247616B2
(en)
|
2000-04-11 |
2007-06-14 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
KR20080038458A
(en)
|
2000-05-19 |
2008-05-06 |
제넨테크, 인크. |
Genetic detection assays to improve the likelihood of an effective response to cancer therapy with ERW antagonists
|
AU2001295002B2
(en)
*
|
2000-08-09 |
2007-05-31 |
Imclone Systems Incorporated |
Treatment of hyperproliferative diseases with epidermal growth factor receptor antagonists
|
PT1361893E
(en)
*
|
2001-02-19 |
2013-01-24 |
Merck Patent Gmbh |
Modified anti-egfr antibodies with reduced immunogenicity
|
JP2004528851A
(en)
*
|
2001-05-07 |
2004-09-24 |
ハイブリドン・インコーポレイテッド |
Epidermal growth factor receptor antisense oligonucleotides
|
US20110313230A1
(en)
|
2001-05-11 |
2011-12-22 |
Terrance Grant Johns |
Specific binding proteins and uses thereof
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
WO2002092771A2
(en)
|
2001-05-11 |
2002-11-21 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
DE10133394A1
(en)
*
|
2001-07-13 |
2003-01-30 |
Merck Patent Gmbh |
Liquid formulation containing cetuximab
|
US7241444B2
(en)
|
2002-01-18 |
2007-07-10 |
Pierre Fabre Medicament |
Anti-IGF-IR antibodies and uses thereof
|
DE60312639T2
(en)
*
|
2002-01-18 |
2007-11-29 |
Pierre Fabre Médicament |
ANTIBODIES TO IGF-IR AND ITS USES
|
DE60325334D1
(en)
|
2002-02-05 |
2009-01-29 |
Genentech Inc |
PROTEIN PURIFICATION
|
US7657380B2
(en)
|
2003-12-04 |
2010-02-02 |
Xencor, Inc. |
Methods of generating variant antibodies with increased host string content
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
EP1499352A4
(en)
*
|
2002-04-12 |
2006-10-11 |
Medimmune Inc |
RECOMBINANT ANTI-INTERLEUKIN-9 ANTIBODIES
|
HUE025101T2
(en)
|
2002-04-26 |
2016-02-29 |
Genentech Inc |
Non-affinity purification of proteins
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
PL214010B1
(en)
|
2002-07-15 |
2013-06-28 |
Genentech Inc |
METHODS FOR IDENTIFYING TUMORS THAT ARE RESPONSIVE TO TREATMENT WITH ANTI-ErbB2 ANTIBODIES
|
DK1553975T3
(en)
|
2002-09-27 |
2012-05-07 |
Xencor Inc |
Optimized Fc variants and methods for their generation.
|
EP3299393A1
(en)
*
|
2002-11-08 |
2018-03-28 |
Ablynx N.V. |
Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
US20060034845A1
(en)
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
CA2516056C
(en)
|
2003-01-06 |
2012-05-29 |
Angiochem Inc. |
Aprotinin and analogs as carriers across the blood-brain barrier
|
EP2264151B1
(en)
|
2003-01-22 |
2016-04-20 |
Roche Glycart AG |
Fusion constructs and use of same to produce antibodies with increased FC receptor binding affinity and effector function
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
WO2004093807A2
(en)
|
2003-04-22 |
2004-11-04 |
Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. |
Somatostatin vectors
|
ES2786568T3
(en)
|
2003-07-28 |
2020-10-13 |
Genentech Inc |
Reduction of protein A leaching during protein A affinity chromatography
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
AU2004316290C1
(en)
|
2003-11-06 |
2012-02-02 |
Seagen Inc. |
Monomethylvaline compounds capable of conjugation to ligands
|
DE10355904A1
(en)
*
|
2003-11-29 |
2005-06-30 |
Merck Patent Gmbh |
Solid forms of anti-EGFR antibodies
|
EP1701979A2
(en)
*
|
2003-12-03 |
2006-09-20 |
Xencor, Inc. |
Optimized antibodies that target the epidermal growth factor receptor
|
JP4969440B2
(en)
|
2004-04-08 |
2012-07-04 |
デビッド, ビー. エイガス, |
ErbB antagonist for the treatment of pain
|
EP2286844A3
(en)
|
2004-06-01 |
2012-08-22 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
DK2471813T3
(en)
|
2004-07-15 |
2015-03-02 |
Xencor Inc |
Optimized Fc variants
|
US7662926B2
(en)
|
2004-09-02 |
2010-02-16 |
Genentech, Inc. |
Anti-Fc-gamma receptor antibodies, bispecific variants and uses therefor
|
US7655229B2
(en)
|
2004-09-02 |
2010-02-02 |
Chan Andrew C |
Anti-FC-gamma RIIB receptor antibody and uses therefor
|
ES2669510T3
(en)
|
2004-09-23 |
2018-05-28 |
Genentech, Inc. |
Antibodies and conjugates engineered with cysteine
|
JO3000B1
(en)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
Antibody Formulations.
|
US7939267B2
(en)
|
2004-11-04 |
2011-05-10 |
Laboratory Corporation Of America Holdings |
Detection of activation of endothelial cells as surrogate marker for angiogenesis
|
EP2845865A1
(en)
|
2004-11-12 |
2015-03-11 |
Xencor Inc. |
Fc variants with altered binding to FcRn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US7598043B2
(en)
|
2004-11-19 |
2009-10-06 |
Cornell Research Foundation, Inc. |
Use of vascular endothelial growth factor receptor 1+ cells in treating and monitoring cancer and in screening for chemotherapeutics
|
KR20150083139A
(en)
|
2005-01-21 |
2015-07-16 |
제넨테크, 인크. |
Fixed dosing of her antibodies
|
JP5475234B2
(en)
|
2005-01-21 |
2014-04-16 |
アステックス・セラピューティクス・リミテッド |
Pharmaceutical compounds
|
BRPI0520032A2
(en)
|
2005-02-18 |
2009-04-14 |
Angiochem Inc |
molecules to carry a compound through the blood brain barrier
|
RS53128B
(en)
|
2005-02-23 |
2014-06-30 |
Genentech Inc. |
Extending time to disease progression or survival in ovarian cancer patients using pertuzumab
|
AR053272A1
(en)
|
2005-05-11 |
2007-04-25 |
Hoffmann La Roche |
DETERMINATION OF RESPONSIVES TO CHEMOTHERAPY
|
EP2471555A3
(en)
|
2005-07-15 |
2012-10-17 |
Angiochem Inc. |
Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
|
US9580506B2
(en)
|
2005-07-21 |
2017-02-28 |
Genmab A/S |
Potency assays for antibody drug substance binding to an Fc receptor
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
EP2500356A3
(en)
|
2005-08-19 |
2012-10-24 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
CA2618482C
(en)
|
2005-08-19 |
2014-10-07 |
Abbott Laboratories |
Dual variable domain immunoglobin and uses thereof
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
CA2629095A1
(en)
|
2005-11-12 |
2007-05-24 |
Eli Lily And Company |
Anti-egfr antibodies
|
KR101353706B1
(en)
|
2006-02-03 |
2014-02-18 |
유니버시티 오브 워싱톤 |
Igf-ir antagonists as adjuvants for treatment of prostate cancer
|
AR060635A1
(en)
|
2006-04-27 |
2008-07-02 |
Banyu Pharma Co Ltd |
DERIVATIVES OF 1,2-DIHIDRO-3H-PIRAZOLO [3,4-D] PIRIMIDIN-3-ONA, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM AND THEIR USE IN THE TREATMENT OF CANCER
|
FR2902799B1
(en)
|
2006-06-27 |
2012-10-26 |
Millipore Corp |
METHOD AND UNIT FOR PREPARING A SAMPLE FOR THE MICROBIOLOGICAL ANALYSIS OF A LIQUID
|
JP2008081492A
(en)
|
2006-08-31 |
2008-04-10 |
Banyu Pharmaceut Co Ltd |
Novel aminopyridine derivatives having selective inhibition of Aurora A
|
ES2530438T3
(en)
|
2006-09-12 |
2015-03-02 |
Genentech Inc |
Procedures and compositions for the diagnosis and treatment of lung cancer using the KIT or KDR gene as a genetic marker
|
US8883790B2
(en)
|
2006-10-12 |
2014-11-11 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
EP2073803B1
(en)
|
2006-10-12 |
2018-09-19 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US7820159B2
(en)
*
|
2006-10-31 |
2010-10-26 |
Instiute of Virology of the Slovak Academy of Sciences |
MN/CA IX and EGFR pathway inhibition
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
US8163886B2
(en)
|
2006-12-21 |
2012-04-24 |
Emd Millipore Corporation |
Purification of proteins
|
US7977336B2
(en)
|
2006-12-28 |
2011-07-12 |
Banyu Pharmaceutical Co. Ltd |
Aminopyrimidine derivatives as PLK1 inhibitors
|
EP2123676A4
(en)
*
|
2007-01-05 |
2011-01-05 |
Univ Tokyo |
DIAGNOSIS AND TREATMENT OF CANCERS USING ANTI-PRG-3 ANTIBODY
|
ES2374330T3
(en)
|
2007-01-22 |
2012-02-15 |
Genentech, Inc. |
PRECIPITATION WITH POLYELECTROLYTE AND PURIFICATION OF ANTIBODIES.
|
MX338185B
(en)
|
2007-01-25 |
2016-04-05 |
Dana Farber Cancer Inst Inc |
Use of anti-egfr antibodies in treatment of egfr mutant mediated disease.
|
US8450068B2
(en)
*
|
2007-02-16 |
2013-05-28 |
University Of Virginia Patent Foundation |
IgE antibodies to chimeric or humanized IgG therapeutic monoclonal antibodies as a screening test for anaphylaxis
|
MX2009008909A
(en)
|
2007-03-01 |
2009-08-28 |
Symphogen As |
Recombinant anti-epidermal growth factor receptor antibody compositions.
|
AU2008223069B2
(en)
|
2007-03-02 |
2012-12-13 |
F. Hoffmann-La Roche Ag |
Predicting response to a HER dimerisation inhibitor based on low HER3 expression
|
CA2680854C
(en)
|
2007-03-15 |
2017-02-14 |
Ludwig Institute For Cancer Research |
Treatment method using egfr antibodies and src inhibitors and related formulations
|
US9365634B2
(en)
|
2007-05-29 |
2016-06-14 |
Angiochem Inc. |
Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
|
EP2592156B1
(en)
|
2007-06-08 |
2016-04-20 |
Genentech, Inc. |
Gene expression markers of tumor resistance to HER2 inhibitor treatment
|
DK3597659T5
(en)
|
2007-07-09 |
2024-09-02 |
Genentech Inc |
Prevention of disulfide bond reduction during recombinant production of polypeptides
|
MX2010001757A
(en)
|
2007-08-14 |
2010-09-14 |
Ludwig Inst Cancer Res |
Monoclonal antibody 175 targeting the egf receptor and derivatives and uses thereof.
|
EP2044949A1
(en)
*
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
AU2008315048A1
(en)
|
2007-10-23 |
2009-04-30 |
Msd K.K. |
Pyridone-substituted-dihydropyrazolopyrimidinone derivative
|
KR20150008503A
(en)
|
2007-10-30 |
2015-01-22 |
제넨테크, 인크. |
Antibody purification by cation exchange chromatography
|
RU2480211C2
(en)
|
2007-11-12 |
2013-04-27 |
Байпар Сайенсиз, Инк. |
Method of treating breast cancer with compound of 4-iodine-3-nitrobenzamine in combination with anticancer agents
|
CN105418762B
(en)
|
2007-12-26 |
2019-11-05 |
Xencor公司 |
With the Fc variant of FcRn Binding change
|
US8454960B2
(en)
*
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
TWI472339B
(en)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
Composition comprising antibody that binds to domain ii of her2 and acidic variants thereof
|
BRPI0910482A2
(en)
|
2008-04-29 |
2019-09-24 |
Abbott Lab |
double variable domain immunoglobins and their uses
|
SG191639A1
(en)
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
TW201006485A
(en)
|
2008-06-03 |
2010-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
WO2009151514A1
(en)
|
2008-06-11 |
2009-12-17 |
Millipore Corporation |
Stirred tank bioreactor
|
AU2009268585C1
(en)
|
2008-07-08 |
2014-10-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
RS59232B1
(en)
|
2008-08-14 |
2019-10-31 |
Genentech Inc |
Methods for removing a contaminant using indigenous protein displacement ion exchange membrane chromatography
|
US8663640B2
(en)
|
2008-08-29 |
2014-03-04 |
Symphogen A/S |
Methods using recombinant anti-epidermal growth factor receptor antibody compositions
|
CA2734275A1
(en)
|
2008-09-10 |
2010-03-18 |
Genentech, Inc. |
Compositions and methods for the prevention of oxidative degradation of proteins
|
EP3524620A1
(en)
|
2008-10-14 |
2019-08-14 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
WO2010043047A1
(en)
|
2008-10-15 |
2010-04-22 |
Angiochem Inc. |
Conjugates of glp-1 agonists and uses thereof
|
WO2010063122A1
(en)
|
2008-12-05 |
2010-06-10 |
Angiochem Inc. |
Conjugates of neurotensin or neurotensin analogs and uses thereof
|
SG171764A1
(en)
|
2008-12-16 |
2011-07-28 |
Millipore Corp |
Purification of proteins
|
JP2012511929A
(en)
|
2008-12-16 |
2012-05-31 |
イー・エム・デイー・ミリポア・コーポレイシヨン |
Stirred tank reactor and method
|
JP2012518598A
(en)
|
2009-02-25 |
2012-08-16 |
Msd株式会社 |
Pyrimidopyrimidoindazole derivatives
|
EP2400992B1
(en)
|
2009-02-27 |
2015-07-22 |
Genentech, Inc. |
Methods and compositions for protein labelling
|
JP5836807B2
(en)
|
2009-03-05 |
2015-12-24 |
アッヴィ・インコーポレイテッド |
IL-17 binding protein
|
EP2403339B1
(en)
|
2009-03-06 |
2017-01-18 |
Merck Sharp & Dohme Corp. |
Combination cancer therapy with an akt inhibitor and other anticancer agents
|
PE20120539A1
(en)
|
2009-03-20 |
2012-05-12 |
Genentech Inc |
ANTI-HER BIESPECIFIC ANTIBODIES
|
AU2010233995A1
(en)
*
|
2009-04-07 |
2011-09-08 |
Roche Glycart Ag |
Bispecific anti-ErbB-2/anti-c-Met antibodies
|
US9173891B2
(en)
|
2009-04-20 |
2015-11-03 |
Angiochem, Inc. |
Treatment of ovarian cancer using an anticancer agent conjugated to an angiopep-2 analog
|
EP2443234B1
(en)
|
2009-06-15 |
2018-08-15 |
Icon Genetics GmbH |
Nicotiana benthamiana plants deficient in xylosyltransferase activity
|
IN2012DN00248A
(en)
|
2009-07-02 |
2015-05-01 |
Angiochem Inc |
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
MX2012001742A
(en)
|
2009-08-11 |
2012-03-21 |
Genentech Inc |
Production of proteins in glutamine-free cell culture media.
|
US9428548B2
(en)
|
2009-09-01 |
2016-08-30 |
Genentech, Inc. |
Enhanced protein purification through a modified protein A elution
|
US8586714B2
(en)
|
2009-09-01 |
2013-11-19 |
Abbvie, Inc. |
Dual variable domain immunoglobulins and uses thereof
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
ES2354922B1
(en)
|
2009-09-02 |
2012-02-07 |
Fundacion Institut De Recerca De L'hospital Universitari Vall D'hebron |
MARKERS FOR THE SELECTION OF PERSONALIZED THERAPIES FOR THE TREATMENT OF THE C�? NCER.
|
AR078161A1
(en)
|
2009-09-11 |
2011-10-19 |
Hoffmann La Roche |
VERY CONCENTRATED PHARMACEUTICAL FORMULATIONS OF AN ANTIBODY ANTI CD20. USE OF THE FORMULATION. TREATMENT METHOD
|
US20110076232A1
(en)
|
2009-09-29 |
2011-03-31 |
Ludwig Institute For Cancer Research |
Specific binding proteins and uses thereof
|
PE20121531A1
(en)
|
2009-10-15 |
2012-12-22 |
Abbott Lab |
IMMUNOGLOBULINS WITH DUAL VARIABLE DOMAIN
|
UY32979A
(en)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
IMMUNOGLOBULINS WITH DUAL VARIABLE DOMAIN AND USES OF THE SAME
|
CN107337734A
(en)
|
2009-12-04 |
2017-11-10 |
弗·哈夫曼-拉罗切有限公司 |
Multi-specificity antibody, antibody analog, composition and method
|
JP2013517220A
(en)
|
2010-01-12 |
2013-05-16 |
エフ.ホフマン−ラ ロシュ アーゲー |
Tricyclic heterocyclic compounds, compositions thereof, and methods of use
|
US20120309056A1
(en)
|
2010-02-04 |
2012-12-06 |
Leon Arnaud |
Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
AU2011218125A1
(en)
|
2010-02-18 |
2012-07-19 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
WO2011103389A1
(en)
|
2010-02-19 |
2011-08-25 |
Cornell University |
Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases
|
AU2011222012C1
(en)
|
2010-03-02 |
2015-02-26 |
Kyowa Kirin Co., Ltd. |
Modified antibody composition
|
KR20130001272A
(en)
|
2010-03-17 |
2013-01-03 |
에프. 호프만-라 로슈 아게 |
Imidazopyridine compounds, compositions and methods of use
|
KR20180000342A
(en)
|
2010-03-22 |
2018-01-02 |
제넨테크, 인크. |
Compositions and methods useful for stabilizing protein-containing formulations
|
EP2554669B1
(en)
|
2010-03-26 |
2018-09-19 |
Kyowa Hakko Kirin Co., Ltd. |
Novel antibody having modification site introduced therein, and antibody fragment
|
EP2552957A4
(en)
|
2010-03-29 |
2013-11-20 |
Zymeworks Inc |
ANTIBODIES HAVING ENHANCED OR DELETED EFFECTIVE FUNCTION
|
ES2993140T3
(en)
|
2010-04-02 |
2024-12-23 |
Amunix Pharmaceuticals Inc |
Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
|
WO2011130654A1
(en)
|
2010-04-16 |
2011-10-20 |
Genentech, Inc. |
Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
BR112012027828A2
(en)
|
2010-05-03 |
2016-08-09 |
Genentech Inc |
matter composition, article of manufacture and method of reducing the viscosity of a protein containing formulation and preparing an aqueous protein containing formulation
|
KR101848225B1
(en)
|
2010-05-14 |
2018-04-12 |
애브비 인코포레이티드 |
Il-1 binding proteins
|
SG10201804385YA
(en)
|
2010-05-17 |
2018-06-28 |
Emd Millipore Corp |
Stimulus responsive polymers for the purification of biomolecules
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
WO2011150241A2
(en)
|
2010-05-28 |
2011-12-01 |
Genentech, Inc. |
Decreasing lactate level and increasing polypeptide production by downregulating the expression of lactate dehydrogenase and pyruvate dehydrogenase kinase
|
KR102058307B1
(en)
|
2010-06-24 |
2019-12-20 |
제넨테크, 인크. |
Compositions and methods containing alkylgycosides for stabilizing protein-containing formulations
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
UY33492A
(en)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
IMMUNOGLOBULINS WITH DUAL VARIABLE DOMAIN AND USES OF THE SAME
|
CN105585630B
(en)
|
2010-07-29 |
2020-09-15 |
Xencor公司 |
Antibodies with modified isoelectric points
|
JP2013537415A
(en)
|
2010-08-03 |
2013-10-03 |
アッヴィ・インコーポレイテッド |
Dual variable domain immunoglobulins and uses thereof
|
CA2805984C
(en)
|
2010-08-10 |
2021-05-25 |
Glycotope Gmbh |
Antibodies, functional fragments and derivatives having a sialylated fab region
|
US9051370B2
(en)
*
|
2010-08-10 |
2015-06-09 |
Glycotope Gmbh |
Humanized EGFR antibodies
|
BR112013003279A2
(en)
|
2010-08-13 |
2016-06-14 |
Genentech In |
"Methods for treating a disease, method for neutralizing or blocking il-1ß and / or il-18 activity, antibody, uses of an antibody and uses of a monoclonal antibody"
|
PH12013500337A1
(en)
|
2010-08-26 |
2017-08-23 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
SG187886A1
(en)
|
2010-08-31 |
2013-04-30 |
Genentech Inc |
Biomarkers and methods of treatment
|
WO2012030512A1
(en)
|
2010-09-03 |
2012-03-08 |
Percivia Llc. |
Flow-through protein purification process
|
CA2812087A1
(en)
|
2010-09-15 |
2012-03-22 |
F. Hoffmann-La Roche Ag |
Azabenzothiazole compounds, compositions and methods of use
|
US8962804B2
(en)
|
2010-10-08 |
2015-02-24 |
City Of Hope |
Meditopes and meditope-binding antibodies and uses thereof
|
EP2624868B1
(en)
*
|
2010-10-08 |
2018-09-26 |
City of Hope |
A monoclonal antibody framework binding interface for meditopes, meditope delivery systems and methods for their use
|
US9309322B2
(en)
|
2010-11-12 |
2016-04-12 |
Scott & White Healthcare (Swh) |
Antibodies to tumor endothelial marker 8
|
WO2012066061A1
(en)
|
2010-11-19 |
2012-05-24 |
F. Hoffmann-La Roche Ag |
Pyrazolopyridines and pyrazolopyridines and their use as tyk2 inhibitors
|
TW201249865A
(en)
|
2010-12-21 |
2012-12-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
WO2012085176A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Tricyclic pyrazinone compounds, compositions and methods of use thereof as janus kinase inhibitors
|
WO2012091023A1
(en)
|
2010-12-27 |
2012-07-05 |
協和発酵キリン株式会社 |
Method for preparing aqueous solution containing culture medium and chelating agent
|
WO2012095514A1
(en)
|
2011-01-14 |
2012-07-19 |
Vivalis |
Recombinant protein production system
|
WO2012100346A1
(en)
*
|
2011-01-24 |
2012-08-02 |
Ym Biosciences Inc. |
Antibodies selective for cells presenting egfr at high density
|
MX358752B
(en)
|
2011-03-25 |
2018-08-31 |
Glenmark Pharmaceuticals Sa |
Hetero-dimeric immunoglobulins.
|
CN106432506A
(en)
|
2011-05-24 |
2017-02-22 |
泽恩格尼亚股份有限公司 |
Multivalent and monovalent multispecific complexes and their uses
|
US20150004252A1
(en)
|
2011-06-20 |
2015-01-01 |
Traslational Cancer Drugs Pharma, S.L |
Method for predicting the clinical response to chemotherapy in a subject with cancer
|
WO2019071023A1
(en)
|
2017-10-04 |
2019-04-11 |
Yale University |
Compositions and methods for making selenocysteine containing polypeptides
|
WO2013009868A1
(en)
|
2011-07-11 |
2013-01-17 |
Yale University |
Compositions and methods for making selenocysteine containing polypeptides
|
WO2013007768A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
|
WO2013007765A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Fused tricyclic compounds for use as inhibitors of janus kinases
|
EP2551348B1
(en)
|
2011-07-29 |
2014-09-24 |
Icon Genetics GmbH |
Production of galactosylated N-glycans in plants
|
WO2013022855A1
(en)
|
2011-08-05 |
2013-02-14 |
Xencor, Inc. |
Antibodies with modified isoelectric points and immunofiltering
|
BR112014003237A2
(en)
|
2011-08-12 |
2017-04-25 |
Hoffmann La Roche |
indazole compounds, compositions and methods of use
|
KR20140057326A
(en)
|
2011-08-17 |
2014-05-12 |
제넨테크, 인크. |
Neuregulin antibodies and uses thereof
|
CN107586340B
(en)
|
2011-08-23 |
2022-01-21 |
罗切格利卡特公司 |
Bispecific antibodies specific for T cell activating antigens and tumor antigens and methods of use
|
CN103827115A
(en)
|
2011-09-20 |
2014-05-28 |
弗·哈夫曼-拉罗切有限公司 |
Imidazopyridine compounds, compositions and methods of use
|
AU2012320847B2
(en)
|
2011-10-04 |
2018-03-08 |
Icon Genetics Gmbh |
Nicotiana benthamiana plants deficient in fucosyltransferase activity
|
AU2012323287B2
(en)
|
2011-10-10 |
2018-02-01 |
Xencor, Inc. |
A method for purifying antibodies
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
SG11201401791WA
(en)
|
2011-10-24 |
2014-08-28 |
Abbvie Inc |
Immunobinders directed against sclerostin
|
CA2857114A1
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
RU2648999C2
(en)
|
2011-12-22 |
2018-03-29 |
Дженентек, Инк. |
Methods of the proteins downstream purification efficiency increasing with the use of membrane ion exchange chromatography
|
AR089529A1
(en)
|
2011-12-30 |
2014-08-27 |
Abbvie Inc |
UNION PROTEINS SPECIFIC DUALS DIRECTED AGAINST IL-13 AND / OR IL-17
|
US9428553B2
(en)
|
2012-02-10 |
2016-08-30 |
City Of Hope |
Meditopes and meditope-binding antibodies and uses thereof
|
US20140170159A9
(en)
|
2012-03-08 |
2014-06-19 |
Ge Wei |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
WO2013148249A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Improved harvest operations for recombinant proteins
|
AU2013240261A1
(en)
|
2012-03-27 |
2014-09-18 |
Genentech, Inc. |
Diagnosis and treatments relating to HER3 inhibitors
|
SI2849723T1
(en)
|
2012-05-18 |
2018-09-28 |
Genentech, Inc. |
High-concentration monoclonal antibody formulations
|
US10233503B2
(en)
|
2012-05-24 |
2019-03-19 |
Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) |
Method for the identification of the origin of a cancer of unknown primary origin by methylation analysis
|
DK2859017T3
(en)
|
2012-06-08 |
2019-05-13 |
Sutro Biopharma Inc |
ANTIBODIES INCLUDING PLACE-SPECIFIC NON-NATURAL AMINO ACID, PROCEDURE FOR MANUFACTURING ITS AND METHODS OF USE THEREOF
|
JP6103832B2
(en)
|
2012-06-25 |
2017-03-29 |
Hoya株式会社 |
EGFR binding peptide
|
UY34905A
(en)
|
2012-07-12 |
2014-01-31 |
Abbvie Inc |
IL-1 UNION PROTEINS
|
EP4074728A1
(en)
|
2012-08-31 |
2022-10-19 |
Sutro Biopharma, Inc. |
Modified peptides comprising an azido group
|
RU2015117393A
(en)
|
2012-10-08 |
2016-12-10 |
Роше Гликарт Аг |
Deprived fc antibodies containing two Fab fragments, and methods for their use
|
EP2911692B1
(en)
|
2012-10-26 |
2019-08-21 |
The University of Queensland |
Use of endocytosis inhibitors and antibodies for cancer therapy
|
TW201838651A
(en)
|
2012-11-01 |
2018-11-01 |
美商艾伯維有限公司 |
Stable dual variable domain immunoglobulin protein formulations
|
MX2015005593A
(en)
|
2012-11-01 |
2016-02-05 |
Abbvie Inc |
Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof.
|
EP2934602B1
(en)
|
2012-12-19 |
2019-02-27 |
Genentech, Inc. |
Methods and compositions for radiohalogen protein labeling
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
KR102391731B1
(en)
|
2013-01-14 |
2022-04-27 |
젠코어 인코포레이티드 |
Novel heterodimeric proteins
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9738722B2
(en)
|
2013-01-15 |
2017-08-22 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
WO2014122582A1
(en)
|
2013-02-05 |
2014-08-14 |
Nestec S.A. |
Drug selection for non-small cell lung cancer therapy
|
WO2014128235A1
(en)
|
2013-02-22 |
2014-08-28 |
F. Hoffmann-La Roche Ag |
Methods of treating cancer and preventing drug resistance
|
KR20230004901A
(en)
|
2013-02-26 |
2023-01-06 |
로슈 글리카트 아게 |
Bispecific t cell activating antigen binding molecules
|
CA2896370A1
(en)
|
2013-02-26 |
2014-09-04 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
CN105246511A
(en)
|
2013-03-06 |
2016-01-13 |
豪夫迈·罗氏有限公司 |
Methods of treating and preventing cancer drug resistance
|
RU2015143517A
(en)
|
2013-03-13 |
2017-04-19 |
Дженентек, Инк. |
Pyrazole-containing compounds and their use
|
WO2014153030A2
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
CN105246508A
(en)
|
2013-03-14 |
2016-01-13 |
基因泰克公司 |
Combinations of MEK inhibitor compounds and HER3/EGFR inhibitor compounds and methods of use
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
CN105324396A
(en)
|
2013-03-15 |
2016-02-10 |
艾伯维公司 |
Dual specific binding proteins directed against il-1 beta and il-17
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
RU2015143437A
(en)
|
2013-03-15 |
2017-04-27 |
Дженентек, Инк. |
METHODS FOR TREATING CANCER AND PREVENTING RESISTANCE TO MEDICINES FOR TREATING CANCER
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
AU2014232416B2
(en)
|
2013-03-15 |
2017-09-28 |
Xencor, Inc. |
Modulation of T Cells with Bispecific Antibodies and FC Fusions
|
CA2904528C
(en)
|
2013-03-15 |
2021-01-19 |
Abbvie Biotherapeutics Inc. |
Fc variants
|
ES2658039T3
(en)
|
2013-07-10 |
2018-03-08 |
Sutro Biopharma, Inc. |
Antibodies comprising multiple site-specific non-natural amino acid residues, methods for their preparation and methods of use
|
WO2015035044A2
(en)
|
2013-09-04 |
2015-03-12 |
Abbvie Biotherapeutics Inc. |
Fc VARIANTS WITH IMPROVED ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
|
RU2016112568A
(en)
|
2013-09-05 |
2017-10-06 |
Дженентек, Инк. |
ANTIPROLIFERATIVE COMPOUNDS
|
SG11201510740YA
(en)
|
2013-09-17 |
2016-01-28 |
Obi Pharma Inc |
Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment
|
WO2015049325A1
(en)
|
2013-10-03 |
2015-04-09 |
F. Hoffmann-La Roche Ag |
Therapeutic inhibitors of cdk8 and uses thereof
|
EP3055298B1
(en)
|
2013-10-11 |
2020-04-29 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
BR112016008477A2
(en)
|
2013-10-18 |
2017-10-03 |
Genentech Inc |
BODIES, NUCLEIC ACID, HOST CELL, METHOD OF PRODUCING AN ANTIBODY, IMMUNOCONJUGATE, PHARMACEUTICAL FORMULATION AND USES OF THE ANTIBODY
|
SG10201909806SA
(en)
|
2013-11-04 |
2019-11-28 |
Glenmark Pharmaceuticals Sa |
Production of t cell retargeting hetero-dimeric immunoglobulins
|
EP3083686B2
(en)
|
2013-12-17 |
2023-03-22 |
F. Hoffmann-La Roche AG |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
AU2014364606A1
(en)
|
2013-12-17 |
2016-07-07 |
Genentech, Inc. |
Combination therapy comprising OX40 binding agonists and PD-1 axis binding antagonists
|
GB201322626D0
(en)
|
2013-12-19 |
2014-02-05 |
Immutep S A |
Combined preparations for the treatment of cancer
|
WO2015148531A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
ES2775431T3
(en)
|
2014-03-28 |
2020-07-27 |
Xencor Inc |
Bispecific Antibodies Binding to CD38 and CD3
|
EP3126394B1
(en)
|
2014-03-31 |
2019-10-30 |
F.Hoffmann-La Roche Ag |
Anti-ox40 antibodies and methods of use
|
MX2016012779A
(en)
|
2014-03-31 |
2017-04-27 |
Genentech Inc |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists.
|
PL3166401T3
(en)
|
2014-07-09 |
2021-01-25 |
F. Hoffmann-La Roche Ag |
Ph adjustment to improve thaw recovery of cell banks
|
LT3177643T
(en)
|
2014-08-04 |
2019-08-12 |
F. Hoffmann-La Roche Ag |
Bispecific t cell activating antigen binding molecules
|
CN107074823B
(en)
|
2014-09-05 |
2021-05-04 |
基因泰克公司 |
Therapeutic compounds and their uses
|
CN107073125A
(en)
|
2014-09-19 |
2017-08-18 |
基因泰克公司 |
CBP/EP300 and BET inhibitor is used for the purposes for the treatment of cancer
|
CN107912040B
(en)
|
2014-10-10 |
2021-04-06 |
基因泰克公司 |
Pyrrolidine amide compounds as histone demethylase inhibitors
|
CN107073116A
(en)
|
2014-10-23 |
2017-08-18 |
依奈特制药公司 |
Use anti-NKG2A agent therapies cancer
|
US20160160290A1
(en)
|
2014-11-03 |
2016-06-09 |
Genentech, Inc. |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
AU2015343337A1
(en)
|
2014-11-03 |
2017-06-15 |
Genentech, Inc. |
Assays for detecting T cell immune subsets and methods of use thereof
|
US11773166B2
(en)
|
2014-11-04 |
2023-10-03 |
Ichnos Sciences SA |
CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production
|
WO2016073282A1
(en)
|
2014-11-06 |
2016-05-12 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and tigit inhibitors
|
MA40940A
(en)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
SUBSTITUTED PYRROLOPYRIDINES USED AS BROMODOMA INHIBITORS
|
JP6639497B2
(en)
|
2014-11-10 |
2020-02-05 |
ジェネンテック, インコーポレイテッド |
Bromodomain inhibitors and uses thereof
|
MA40943A
(en)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
SUBSTITUTED PYRROLOPYRIDINES USED AS BROMODOMA INHIBITORS
|
CA2967368A1
(en)
|
2014-11-17 |
2016-05-26 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
PT3221356T
(en)
|
2014-11-20 |
2020-10-29 |
Hoffmann La Roche |
T cell activating bispecific antigen binding molecules agiant folr1 and cd3
|
HRP20221083T1
(en)
|
2014-11-20 |
2022-11-25 |
F. Hoffmann - La Roche Ag |
COMBINED THERAPY WITH A BISPECIFIC ANTIGEN BINDING MOLECULE THAT ACTIVATES T CELLS AND AN ANTAGONIST OF PD-1 AXIS BINDING
|
JP7164949B2
(en)
|
2014-11-20 |
2022-11-02 |
エフ.ホフマン-ラ ロシュ アーゲー |
Common Light Chains and Methods of Use
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
WO2016086196A2
(en)
|
2014-11-26 |
2016-06-02 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cd38
|
MA55043A
(en)
|
2014-11-26 |
2021-12-29 |
Xencor Inc |
HETERODIMERIC ANTIGEN-BINDING ANTIGEN CD3 AND CD20 ANTIGEN
|
WO2016086200A1
(en)
|
2014-11-27 |
2016-06-02 |
Genentech, Inc. |
4,5,6,7-tetrahydro-1 h-pyrazolo[4,3-c]pyridin-3-amine compounds as cbp and/or ep300 inhibitors
|
WO2016091891A1
(en)
|
2014-12-09 |
2016-06-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Human monoclonal antibodies against axl
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
WO2016106340A2
(en)
|
2014-12-23 |
2016-06-30 |
Genentech, Inc. |
Compositions and methods for treating and diagnosing chemotherapy-resistant cancers
|
JP2018503373A
(en)
|
2014-12-30 |
2018-02-08 |
ジェネンテック, インコーポレイテッド |
Methods and compositions for cancer prognosis and treatment
|
JP6889661B2
(en)
|
2015-01-09 |
2021-06-18 |
ジェネンテック, インコーポレイテッド |
4,5-Dihydroimidazole derivative and its use as a histone dimethylase (KDM2B) inhibitor
|
GB201500374D0
(en)
|
2015-01-09 |
2015-02-25 |
Immutep S A |
Combined preparations for the treatment of cancer
|
WO2016112298A1
(en)
|
2015-01-09 |
2016-07-14 |
Genentech, Inc. |
Pyridazinone derivatives and their use in the treatment of cancer
|
JP6855379B2
(en)
|
2015-01-09 |
2021-04-07 |
ジェネンテック, インコーポレイテッド |
(Piperidin-3-yl) (naphthalene-2-yl) metanone derivatives and related compounds as inhibitors of histone demethylase KDM2B for the treatment of cancer
|
KR101776879B1
(en)
|
2015-01-19 |
2017-09-08 |
주식회사 녹십자 |
Pharmaceutical formulation comprising anti-egfr antibody
|
JP6709792B2
(en)
|
2015-01-29 |
2020-06-17 |
ジェネンテック, インコーポレイテッド |
Therapeutic compounds and uses thereof
|
JP6636031B2
(en)
|
2015-01-30 |
2020-01-29 |
ジェネンテック, インコーポレイテッド |
Therapeutic compounds and uses thereof
|
MA41598A
(en)
|
2015-02-25 |
2018-01-02 |
Constellation Pharmaceuticals Inc |
PYRIDAZINE THERAPEUTIC COMPOUNDS AND THEIR USES
|
WO2016135041A1
(en)
|
2015-02-26 |
2016-09-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Fusion proteins and antibodies comprising thereof for promoting apoptosis
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
AU2016246695A1
(en)
|
2015-04-07 |
2017-10-26 |
Genentech, Inc. |
Antigen binding complex having agonistic activity and methods of use
|
ES2835866T5
(en)
|
2015-05-12 |
2024-12-02 |
Hoffmann La Roche |
Therapeutic and diagnostic procedures for cancer
|
MX2017014736A
(en)
|
2015-05-29 |
2018-03-23 |
Genentech Inc |
Therapeutic and diagnostic methods for cancer.
|
AU2016274584A1
(en)
|
2015-06-08 |
2018-01-04 |
Genentech, Inc. |
Methods of treating cancer using anti-OX40 antibodies and PD-1 axis binding antagonists
|
EP3303399A1
(en)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-ox40 antibodies
|
CN107921143B
(en)
|
2015-06-15 |
2021-11-19 |
安吉奥开米公司 |
Method for treating leptomeningeal carcinomatosis
|
TW201710286A
(en)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
Binding proteins against VEGF, PDGF, and/or their receptors
|
WO2016205320A1
(en)
|
2015-06-17 |
2016-12-22 |
Genentech, Inc. |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
JP6946270B2
(en)
|
2015-08-26 |
2021-10-06 |
ファンダシオン デル セクトル プーブリコ エスタタル セントロ ナショナル デ インベスティゲーショネス オンコロジカス カルロス 3(エフ エス ピー クニオ) |
Condensed tricyclic compound as a protein kinase inhibitor
|
US11713358B2
(en)
|
2015-08-28 |
2023-08-01 |
Amunix Pharmaceuticals, Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
US10935544B2
(en)
|
2015-09-04 |
2021-03-02 |
Obi Pharma, Inc. |
Glycan arrays and method of use
|
CR20220186A
(en)
|
2015-09-25 |
2022-07-07 |
Genentech Inc |
Anti-tigit antibodies and methods of use
|
AR106188A1
(en)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
ANTI-CD19 HUMANIZED HUMAN ANTIBODIES AND METHODS OF USE
|
JP7044700B2
(en)
|
2015-10-02 |
2022-03-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Bispecific anti-CEAXCD3 T cell activating antigen binding molecule
|
CN108699136B
(en)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
Heterodimeric antibodies that bind CD3 and PSMA
|
IL313608A
(en)
|
2015-12-09 |
2024-08-01 |
Hoffmann La Roche |
Antibody against CD20 type II to reduce the formation of antibodies against drugs
|
US10906918B2
(en)
|
2015-12-16 |
2021-02-02 |
Genentech, Inc. |
Process for the preparation of tricyclic PI3K inhibitor compounds and methods for using the same for the treatment of cancer
|
EP3400246B1
(en)
|
2016-01-08 |
2020-10-21 |
H. Hoffnabb-La Roche Ag |
Methods of treating cea-positive cancers using pd-1 axis binding antagonists and anti-cea/anti-cd3 bispecific antibodies
|
KR20180119632A
(en)
|
2016-02-29 |
2018-11-02 |
제넨테크, 인크. |
Treatment and Diagnosis Methods for Cancer
|
UA125378C2
(en)
|
2016-03-14 |
2022-03-02 |
Універшітетет І Осло |
Engineered immunoglobulins with altered fcrn binding
|
MY198233A
(en)
|
2016-03-22 |
2023-08-15 |
Hoffmann La Roche |
Protease-Activated T Cell Bispecific Molecules
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
CA3019373A1
(en)
|
2016-03-29 |
2017-10-05 |
Geltor, Inc. |
Expression of proteins in gram-negative bacteria wherein the ratio of periplasmic volume to cytoplasmic volume is between 0.5:1 and 10:1
|
CN109311995A
(en)
|
2016-03-29 |
2019-02-05 |
台湾浩鼎生技股份有限公司 |
Antibodies, pharmaceutical compositions and methods
|
EP3443004A1
(en)
|
2016-04-14 |
2019-02-20 |
H. Hoffnabb-La Roche Ag |
Anti-rspo3 antibodies and methods of use
|
EP3443120A2
(en)
|
2016-04-15 |
2019-02-20 |
H. Hoffnabb-La Roche Ag |
Methods for monitoring and treating cancer
|
JP2019518426A
(en)
|
2016-04-15 |
2019-07-04 |
ジェネンテック, インコーポレイテッド |
Cancer diagnosis and treatment method
|
KR20190003958A
(en)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
Treatment and monitoring of cancer
|
CN109379889A
(en)
|
2016-04-22 |
2019-02-22 |
台湾浩鼎生技股份有限公司 |
Cancer immunotherapy by immune activation or immunomodulation via antigens of the GLOBO series
|
US20190151346A1
(en)
|
2016-05-10 |
2019-05-23 |
INSERM (Institute National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
CN109415441B
(en)
|
2016-05-24 |
2023-04-07 |
英斯梅德股份有限公司 |
Antibodies and methods of making same
|
EP3464270B1
(en)
|
2016-05-24 |
2022-02-23 |
Genentech, Inc. |
Heterocyclic inhibitors of cbp/ep300 and their use in the treatment of cancer
|
WO2017205538A1
(en)
|
2016-05-24 |
2017-11-30 |
Genentech, Inc. |
Pyrazolopyridine derivatives for the treatment of cancer
|
KR102439911B1
(en)
|
2016-06-03 |
2022-09-05 |
어레이 바이오파마 인크. |
Pharmaceutical combination preparation
|
US20200129519A1
(en)
|
2016-06-08 |
2020-04-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
IL263542B2
(en)
|
2016-06-14 |
2024-10-01 |
Xencor Inc |
Bispecific checkpoint inhibitor antibodies
|
WO2017218698A1
(en)
|
2016-06-15 |
2017-12-21 |
Sutro Biopharma, Inc. |
Antibodies with engineered ch2 domains, compositions thereof and methods of using the same
|
MX2018016265A
(en)
|
2016-06-28 |
2019-07-04 |
Xencor Inc |
Heterodimeric antibodies that bind somatostatin receptor 2.
|
CA3032049C
(en)
|
2016-07-27 |
2023-11-07 |
Obi Pharma, Inc. |
Immunogenic/therapeutic glycan compositions and uses thereof
|
WO2018023121A1
(en)
|
2016-07-29 |
2018-02-01 |
Obi Pharma, Inc. |
Human antibodies, pharmaceutical compositions and methods
|
CN109963871A
(en)
|
2016-08-05 |
2019-07-02 |
豪夫迈·罗氏有限公司 |
Multivalence and multi-epitope Antibody and application method with agonist activity
|
CN109476748B
(en)
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
Methods for treatment and diagnosis of cancer
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP7022123B2
(en)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Bispecific antibody against CD3
|
KR20190072528A
(en)
|
2016-10-06 |
2019-06-25 |
제넨테크, 인크. |
Treatment and Diagnosis Methods for Cancer
|
US10501543B2
(en)
|
2016-10-14 |
2019-12-10 |
Xencor, Inc. |
IL15/IL15Rα heterodimeric Fc-fusion proteins
|
WO2018081648A2
(en)
|
2016-10-29 |
2018-05-03 |
Genentech, Inc. |
Anti-mic antibidies and methods of use
|
BR112019010356A2
(en)
|
2016-11-21 |
2019-08-27 |
Obi Pharma Inc |
carbohydrate molecule, antibody-antibody conjugate (adc), composition, method for preparing the composition, method for treating cancer in an individual, method for inducing or ameliorating the immune reaction in an individual in need thereof, drug-antibody conjugate compound, use of an antibody-drug conjugate compound, method for determining therapeutic efficacy of adcc cancer cells, and method for imaging an individual
|
MX2019007433A
(en)
|
2016-12-22 |
2019-08-16 |
Genentech Inc |
Methods and formulations for reducing reconstitution time of lyophilized polypeptides.
|
EP3589754B1
(en)
|
2017-03-01 |
2023-06-28 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
JP2020516638A
(en)
|
2017-04-13 |
2020-06-11 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
Interleukin 2 immunoconjugates, CD40 agonists, and optional PD-1 axis binding antagonists for use in a method of treating cancer
|
CN108948206B
(en)
*
|
2017-05-23 |
2022-08-23 |
赵磊 |
anti-EGFR/PD-1 double-targeting antibody, preparation method and application thereof
|
CN111132733A
(en)
|
2017-06-30 |
2020-05-08 |
Xencor股份有限公司 |
Targeted heterodimeric Fc fusion proteins containing IL-15/IL-15R α and an antigen binding domain
|
EP3655034A1
(en)
|
2017-07-21 |
2020-05-27 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
KR102713874B1
(en)
|
2017-08-11 |
2024-10-10 |
제넨테크, 인크. |
Anti-CD8 antibodies and uses thereof
|
KR102208378B1
(en)
|
2017-08-17 |
2021-01-28 |
주식회사 녹십자 |
Pharmaceutical formulation comprising anti-egfr antibody
|
WO2019051296A1
(en)
|
2017-09-08 |
2019-03-14 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
US11180541B2
(en)
|
2017-09-28 |
2021-11-23 |
Geltor, Inc. |
Recombinant collagen and elastin molecules and uses thereof
|
EP3710001A4
(en)
|
2017-10-27 |
2021-07-14 |
University Of Virginia Patent Foundation |
COMPOUNDS AND PROCEDURES FOR REGULATING, LIMITING OR INHIBITING AVIL EXPRESSION
|
KR20200075860A
(en)
|
2017-11-06 |
2020-06-26 |
제넨테크, 인크. |
How to diagnose and treat cancer
|
CA3082383A1
(en)
|
2017-11-08 |
2019-05-16 |
Xencor, Inc. |
Bispecific and monospecific antibodies using novel anti-pd-1 sequences
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
SG11202005732XA
(en)
|
2017-12-19 |
2020-07-29 |
Xencor Inc |
Engineered il-2 fc fusion proteins
|
JP7475275B2
(en)
|
2018-02-08 |
2024-04-26 |
ジェネンテック, インコーポレイテッド |
Bispecific antigen-binding molecules and methods of use thereof
|
TW202000702A
(en)
|
2018-02-26 |
2020-01-01 |
美商建南德克公司 |
Dosing for treatment with anti-TIGIT and anti-PD-L1 antagonist antibodies
|
WO2019195623A2
(en)
|
2018-04-04 |
2019-10-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
WO2019204665A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Pd-1 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and pd-1 antigen binding domains and uses thereof
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
CN112351999A
(en)
|
2018-05-18 |
2021-02-09 |
第一三共株式会社 |
anti-MUC 1 antibody-drug conjugates
|
US20210363590A1
(en)
|
2018-05-21 |
2021-11-25 |
Nanostring Technologies, Inc. |
Molecular gene signatures and methods of using same
|
MX2020014091A
(en)
|
2018-06-23 |
2021-05-27 |
Genentech Inc |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor.
|
TWI853822B
(en)
|
2018-06-27 |
2024-09-01 |
台灣浩鼎生技股份有限公司 |
Glycosynthase variants for glycoprotein engineering and methods of use
|
BR112020025623A2
(en)
|
2018-07-03 |
2021-03-23 |
Bristol-Myers Squibb Company |
methods of producing recombinant proteins
|
EP3823611A1
(en)
|
2018-07-18 |
2021-05-26 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
WO2020028909A1
(en)
|
2018-08-03 |
2020-02-06 |
Brown University |
Oral formulations with increased uptake
|
EP3847154A1
(en)
|
2018-09-03 |
2021-07-14 |
F. Hoffmann-La Roche AG |
Carboxamide and sulfonamide derivatives useful as tead modulators
|
WO2020061060A1
(en)
|
2018-09-19 |
2020-03-26 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
WO2020061349A1
(en)
|
2018-09-21 |
2020-03-26 |
Genentech, Inc. |
Diagnostic methods for triple-negative breast cancer
|
KR20210069641A
(en)
|
2018-10-03 |
2021-06-11 |
젠코어 인코포레이티드 |
IL-12 heterodimeric Fc-fusion protein
|
EP3864127A1
(en)
|
2018-10-10 |
2021-08-18 |
Boehringer Ingelheim International GmbH |
Method for membrane gas transfer in high density bioreactor culture
|
EP3863672A4
(en)
|
2018-10-11 |
2022-06-29 |
The Scripps Research Institute |
Antibody compounds with reactive arginine and related antibody drug conjugates
|
KR20210079311A
(en)
|
2018-10-18 |
2021-06-29 |
제넨테크, 인크. |
Diagnosis and treatment methods for sarcoma renal cancer
|
WO2020136145A2
(en)
|
2018-12-26 |
2020-07-02 |
Innate Pharma |
Leucocyte immunoglobulin-like receptor neutralizing antibodies
|
MX2021007797A
(en)
|
2018-12-28 |
2021-10-26 |
Kyowa Kirin Co Ltd |
BISPECIFIC ANTIBODY BINDING TO TfR.
|
JP2022519649A
(en)
|
2019-02-08 |
2022-03-24 |
ジェネンテック, インコーポレイテッド |
How to diagnose and treat cancer
|
SG11202108707WA
(en)
|
2019-02-27 |
2021-09-29 |
Epiaxis Therapeutics Pty Ltd |
Methods and agents for assessing t-cell function and predicting response to therapy
|
BR112021016923A2
(en)
|
2019-02-27 |
2021-11-03 |
Genentech Inc |
Methods for treating a patient with hematologic cancer, methods for treating a patient with relapsed or refractory mm, methods for treating a patient having a relapsed or refractory lnh, and kits
|
SG11202109406TA
(en)
|
2019-03-01 |
2021-09-29 |
Xencor Inc |
Heterodimeric antibodies that bind enpp3 and cd3
|
EA202192654A1
(en)
*
|
2019-03-29 |
2021-12-30 |
Грин Кросс Корпорейшн |
FUNCTION PROTEIN CONTAINING ANTI-MESOTHELIN ANTIBODY, ANTI-CD3 ANTIBODY OR ANTI-EGFR ANTIBODY, BISPECIFIC OR TRISPECIFIC ANTIBODY CONTAINING IT AND THEIR USES
|
KR20210145152A
(en)
|
2019-04-01 |
2021-12-01 |
제넨테크, 인크. |
Compositions and methods for stabilization of protein-containing formulations
|
EP3953380A4
(en)
|
2019-04-12 |
2023-01-25 |
Geltor, Inc. |
Recombinant elastin and production thereof
|
WO2020223233A1
(en)
|
2019-04-30 |
2020-11-05 |
Genentech, Inc. |
Prognostic and therapeutic methods for colorectal cancer
|
MX2021013222A
(en)
|
2019-05-03 |
2022-01-06 |
Genentech Inc |
Methods of treating cancer with an anti-pd-l1 antibody.
|
CN114269749B
(en)
|
2019-06-10 |
2024-10-01 |
苏特罗生物制药公司 |
5H-pyrrolo [3,2-d ] pyrimidine-2, 4-diamino compounds and antibody conjugates thereof
|
JP2022536800A
(en)
|
2019-06-17 |
2022-08-18 |
ストロ バイオファーマ インコーポレーテッド |
1-(4-(aminomethyl)benzyl)-2-butyl-2H-pyrazolo[3,4-C]quinolin-4-amine derivatives and related compounds as TOLL-like receptor (TLR) 7/8 agonists, and antibody drug conjugates thereof for use in cancer therapy and diagnosis
|
CN112300279A
(en)
|
2019-07-26 |
2021-02-02 |
上海复宏汉霖生物技术股份有限公司 |
Methods and compositions directed to anti-CD 73 antibodies and variants
|
JP2022543781A
(en)
|
2019-08-01 |
2022-10-14 |
ブリストル-マイヤーズ スクイブ カンパニー |
Method for improving protein productivity in fed-batch cell culture
|
CN114616250B
(en)
|
2019-09-04 |
2024-11-08 |
豪夫迈·罗氏有限公司 |
CD8 binding agents and uses thereof
|
JP2022548978A
(en)
|
2019-09-27 |
2022-11-22 |
ジェネンテック, インコーポレイテッド |
Dosing for Treatment with Drugs Anti-TIGIT and Anti-PD-L1 Antagonist Antibodies
|
WO2021083949A1
(en)
|
2019-10-29 |
2021-05-06 |
F. Hoffmann-La Roche Ag |
Bifunctional compounds for the treatment of cancer
|
MX2022005400A
(en)
|
2019-11-06 |
2022-05-24 |
Genentech Inc |
Diagnostic and therapeutic methods for treatment of hematologic cancers.
|
AU2020381458A1
(en)
|
2019-11-13 |
2022-05-12 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
US20230022576A1
(en)
|
2019-11-19 |
2023-01-26 |
Protalix Ltd. |
Removal of constructs from transformed cells
|
PH12022551419A1
(en)
|
2019-12-13 |
2023-11-20 |
Genentech Inc |
Anti-ly6g6d antibodies and methods of use
|
EP4076667A1
(en)
|
2019-12-20 |
2022-10-26 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
EP4114852A1
(en)
|
2020-03-03 |
2023-01-11 |
Sutro Biopharma, Inc. |
Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use
|
WO2021177980A1
(en)
|
2020-03-06 |
2021-09-10 |
Genentech, Inc. |
Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
|
JP2023520515A
(en)
|
2020-04-03 |
2023-05-17 |
ジェネンテック, インコーポレイテッド |
Therapeutic and diagnostic methods for cancer
|
IL297545A
(en)
|
2020-04-26 |
2022-12-01 |
Biocytogen Pharmaceuticals Beijing Co Ltd |
Modified immunoglobulins
|
WO2021222167A1
(en)
|
2020-04-28 |
2021-11-04 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
EP3915576A1
(en)
|
2020-05-28 |
2021-12-01 |
Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron |
Chimeric antigen receptors specific for p95her2 and uses thereof
|
IL299039A
(en)
|
2020-06-16 |
2023-02-01 |
Genentech Inc |
Methods and compositions for treating triple-negative breast cancer
|
EP4168118A1
(en)
|
2020-06-18 |
2023-04-26 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
CR20220637A
(en)
|
2020-06-19 |
2023-01-31 |
Hoffmann La Roche |
Antibodies binding to cd3 and cd19
|
CN115997123A
(en)
|
2020-06-30 |
2023-04-21 |
国家医疗保健研究所 |
Methods for predicting risk of recurrence and/or death of solid cancer patients after preoperative adjuvant therapy
|
WO2022002874A1
(en)
|
2020-06-30 |
2022-01-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapy and radical surgery
|
EP3939999A1
(en)
|
2020-07-14 |
2022-01-19 |
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
JP2023536602A
(en)
|
2020-08-03 |
2023-08-28 |
ジェネンテック, インコーポレイテッド |
Diagnostic and therapeutic methods for lymphoma
|
WO2022036146A1
(en)
|
2020-08-12 |
2022-02-17 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
KR20230073270A
(en)
|
2020-09-22 |
2023-05-25 |
브리스톨-마이어스 스큅 컴퍼니 |
Methods of producing therapeutic proteins
|
MX2023003338A
(en)
|
2020-09-23 |
2023-06-14 |
Erasca Inc |
Tricyclic pyridones and pyrimidones.
|
WO2022076462A1
(en)
|
2020-10-05 |
2022-04-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2022074646A1
(en)
|
2020-10-05 |
2022-04-14 |
Protalix Ltd. |
Dicer-like knock-out plant cells
|
WO2022103983A2
(en)
|
2020-11-11 |
2022-05-19 |
Sutro Biopharma, Inc. |
Fluorenylmethyloxycarbonyl and fluorenylmethylaminocarbonyl compounds, protein conjugates thereof, and methods for their use
|
US20230107642A1
(en)
|
2020-12-18 |
2023-04-06 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
PE20231505A1
(en)
|
2021-02-12 |
2023-09-26 |
Hoffmann La Roche |
BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER
|
CA3212665A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
KR20230154311A
(en)
|
2021-03-10 |
2023-11-07 |
젠코어 인코포레이티드 |
Heterodimeric antibodies binding to CD3 and GPC3
|
KR20240005691A
(en)
|
2021-04-30 |
2024-01-12 |
에프. 호프만-라 로슈 아게 |
Dosage for combination therapy with anti-CD20/anti-CD3 bispecific antibody and anti-CD79B antibody drug conjugate
|
EP4347603A1
(en)
|
2021-05-25 |
2024-04-10 |
Erasca, Inc. |
Sulfur-containing heteroaromatic tricyclic kras inhibitors
|
US20240293558A1
(en)
|
2021-06-16 |
2024-09-05 |
Erasca, Inc. |
Kras inhibitor conjugates
|
EP4377338A2
(en)
|
2021-07-27 |
2024-06-05 |
Novab, Inc. |
Engineered vlrb antibodies with immune effector functions
|
WO2023015234A1
(en)
|
2021-08-05 |
2023-02-09 |
Bristol-Myers Squibb Company |
Cell culture methods for producing therapeutic proteins
|
EP4384522A1
(en)
|
2021-08-10 |
2024-06-19 |
Erasca, Inc. |
Selective kras inhibitors
|
WO2023049687A1
(en)
|
2021-09-21 |
2023-03-30 |
Bristol-Myers Squibb Company |
Methods of controlling the level of dissolved oxygen (do) in a solution comprising a recombinant protein in a storage container
|
WO2023097195A1
(en)
|
2021-11-24 |
2023-06-01 |
Genentech, Inc. |
Therapeutic indazole compounds and methods of use in the treatment of cancer
|
JP2024543912A
(en)
|
2021-11-24 |
2024-11-26 |
ジェネンテック, インコーポレイテッド |
Bicyclic therapeutic compounds and methods of use in the treatment of cancer - Patents.com
|
WO2023164487A1
(en)
|
2022-02-22 |
2023-08-31 |
Brown University |
Compositions and methods to achieve systemic uptake of particles following oral or mucosal administration
|
EP4253418A1
(en)
|
2022-03-29 |
2023-10-04 |
Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron |
Immune cells expressing chimeric antigen receptors and bispecific antibodies and uses thereof
|
EP4504780A1
(en)
|
2022-04-01 |
2025-02-12 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
CN119317641A
(en)
|
2022-05-11 |
2025-01-14 |
基因泰克公司 |
Administration for treatment with anti-FCRH 5/anti-CD 3 bispecific antibodies
|
IL317449A
(en)
|
2022-06-07 |
2025-02-01 |
Genentech Inc |
Method for determining the efficacy of a lung cancer treatment comprising an anti-pd-l1 antagonist and an anti-tigit antagonist antibody
|
IL316919A
(en)
|
2022-06-27 |
2025-01-01 |
Sutro Biopharma Inc |
Beta-glucuronide carrier linkers, protein conjugates thereof and methods therefor
|
AU2023305619A1
(en)
|
2022-07-13 |
2025-01-23 |
F. Hoffmann-La Roche Ag |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024015229A1
(en)
|
2022-07-15 |
2024-01-18 |
Sutro Biopharma, Inc. |
Protease/enzyme cleavable linker-payloads and protein conjugates
|
TW202413433A
(en)
|
2022-07-19 |
2024-04-01 |
美商建南德克公司 |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
WO2024033457A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
AU2023322638A1
(en)
|
2022-08-11 |
2024-11-28 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
AU2023322637A1
(en)
|
2022-08-11 |
2024-11-14 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024085242A2
(en)
|
2022-10-21 |
2024-04-25 |
Kawasaki Institute Of Industrial Promotion |
Non-fouling or super stealth vesicle
|
TW202426505A
(en)
|
2022-10-25 |
2024-07-01 |
美商建南德克公司 |
Therapeutic and diagnostic methods for cancer
|
EP4406973A1
(en)
|
2023-01-27 |
2024-07-31 |
Fundació Privada Institut de Recerca de la SIDA-Caixa |
Antibodies and uses thereof for the treatment of infections caused by enveloped viruses
|
TW202434206A
(en)
|
2023-02-17 |
2024-09-01 |
美商伊瑞斯卡公司 |
Kras inhibitors
|
WO2024233341A1
(en)
|
2023-05-05 |
2024-11-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024254455A1
(en)
|
2023-06-08 |
2024-12-12 |
Genentech, Inc. |
Macrophage signatures for diagnostic and therapeutic methods for lymphoma
|
WO2025024257A1
(en)
|
2023-07-21 |
2025-01-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
WO2025029832A2
(en)
|
2023-07-31 |
2025-02-06 |
Sutro Biopharma, Inc. |
Sting agonist compounds and conjugates
|