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AU5418290A - Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections - Google Patents

Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections

Info

Publication number
AU5418290A
AU5418290A AU54182/90A AU5418290A AU5418290A AU 5418290 A AU5418290 A AU 5418290A AU 54182/90 A AU54182/90 A AU 54182/90A AU 5418290 A AU5418290 A AU 5418290A AU 5418290 A AU5418290 A AU 5418290A
Authority
AU
Australia
Prior art keywords
phosphorodithioates
polynucleotide
therapeutic agents
retroviral infections
retroviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54182/90A
Inventor
Marvin H. Caruthers
William S. Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Patents Inc
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of AU5418290A publication Critical patent/AU5418290A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
AU54182/90A 1989-03-31 1990-03-28 Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections Abandoned AU5418290A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33224789A 1989-03-31 1989-03-31
US332247 1989-03-31

Publications (1)

Publication Number Publication Date
AU5418290A true AU5418290A (en) 1990-11-05

Family

ID=23297385

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54182/90A Abandoned AU5418290A (en) 1989-03-31 1990-03-28 Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections

Country Status (2)

Country Link
AU (1) AU5418290A (en)
WO (1) WO1990012022A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626305B2 (en) * 1988-05-26 1992-07-30 University Patents Inc. Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
AU633911B2 (en) * 1989-04-18 1993-02-11 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756496B1 (en) 1988-09-23 2004-06-29 Isis Pharmaceuticals, Inc. Nucleoside hydrogen phosphonodithioate diesters and activated phosphonodithioate analogues
US5194599A (en) * 1988-09-23 1993-03-16 Gilead Sciences, Inc. Hydrogen phosphonodithioate compositions
EP0463712A3 (en) * 1990-06-27 1992-04-08 University Patents, Inc. Polynucleotide phosphorodithioates as therapeutic agents for retroviral infections
DK0464638T3 (en) * 1990-07-02 1997-10-13 Hoechst Ag Oligonucleotide analogs with terminal 3-3 or 5-5 internucleotide bonds.
JPH07501314A (en) * 1991-05-10 1995-02-09 ハイブライドン　インコーポレイテッド 3'-end-capped oligonucleotide
WO1994017792A2 (en) * 1993-01-27 1994-08-18 Affymax Technologies N.V. Compositions and methods for transdermal drug delivery
CA2114355A1 (en) * 1993-01-29 1994-07-30 Hidehiko Furukawa Modified oligodeoxyribonucleotides, their preparation and their therapeutic use
AT407639B (en) * 1993-12-13 2001-05-25 Christian Dr Noe MODIFIED OLIGONUCLEOTIDS, METHOD FOR THE PRODUCTION THEREOF AND USE AS ACTIVE SUBSTANCES FOR THE PRODUCTION OF MEDICINAL PRODUCTS
US8338094B2 (en) * 2007-11-27 2012-12-25 Bio-Rad Laboratories, Inc. Reduced inhibition of one-step RT-PCR
TW201929870A (en) * 2017-12-22 2019-08-01 丹麥商羅氏創新中心哥本哈根有限公司 Oligonucleotides comprising a phosphorodithioate internucleoside linkage

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451997A (en) * 1965-11-30 1969-06-24 Kyowa Hakko Kogyo Kk Monothio-phosphate ester catalysis for preparation of ribonucleoside derivatives
DE2122529A1 (en) * 1971-05-06 1972-12-14 Max Planck Gesellschaft zur Förde rung der Wissenschaften e V , 3400 Gottin gen Thiophosphate analogs of the nucleoside di and tnphosphate and processes for their preparation
US3853844A (en) * 1972-08-04 1974-12-10 R Robins Nucleoside 3{40 ,5{40 ,-cyclic phosphorothioates
US4415732A (en) * 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
US4668777A (en) * 1981-03-27 1987-05-26 University Patents, Inc. Phosphoramidite nucleoside compounds
US4373071A (en) * 1981-04-30 1983-02-08 City Of Hope Research Institute Solid-phase synthesis of polynucleotides
US4728730A (en) * 1984-09-12 1988-03-01 Wisconsin Alumini Research Foundation Synthesis of nucleoside thiophosphoanhydrides
US4808708A (en) * 1985-11-02 1989-02-28 Toagosei Chemical Industry Co., Ltd. Phosphorsulfide derivatives of deoxynucleosides or deoxynucleotides and their uses

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU626305B2 (en) * 1988-05-26 1992-07-30 University Patents Inc. Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
AU633911B2 (en) * 1989-04-18 1993-02-11 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Novel oligodeoxynucleotides with 5'-linked chemical groups, method of production thereof and use thereof

Also Published As

Publication number Publication date
WO1990012022A1 (en) 1990-10-18

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