[go: up one dir, main page]

AU5319396A - Thiono triester modified antisense oligodeoxynucleotide phosphorothioates - Google Patents

Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Info

Publication number
AU5319396A
AU5319396A AU53193/96A AU5319396A AU5319396A AU 5319396 A AU5319396 A AU 5319396A AU 53193/96 A AU53193/96 A AU 53193/96A AU 5319396 A AU5319396 A AU 5319396A AU 5319396 A AU5319396 A AU 5319396A
Authority
AU
Australia
Prior art keywords
modified antisense
antisense oligodeoxynucleotide
thiono
oligodeoxynucleotide phosphorothioates
triester modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53193/96A
Inventor
Jimmy X Tang
Jin Yan Tang
Zhaoda Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aceragen Inc
Original Assignee
Hybridon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybridon Inc filed Critical Hybridon Inc
Publication of AU5319396A publication Critical patent/AU5319396A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
AU53193/96A 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates Abandoned AU5319396A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40916995A 1995-03-23 1995-03-23
US409169 1995-03-23
PCT/US1996/003843 WO1996029337A1 (en) 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Publications (1)

Publication Number Publication Date
AU5319396A true AU5319396A (en) 1996-10-08

Family

ID=23619328

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53193/96A Abandoned AU5319396A (en) 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Country Status (4)

Country Link
JP (1) JPH11502818A (en)
AU (1) AU5319396A (en)
CA (1) CA2216284A1 (en)
WO (1) WO1996029337A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734022B2 (en) * 1997-05-01 2001-05-31 University Of Sydney, The Nucleic acid molecules specific for bacterial antigens and uses thereof

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2215097A (en) * 1996-03-14 1997-10-01 Hybridon, Inc. Selected oligonucleotides with anti-cytomegalovirus activity
US6776986B1 (en) 1996-06-06 2004-08-17 Novartis Ag Inhibition of HIV-1 replication by antisense RNA expression
WO1998004575A2 (en) * 1996-07-31 1998-02-05 Gilead Sciences, Inc. Lipophilic oligonucleotide analogs
WO1998007734A1 (en) * 1996-08-21 1998-02-26 Hybridon, Inc. Oligonucleotide prodrugs
AU772847B2 (en) 1998-11-12 2004-05-06 Invitrogen Corporation Transfection reagents
US9809824B2 (en) 2004-12-13 2017-11-07 The United States Of America, Represented By The Secretary, Department Of Health And Human Services CpG oligonucleotide prodrugs, compositions thereof and associated therapeutic methods
EP3169310A1 (en) 2014-07-15 2017-05-24 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6603690A (en) * 1989-10-05 1991-04-28 University Patents Inc. Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
WO1994002499A1 (en) * 1992-07-27 1994-02-03 Hybridon, Inc. Oligonucleotide alkylphosphonothioates
NZ261480A (en) * 1993-01-08 1997-05-26 Hybridon Inc Preparation of dimeric nucleotide derivatives containing phosphonothionate internucleotide linkages

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734022B2 (en) * 1997-05-01 2001-05-31 University Of Sydney, The Nucleic acid molecules specific for bacterial antigens and uses thereof

Also Published As

Publication number Publication date
CA2216284A1 (en) 1996-09-26
WO1996029337A1 (en) 1996-09-26
JPH11502818A (en) 1999-03-09

Similar Documents

Publication Publication Date Title
AU9023798A (en) Mdm2-specific antisense oligonucleotides
AU3222795A (en) Antitumor antisense oligonucleotides
AU8016494A (en) Antisense oligonucleotide generators
AU4565297A (en) Identifying antisense oligonucleotide binding
GB9510718D0 (en) Antisense oligonucleotides
AU4542199A (en) Gaming console
AU8938098A (en) Liposomes containing oligonucleotides
AU5979296A (en) Peptide-enhanced cationic lipid transfections
AU6912996A (en) Liposomal phosphodiester, phosphorothioate, and p-ethoxy oligonucleotides
EP0840744A4 (en) Phosphonic acid-based cationic lipids
AU5441896A (en) Cooperative oligonucleotides
AU3811897A (en) Antisense oligonucleotides as antibacterial agents
AU8425498A (en) Machine for forming cones
AU5259498A (en) Antisense oligonucleotides
AU4156197A (en) Oligonucleotide prodrugs
GB9505438D0 (en) Antisense oligonucleotides
AU8726898A (en) Egg tray
AU5319396A (en) Thiono triester modified antisense oligodeoxynucleotide phosphorothioates
AU3126595A (en) Antisense oligonucleotides of pleiotrophin
GB2306478B (en) Phosphorus compounds
AUPP086797A0 (en) Gaming system
AU8637598A (en) Lipid removal
AU5372998A (en) Antisense oligonucleotides specific for cdk4
AU7364998A (en) Antisense oligonucleotides specific for thymidylate synthase
AU1710997A (en) Oligonucleotide analogs