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AU4862090A - Process for renaturing incorrect recombinants of insulin precursors - Google Patents

Process for renaturing incorrect recombinants of insulin precursors

Info

Publication number
AU4862090A
AU4862090A AU48620/90A AU4862090A AU4862090A AU 4862090 A AU4862090 A AU 4862090A AU 48620/90 A AU48620/90 A AU 48620/90A AU 4862090 A AU4862090 A AU 4862090A AU 4862090 A AU4862090 A AU 4862090A
Authority
AU
Australia
Prior art keywords
renaturing
insulin precursors
recombinants
incorrect
incorrect recombinants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU48620/90A
Other versions
AU628473B2 (en
Inventor
Michael Dorschug
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4862090A publication Critical patent/AU4862090A/en
Application granted granted Critical
Publication of AU628473B2 publication Critical patent/AU628473B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU48620/90A 1989-01-21 1990-01-19 Process for renaturing incorrect recombinants of insulin precursors Ceased AU628473B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3901718A DE3901718A1 (en) 1989-01-21 1989-01-21 METHOD FOR RENATURING INCORRECT RECOMBINANT OF INSULIN PREFERRED
DE3901718 1989-01-21

Publications (2)

Publication Number Publication Date
AU4862090A true AU4862090A (en) 1990-07-26
AU628473B2 AU628473B2 (en) 1992-09-17

Family

ID=6372511

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48620/90A Ceased AU628473B2 (en) 1989-01-21 1990-01-19 Process for renaturing incorrect recombinants of insulin precursors

Country Status (12)

Country Link
EP (1) EP0379162A3 (en)
JP (1) JPH02233698A (en)
AU (1) AU628473B2 (en)
CA (1) CA2008246A1 (en)
DE (1) DE3901718A1 (en)
FI (1) FI900295A0 (en)
HU (1) HU207526B (en)
IL (1) IL93114A0 (en)
NO (1) NO900277L (en)
NZ (1) NZ232177A (en)
PT (1) PT92906A (en)
ZA (1) ZA90395B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004382A1 (en) * 1990-09-05 1992-03-19 Bunge (Australia) Pty. Ltd. Solubilization of proteins in active forms
AU624894B2 (en) * 1989-01-21 1992-06-25 Hoechst Aktiengesellschaft Process for the preparation of an insulin precursor
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4405179A1 (en) * 1994-02-18 1995-08-24 Hoechst Ag Method of obtaining insulin with correctly connected cystine bridges
HU223718B1 (en) † 1994-12-29 2004-12-28 Savient Pharmaceuticals, Inc. Process for the production of human insulin starting with the expression of a hybrid peptide containing proinsulin
EP1592703B1 (en) 2003-01-31 2008-06-04 N.V. Organon Method for protein isolation in anoxic conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1154435A (en) * 1980-03-27 1983-09-27 Bruce H. Frank Process for producing an insulin precursor
DE3501641A1 (en) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt METHOD FOR OBTAINING INSULIN PRECURSORS FROM REACTION MIXTURES WHICH ARE INCLUDED IN THE FOLDING OF INSULIN PRECURSORS FROM THE CORRESPONDING S-SULPHONATES
DE3901719A1 (en) * 1989-01-21 1990-07-26 Hoechst Ag METHOD FOR PRODUCING AN INSULIN PREVENTE

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU624894B2 (en) * 1989-01-21 1992-06-25 Hoechst Aktiengesellschaft Process for the preparation of an insulin precursor
WO1992004382A1 (en) * 1990-09-05 1992-03-19 Bunge (Australia) Pty. Ltd. Solubilization of proteins in active forms
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents

Also Published As

Publication number Publication date
HU900196D0 (en) 1990-03-28
EP0379162A3 (en) 1991-10-16
NO900277L (en) 1990-07-23
FI900295A0 (en) 1990-01-18
DE3901718A1 (en) 1990-07-26
AU628473B2 (en) 1992-09-17
HU207526B (en) 1993-04-28
JPH02233698A (en) 1990-09-17
PT92906A (en) 1990-07-31
CA2008246A1 (en) 1990-07-21
HUT54179A (en) 1991-01-28
NZ232177A (en) 1991-11-26
ZA90395B (en) 1990-09-26
EP0379162A2 (en) 1990-07-25
NO900277D0 (en) 1990-01-19
IL93114A0 (en) 1990-11-05

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