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AU4504793A - Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination - Google Patents

Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination

Info

Publication number
AU4504793A
AU4504793A AU45047/93A AU4504793A AU4504793A AU 4504793 A AU4504793 A AU 4504793A AU 45047/93 A AU45047/93 A AU 45047/93A AU 4504793 A AU4504793 A AU 4504793A AU 4504793 A AU4504793 A AU 4504793A
Authority
AU
Australia
Prior art keywords
proteins
vaccination
diagnostics
preserving
denaturing conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45047/93A
Inventor
Jean-Jacques Madjar
Herve Poly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Publication of AU4504793A publication Critical patent/AU4504793A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU45047/93A 1992-06-30 1993-06-29 Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination Abandoned AU4504793A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9208051 1992-06-30
FR9208051A FR2692898B1 (en) 1992-06-30 1992-06-30 Method for obtaining membrane proteins, and use of these proteins for diagnostic or vaccination purposes.
PCT/FR1993/000654 WO1994000557A1 (en) 1992-06-30 1993-06-29 Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination

Publications (1)

Publication Number Publication Date
AU4504793A true AU4504793A (en) 1994-01-24

Family

ID=9431365

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45047/93A Abandoned AU4504793A (en) 1992-06-30 1993-06-29 Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination

Country Status (3)

Country Link
AU (1) AU4504793A (en)
FR (1) FR2692898B1 (en)
WO (1) WO1994000557A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914390A (en) * 1997-05-12 1999-06-22 Celtrix Pharmaceuticals, Inc. Methods for increasing yields of recombinant proteins
DE19801090A1 (en) * 1998-01-14 1999-07-15 Gerhard Haase Device for isolating of microorganisms from cell-containing fluids using standard syringes
FR2781676B1 (en) * 1998-07-31 2004-04-02 Pasteur Merieux Serums Vacc QUARTER OF HIV ENV GENE EXPRESSION PRODUCT
DE19939246A1 (en) 1999-08-19 2001-02-22 Phasys Gmbh M Refolding membrane proteins into their native or active form comprises solubilizing the protein in a first detergent and replacing the first detergent with a second detergent
WO2024056508A1 (en) 2022-09-15 2024-03-21 Cube Biotech Gmbh In vitro diagnostic method for detecting the presence of a target by using stabilized membrane proteins

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752473A (en) * 1984-10-12 1988-06-21 The Regents Of The University Of California Expression of glycosylated human influenza hemagglutinin proteins
EP0295859B1 (en) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Production of proteins in active forms
JPS6447435A (en) * 1987-08-18 1989-02-21 Oriental Yeast Co Ltd Dispersant for biologically active peptide
DE3787654D1 (en) * 1987-12-23 1993-11-04 Immuno Ag CELLULAR AMPHIPATIC PROTEINS IN AGGREGATED FORMS AND METHOD FOR THE PRODUCTION AND PURIFICATION OF THESE PROTEINS.
DE3809796A1 (en) * 1988-03-23 1989-10-05 Wolfgang Prof Dr Med Bredt PROCESS FOR CLEANING A 168 KD PROTEIN OF MYCOPLASMA PNEUMONIAE
AU640348B2 (en) * 1988-08-31 1993-08-26 Smithkline Beecham Corporation Vaccinal Polypeptides
WO1990013314A2 (en) * 1989-05-12 1990-11-15 Institut Pasteur Antigenes of the envelope transmembrane glycoprotein of a human retrovirus of the hiv-2 type, and antigens presenting with them an immunological relationship
CA2067766A1 (en) * 1989-10-24 1991-04-25 Richard I. Feldman Gastrin releasing peptide receptor
JPH03271233A (en) * 1990-03-19 1991-12-03 Inst Pasteur Induction of protection against viral infection by synergy between viral envelope glycoproteins and peptides corresponding to neutralizing epitopes of the glycoproteins
DD300690A5 (en) * 1990-03-23 1992-07-02 Univ Berlin Humboldt Process for the preparation of a derivative of the transmembrane protein Gp41 of the human immunodeficiency virus 1 (Penv 474-647) in E. Coli

Also Published As

Publication number Publication date
WO1994000557A1 (en) 1994-01-06
FR2692898B1 (en) 1995-06-02
FR2692898A1 (en) 1993-12-31

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