AU4499499A - A polypeptide structure for use as a scaffold - Google Patents

A polypeptide structure for use as a scaffold

Info

Publication number: AU4499499A
Authority: AU; Australia
Prior art keywords: scaffold; polypeptide structure; polypeptide
Prior art date: 1999-04-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU44994/99A

Inventor

Johan Desmet

Hendricus Hoogenboom

Simon Hufton

Erwin Sablon

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Fujirebio Europe NV SA

Original Assignee

Innogenetics NV SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-01

Filing date

1999-04-01

Publication date

2000-10-23

1999-04-01 Application filed by Innogenetics NV SA filed Critical Innogenetics NV SA

2000-10-23 Publication of AU4499499A publication Critical patent/AU4499499A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Crystallography & Structural Chemistry (AREA)
Virology (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Plant Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Peptides Or Proteins (AREA)

AU44994/99A 1999-04-01 1999-04-01 A polypeptide structure for use as a scaffold Abandoned AU4499499A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP1999/002283 WO2000060070A1 (en)	1999-04-01	1999-04-01	A polypeptide structure for use as a scaffold

Publications (1)

Publication Number	Publication Date
AU4499499A true AU4499499A (en)	2000-10-23

Family

ID=8167259

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU44994/99A Abandoned AU4499499A (en)	1999-04-01	1999-04-01	A polypeptide structure for use as a scaffold

Country Status (4)

Country	Link
EP (1)	EP1163339A1 (en)
AU (1)	AU4499499A (en)
CA (1)	CA2367212A1 (en)
WO (1)	WO2000060070A1 (en)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1318195A1 (en) *	2001-12-10	2003-06-11	CatchMabs B.V.	A structure for presenting desired peptide sequences
US9321832B2 (en)	2002-06-28	2016-04-26	Domantis Limited	Ligand
AU2003260786B2 (en)	2002-09-06	2008-03-13	Isogenica Limited	In vitro peptide expression libraray
WO2004101620A2 (en) *	2003-05-01	2004-11-25	Compound Therapeutics, Inc.	Serum albumin scaffold-based proteins and uses thereof
US20060008844A1 (en)	2004-06-17	2006-01-12	Avidia Research Institute	c-Met kinase binding proteins
US7749694B2 (en)	2004-12-31	2010-07-06	The Regents Of The University Of California	C-type lectin fold as a scaffold for massive sequence variation
US7700729B2 (en)	2006-05-15	2010-04-20	Avidbiotics Corporation	Modified bacteriocins and methods for their use
DK2021358T3 (en)	2006-05-15	2012-07-16	Avidbiotics Corp	Modified bacteriocins and methods for their use
US8445639B2 (en)	2006-05-15	2013-05-21	Avidbiotics Corporation	Recombinant bacteriophage and methods for their use
EP2136838B1 (en)	2007-03-08	2017-03-08	KaloBios Pharmaceuticals, Inc.	Epha3 antibodies for the treatment of solid tumors
KR101151805B1 (en)	2008-10-20	2012-06-01	광주과학기술원	Bipodal Peptide Binder
EA201101241A1 (en)	2009-03-06	2012-04-30	Калобайос Фармасьютиклз, Инк.	TREATMENT OF LEUKEMIA AND CHRONIC MYELOPROLIFERATIVE DISEASES BY ERP3 Antibodies
US8372952B2 (en)	2009-12-02	2013-02-12	Amgen Inc.	Binding proteins that bind to human FGFR1C, human β-klotho and both human FGFR1C and human β-klotho
EP3419667A4 (en) *	2016-02-26	2019-10-23	Imunexus Pty Ltd	Multi-specific molecules
CN109153728A (en)	2016-03-21	2019-01-04	埃尔斯塔治疗公司	Polyspecific and polyfunctional molecule and application thereof
IL262359B (en)	2016-04-13	2022-09-01	Vivia Biotech Sl	In vitro bite-activated T cells
WO2017210598A1 (en)	2016-06-03	2017-12-07	Amgen Inc.	Compositions and methods for treating an articular disorder
CN109906232B (en)	2016-09-23	2023-11-07	马伦戈治疗公司	Multispecific antibody molecules comprising lambda light chain and kappa light chain
WO2018151820A1 (en)	2017-02-16	2018-08-23	Elstar Therapeutics, Inc.	Multifunctional molecules comprising a trimeric ligand and uses thereof
WO2018195283A1 (en)	2017-04-19	2018-10-25	Elstar Therapeutics, Inc.	Multispecific molecules and uses thereof
CA3059769A1 (en)	2017-04-28	2018-11-01	Elstar Therapeutics, Inc.	Multispecific molecules comprising a non-immunoglobulin heterodimerization domain and uses thereof
JP2020522254A (en)	2017-05-31	2020-07-30	エルスターセラピューティクス，インコーポレイテッド	Multispecific molecules that bind myeloproliferative leukemia (MPL) proteins and uses thereof
WO2019035938A1 (en)	2017-08-16	2019-02-21	Elstar Therapeutics, Inc.	Multispecific molecules that bind to bcma and uses thereof
EP3720881A1 (en)	2017-12-08	2020-10-14	Elstar Therapeutics, Inc.	Multispecific molecules and uses thereof
WO2019139987A1 (en)	2018-01-09	2019-07-18	Elstar Therapeutics, Inc.	Calreticulin binding constructs and engineered t cells for the treatment of diseases
EP3765516A2 (en)	2018-03-14	2021-01-20	Elstar Therapeutics, Inc.	Multifunctional molecules and uses thereof
WO2019178362A1 (en)	2018-03-14	2019-09-19	Elstar Therapeutics, Inc.	Multifunctional molecules that bind to calreticulin and uses thereof
CN112955465A (en)	2018-07-03	2021-06-11	马伦戈治疗公司	anti-TCR antibody molecules and uses thereof
EP3856350A1 (en)	2018-09-27	2021-08-04	Marengo Therapeutics, Inc.	Csf1r/ccr2 multispecific antibodies
SG11202108955QA (en)	2019-02-21	2021-09-29	Marengo Therapeutics Inc	Antibody molecules that bind to nkp30 and uses thereof
SG11202109033XA (en)	2019-02-21	2021-09-29	Marengo Therapeutics Inc	Multifunctional molecules that bind to t cells and uses thereof to treat autoimmune disorders
WO2020172571A1 (en)	2019-02-21	2020-08-27	Elstar Therapeutics, Inc.	Multifunctional molecules that bind to t cell related cancer cells and uses thereof
GB2599229B (en)	2019-02-21	2024-04-24	Marengo Therapeutics Inc	Multifunctional molecules that bind to calreticulin and uses thereof
EP3927431A1 (en)	2019-02-21	2021-12-29	Marengo Therapeutics, Inc.	Anti-tcr antibody molecules and uses thereof
EP4084821A4 (en)	2020-01-03	2024-04-24	Marengo Therapeutics, Inc.	CD33-BINDING MULTIFUNCTIONAL MOLECULES AND THEIR USES
GB2612450A (en)	2020-04-24	2023-05-03	Marengo Therapeutics Inc	Multifunctional molecules that bind to T cell related cancer cells and uses thereof
AU2021333779A1 (en)	2020-08-26	2023-04-13	Marengo Therapeutics, Inc.	Methods of detecting TRBC1 or TRBC2
WO2022046920A2 (en)	2020-08-26	2022-03-03	Marengo Therapeutics, Inc.	Multifunctional molecules that bind to calreticulin and uses thereof
AU2021331076A1 (en)	2020-08-26	2023-04-06	Marengo Therapeutics, Inc.	Antibody molecules that bind to NKp30 and uses thereof
GB2623199A (en)	2021-04-08	2024-04-10	Marengo Therapeutics Inc	Multifunctional molecules binding to TCR and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5773253A (en) *	1993-01-22	1998-06-30	Bristol-Myers Squibb Company	MYPPPY variants of CTL A4 and uses thereof
AUPP221098A0 (en) *	1998-03-06	1998-04-02	Diatech Pty Ltd	V-like domain binding molecules
EP0947582A1 (en) *	1998-03-31	1999-10-06	Innogenetics N.V.	A polypeptide structure for use as a scaffold

1999
- 1999-04-01 AU AU44994/99A patent/AU4499499A/en not_active Abandoned
- 1999-04-01 CA CA002367212A patent/CA2367212A1/en not_active Abandoned
- 1999-04-01 WO PCT/EP1999/002283 patent/WO2000060070A1/en not_active Application Discontinuation
- 1999-04-01 EP EP99927740A patent/EP1163339A1/en not_active Withdrawn

Also Published As

Publication number	Publication date
WO2000060070A1 (en)	2000-10-12
CA2367212A1 (en)	2000-10-12
EP1163339A1 (en)	2001-12-19

Publication	Publication Date	Title
AU4499499A (en)	2000-10-23	A polypeptide structure for use as a scaffold
AU4606700A (en)	2000-11-21	A tissue engineering scaffold
AU7867000A (en)	2001-05-10	Snapshot virtual-templating
AU8018200A (en)	2001-05-14	A knowledge-engineering protocol-suite
AU4431000A (en)	2000-12-05	Novel use
AU6032100A (en)	2001-01-02	New compounds
AU5691800A (en)	2001-01-22	Structure
AU2598401A (en)	2001-07-09	A mobile outrigger scaffolding system
AU5706000A (en)	2001-01-31	Useful polypeptide
AU2201501A (en)	2001-06-25	Structure
AU9009298A (en)	1999-03-22	A scaffold structure
AUPQ488899A0 (en)	2000-02-03	Scaffolding
AU6483600A (en)	2001-03-13	Collision-resistant structure
AU2691500A (en)	2000-09-14	Novel polypeptide
AU2411601A (en)	2001-05-30	Mast
AU6550800A (en)	2001-03-05	Hepoxilin analogs
AUPQ078799A0 (en)	1999-06-24	New use
AU2669501A (en)	2001-06-12	New use
AU4778600A (en)	2000-12-12	Novel polypeptide
AU2109200A (en)	2000-08-07	Polypeptide
AU1228201A (en)	2001-05-08	Umlr polypeptides
AU6712600A (en)	2001-03-19	Polypeptides
AUPQ462399A0 (en)	2000-01-13	New use
AU3158701A (en)	2001-06-25	New use
AU2950900A (en)	2000-09-21	Arrangement related to a call procedure

Legal Events

Date	Code	Title	Description
2002-03-07	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase