AU4409899A - Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption - Google Patents
Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorptionInfo
- Publication number
- AU4409899A AU4409899A AU44098/99A AU4409899A AU4409899A AU 4409899 A AU4409899 A AU 4409899A AU 44098/99 A AU44098/99 A AU 44098/99A AU 4409899 A AU4409899 A AU 4409899A AU 4409899 A AU4409899 A AU 4409899A
- Authority
- AU
- Australia
- Prior art keywords
- noggin
- antagonists
- bone
- morphogenetic proteins
- bone resorption
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000007350 Bone Morphogenetic Proteins Human genes 0.000 title 1
- 108010007726 Bone Morphogenetic Proteins Proteins 0.000 title 1
- 208000006386 Bone Resorption Diseases 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 229940112869 bone morphogenetic protein Drugs 0.000 title 1
- 230000024279 bone resorption Effects 0.000 title 1
- 102000045246 noggin Human genes 0.000 title 1
- 108700007229 noggin Proteins 0.000 title 1
- 230000001575 pathological effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8708298P | 1998-05-28 | 1998-05-28 | |
US60087082 | 1998-05-28 | ||
PCT/US1999/012001 WO1999061044A1 (en) | 1998-05-28 | 1999-05-28 | Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4409899A true AU4409899A (en) | 1999-12-13 |
Family
ID=22203012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU44098/99A Abandoned AU4409899A (en) | 1998-05-28 | 1999-05-28 | Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU4409899A (en) |
WO (1) | WO1999061044A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1121132A4 (en) * | 1998-10-07 | 2004-03-24 | Univ Arkansas | METHOD AND COMPOSITIONS FOR INCREASING THE BONE WEIGHT |
AU773043B2 (en) * | 1998-10-07 | 2004-05-13 | Board Of Trustees Of The University Of Arkansas, The | In vitro and in vivo models for screening compounds to prevent glucocorticoid-induced bone destruction |
AU6510999A (en) * | 1998-10-07 | 2000-04-26 | Board Of Trustees Of The University Of Arkansas, The | Methods of screening for apoptosis-controlling agents for bone anabolic therapies and uses thereof |
US6660468B1 (en) | 1998-10-27 | 2003-12-09 | Board Of Trustees Of The University Of Arkansas | Vitro and in vivo models for screening compounds to prevent glucocorticoid-induced bone destruction |
GB2385052A (en) * | 2002-02-05 | 2003-08-13 | Leuven K U Res & Dev | Treatment of spondyloarthropathies |
US20070056050A1 (en) * | 2005-06-29 | 2007-03-08 | Clokie Cameron M L | PRODUCTION OF BONE MORPHOGENIC PROTEINS (BMPs) IN TRANSGENIC MAMMALS |
BRPI0714893A2 (en) * | 2006-09-05 | 2013-05-28 | Medarex Inc | isolated monoclonal antibody or antigen-binding portion thereof, antibody fragment, mimetic antibody, immunoconjugate, isolated nucleic acid molecule composition, expression vector, host cell, method for preparing an anti-bmp2 or anti-bmp4 antibody, Method for treating or preventing a disease associated with normal bone formation and ossification, hybridoma and method for preparing the antibody |
KR101163171B1 (en) | 2009-01-20 | 2012-07-19 | (주)케어젠 | Noggin derived Peptides and Uses Thereof |
WO2018115879A1 (en) | 2016-12-21 | 2018-06-28 | Mereo Biopharma 3 Limited | Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL106894A0 (en) * | 1992-09-03 | 1994-05-30 | Regeneron Pharma | Dorsal tissue affecting factor and compositions |
EP0662146B1 (en) * | 1992-09-03 | 2000-07-12 | The Regents Of The University Of California | Dorsal tissue affecting factor and compositions |
US5679783A (en) * | 1994-11-22 | 1997-10-21 | The Regents Of The University Of California | DNA encoding a tissue differentiation affecting factor |
NZ500577A (en) * | 1997-04-29 | 2001-02-23 | Regeneron Pharma | Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins |
-
1999
- 1999-05-28 AU AU44098/99A patent/AU4409899A/en not_active Abandoned
- 1999-05-28 WO PCT/US1999/012001 patent/WO1999061044A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1999061044A1 (en) | 1999-12-02 |
WO1999061044A9 (en) | 2000-02-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |