[go: up one dir, main page]

AU4409899A - Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption - Google Patents

Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption

Info

Publication number
AU4409899A
AU4409899A AU44098/99A AU4409899A AU4409899A AU 4409899 A AU4409899 A AU 4409899A AU 44098/99 A AU44098/99 A AU 44098/99A AU 4409899 A AU4409899 A AU 4409899A AU 4409899 A AU4409899 A AU 4409899A
Authority
AU
Australia
Prior art keywords
noggin
antagonists
bone
morphogenetic proteins
bone resorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44098/99A
Inventor
Etsuko Abe
Robert L. Jilka
Stavros C. Manolagas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arkansas System
Original Assignee
University of Arkansas at Fayetteville
University of Arkansas at Little Rock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Arkansas at Fayetteville, University of Arkansas at Little Rock filed Critical University of Arkansas at Fayetteville
Publication of AU4409899A publication Critical patent/AU4409899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU44098/99A 1998-05-28 1999-05-28 Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption Abandoned AU4409899A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8708298P 1998-05-28 1998-05-28
US60087082 1998-05-28
PCT/US1999/012001 WO1999061044A1 (en) 1998-05-28 1999-05-28 Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption

Publications (1)

Publication Number Publication Date
AU4409899A true AU4409899A (en) 1999-12-13

Family

ID=22203012

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44098/99A Abandoned AU4409899A (en) 1998-05-28 1999-05-28 Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption

Country Status (2)

Country Link
AU (1) AU4409899A (en)
WO (1) WO1999061044A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121132A4 (en) * 1998-10-07 2004-03-24 Univ Arkansas METHOD AND COMPOSITIONS FOR INCREASING THE BONE WEIGHT
AU773043B2 (en) * 1998-10-07 2004-05-13 Board Of Trustees Of The University Of Arkansas, The In vitro and in vivo models for screening compounds to prevent glucocorticoid-induced bone destruction
AU6510999A (en) * 1998-10-07 2000-04-26 Board Of Trustees Of The University Of Arkansas, The Methods of screening for apoptosis-controlling agents for bone anabolic therapies and uses thereof
US6660468B1 (en) 1998-10-27 2003-12-09 Board Of Trustees Of The University Of Arkansas Vitro and in vivo models for screening compounds to prevent glucocorticoid-induced bone destruction
GB2385052A (en) * 2002-02-05 2003-08-13 Leuven K U Res & Dev Treatment of spondyloarthropathies
US20070056050A1 (en) * 2005-06-29 2007-03-08 Clokie Cameron M L PRODUCTION OF BONE MORPHOGENIC PROTEINS (BMPs) IN TRANSGENIC MAMMALS
BRPI0714893A2 (en) * 2006-09-05 2013-05-28 Medarex Inc isolated monoclonal antibody or antigen-binding portion thereof, antibody fragment, mimetic antibody, immunoconjugate, isolated nucleic acid molecule composition, expression vector, host cell, method for preparing an anti-bmp2 or anti-bmp4 antibody, Method for treating or preventing a disease associated with normal bone formation and ossification, hybridoma and method for preparing the antibody
KR101163171B1 (en) 2009-01-20 2012-07-19 (주)케어젠 Noggin derived Peptides and Uses Thereof
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL106894A0 (en) * 1992-09-03 1994-05-30 Regeneron Pharma Dorsal tissue affecting factor and compositions
EP0662146B1 (en) * 1992-09-03 2000-07-12 The Regents Of The University Of California Dorsal tissue affecting factor and compositions
US5679783A (en) * 1994-11-22 1997-10-21 The Regents Of The University Of California DNA encoding a tissue differentiation affecting factor
NZ500577A (en) * 1997-04-29 2001-02-23 Regeneron Pharma Human cerberus protein that regulates cell function, induce neural development or antagonise bone morphogenic proteins

Also Published As

Publication number Publication date
WO1999061044A1 (en) 1999-12-02
WO1999061044A9 (en) 2000-02-10

Similar Documents

Publication Publication Date Title
HUP9904239A3 (en) High level expression of proteins
PL339463A1 (en) April - novel protein of growth promoting action
AU6024696A (en) Cartilage induction by bone morphogenetic proteins
AU9102898A (en) Pluripotential bone marrow cell line and methods of using the same
AU3866097A (en) Naphtholactams and lactones as bone morphogenetic protein active agents
AU7481098A (en) Osteoarthritis cartilage regeneration using human mesenchymal stem ce lls
AU6691798A (en) Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
AU1638097A (en) Novel inhibitors of bone reabsorption and antagonists of vitronectin receptors
AU7714898A (en) Bone morphogenetic proteins and their use in bone growth
AU9128798A (en) Genotyping of human cyp3a4
AU4989399A (en) Bone morphogenic protein
AU3359697A (en) Bone resorption inhibitors
AP2000001863A0 (en) Novel sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
AU5134599A (en) Expression of functional eukaryotic proteins
AU3549397A (en) Over-expression of proteins
AU8768298A (en) Chemical modification of proteins to improve biocompatibility and bioactivity
AU2375095A (en) Container made of ice
AU4409899A (en) Noggin and antagonists of bone morphogenetic proteins to suppress pathologic bone resorption
AU7115996A (en) Uses of bone morphogenetic proteins
AU5679198A (en) Lyophilized composition of bone morphogenetic factor human MP52
AU4073600A (en) Bone morphogenic proteins
AU5914299A (en) Antagonists of fibroblast growth factor
AU2241699A (en) Expression of proteolytically-sensitive peptides
AUPP385598A0 (en) Purification of antibodies
AU8265998A (en) Antibody to and assay for peptide linked-pyridinoline as indicator of bone resorption level

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase