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AU4342485A - Insulin preparation with thickening agent and surfactant - Google Patents

Insulin preparation with thickening agent and surfactant

Info

Publication number
AU4342485A
AU4342485A AU43424/85A AU4342485A AU4342485A AU 4342485 A AU4342485 A AU 4342485A AU 43424/85 A AU43424/85 A AU 43424/85A AU 4342485 A AU4342485 A AU 4342485A AU 4342485 A AU4342485 A AU 4342485A
Authority
AU
Australia
Prior art keywords
plunger pipe
plate
damper
sealing plate
pipe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU43424/85A
Other versions
AU575951B2 (en
Inventor
Ulrich Grau
Dietrich Hiller
Horst Paul Neubauer
Gerhard Ross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843443877 external-priority patent/DE3443877A1/en
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4342485A publication Critical patent/AU4342485A/en
Application granted granted Critical
Publication of AU575951B2 publication Critical patent/AU575951B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Prostheses (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

1. Pulsation damper (10) for elastically disposed objects (26), including a damper housing which is at least partially filled with 3 viscose damping medium (12) and which is open at the top relative to its installation position ; a hollow plunger pipe (17) which is open at the bottom relative to its installation position and continuously conically formed and which can be moved up and down into the damper medium (12) ; a top plate (16), linked with the plunger pipe (17), for receiving the object (26), in which respect the plunger pipe (17) is connected with the top plate (16) by its smaller diameter (28), and its larger diameter (29) is emersed into the damper medium (12), characterised in that the interior of the plunger pipe (17) is divided into two chambers by a sealing plate (22) ; that a buffer plate (24) including passages (33) is disposed in the larger diameter (29) at the bottom of the plunger pipe (17) which plate carries a plurality of interior pipes (21) which extend into the plunger pipe (17), the upper ends of the interior pipes (21) being at a distance (35) from the sealing plate (22), and the plunger pipe (17) has a plurality of peripheral bores (19) in the casing surface below the sealing plate (22).
AU43424/85A 1984-06-09 1985-06-07 Insulin preparation with thickening agent and surfactant Expired AU575951B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE3421615 1984-06-09
DE3421613 1984-06-09
DE3421615 1984-06-09
DE3421613 1984-06-09
DE19843443877 DE3443877A1 (en) 1984-06-09 1984-12-01 Insulin preparations, process for their preparation, and their use
DE3443877 1984-12-01

Publications (2)

Publication Number Publication Date
AU4342485A true AU4342485A (en) 1985-12-12
AU575951B2 AU575951B2 (en) 1988-08-11

Family

ID=27192050

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43424/85A Expired AU575951B2 (en) 1984-06-09 1985-06-07 Insulin preparation with thickening agent and surfactant

Country Status (16)

Country Link
EP (1) EP0166971B1 (en)
AT (1) ATE50502T1 (en)
AU (1) AU575951B2 (en)
CA (1) CA1258427A (en)
DE (1) DE3576120D1 (en)
DK (1) DK162255C (en)
ES (1) ES8605679A1 (en)
FI (1) FI80596C (en)
GR (1) GR851393B (en)
HU (1) HU200102B (en)
IE (1) IE57998B1 (en)
IL (1) IL75448A (en)
NO (1) NO164277C (en)
NZ (1) NZ212338A (en)
PH (1) PH24118A (en)
PT (1) PT80620B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU617157B2 (en) * 1988-03-11 1991-11-21 Teikoku Seiyaku Co., Ltd Intravaginal delivery of biologically active polypeptides
US7452860B2 (en) 2001-03-23 2008-11-18 Sanofi-Aventis Deutschland Gmbh Zinc-free and low-zinc insulin preparations having improved stability

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10227232A1 (en) * 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Sour insulin preparations with improved stability
KR101820024B1 (en) 2008-10-17 2018-01-18 사노피-아벤티스 도이칠란트 게엠베하 Combination of an insulin and a GLP-1 agonist
LT2498801T (en) 2009-11-13 2018-05-10 Sanofi-Aventis Deutschland Gmbh PHARMACEUTICAL COMPOSITION COMPRISING desPro36Exendin-4(1-39)-Lys6-NH2 AND METHIONINE
PL3417871T3 (en) 2009-11-13 2021-06-14 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a glp-1-agonist, an insulin, and methionine
MX339614B (en) 2010-08-30 2016-06-02 Sanofi - Aventis Deutschland GmbH Use of ave0010 for the manufacture of a medicament for the treatment of diabetes mellitus type 2.
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
CN110354255B (en) 2013-04-03 2024-05-14 赛诺菲 Treatment of diabetes by long acting insulin formulations
CA2970200A1 (en) 2014-12-12 2016-06-16 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (en) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 Treatment type 2 diabetes mellitus patients
TW201705975A (en) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 Treatment of type 2 diabetes mellitus patients

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2474729A (en) * 1945-01-03 1949-06-28 Rhone Poulenc Sa Insulin preparations
US2574889A (en) * 1947-10-06 1951-11-13 Leo Ab Methylated gelatin-insulin preparation
SU1011126A1 (en) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Method of treating diabetes mellitus
CH650677A5 (en) * 1981-08-27 1985-08-15 Lilly Co Eli AGAINST DIABETES MELLITUS ACTIVE PHARMACEUTICAL AGENT.
FI78616C (en) * 1982-02-05 1989-09-11 Novo Industri As Process for preparing an infused stabilized insulin solution having an elevated zinc content
AU4292585A (en) * 1984-04-30 1985-11-28 Trustees Of Columbia University In The City Of New York, The Topical treatment of diabetes with insulin and penetrant enhancer applied to the skin and covered by a patch

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU617157B2 (en) * 1988-03-11 1991-11-21 Teikoku Seiyaku Co., Ltd Intravaginal delivery of biologically active polypeptides
US7452860B2 (en) 2001-03-23 2008-11-18 Sanofi-Aventis Deutschland Gmbh Zinc-free and low-zinc insulin preparations having improved stability
US7696162B2 (en) 2001-03-23 2010-04-13 Sanofi-Aventis Deutschland Gmbh Zinc-free and low-zinc insulin preparations having improved stability

Also Published As

Publication number Publication date
DK162255C (en) 1992-03-16
NO164277B (en) 1990-06-11
IE57998B1 (en) 1993-06-02
FI852273A0 (en) 1985-06-06
PH24118A (en) 1990-03-05
PT80620B (en) 1987-10-20
CA1258427A (en) 1989-08-15
EP0166971B1 (en) 1990-02-28
ES543972A0 (en) 1986-01-16
DK254585D0 (en) 1985-06-06
NO852314L (en) 1985-12-10
IE851431L (en) 1985-12-09
DK254585A (en) 1985-12-10
FI80596B (en) 1990-03-30
NZ212338A (en) 1989-02-24
HUT37893A (en) 1986-03-28
PT80620A (en) 1985-07-01
ATE50502T1 (en) 1990-03-15
IL75448A0 (en) 1985-10-31
HU200102B (en) 1990-04-28
FI80596C (en) 1990-07-10
ES8605679A1 (en) 1986-01-16
GR851393B (en) 1985-11-25
NO164277C (en) 1990-09-19
DE3576120D1 (en) 1990-04-05
AU575951B2 (en) 1988-08-11
FI852273L (en) 1985-12-10
DK162255B (en) 1991-10-07
EP0166971A1 (en) 1986-01-08
IL75448A (en) 1989-07-31

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