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AU4227189A - Cyclopeptide derivatives, usable as selective inhibitors of proteases with active serine - Google Patents

Cyclopeptide derivatives, usable as selective inhibitors of proteases with active serine

Info

Publication number
AU4227189A
AU4227189A AU42271/89A AU4227189A AU4227189A AU 4227189 A AU4227189 A AU 4227189A AU 42271/89 A AU42271/89 A AU 42271/89A AU 4227189 A AU4227189 A AU 4227189A AU 4227189 A AU4227189 A AU 4227189A
Authority
AU
Australia
Prior art keywords
proteases
usable
selective inhibitors
active serine
cyclopeptide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU42271/89A
Other versions
AU626192B2 (en
Inventor
Jean-Paul Mazaleyrat
Michele Reboud
Michel Wakselman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of AU4227189A publication Critical patent/AU4227189A/en
Application granted granted Critical
Publication of AU626192B2 publication Critical patent/AU626192B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU42271/89A 1988-09-02 1989-08-31 Cyclopeptide derivatives, usable as selective inhibitors of proteases with active serine Ceased AU626192B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8811528 1988-09-02
FR8811528A FR2636066B1 (en) 1988-09-02 1988-09-02 CYCLOPEPTIDE DERIVATIVES FOR USE AS SELECTIVE INHIBITORS AGAINST ACTIVE SERINE PROTEASES

Publications (2)

Publication Number Publication Date
AU4227189A true AU4227189A (en) 1990-04-02
AU626192B2 AU626192B2 (en) 1992-07-23

Family

ID=9369677

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42271/89A Ceased AU626192B2 (en) 1988-09-02 1989-08-31 Cyclopeptide derivatives, usable as selective inhibitors of proteases with active serine

Country Status (8)

Country Link
US (1) US5138035A (en)
EP (1) EP0357510A1 (en)
JP (1) JPH03502102A (en)
AU (1) AU626192B2 (en)
DK (1) DK107790A (en)
FR (1) FR2636066B1 (en)
OA (1) OA09448A (en)
WO (1) WO1990002750A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2636066B1 (en) * 1988-09-02 1991-10-25 Centre Nat Rech Scient CYCLOPEPTIDE DERIVATIVES FOR USE AS SELECTIVE INHIBITORS AGAINST ACTIVE SERINE PROTEASES
WO1992002822A1 (en) * 1990-08-06 1992-02-20 Cetus Corporation Methods for the identification of cytokine convertase inhibitors
US5635477A (en) * 1991-09-30 1997-06-03 The Dupont Merck Pharmaceutical Company Cyclic compounds useful as inhibitors of platelet glycoprotein IIB/IIIA
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
AU6415894A (en) * 1993-03-29 1994-10-24 Du Pont Merck Pharmaceutical Company, The Cyclic compounds useful as inhibitors of platelet glycoprotein iib/iiia
JPH08509708A (en) * 1993-03-29 1996-10-15 ザ・デュポン・メルク・ファーマシュウティカル・カンパニー Novel method and intermediate compound for preparation of platelet glycoprotein IIb / IIIa inhibitor
US5516889A (en) * 1993-06-21 1996-05-14 University Technologies International, Inc. Synthetic thrombin receptor peptides
EP0815870A3 (en) * 1996-06-27 2000-05-03 Takeda Chemical Industries, Ltd. Composition for prohylaxis or treatment of cerebral infarction
DE19942624A1 (en) * 1999-08-28 2001-03-08 Chemotopix Gmbh Process for the preparation of cyclic peptidomimetics

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2636066B1 (en) * 1988-09-02 1991-10-25 Centre Nat Rech Scient CYCLOPEPTIDE DERIVATIVES FOR USE AS SELECTIVE INHIBITORS AGAINST ACTIVE SERINE PROTEASES

Also Published As

Publication number Publication date
DK107790A (en) 1990-07-02
US5138035A (en) 1992-08-11
WO1990002750A1 (en) 1990-03-22
FR2636066A1 (en) 1990-03-09
OA09448A (en) 1992-10-15
JPH03502102A (en) 1991-05-16
AU626192B2 (en) 1992-07-23
EP0357510A1 (en) 1990-03-07
DK107790D0 (en) 1990-05-01
FR2636066B1 (en) 1991-10-25

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