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AU3910000A - Improved methods for producing proteins in transformed (pichia) - Google Patents

Improved methods for producing proteins in transformed (pichia)

Info

Publication number
AU3910000A
AU3910000A AU39100/00A AU3910000A AU3910000A AU 3910000 A AU3910000 A AU 3910000A AU 39100/00 A AU39100/00 A AU 39100/00A AU 3910000 A AU3910000 A AU 3910000A AU 3910000 A AU3910000 A AU 3910000A
Authority
AU
Australia
Prior art keywords
pichia
transformed
improved methods
producing proteins
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU39100/00A
Inventor
Bruce L. Zamost
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU3910000A publication Critical patent/AU3910000A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU39100/00A 1999-03-22 2000-03-21 Improved methods for producing proteins in transformed (pichia) Abandoned AU3910000A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27426399A 1999-03-22 1999-03-22
US09274263 1999-03-22
PCT/US2000/007618 WO2000056903A2 (en) 1999-03-22 2000-03-21 IMPROVED METHODS FOR PRODUCING PROTEINS IN TRANSFORMED $i(PICHIA)

Publications (1)

Publication Number Publication Date
AU3910000A true AU3910000A (en) 2000-10-09

Family

ID=23047491

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39100/00A Abandoned AU3910000A (en) 1999-03-22 2000-03-21 Improved methods for producing proteins in transformed (pichia)

Country Status (2)

Country Link
AU (1) AU3910000A (en)
WO (1) WO2000056903A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348331B1 (en) 1999-09-08 2002-02-19 Zymogenetics, Inc. Pichia methanolica glyceraldehyde-3-phosphate dehydrogenase 2 promoter
JP2003509024A (en) * 1999-09-08 2003-03-11 ザイモジェネティクス，インコーポレイティド Pichia methanolica glyceraldehyde-3-phosphate dehydrogenase 2 promoter and terminator
ATE494367T1 (en) 2002-12-18 2011-01-15 Hoffmann La Roche RECOMBINANT DESOXYRIBONUCLEASE I FROM BOvine PANCREASE WITH HIGH SPECIFIC ACTIVITY
EP1460425A1 (en) 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
AT501955B1 (en) * 2005-02-23 2007-08-15 Univ Graz Tech MUTED AOX1 PROMOTERS
ES2370657T3 (en) 2005-09-14 2011-12-21 Sanofi-Aventis Deutschland Gmbh EXCISION OF INSULIN PRECURSORS THROUGH A VARIANT OF TRIPSINE.
EP2106447B1 (en) 2007-01-26 2013-04-17 Novozymes A/S Method for methanol independent induction from methanol inducible promoters in pichia
MX349413B (en) 2008-02-06 2017-07-19 Biocon Ltd Fermentation media comprising urea-like nitrogen sources and its use for the production of secondary metabolits, enzymes and recombinant proteias.
EP2494050A4 (en) * 2009-10-30 2013-10-30 Merck Sharp & Dohme FACTOR FOR STIMULATING GRANULOCYTES AND MONOCYTES PRODUCED IN GLYCOMODIFIED PICHIA PASTORIS
US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
AU2016273912B2 (en) * 2011-05-20 2018-08-02 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
EP2710114B1 (en) * 2011-05-20 2021-11-03 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as pichia pastoris
US10150968B2 (en) 2011-08-19 2018-12-11 Alderbio Holdings Llc Multi-copy strategy for high-titer and high-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
DK3184642T3 (en) * 2015-12-22 2019-08-12 Bisy E U yeast
CN114686487B (en) * 2021-11-08 2023-12-22 泰州博莱得利生物科技有限公司 Efficient expression method of cat and dog interleukin 11 (IL-11) in pichia pastoris and application thereof
CN116103174B (en) * 2022-07-20 2024-11-29 青岛蔚蓝生物集团有限公司 A mutant strain of Pichia pastoris and its application in lysozyme production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0436625A4 (en) * 1988-09-26 1991-08-21 The Salk Institute Biotechnology Industrial Associates, Inc. Mixed feed recombinant yeast fermentation
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
GB9402832D0 (en) * 1994-02-15 1994-04-06 Smith Kline Beecham Biolog S A Novel process
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
US5854039A (en) * 1996-07-17 1998-12-29 Zymogenetics, Inc. Transformation of pichia methanolica
AU718510B2 (en) * 1996-07-17 2000-04-13 Zymogenetics Inc. Transformation of pichia methanolica

Also Published As

Publication number Publication date
WO2000056903A3 (en) 2000-12-28
WO2000056903A2 (en) 2000-09-28

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase