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AU3254693A - Process for the manufacture of soft gelatin capsules by a drip-feed method - Google Patents

Process for the manufacture of soft gelatin capsules by a drip-feed method

Info

Publication number
AU3254693A
AU3254693A AU32546/93A AU3254693A AU3254693A AU 3254693 A AU3254693 A AU 3254693A AU 32546/93 A AU32546/93 A AU 32546/93A AU 3254693 A AU3254693 A AU 3254693A AU 3254693 A AU3254693 A AU 3254693A
Authority
AU
Australia
Prior art keywords
soft gelatin
drip
manufacture
feed method
gelatin capsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU32546/93A
Other versions
AU670771B2 (en
Inventor
Jurgen Freidenreich
Ursula Schick
Jurgen Werry
Jens-Christian Wunderlich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfatec Pharma GmbH
Original Assignee
Alfatec Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4201178A external-priority patent/DE4201178C2/en
Application filed by Alfatec Pharma GmbH filed Critical Alfatec Pharma GmbH
Publication of AU3254693A publication Critical patent/AU3254693A/en
Application granted granted Critical
Publication of AU670771B2 publication Critical patent/AU670771B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention concerns a drip-feed method for the manufacture of soft gelatin capsules, the preferably soft or liquid contents being enclosed in soft gelatin which is then solidified in a low-temperature cooling bath containing a chemically inert liquified gas which leaves no biologically undesirable or toxic residues on the capsules. Liquid nitrogen is preferably used as the cooling-bath liquid.
AU32546/93A 1992-01-17 1993-01-18 Process for the manufacture of soft gelatin capsules by a drip-feed method Ceased AU670771B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE4201178 1992-01-17
DE4201178A DE4201178C2 (en) 1992-01-17 1992-01-17 Process for the production of soft gelatin capsules by a dropping process
US07/876,863 US5254294A (en) 1992-01-17 1992-04-30 Soft gelatin capsules
US876863 1992-04-30
PCT/DE1993/000035 WO1993013761A1 (en) 1992-01-17 1993-01-18 Process for the manufacture of soft gelatin capsules by a drip-feed method

Publications (2)

Publication Number Publication Date
AU3254693A true AU3254693A (en) 1993-08-03
AU670771B2 AU670771B2 (en) 1996-08-01

Family

ID=25911045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32546/93A Ceased AU670771B2 (en) 1992-01-17 1993-01-18 Process for the manufacture of soft gelatin capsules by a drip-feed method

Country Status (10)

Country Link
EP (1) EP0623018B1 (en)
JP (1) JPH07502912A (en)
AT (1) ATE132036T1 (en)
AU (1) AU670771B2 (en)
CA (1) CA2128243C (en)
DE (1) DE59301262D1 (en)
DK (1) DK0623018T3 (en)
ES (1) ES2083846T3 (en)
GR (1) GR3019424T3 (en)
WO (1) WO1993013761A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE181666T1 (en) 1992-01-17 1999-07-15 Alfatec Pharma Gmbh METHOD FOR PRODUCING POWDERS, GRANULES OR PELLETS CONTAINING ACTIVE INGREDIENTS WITH A FRAMEWORK OF HYDROPHILIC MACROMOLECLES AND THE USE THEREOF
AU7904598A (en) * 1997-07-09 1999-02-08 Peter Greither Method and device for producing a multi-layer, physiologically tolerated presentation form
DE19930030B4 (en) * 1999-06-30 2004-02-19 Meduna Arzneimittel Gmbh Oral dosage form containing CO-3-unsaturated fatty acids
US7264824B1 (en) 2000-04-13 2007-09-04 Meduna Arzneimittel Gmbh Oral dosage form
JP5876695B2 (en) * 2011-09-29 2016-03-02 森下仁丹株式会社 Seamless capsule and method for producing the same
JP5989953B1 (en) * 2015-12-28 2016-09-07 森下仁丹株式会社 Seamless capsule containing powdery component and method for producing the same
CN110090599B (en) * 2019-05-20 2024-09-17 武汉大坦智能装备科技有限公司 Multi-station pill dropping machine
DE102021107251A1 (en) 2021-03-23 2022-09-29 Technische Universität Dortmund Process for coating particles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1080822A (en) * 1952-05-26 1954-12-14 Trifax N V Chemisch Pharmaceut Method and device for the production of seamless capsules
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives
HUT75670A (en) * 1993-06-18 1997-05-28 Smithkline Beecham Corp Soft-shelled gelatin encapsulated particles and process for its production
EP0649651B1 (en) * 1993-09-28 2000-12-13 R.P. Scherer GmbH Soft gelatin capsule manufacture

Also Published As

Publication number Publication date
WO1993013761A1 (en) 1993-07-22
DE59301262D1 (en) 1996-02-08
CA2128243C (en) 1998-09-22
ES2083846T3 (en) 1996-04-16
DK0623018T3 (en) 1996-03-04
EP0623018A1 (en) 1994-11-09
JPH07502912A (en) 1995-03-30
CA2128243A1 (en) 1993-07-22
ATE132036T1 (en) 1996-01-15
EP0623018B1 (en) 1995-12-27
GR3019424T3 (en) 1996-06-30
AU670771B2 (en) 1996-08-01

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired