AU2388800A - Stable subtilin and methods of manufacture - Google Patents
Stable subtilin and methods of manufactureInfo
- Publication number
- AU2388800A AU2388800A AU23888/00A AU2388800A AU2388800A AU 2388800 A AU2388800 A AU 2388800A AU 23888/00 A AU23888/00 A AU 23888/00A AU 2388800 A AU2388800 A AU 2388800A AU 2388800 A AU2388800 A AU 2388800A
- Authority
- AU
- Australia
- Prior art keywords
- subtilin
- manufacture
- stable
- methods
- stable subtilin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- RKLXDNHNLPUQRB-TVJUEJKUSA-N chembl564271 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]2C(C)SC[C@H](N[C@@H](CC(N)=O)C(=O)NC(=O)[C@@H](NC2=O)CSC1C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(=C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H]1NC(=O)C(=C\C)/NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@H]3N[C@@H](CC(C)C)C(=O)NC(=O)C(=C)NC(=O)CC[C@H](NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=4C5=CC=CC=C5NC=4)CSC3)C(O)=O)C(C)SC2)C(C)C)C(C)SC1)C1=CC=CC=C1 RKLXDNHNLPUQRB-TVJUEJKUSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108010082567 subtilin Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/7295—Antibiotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11384398P | 1998-12-24 | 1998-12-24 | |
| US60113843 | 1998-12-24 | ||
| PCT/US1999/030938 WO2000039152A1 (en) | 1998-12-24 | 1999-12-23 | Stable subtilin and methods of manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2388800A true AU2388800A (en) | 2000-07-31 |
Family
ID=22351844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU23888/00A Abandoned AU2388800A (en) | 1998-12-24 | 1999-12-23 | Stable subtilin and methods of manufacture |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1140975A4 (en) |
| AU (1) | AU2388800A (en) |
| CA (1) | CA2356955A1 (en) |
| WO (1) | WO2000039152A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6953683B2 (en) | 1997-07-18 | 2005-10-11 | University Of Maryland | Compositions and methods of inhibiting bacterial spore germination |
| US6541607B1 (en) | 1997-07-18 | 2003-04-01 | University Of Maryland | Sublancin lantibiotic produced by Bacillus subtilis 168 |
| US6846804B2 (en) | 2000-06-29 | 2005-01-25 | University Of Maryland, College Park Office Of Technology Commercialization | Construction of a structural variant of sublancin to facilitate its isolation and use in bioremediation of environmental contamination by gram-positive spore formers such as bacillus anthrasis |
| US6759205B2 (en) | 2000-06-29 | 2004-07-06 | University Of Maryland | Construction of a strain of Bacillus subtilis 168 that displays the sublancin lantibiotic on the surface of the cell |
| US7033766B2 (en) | 2000-06-29 | 2006-04-25 | University Of Maryland Office Of Technology Commercialization | Construction and screening of lantibody display libraries |
| CN101776665B (en) * | 2009-01-13 | 2013-09-11 | 上海医药工业研究院 | HPLC detection method of nisin |
| EP3935067A4 (en) * | 2019-03-08 | 2022-12-07 | Fraunhofer USA, Inc. | Novel antimicrobial lantibiotic peptide and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516682A (en) * | 1988-07-05 | 1996-05-14 | University Of Maryland | Subtilin variant of enhanced stability and activity |
| US5218101A (en) * | 1988-07-05 | 1993-06-08 | The University Of Maryland | Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor |
| US5861275A (en) * | 1995-09-28 | 1999-01-19 | The University Of Maryland | Lantibiotic mutants and chimeras of enhanced stability and activity, leader sequences therefor, genes encoding the same, and methods of producing and using the same |
-
1999
- 1999-12-23 EP EP99967636A patent/EP1140975A4/en not_active Withdrawn
- 1999-12-23 AU AU23888/00A patent/AU2388800A/en not_active Abandoned
- 1999-12-23 WO PCT/US1999/030938 patent/WO2000039152A1/en not_active Application Discontinuation
- 1999-12-23 CA CA002356955A patent/CA2356955A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1140975A1 (en) | 2001-10-10 |
| CA2356955A1 (en) | 2000-07-06 |
| EP1140975A4 (en) | 2003-01-08 |
| WO2000039152A1 (en) | 2000-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |