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AU2143292A - Peptidomimetic inhibitors of hiv gp120 binding to cd4 - Google Patents

Peptidomimetic inhibitors of hiv gp120 binding to cd4

Info

Publication number
AU2143292A
AU2143292A AU21432/92A AU2143292A AU2143292A AU 2143292 A AU2143292 A AU 2143292A AU 21432/92 A AU21432/92 A AU 21432/92A AU 2143292 A AU2143292 A AU 2143292A AU 2143292 A AU2143292 A AU 2143292A
Authority
AU
Australia
Prior art keywords
hiv
binding
peptidomimetic inhibitors
peptidomimetic
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU21432/92A
Inventor
Mark I. Greene
Michael Kahn
Apichaya Raktabutr
Horacio U Saragovi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois System
Original Assignee
University of Illinois at Urbana Champaign
University of Illinois System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois at Urbana Champaign, University of Illinois System filed Critical University of Illinois at Urbana Champaign
Publication of AU2143292A publication Critical patent/AU2143292A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU21432/92A 1991-05-21 1992-05-19 Peptidomimetic inhibitors of hiv gp120 binding to cd4 Abandoned AU2143292A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70346591A 1991-05-21 1991-05-21
US703465 1991-05-21

Publications (1)

Publication Number Publication Date
AU2143292A true AU2143292A (en) 1992-12-30

Family

ID=24825498

Family Applications (1)

Application Number Title Priority Date Filing Date
AU21432/92A Abandoned AU2143292A (en) 1991-05-21 1992-05-19 Peptidomimetic inhibitors of hiv gp120 binding to cd4

Country Status (2)

Country Link
AU (1) AU2143292A (en)
WO (1) WO1992020704A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5475085A (en) * 1991-02-07 1995-12-12 Molecumetics, Ltd. Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
AU1570292A (en) * 1991-02-07 1992-09-07 Board Of Trustees Of The University Of Illinois, The Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
AU4396693A (en) * 1992-05-28 1993-12-30 Board Of Trustees Of The University Of Illinois, The Design and synthesis of a CD4 beta-turn mimetic for inhibiting the binding of HIV GP120
EP0656907A1 (en) * 1992-08-06 1995-06-14 Molecumetics, Ltd. Conformationally restricted mimetics of reverse turns and peptides containing the same
US5693325A (en) * 1994-03-15 1997-12-02 Molecumetics, Ltd. Peptide vaccines and methods relating thereto
US7345020B2 (en) * 1995-06-29 2008-03-18 Thomas Jefferson University Mimetics of CD4 that inhibit immune response

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5656890A (en) * 1989-05-02 1990-11-29 Genelabs Incorporated Chemically modified cd4 peptide fragments having anti-retroviral properties

Also Published As

Publication number Publication date
WO1992020704A1 (en) 1992-11-26

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