AU2068599A - Polypeptides, dna coding therefor, formulations thereof, and their use in inhibiting factor xii activation - Google Patents
Polypeptides, dna coding therefor, formulations thereof, and their use in inhibiting factor xii activationInfo
- Publication number
- AU2068599A AU2068599A AU20685/99A AU2068599A AU2068599A AU 2068599 A AU2068599 A AU 2068599A AU 20685/99 A AU20685/99 A AU 20685/99A AU 2068599 A AU2068599 A AU 2068599A AU 2068599 A AU2068599 A AU 2068599A
- Authority
- AU
- Australia
- Prior art keywords
- polypeptides
- formulations
- dna coding
- factor xii
- inhibiting factor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9800817 | 1998-01-16 | ||
GBGB9800817.0A GB9800817D0 (en) | 1998-01-16 | 1998-01-16 | Serine protease inhibitors |
PCT/GB1999/000147 WO1999036439A1 (en) | 1998-01-16 | 1999-01-15 | Polypeptides, dna coding therefor, formulations thereof, and their use in inhibiting factor xii activation |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2068599A true AU2068599A (en) | 1999-08-02 |
Family
ID=10825322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU20685/99A Abandoned AU2068599A (en) | 1998-01-16 | 1999-01-15 | Polypeptides, dna coding therefor, formulations thereof, and their use in inhibiting factor xii activation |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1045862A1 (en) |
JP (1) | JP2002508953A (en) |
AU (1) | AU2068599A (en) |
CA (1) | CA2318358A1 (en) |
GB (1) | GB9800817D0 (en) |
WO (1) | WO1999036439A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9930659D0 (en) * | 1999-12-24 | 2000-02-16 | Bio Discovery Ltd | Inhibitors of complement activation |
AU2001282857A1 (en) * | 2000-06-21 | 2002-01-02 | Zymogenetics Inc. | Peptide and polypeptide inhibitors of complement c1s |
CN1373218A (en) * | 2001-02-28 | 2002-10-09 | 中国医学科学院阜外心血管病医院 | Inflammatory suppressor factor Fwa 116 |
WO2006066878A1 (en) | 2004-12-23 | 2006-06-29 | Csl Behring Gmbh | Prevention of thrombus formation and/or stabilization |
KR101954052B1 (en) * | 2011-03-09 | 2019-03-06 | 체에스엘 베링 게엠베하 | Factor xii inhibitors for the administration with medical procedures comprising contact with artificial surfaces |
EP2497489A1 (en) | 2011-03-09 | 2012-09-12 | CSL Behring GmbH | Factor XII inhibitors for the treatment of silent brain ischemia and ischemia of other organs |
EP2623110A1 (en) * | 2012-01-31 | 2013-08-07 | CSL Behring GmbH | Factor XII inhibitors for the treatment of neurological inflammatory disorders |
WO2014135694A1 (en) | 2013-03-08 | 2014-09-12 | Csl Behring Ag | Treatment and prevention of remote ischemia-reperfusion injury |
JP2017501968A (en) * | 2013-06-28 | 2017-01-19 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | Combination therapy using factor XII inhibitor and C1-inhibitor |
WO2015054569A1 (en) * | 2013-10-10 | 2015-04-16 | Viropharma Holdings Limited | Methods of inhibiting the alternative pathway of complement immune system activation and compositions used therein |
US11505619B2 (en) | 2017-12-15 | 2022-11-22 | Csl Limited | Use of a FXIIa-inhibitor in the treatment of renal fibrosis and/or chronic kidney disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0333356A3 (en) * | 1988-03-04 | 1990-12-19 | Biogen, Inc. | Hirudin peptides |
EP0719334A1 (en) * | 1993-09-14 | 1996-07-03 | Genentech, Inc. | Pharmaceutical compositions containing ecotin and homologs thereof |
US5866402A (en) * | 1995-05-05 | 1999-02-02 | Chiron Corporation | Chimeric MCP and DAF proteins with cell surface localizing domain |
-
1998
- 1998-01-16 GB GBGB9800817.0A patent/GB9800817D0/en not_active Ceased
-
1999
- 1999-01-15 CA CA002318358A patent/CA2318358A1/en not_active Abandoned
- 1999-01-15 JP JP2000540154A patent/JP2002508953A/en active Pending
- 1999-01-15 AU AU20685/99A patent/AU2068599A/en not_active Abandoned
- 1999-01-15 EP EP99901059A patent/EP1045862A1/en not_active Withdrawn
- 1999-01-15 WO PCT/GB1999/000147 patent/WO1999036439A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2002508953A (en) | 2002-03-26 |
CA2318358A1 (en) | 1999-07-22 |
WO1999036439A1 (en) | 1999-07-22 |
EP1045862A1 (en) | 2000-10-25 |
GB9800817D0 (en) | 1998-03-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |