AU2003253971A1 - Polymorphic forms of nateglinide - Google Patents

Polymorphic forms of nateglinide

Info

Publication number: AU2003253971A1
Authority: AU; Australia
Prior art keywords: nateglinide; polymorphic forms; polymorphic; forms
Prior art date: 2002-07-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2003253971A

Inventor

Ben-Zion Dolitzky

Boaz Gome

Yigael Gozlan

Evgeny Shapiro

Ronit Yahalomi

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Teva Pharmaceutical Industries Ltd

Original Assignee

Teva Pharmaceutical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-18

Filing date

2003-07-18

Publication date

2004-02-09

2003-07-03 Priority claimed from US10/614,266 external-priority patent/US6861553B2/en

2003-07-18 Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd

2004-02-09 Publication of AU2003253971A1 publication Critical patent/AU2003253971A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Obesity (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AU2003253971A 2002-07-18 2003-07-18 Polymorphic forms of nateglinide Abandoned AU2003253971A1 (en)

Applications Claiming Priority (21)

Application Number	Priority Date	Filing Date	Title
US39690402P	2002-07-18	2002-07-18
US60/396,904		2002-07-18
US41362202P	2002-09-25	2002-09-25
US60/413,622		2002-09-25
US41419902P	2002-09-26	2002-09-26
US60/414,199		2002-09-26
US42375002P	2002-11-05	2002-11-05
US60/423,750		2002-11-05
US43209302P	2002-12-10	2002-12-10
US60/432,093		2002-12-10
US43296202P	2002-12-12	2002-12-12
US60/432,962		2002-12-12
US44210903P	2003-01-23	2003-01-23
US60/442,109		2003-01-23
US44979103P	2003-02-24	2003-02-24
US60/449,791		2003-02-24
US47901603P	2003-06-16	2003-06-16
US60/479,016		2003-06-16
US10/614,266		2003-07-03
US10/614,266 US6861553B2 (en)	2002-07-03	2003-07-03	Process for preparing nateglinide and intermediates thereof
PCT/US2003/022375 WO2004009532A1 (en)	2002-07-18	2003-07-18	Polymorphic forms of nateglinide

Publications (1)

Publication Number	Publication Date
AU2003253971A1 true AU2003253971A1 (en)	2004-02-09

Family

ID=30773824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2003253971A Abandoned AU2003253971A1 (en)	2002-07-18	2003-07-18	Polymorphic forms of nateglinide

Country Status (6)

Country	Link
EP (1)	EP1467964A1 (en)
JP (1)	JP2006511614A (en)
AU (1)	AU2003253971A1 (en)
CA (1)	CA2492644A1 (en)
IL (1)	IL166308A0 (en)
WO (1)	WO2004009532A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7534913B2 (en) *	2002-07-18	2009-05-19	Teva Pharmaceutica Industries Ltd.	Crystalline form of nateglinide
HU227073B1 (en) *	2003-07-10	2010-06-28	Richter Gedeon Nyrt	Process for the preparation of chirally pure n-(trans-4-isopropyl-cyclohexylcarbonyl)-d-phenyl-alanine (nateglinide) and it's crystalline forms and the cristalline form g
US20060004102A1 (en) *	2004-05-07	2006-01-05	Shlomit Wizel	Polymorphic forms of nateglinide
CA2625299A1 (en) *	2005-11-22	2007-05-31	Teva Pharmaceutical Industries Ltd.	Crystal forms of cinacalcet hci and processes for their preparation
CN105916502A (en)	2013-11-15	2016-08-31	阿克比治疗有限公司	Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
CN109369443A (en) *	2018-11-05	2019-02-22	扬子江药业集团江苏海慈生物药业有限公司	A kind of preparation method of new Nateglinide H crystal form

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6354321A (en) *	1985-03-27	1988-03-08	Ajinomoto Co Inc	Blood sugar lowering agent
US5463116A (en) *	1991-07-30	1995-10-31	Ajinomoto Co., Inc.	Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
MXPA03003484A (en) *	2000-10-18	2003-07-14	Ajinomoto Kk	Process for producing nateglinide crystal.
DK1334964T3 (en) *	2000-10-24	2007-09-24	Ajinomoto Kk	Process for the preparation of B-form nateglinide crystals
EP1435912A4 (en) *	2001-09-12	2005-03-30	Alembic Ltd	Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation
EP2261202A1 (en) *	2002-04-15	2010-12-15	Ajinomoto Co., Inc.	New nateglinide crystals

2003
- 2003-07-18 WO PCT/US2003/022375 patent/WO2004009532A1/en active Application Filing
- 2003-07-18 JP JP2005505521A patent/JP2006511614A/en active Pending
- 2003-07-18 IL IL16630803A patent/IL166308A0/en unknown
- 2003-07-18 CA CA002492644A patent/CA2492644A1/en not_active Abandoned
- 2003-07-18 AU AU2003253971A patent/AU2003253971A1/en not_active Abandoned
- 2003-07-18 EP EP03765665A patent/EP1467964A1/en not_active Withdrawn

Also Published As

Publication number	Publication date
EP1467964A1 (en)	2004-10-20
WO2004009532A1 (en)	2004-01-29
CA2492644A1 (en)	2004-01-29
IL166308A0 (en)	2006-01-15
JP2006511614A (en)	2006-04-06

Publication	Publication Date	Title
AU2003202924A1 (en)	2003-07-30	Variation of neural-stimulation parameters
IL209966A0 (en)	2011-07-31	Modafinil polymorphic forms
AU2003205950A1 (en)	2003-09-02	Placement of alternative advertisements
AU2003236991A1 (en)	2003-12-19	Representations of processes
AU2003214112A1 (en)	2003-09-22	Salts of nateglinide
AU2003245572A1 (en)	2004-01-19	Preparation of chiral amino-nitriles
AU2003277596A1 (en)	2004-07-29	Method of deuterization
AU2003268687A1 (en)	2004-04-19	Novel salt of 2-acylaminothiazole derivative
AU2003251051A1 (en)	2004-03-03	Mounting of tubes
AU2003236243A1 (en)	2003-10-27	Novel nateglinide crystal
AU2003276026A1 (en)	2004-04-19	Bicalutamide forms
AUPS096002A0 (en)	2002-03-28	Method of construction
AU2003253971A1 (en)	2004-02-09	Polymorphic forms of nateglinide
AU2003216848A1 (en)	2003-10-08	Deracemisation of amines
AU2003229459A1 (en)	2003-12-02	Methods of using thiazolidinedithione derivatives
AU2003298725A1 (en)	2004-06-23	Preparation of metallotexaphyrins
AU2003238034A1 (en)	2004-01-23	Novel use of imidazotriazinones
AU2003235231A1 (en)	2003-12-19	Method of synthesizing cf3-chf-cf2-nr2
AU2003276825A1 (en)	2004-01-23	Method of immunotherapy
AU2003255130A1 (en)	2004-03-19	Inclusion compound of nateglinide
AU2003290512A1 (en)	2005-04-14	Method of weldbonding
AU2003240450A1 (en)	2003-11-10	Manufacture of ketopantolactone
AU2003217354A1 (en)	2003-09-02	Synthesis of sulfamidates
AU2003292255A1 (en)	2004-07-09	Polymorph
AU2002355031A1 (en)	2004-06-18	Method of synthesizing macrosphelides

Legal Events

Date	Code	Title	Description
2005-04-28	MK6	Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase