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AU2003250831A1 - Use of hec1 antagonists in the treatment of proliferative disorders and cancer - Google Patents

Use of hec1 antagonists in the treatment of proliferative disorders and cancer

Info

Publication number
AU2003250831A1
AU2003250831A1 AU2003250831A AU2003250831A AU2003250831A1 AU 2003250831 A1 AU2003250831 A1 AU 2003250831A1 AU 2003250831 A AU2003250831 A AU 2003250831A AU 2003250831 A AU2003250831 A AU 2003250831A AU 2003250831 A1 AU2003250831 A1 AU 2003250831A1
Authority
AU
Australia
Prior art keywords
hec1
antagonists
cancer
treatment
proliferative disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003250831A
Other versions
AU2003250831A8 (en
Inventor
Silvia Martin-Lluesma
Erich A. Nigg
Volker Stucke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften
Publication of AU2003250831A1 publication Critical patent/AU2003250831A1/en
Publication of AU2003250831A8 publication Critical patent/AU2003250831A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003250831A 2002-06-12 2003-06-12 Use of hec1 antagonists in the treatment of proliferative disorders and cancer Abandoned AU2003250831A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02013006 2002-06-12
EP02013006.8 2002-06-12
PCT/EP2003/006205 WO2003105891A2 (en) 2002-06-12 2003-06-12 Use of hec1 antagonists in the treatment of proliferative disorders and cancer

Publications (2)

Publication Number Publication Date
AU2003250831A1 true AU2003250831A1 (en) 2003-12-31
AU2003250831A8 AU2003250831A8 (en) 2003-12-31

Family

ID=29724387

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003250831A Abandoned AU2003250831A1 (en) 2002-06-12 2003-06-12 Use of hec1 antagonists in the treatment of proliferative disorders and cancer

Country Status (3)

Country Link
EP (1) EP1519736A2 (en)
AU (1) AU2003250831A1 (en)
WO (1) WO2003105891A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4761389B2 (en) 2004-04-09 2011-08-31 株式会社ジーンケア研究所 Cancer cell-specific apoptosis inducer targeting genes related to chromosome stabilization
JO3000B1 (en) 2004-10-20 2016-09-05 Genentech Inc Antibody Formulations.
WO2007075206A2 (en) * 2005-09-30 2007-07-05 The Regents Of The University Of California Satb1: a determinant of morphogenesis and tumor metastatis
RU2486195C2 (en) 2007-08-20 2013-06-27 Онкотерапи Сайенс, Инк. Cdca1 peptide and pharmaceutical drug containing it
TWI526219B (en) 2008-06-19 2016-03-21 腫瘤療法 科學股份有限公司 Cdca1 epitope peptides and vaccines containing the same
BR112012023355A2 (en) 2010-03-17 2016-05-31 Taivex Therapeutics Inc compound, pharmaceutical composition and method of disruption of nek2 / hec1 interaction
US11071736B2 (en) 2011-11-21 2021-07-27 Taivex Therapeutics Corporation Modulators of HEC1 activity and methods therefor
US9976183B2 (en) * 2011-11-21 2018-05-22 Taivex Therapeutics Corporation Biomarkers for cancers responsive to modulators of HEC1 activity
TWI640519B (en) 2011-11-29 2018-11-11 泰緯生命科技股份有限公司 Modulators of hec1 activity and methods therefor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6795898A (en) * 1997-04-04 1998-10-30 Board Of Regents, The University Of Texas System Proteins and compositions for modulating mitosis

Also Published As

Publication number Publication date
EP1519736A2 (en) 2005-04-06
WO2003105891A3 (en) 2004-05-06
AU2003250831A8 (en) 2003-12-31
WO2003105891A2 (en) 2003-12-24

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase