[go: up one dir, main page]

AU2003218629A1 - A building block forming a c-c or a c-hetero atom bond uponreaction - Google Patents

A building block forming a c-c or a c-hetero atom bond uponreaction

Info

Publication number
AU2003218629A1
AU2003218629A1 AU2003218629A AU2003218629A AU2003218629A1 AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1 AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A AU2003218629 A AU 2003218629A AU 2003218629 A1 AU2003218629 A1 AU 2003218629A1
Authority
AU
Australia
Prior art keywords
uponreaction
building block
hetero atom
block forming
atom bond
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003218629A
Inventor
Jakob Felding
Michael Anders Godskesen
Alex Haahr Gouliaev
Kim Birkebaerd Jensen
Mikkel Dybro Lundorf
Henrik Pedersen
Christian Sams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuevolution AS
Original Assignee
Nuevolution AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution AS filed Critical Nuevolution AS
Publication of AU2003218629A1 publication Critical patent/AU2003218629A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2003218629A 2002-03-15 2003-03-14 A building block forming a c-c or a c-hetero atom bond uponreaction Abandoned AU2003218629A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US36405602P 2002-03-15 2002-03-15
DKPA20020415 2002-03-15
DKPA200200415 2002-03-15
US60/364,056 2002-03-15
US43442302P 2002-12-19 2002-12-19
DKPA200201950 2002-12-19
US60/434,423 2002-12-19
DKPA200201950 2002-12-19
PCT/DK2003/000176 WO2003078446A2 (en) 2002-03-15 2003-03-14 A building block forming a c-c or a c-hetero atom bond upon reaction

Publications (1)

Publication Number Publication Date
AU2003218629A1 true AU2003218629A1 (en) 2003-09-29

Family

ID=28046589

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003218629A Abandoned AU2003218629A1 (en) 2002-03-15 2003-03-14 A building block forming a c-c or a c-hetero atom bond uponreaction

Country Status (4)

Country Link
US (1) US20050247001A1 (en)
EP (1) EP1487850A2 (en)
AU (1) AU2003218629A1 (en)
WO (1) WO2003078446A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1832567A3 (en) 2001-03-19 2009-08-26 President And Fellows Of Harvard College Evolving new molecular function
WO2002102820A1 (en) 2001-06-20 2002-12-27 Nuevolution A/S Nucleoside derivatives for library preparation
EP1487978B1 (en) 2002-03-15 2008-11-19 Nuevolution A/S An improved method for synthesising templated molecules
US10730906B2 (en) 2002-08-01 2020-08-04 Nuevolutions A/S Multi-step synthesis of templated molecules
US7491494B2 (en) 2002-08-19 2009-02-17 President And Fellows Of Harvard College Evolving new molecular function
EP2348124B1 (en) 2002-10-30 2013-12-11 Nuevolution A/S Synthesis of a bifunctional complex
US9121110B2 (en) 2002-12-19 2015-09-01 Nuevolution A/S Quasirandom structure and function guided synthesis methods
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
EP2236606B1 (en) 2003-03-20 2013-11-06 Nuevolution A/S Ligational encoding of small molecules
WO2005026387A1 (en) 2003-09-18 2005-03-24 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
CA2549386C (en) 2003-12-17 2014-07-29 Praecis Pharmaceuticals, Inc. Methods for synthesis of encoded libraries
US7972994B2 (en) 2003-12-17 2011-07-05 Glaxosmithkline Llc Methods for synthesis of encoded libraries
DE602005017370D1 (en) 2004-03-22 2009-12-10 Nuevolution As LIGATION CODING USING OLIGONUCLEOTIDE COMPONENTS
EP2368868A1 (en) 2005-10-28 2011-09-28 Praecis Pharmaceuticals Inc. Methods for identifying compounds of interest using encoded libraries
DK3305900T3 (en) 2005-12-01 2021-10-25 Nuevolution As ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
NZ594420A (en) 2009-02-13 2013-06-28 Chem Inc X Methods of creating and screening dna-encoded libraries
SI2558577T1 (en) 2010-04-16 2019-05-31 Nuevolution A/S Bi-functional complexes and methods for making and using such complexes
EP2748357B1 (en) 2011-09-07 2018-04-04 X-Chem, Inc. Methods for tagging dna-encoded libraries
EP3851529A1 (en) 2012-07-13 2021-07-21 X-Chem, Inc. Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
CN115820806A (en) 2016-06-16 2023-03-21 哈斯达克科学公司 Combinatorial synthesis of oligonucleotide directed and recorded coded probe molecules
WO2018204420A1 (en) 2017-05-02 2018-11-08 Haystack Sciences Corporation Molecules for verifying oligonucleotide directed combinatorial synthesis and methods of making and using the same
MX2021003158A (en) 2018-09-18 2021-07-16 Nikang Therapeutics Inc Fused tricyclic ring derivatives as src homology-2 phosphatase inhibitors.

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763281A (en) * 1970-06-26 1973-10-02 Stauffer Chemical Co Ureidoalkylphosphonates
US4822731A (en) * 1986-01-09 1989-04-18 Cetus Corporation Process for labeling single-stranded nucleic acids and hybridizaiton probes
US5639603A (en) * 1991-09-18 1997-06-17 Affymax Technologies N.V. Synthesizing and screening molecular diversity
WO1993006121A1 (en) * 1991-09-18 1993-04-01 Affymax Technologies N.V. Method of synthesizing diverse collections of oligomers
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
WO1994024143A1 (en) * 1993-04-12 1994-10-27 Northwestern University Method of forming oligonucleotides
US5681943A (en) * 1993-04-12 1997-10-28 Northwestern University Method for covalently linking adjacent oligonucleotides
US5473060A (en) * 1993-07-02 1995-12-05 Lynx Therapeutics, Inc. Oligonucleotide clamps having diagnostic applications
US5571903A (en) * 1993-07-09 1996-11-05 Lynx Therapeutics, Inc. Auto-ligating oligonucleotide compounds
US5503805A (en) * 1993-11-02 1996-04-02 Affymax Technologies N.V. Apparatus and method for parallel coupling reactions
US6165778A (en) * 1993-11-02 2000-12-26 Affymax Technologies N.V. Reaction vessel agitation apparatus
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5843650A (en) * 1995-05-01 1998-12-01 Segev; David Nucleic acid detection and amplification by chemical linkage of oligonucleotides
US5830658A (en) * 1995-05-31 1998-11-03 Lynx Therapeutics, Inc. Convergent synthesis of branched and multiply connected macromolecular structures
US5780613A (en) * 1995-08-01 1998-07-14 Northwestern University Covalent lock for self-assembled oligonucleotide constructs
DE69835143T2 (en) * 1997-01-21 2007-06-06 The General Hospital Corp., Boston SELECTION OF PROTEINS BY THE RNA PROTEIN FUSIONS
ATE250668T1 (en) * 1997-05-28 2003-10-15 Discerna Ltd RIBOSOME COMPLEXES AS SELECTION PARTICLES FOR IN VITRO DISPLAY AND EVOLUTION OF PROTEINS
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
US6143503A (en) * 1998-04-17 2000-11-07 Whitehead Institute For Biomedical Research Use of a ribozyme to join nucleic acids and peptides
KR20020033743A (en) * 1999-07-27 2002-05-07 추후기재 Peptide acceptor ligation methods
DE60002821T2 (en) * 1999-08-27 2004-05-06 Japan Science And Technology Corp., Kawaguchi REVERSIBLE PHOTOCOUPLING NUCLEIC ACID AND PHOSPHORAMIDITE
EP1832567A3 (en) * 2001-03-19 2009-08-26 President And Fellows Of Harvard College Evolving new molecular function

Also Published As

Publication number Publication date
EP1487850A2 (en) 2004-12-22
US20050247001A1 (en) 2005-11-10
WO2003078446A3 (en) 2003-12-31
WO2003078446A2 (en) 2003-09-25

Similar Documents

Publication Publication Date Title
AU2003218629A1 (en) A building block forming a c-c or a c-hetero atom bond uponreaction
AU2003303688A1 (en) Interlocking building block
AU2003214032A1 (en) A building block forming a c=c double bond upon reaction
AU2003253069A1 (en) A building block forming a c-c bond upon reaction
AU2002952064A0 (en) A ladder
AU2003232274A1 (en) A building element arrangement
AU2003285525A1 (en) Building
AU2003269462A1 (en) Building structures
AU2002301430A1 (en) A building construction
GB0202357D0 (en) Fab-brick building set
AU2003224305A1 (en) Modular buildings
AU2003251054A1 (en) Buildings
AU2003283046A1 (en) Building accessory
AU2003210330A1 (en) Component for a building kit
AU2003906537A0 (en) A Building Block
AU2002325585A1 (en) Building mortar
AU2002100600A4 (en) A building product
AU2003901614A0 (en) A building extension
GB0211853D0 (en) A building block
AU2003211460A1 (en) Building structure
AUPS255802A0 (en) A building product
AU2002950578A0 (en) A building product
AUPS114502A0 (en) Building blocks
AUPS102402A0 (en) Building component
AUPS253502A0 (en) Building component

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase