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AU2002251481A1 - Carboxylic acid derivative and salt thereof - Google Patents

Carboxylic acid derivative and salt thereof

Info

Publication number
AU2002251481A1
AU2002251481A1 AU2002251481A AU2002251481A AU2002251481A1 AU 2002251481 A1 AU2002251481 A1 AU 2002251481A1 AU 2002251481 A AU2002251481 A AU 2002251481A AU 2002251481 A AU2002251481 A AU 2002251481A AU 2002251481 A1 AU2002251481 A1 AU 2002251481A1
Authority
AU
Australia
Prior art keywords
salt
carboxylic acid
acid derivative
derivative
carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2002251481A
Other versions
AU2002251481B2 (en
Inventor
Richard Clark
Eita Emori
Hitoshi Harada
Taro Hihara
Takashi Inoue
Shunji Kasai
Fumiyoshi Matsuura
Sadakazu Miyashita
Kaya Ohashi
Masanobu Shinoda
Kazuto Yamazaki
Hideki Yoshitomi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co Ltd filed Critical Eisai R&D Management Co Ltd
Priority claimed from PCT/JP2002/003866 external-priority patent/WO2002100812A1/en
Publication of AU2002251481A1 publication Critical patent/AU2002251481A1/en
Assigned to EISAI R&D MANAGEMENT CO., LTD. reassignment EISAI R&D MANAGEMENT CO., LTD. Request for Assignment Assignors: EISAI CO., LTD.
Application granted granted Critical
Publication of AU2002251481B2 publication Critical patent/AU2002251481B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

AU2002251481A 2001-04-20 2002-04-18 Carboxylic acid derivative and salt thereof Ceased AU2002251481B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2001123346 2001-04-20
JP2001-123346 2001-04-20
JP2002-36274 2002-02-14
JP2002036274 2002-02-14
PCT/JP2002/003866 WO2002100812A1 (en) 2001-04-20 2002-04-18 Carboxylic acid derivative and salt thereof

Publications (2)

Publication Number Publication Date
AU2002251481A1 true AU2002251481A1 (en) 2003-05-15
AU2002251481B2 AU2002251481B2 (en) 2007-08-09

Family

ID=26613950

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002251481A Ceased AU2002251481B2 (en) 2001-04-20 2002-04-18 Carboxylic acid derivative and salt thereof

Country Status (19)

Country Link
US (1) US7544835B2 (en)
EP (1) EP1380562A4 (en)
JP (1) JP4131698B2 (en)
KR (1) KR100888001B1 (en)
CN (1) CN100522944C (en)
AU (1) AU2002251481B2 (en)
BR (1) BR0209027A (en)
CA (1) CA2442319C (en)
CZ (1) CZ20032727A3 (en)
HU (1) HUP0303810A3 (en)
IL (1) IL157731A0 (en)
MX (1) MXPA03009565A (en)
NO (1) NO329995B1 (en)
NZ (2) NZ528655A (en)
PL (1) PL206767B1 (en)
RU (1) RU2316537C2 (en)
SG (1) SG161743A1 (en)
TW (1) TWI311133B (en)
WO (1) WO2002100812A1 (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO930697A0 (en) * 1997-09-19 1997-10-09 Walter And Eliza Hall Institute Of Medical Research, The Catalytic antibodies and a method of producing same
JP4256166B2 (en) * 2001-03-28 2009-04-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 Carboxylic acid compound
EP1375472A4 (en) 2001-03-30 2008-12-10 Eisai R&D Man Co Ltd Benzene compound and salt thereof
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
WO2002098840A1 (en) 2001-06-04 2002-12-12 Eisai Co., Ltd. Carboxylic acid derivative and medicine comprising salt or ester of the same
CN1543451A (en) * 2001-06-07 2004-11-03 Receptor modulators activated by peroxizonal proliferators (ppar)
US7371777B2 (en) 2001-08-17 2008-05-13 Eisai Co., Ltd. Cyclic compound and PPAR agonist
SE0104333D0 (en) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
US7816385B2 (en) * 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
US20060177444A1 (en) * 2003-03-20 2006-08-10 Tatsuo Horizoe Concomitant drug as therapeutic agent for inflammatory bowel disease
JP2007186515A (en) * 2003-05-02 2007-07-26 Takara Bio Inc Curative agent
MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
GB0314131D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
WO2005014755A1 (en) * 2003-08-08 2005-02-17 Ube Industries, Ltd. Alkynyl group-substituted condensed heterocyclic compound, method for producing same, and organic electroluminescent device using same
AU2004267085B2 (en) * 2003-08-20 2010-09-16 Pharmacyclics, Inc. Acetylene derivatives as inhibitors of histone deacetylase
WO2005086661A2 (en) 2004-02-27 2005-09-22 Amgen Inc. Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
WO2005093423A2 (en) * 2004-03-26 2005-10-06 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with peroxisome proliferative activated receptor alpha (ppara)
WO2005105726A1 (en) 2004-05-05 2005-11-10 Novo Nordisk A/S Novel compounds, their preparation and use
JP4981662B2 (en) 2004-05-05 2012-07-25 ハイ・ポイント・ファーマスーティカルズ、エルエルシー New compounds, their preparation and use
FR2872159B1 (en) * 2004-06-28 2007-10-05 Merck Sante Soc Par Actions Si NOVEL PHENYL CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES
AU2005259579A1 (en) * 2004-07-01 2006-01-12 F. Hoffmann-La Roche Ag Phenyl derivatives comprising an acetylene group
US7405236B2 (en) * 2004-08-16 2008-07-29 Hoffman-La Roche Inc. Indole derivatives comprising an acetylene group
ITMI20041825A1 (en) * 2004-09-24 2004-12-24 Medestea Res & Production Srl RECEPTOR AGONISTS ACTIVATING THE PROLIFERATION OF PEROXYSOMES, USEFUL IN THE PREVENTION OR TREATMENT OF GASTRITIS
US20090069591A1 (en) * 2005-04-19 2009-03-12 Eisai R & D Management Co., Ltd. Calcium Bis [ (2S) -3- [3-[ (2S) -3- (4-Chloro-2-Cyanophenoxy) -2- Fluoropropoxy]Phenyl] -2- Isopropoxypropionate] and Intermediate Thereof
US7816405B2 (en) * 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
US7465804B2 (en) 2005-05-20 2008-12-16 Amgen Inc. Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders
ES2382876T3 (en) 2005-05-31 2012-06-14 Pfizer, Inc. Aryloxy-N-bicyclomethyl-acetamide compounds substituted as VR1 antagonists
TW200718691A (en) * 2005-06-10 2007-05-16 Sigma Tau Ind Farmaceuti Cinnamic and phenylpropiolic acid derivatives useful as anti-tumour agents
ES2372617T3 (en) 2005-06-30 2012-01-24 High Point Pharmaceuticals, Llc PHENOXYACETIC ACIDS AS ACTIVATORS OF PPAR-DELTA.
CA2621949A1 (en) 2005-09-14 2007-03-22 Amgen Inc. Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders
JP2007166908A (en) * 2005-12-19 2007-07-05 Sumitomo Chemical Co Ltd Process for producing optically active 3- (3-hydroxyphenyl) -2-alkoxypropanoic acid or 3- (3-hydroxyphenyl) -2-alkoxypropanoic acid ester
EA201101084A1 (en) 2005-12-22 2012-04-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи PHENOXYACIC ACIDS AS PPAR DELTA ACTIVATORS
JP2009529512A (en) 2006-03-09 2009-08-20 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー Novel compounds, methods for their production and use
NZ574038A (en) 2006-06-27 2011-12-22 Takeda Pharmaceutical Fused cyclic compounds as GPR40 receptor function modulators, for treating diabetes
WO2008030618A1 (en) 2006-09-07 2008-03-13 Amgen Inc. Benzo-fused compounds for use in treating metabolic disorders
AU2007293028B2 (en) 2006-09-07 2012-05-31 Amgen Inc. Heterocyclic GPR40 modulators
CA2679514A1 (en) * 2007-03-01 2008-09-04 Bayer Schering Pharma Aktiengesellschaft 18f fluoro-benzoyl labelled biologically active compounds as diagnostic imaging agents as well as benzotriazol-1-yloxy-benzoyl, 2,5-dioxo-pyrrolidin-1-yloxy-benzoyl and trimethylammonio-benzoyl precursers
ES2550479T3 (en) * 2007-04-05 2015-11-10 Daiichi Sankyo Company, Limited Condensed bicyclic heteroaryl derivatives
US7572934B2 (en) 2007-04-16 2009-08-11 Amgen Inc. Substituted biphenyl GPR40 modulators
KR101196680B1 (en) 2007-06-29 2012-11-06 어큐셀라 인코포레이티드 Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders
BRPI0818253A2 (en) 2007-10-10 2015-04-07 Amgen Inc Substituted biphenyl gpr40 modulators
US8450522B2 (en) 2008-03-06 2013-05-28 Amgen Inc. Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders
ES2450567T3 (en) 2008-10-15 2014-03-25 Amgen, Inc GPR40 spirocyclic modulators
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
EP2759533B1 (en) * 2011-09-22 2017-08-02 Takeda Pharmaceutical Company Limited Condensed heterocyclic compound
KR102157912B1 (en) * 2012-08-03 2020-09-21 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 Enzyme-activating compounds and compositions
CN109400502A (en) * 2013-07-22 2019-03-01 新陈代谢解决方案开发公司 The regulated compound of PPAR- for treating metabolic disease
PE20160901A1 (en) * 2013-12-18 2016-08-27 Astex Therapeutics Ltd NRF2 REGULATORS
EP3240785B1 (en) 2014-12-29 2021-07-07 The United States of America, as represented by The Secretary, Department of Health and Human Services Small molecule inhibitors of lactate dehydrogenase and methods of use thereof
PL3307739T3 (en) 2015-06-15 2021-05-31 Glaxosmithkline Intellectual Property Development Limited Nrf2 regulators
US10272095B2 (en) 2015-06-15 2019-04-30 GlaxoSmithKline Intellectual Propert Development Limited NRF2 regulators
EP3359532A1 (en) 2015-10-06 2018-08-15 GlaxoSmithKline Intellectual Property Development Limited Biaryl pyrazoles as nrf2 regulators

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5649336A (en) 1979-09-05 1981-05-02 Glaxo Group Ltd Phenol derivative* its manufacture and its use
DE3026924A1 (en) * 1980-07-16 1982-02-18 Klinge Pharma GmbH & Co, 8000 München 1,3-Di:phenoxy-propan-2-ol derivs. - used as hypolipaemics to reduce tri:glyceride and cholesterol levels in the blood
JPS5764639A (en) * 1980-10-04 1982-04-19 Nippon Zoki Pharmaceut Co Ltd Novel stilbene derivative, its preparation, and medical composition containing the same as active ingredent
DE3682160D1 (en) * 1985-10-16 1991-11-28 Merck Frosst Canada Inc 2-SUBSTITUTED CHINOLINE.
EP0394440B1 (en) * 1987-10-20 1994-05-11 Otsuka Pharmaceutical Co., Ltd. Phenylcarboxylic acid derivatives
JPH02169584A (en) * 1988-12-22 1990-06-29 Mitsubishi Kasei Corp Vinylthiazole derivatives and drugs containing them as active ingredients
NO179246C (en) * 1991-11-20 1996-09-04 Sankyo Co Aromatic amino-alcohol derivatives and intermediates for their preparation
PL176885B1 (en) * 1992-07-03 1999-08-31 Smithkline Beecham Plc Pharmaceutic composition
GB9225386D0 (en) * 1992-12-04 1993-01-27 Smithkline Beecham Plc Novel compounds
GB9315148D0 (en) * 1993-07-22 1993-09-08 Smithkline Beecham Plc Novel compounds
JP3144624B2 (en) 1995-06-02 2001-03-12 杏林製薬株式会社 N-benzyldioxothiazolidylbenzamide derivative and method for producing the same
AU740444B2 (en) * 1996-08-19 2001-11-01 Japan Tobacco Inc. Propionic acid derivatives and use thereof
ES2320181T3 (en) 1997-07-24 2009-05-19 Astellas Pharma Inc. PHARMACEUTICAL COMPOSITIONS THAT HAVE A REDUCING EFFECT OF CHOLESTEROL.
AU738134B2 (en) 1997-10-02 2001-09-06 Sankyo Company Limited Amidocarboxylic acid derivatives
CN1302206A (en) 1997-10-17 2001-07-04 阿温蒂斯药物制品公司 Therapeutic uses of quinoline derivatives
US6130214A (en) 1997-10-27 2000-10-10 Dr. Reddy's Research Foundation Benzothiazin and benzoxazin derivatives; their preparation and uses
JPH11152269A (en) 1997-11-20 1999-06-08 Teijin Ltd Biphenylamindine derivative
MY153569A (en) 1998-01-20 2015-02-27 Mitsubishi Tanabe Pharma Corp Inhibitors of ?4 mediated cell adhesion
US6417185B1 (en) 1998-06-19 2002-07-09 Chiron Corporation Inhibitors of glycogen synthase kinase 3
FR2781222A1 (en) 1998-07-17 2000-01-21 Lipha New cyclic peroxisome proliferator activated receptor activators, used to prevent or treat dyslipidemia, atherosclerosis and diabetes
RU2267484C2 (en) 1999-04-28 2006-01-10 Авентис Фарма Дойчланд Гмбх Derivatives of diarylic acid and pharmaceutical composition based on thereof
JP2002543065A (en) * 1999-04-28 2002-12-17 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Triaryl acid derivatives as PPAP receptor ligands
JP4618845B2 (en) * 1999-06-09 2011-01-26 杏林製薬株式会社 Substituted phenylpropionic acid derivatives as human peroxisome proliferator-activated receptor (PPAR) alpha agonists
DE60025621T2 (en) 1999-09-17 2006-11-23 Kyorin Pharmaceutical Co., Ltd. O anisamide DERIVATIVES
TWI262185B (en) 1999-10-01 2006-09-21 Eisai Co Ltd Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
DE19947457A1 (en) 1999-10-02 2001-04-05 Aventis Pharma Gmbh New 2'-aminomethyl-biphenyl-2-carboxamide derivatives, are potassium channel blockers especially useful for treating re-entry or supraventricular arrhythmia or atrial fibrillation or flutter
ES2225252T3 (en) 1999-11-10 2005-03-16 Takeda Chemical Industries, Ltd. 5-MEMBER N-HETEROCICLIC COMPOUNDS WITH HYPOGLUCEMIC AND HYPOLIPIDEMIC ACTIVITY.
AU2831801A (en) 2000-01-28 2001-08-07 Novo Nordisk A/S Alkynylsubstituted propionic acid derivatives and their use against diabetes and obesity
PL357010A1 (en) 2000-01-28 2004-07-12 Novo Nordisk A/S Propionic acid derivatives and their use in the treatment of diabetes and obesity
JP2001261612A (en) 2000-03-22 2001-09-26 Mitsui Chemicals Inc Catecholpropionic acid derivative and nuclear receptor agonist containing the same as active ingredient
ES2312432T3 (en) 2000-05-29 2009-03-01 Kyorin Pharmaceutical Co., Ltd. DERIVATIVES OF THE SUBSTITUTED PHENYLPROPIONIC ACID.
FR2812876B1 (en) 2000-08-08 2002-09-27 Galderma Res & Dev NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
CA2426430C (en) 2000-10-20 2014-10-07 Biocryst Pharmaceuticals, Inc. Biaryl compounds as serine protease inhibitors
WO2002042273A2 (en) 2000-11-07 2002-05-30 Bristol-Myers Squibb Company Acid derivatives useful as serine protease inhibitors
JP4256166B2 (en) * 2001-03-28 2009-04-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 Carboxylic acid compound
EP1375472A4 (en) * 2001-03-30 2008-12-10 Eisai R&D Man Co Ltd Benzene compound and salt thereof
WO2002080899A1 (en) 2001-03-30 2002-10-17 Eisai Co., Ltd. Remedial agent for digestive disease
WO2002083616A1 (en) 2001-04-10 2002-10-24 Sankyo Company, Limited α-SUBSTITUTED φ-ARYLFATTY ACID DERIVATIVE
TWI311133B (en) 2001-04-20 2009-06-21 Eisai R&D Man Co Ltd Carboxylic acid derivativeand the salt thereof
WO2002098840A1 (en) * 2001-06-04 2002-12-12 Eisai Co., Ltd. Carboxylic acid derivative and medicine comprising salt or ester of the same
US7371777B2 (en) * 2001-08-17 2008-05-13 Eisai Co., Ltd. Cyclic compound and PPAR agonist
FR2833949B1 (en) 2001-12-21 2005-08-05 Galderma Res & Dev NOVEL PPARy RECEPTOR ACTIVATION LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN MEDICINE AND COSMETICS

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