AU2002230593A1 - Nanoparticles having oligonucleotides attached thereto and uses therefor - Google Patents
Nanoparticles having oligonucleotides attached thereto and uses thereforInfo
- Publication number
- AU2002230593A1 AU2002230593A1 AU2002230593A AU3059302A AU2002230593A1 AU 2002230593 A1 AU2002230593 A1 AU 2002230593A1 AU 2002230593 A AU2002230593 A AU 2002230593A AU 3059302 A AU3059302 A AU 3059302A AU 2002230593 A1 AU2002230593 A1 AU 2002230593A1
- Authority
- AU
- Australia
- Prior art keywords
- nanoparticles
- oligonucleotides attached
- uses therefor
- therefor
- oligonucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- General Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Composite Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25441800P | 2000-12-08 | 2000-12-08 | |
| US25439200P | 2000-12-08 | 2000-12-08 | |
| US60/254,392 | 2000-12-08 | ||
| US60/254,418 | 2000-12-08 | ||
| US25523500P | 2000-12-11 | 2000-12-11 | |
| US25523600P | 2000-12-11 | 2000-12-11 | |
| US60/255,236 | 2000-12-11 | ||
| US60/255,235 | 2000-12-11 | ||
| US09/760,500 | 2001-01-12 | ||
| US09/760,500 US6767702B2 (en) | 1996-07-29 | 2001-01-12 | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US09/820,279 US6750016B2 (en) | 1996-07-29 | 2001-03-28 | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US09/820,279 | 2001-03-28 | ||
| US28264001P | 2001-04-09 | 2001-04-09 | |
| US60/282,640 | 2001-04-09 | ||
| US09/927,777 | 2001-08-10 | ||
| US09/927,777 US20020172953A1 (en) | 1996-07-29 | 2001-08-10 | Movement of biomolecule-coated nanoparticles in an electric field |
| PCT/US2001/046418 WO2002046472A2 (en) | 2000-12-08 | 2001-12-07 | Nanoparticles having oligonucleotides attached thereto and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002230593A1 true AU2002230593A1 (en) | 2002-06-18 |
Family
ID=27575286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002230593A Abandoned AU2002230593A1 (en) | 2000-12-08 | 2001-12-07 | Nanoparticles having oligonucleotides attached thereto and uses therefor |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1356109A2 (en) |
| AU (1) | AU2002230593A1 (en) |
| WO (1) | WO2002046472A2 (en) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6750016B2 (en) | 1996-07-29 | 2004-06-15 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US6984491B2 (en) | 1996-07-29 | 2006-01-10 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US7098320B1 (en) | 1996-07-29 | 2006-08-29 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US6582921B2 (en) | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
| US6506564B1 (en) | 1996-07-29 | 2003-01-14 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| EP1818417B1 (en) | 1996-07-29 | 2014-02-12 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US7169556B2 (en) | 1996-07-29 | 2007-01-30 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US6974669B2 (en) | 2000-03-28 | 2005-12-13 | Nanosphere, Inc. | Bio-barcodes based on oligonucleotide-modified nanoparticles |
| JP3650582B2 (en) | 1998-11-30 | 2005-05-18 | ナノスフェアー インコーポレイテッド | Polymer-nanoparticle hybrid particles |
| JP2004501340A (en) | 2000-01-13 | 2004-01-15 | ナノスフェアー インコーポレイテッド | Oligonucleotide-attached nanoparticles and methods of use |
| US6602669B2 (en) | 2000-07-11 | 2003-08-05 | Northwestern University | Method of detection by enhancement of silver staining |
| US7147687B2 (en) | 2001-05-25 | 2006-12-12 | Nanosphere, Inc. | Non-alloying core shell nanoparticles |
| US7238472B2 (en) | 2001-05-25 | 2007-07-03 | Nanosphere, Inc. | Non-alloying core shell nanoparticles |
| US7186814B2 (en) | 2001-11-09 | 2007-03-06 | Nanosphere, Inc. | Bioconjugate-nanoparticle probes |
| US20030211488A1 (en) | 2002-05-07 | 2003-11-13 | Northwestern University | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection |
| JP2005532456A (en) | 2002-07-02 | 2005-10-27 | ナノスフェアー インコーポレイテッド | Nanoparticle polyanion complex and its use in the detection of analytes |
| US7153687B2 (en) | 2002-08-13 | 2006-12-26 | Hong Kong Dna Chips Limited | Apparatus and methods for detecting DNA in biological samples |
| EP1867990A1 (en) * | 2006-06-14 | 2007-12-19 | Koninklijke Philips Electronics N.V. | Sensitive assay through amplification of a label signal |
| EP1933142B1 (en) | 2006-12-11 | 2011-08-17 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| EP1933139B1 (en) * | 2006-12-11 | 2011-09-28 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| EP1933140B1 (en) | 2006-12-11 | 2011-08-17 | AraGen Biotechnology Co. Ltd. | Antibody detection method involving an oligonucleotide enhanced collodial gold signal |
| EP1933147B1 (en) * | 2006-12-11 | 2011-08-17 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| EP1933144B1 (en) * | 2006-12-11 | 2011-09-28 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| EP1933141B1 (en) * | 2006-12-11 | 2011-08-17 | AraGen Biotechnology Co. Ltd. | Antigen detection method involving an oligonucleotide enhanced collodial gold signal |
| EP1933145B1 (en) | 2006-12-11 | 2011-09-28 | AraGen Biotechnology Co. Ltd. | Rapid immunochromatographic detection by amplification of the colloidal gold signal |
| US20110229913A1 (en) * | 2008-11-28 | 2011-09-22 | Infopia Co., Ltd. | Method for Amplification of Signal in Immunochromatographic Assay and Immunochromatographic Kit Using the Method |
| US8835358B2 (en) | 2009-12-15 | 2014-09-16 | Cellular Research, Inc. | Digital counting of individual molecules by stochastic attachment of diverse labels |
| US9335292B2 (en) | 2011-10-13 | 2016-05-10 | Auburn University | Electrochemical proximity assay |
| EP2820158B1 (en) | 2012-02-27 | 2018-01-10 | Cellular Research, Inc. | Compositions and kits for molecular counting |
| EP3480321B8 (en) | 2013-08-28 | 2021-03-10 | Becton, Dickinson and Company | Massively parallel single cell analysis |
| ES2836802T3 (en) | 2015-02-27 | 2021-06-28 | Becton Dickinson Co | Spatially addressable molecular barcodes |
| ES2934982T3 (en) | 2015-03-30 | 2023-02-28 | Becton Dickinson Co | Methods for encoding with combinatorial barcodes |
| WO2016172373A1 (en) | 2015-04-23 | 2016-10-27 | Cellular Research, Inc. | Methods and compositions for whole transcriptome amplification |
| ES2745694T3 (en) | 2015-09-11 | 2020-03-03 | Cellular Res Inc | Methods and compositions for nucleic acid library normalization |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| CA3034924A1 (en) | 2016-09-26 | 2018-03-29 | Cellular Research, Inc. | Measurement of protein expression using reagents with barcoded oligonucleotide sequences |
| WO2018144240A1 (en) | 2017-02-01 | 2018-08-09 | Cellular Research, Inc. | Selective amplification using blocking oligonucleotides |
| WO2018165566A1 (en) | 2017-03-09 | 2018-09-13 | Auburn University | Differential circuit for background correction in electrochemical measurements |
| US10676779B2 (en) | 2017-06-05 | 2020-06-09 | Becton, Dickinson And Company | Sample indexing for single cells |
| US11505799B2 (en) | 2017-07-07 | 2022-11-22 | Innamed, Inc. | Aptamers for measuring lipoprotein levels |
| WO2019213294A1 (en) | 2018-05-03 | 2019-11-07 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| CN112243461B (en) | 2018-05-03 | 2024-07-12 | 贝克顿迪金森公司 | Molecular barcoding at opposite transcript ends |
| US11560565B2 (en) | 2018-06-13 | 2023-01-24 | Auburn University | Electrochemical detection nanostructure, systems, and uses thereof |
| JP2022511398A (en) | 2018-10-01 | 2022-01-31 | ベクトン・ディキンソン・アンド・カンパニー | Determining the 5'transcription sequence |
| WO2020097315A1 (en) | 2018-11-08 | 2020-05-14 | Cellular Research, Inc. | Whole transcriptome analysis of single cells using random priming |
| WO2020123384A1 (en) | 2018-12-13 | 2020-06-18 | Cellular Research, Inc. | Selective extension in single cell whole transcriptome analysis |
| US11661631B2 (en) | 2019-01-23 | 2023-05-30 | Becton, Dickinson And Company | Oligonucleotides associated with antibodies |
| EP3924506A1 (en) | 2019-02-14 | 2021-12-22 | Becton Dickinson and Company | Hybrid targeted and whole transcriptome amplification |
| WO2021016239A1 (en) | 2019-07-22 | 2021-01-28 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| EP4407041A3 (en) | 2019-11-08 | 2024-09-25 | Becton Dickinson and Company | Using random priming to obtain full-length v(d)j information for immune repertoire sequencing |
| US11649497B2 (en) | 2020-01-13 | 2023-05-16 | Becton, Dickinson And Company | Methods and compositions for quantitation of proteins and RNA |
| US12188010B2 (en) | 2020-01-29 | 2025-01-07 | Becton, Dickinson And Company | Barcoded wells for spatial mapping of single cells through sequencing |
| CN115151810A (en) | 2020-02-25 | 2022-10-04 | 贝克顿迪金森公司 | Enables bispecific probes using single-cell samples as single-color compensation controls |
| CN115605614A (en) | 2020-05-14 | 2023-01-13 | 贝克顿迪金森公司（Us） | Primers for immune repertoire profiling |
| US12157913B2 (en) | 2020-06-02 | 2024-12-03 | Becton, Dickinson And Company | Oligonucleotides and beads for 5 prime gene expression assay |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| CN112698020B (en) * | 2020-11-12 | 2022-08-26 | 中山大学 | Multimodal coupling analysis method of cross response system based on DNA-AuNP coding |
| US11739443B2 (en) | 2020-11-20 | 2023-08-29 | Becton, Dickinson And Company | Profiling of highly expressed and lowly expressed proteins |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9212164D0 (en) * | 1992-06-09 | 1992-07-22 | Medical Res Council | Preparation of nucleic acids |
| EP1818417B1 (en) * | 1996-07-29 | 2014-02-12 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| WO1998017317A2 (en) * | 1996-10-23 | 1998-04-30 | Skw Trostberg Aktiengesellschaft | Process for producing biologically active polymer nanoparticle-nucleic acid conjugates |
| US5900481A (en) * | 1996-11-06 | 1999-05-04 | Sequenom, Inc. | Bead linkers for immobilizing nucleic acids to solid supports |
| US6287765B1 (en) * | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
-
2001
- 2001-12-07 AU AU2002230593A patent/AU2002230593A1/en not_active Abandoned
- 2001-12-07 WO PCT/US2001/046418 patent/WO2002046472A2/en not_active Application Discontinuation
- 2001-12-07 EP EP01990826A patent/EP1356109A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1356109A2 (en) | 2003-10-29 |
| WO2002046472A2 (en) | 2002-06-13 |
| WO2002046472A3 (en) | 2003-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2002230593A1 (en) | Nanoparticles having oligonucleotides attached thereto and uses therefor | |
| EP1247815A3 (en) | Modified oligonucleotides and uses thereof | |
| AU2002235128A1 (en) | Expression miniarrays and uses thereof | |
| AU2001280796A1 (en) | Electrowetting-driven micropumping | |
| AU2001297913A1 (en) | Polyvalent nanoparticles | |
| AU2002329759A1 (en) | Methyltransferase genes and uses thereof | |
| AU2001240637A1 (en) | Novel imidazotriazinones and the use thereof | |
| AU2002211717A1 (en) | Stresscopins and their uses | |
| AU2001272011A1 (en) | Siderophores-producing bifidobacteria thereby and uses thereof | |
| GB0016844D0 (en) | Nanoparticles | |
| EP1354950A4 (en) | Nf-kb activating gene | |
| EP1368051A4 (en) | Urocortin-iii and uses thereof | |
| AU2001292936A1 (en) | Octahydro-indolizines and quinolizines and hexahydro-pyrrolizines | |
| AU2001295185A1 (en) | Multiplexing-interleaving and demultiplexing-deinterleaving | |
| AU2002210916A1 (en) | Endoscope attachment and endoscope | |
| AU2001229439A1 (en) | Bioconjugates and uses thereof | |
| AU3732500A (en) | Beclin and uses thereof | |
| AU2001269276A1 (en) | Drills and their manufacture | |
| AU4432001A (en) | Trityl-type compounds and their use | |
| AU2000231564A1 (en) | Phosphororganic compounds and the use thereof | |
| AU2001252062A1 (en) | Steatosis-modulating factors and uses thereof | |
| AU2001228624A1 (en) | Implements and their manufacture | |
| AU5979300A (en) | Angiopoietin-6 and uses thereof | |
| AU2001277519A1 (en) | Bio-probes and use thereof | |
| AU2002358354A1 (en) | Sugar-protein conjugates and their formation |