[go: up one dir, main page]

AU2002218893A1 - Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability - Google Patents

Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability

Info

Publication number
AU2002218893A1
AU2002218893A1 AU2002218893A AU2002218893A AU2002218893A1 AU 2002218893 A1 AU2002218893 A1 AU 2002218893A1 AU 2002218893 A AU2002218893 A AU 2002218893A AU 2002218893 A AU2002218893 A AU 2002218893A AU 2002218893 A1 AU2002218893 A1 AU 2002218893A1
Authority
AU
Australia
Prior art keywords
culture
compositions
cell lines
embryonic stem
transmission capability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002218893A
Inventor
Luc Schoonjans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thromb X NV
Original Assignee
Thromb X NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thromb X NV filed Critical Thromb X NV
Publication of AU2002218893A1 publication Critical patent/AU2002218893A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5415—Leukaemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Environmental Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2002218893A 2001-12-21 2001-12-21 Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability Abandoned AU2002218893A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BE2001/000221 WO2003054169A1 (en) 2001-12-21 2001-12-21 Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability

Publications (1)

Publication Number Publication Date
AU2002218893A1 true AU2002218893A1 (en) 2003-07-09

Family

ID=3862579

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002218893A Abandoned AU2002218893A1 (en) 2001-12-21 2001-12-21 Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability

Country Status (2)

Country Link
AU (1) AU2002218893A1 (en)
WO (1) WO2003054169A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4408371B2 (en) 2001-12-21 2010-02-03 トロンボジェニクス・ナムローゼ・フエンノートシャップ Composition for in vitro induction and culture of embryonic stem (ES) cells having germline transmission ability
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
PL1888123T3 (en) 2005-06-08 2013-06-28 Janssen Biotech Inc A cellular therapy for ocular degeneration
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
PL2046946T3 (en) * 2006-06-26 2017-04-28 Lifescan, Inc. Pluripotent stem cell culture
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CN101952415B (en) 2007-07-31 2017-06-27 生命扫描有限公司 The differentiation of human embryo stem cell
JP5710264B2 (en) 2007-11-27 2015-04-30 ライフスキャン・インコーポレイテッドＬｉｆｅｓｃａｎ，Ｉｎｃ． Differentiation of human embryonic stem cells
BRPI0706146A2 (en) * 2007-12-14 2009-08-18 Ouro Fino Sa production of bos taurus growth hormone (gh) by pichia pastoris yeast using a synthetic gene sequence
EP2254990B1 (en) 2008-02-21 2020-04-15 Janssen Biotech, Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
CN102159703B (en) 2008-06-30 2015-11-25 森托科尔奥索生物科技公司 The differentiation of multipotential stem cell
CN102272291B (en) 2008-10-31 2018-01-16 詹森生物科技公司 Differentiation of the human embryo stem cell to pancreatic endocrine pedigree
JP2012507289A (en) 2008-10-31 2012-03-29 ヤンセン バイオテツク，インコーポレーテツド Differentiation of human embryonic stem cells into the pancreatic endocrine system
CA2744227C (en) 2008-11-20 2018-10-02 Centocor Ortho Biotech Inc. Methods and compositions for cell attachment and cultivation on planar substrates
MX2011005288A (en) 2008-11-20 2011-06-01 Centocor Ortho Biotech Inc Pluripotent stem cell culture on micro-carriers.
ES2693088T3 (en) 2009-07-20 2018-12-07 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
JP6219568B2 (en) 2009-07-20 2017-10-25 ヤンセン バイオテツク，インコーポレーテツド Differentiation of human embryonic stem cells
SG177416A1 (en) 2009-07-20 2012-02-28 Janssen Biotech Inc Differentiation of human embryonic stem cells
US9133439B2 (en) 2009-12-23 2015-09-15 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
KR101773538B1 (en) 2009-12-23 2017-08-31 얀센 바이오테크 인코포레이티드 Differentiation of human embryonic stem cells
BR112012022145A2 (en) 2010-03-01 2020-10-06 Janssen Biotech, Inc. methods to purify cells derived from pluripotent stem cells
DK2569419T3 (en) 2010-05-12 2019-05-13 Janssen Biotech Inc DIFFERENTIAL HUMAN EMBRYONIC STAMPS
EP3372672A1 (en) 2010-08-31 2018-09-12 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
SG187944A1 (en) 2010-08-31 2013-04-30 Janssen Biotech Inc Differentiation of human embryonic stem cells
BR112013004614A2 (en) 2010-08-31 2024-01-16 Janssen Biotech Inc DIFFERENTIATION OF PLURIPOTENT STEM CELLS
US9388386B2 (en) 2011-12-22 2016-07-12 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into single hormonal insulin positive cells
MX354775B (en) 2012-03-07 2018-03-20 Janssen Biotech Inc Defined media for expansion and maintenance of pluripotent stem cells.
CN108103006A (en) 2012-06-08 2018-06-01 詹森生物科技公司 Differentiation of the human embryo stem cell to pancreatic endocrine cell
WO2014106141A1 (en) 2012-12-31 2014-07-03 Janssen Biotech, Inc. Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
KR102084561B1 (en) 2012-12-31 2020-03-04 얀센 바이오테크 인코포레이티드 Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells
RU2684215C2 (en) 2012-12-31 2019-04-04 Янссен Байотек, Инк. Method for obtaining pancreatic endocrine cells (versions) and method for increasing output of beta cells
JP6588969B2 (en) 2014-05-16 2019-10-09 ヤンセン バイオテツク，インコーポレーテツド Use of small molecules to enhance MAFA expression in pancreatic endocrine cells
MA45479A (en) 2016-04-14 2019-02-20 Janssen Biotech Inc DIFFERENTIATION OF PLURIPOTENT STEM CELLS IN ENDODERMAL CELLS OF MIDDLE INTESTINE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2740320B2 (en) * 1988-08-04 1998-04-15 アムラド・コーポレイション・リミテッド In vitro propagation of embryonic stem cells
ATE142695T1 (en) * 1989-01-10 1996-09-15 Amrad Corp Ltd LEUKEMIA-INHIBITING FACTOR FROM LIVESTOCK SPECIES AND ITS USE TO IMPROVE IMPLANTATION AND DEVELOPMENT OF EMBRYONAL CELLS
AU1274797A (en) * 1995-11-29 1997-06-19 Utah State University Establishment, maintenance, and transfection of totipotent embryonic stem cells from the embryos of domestic animals

Also Published As

Publication number Publication date
WO2003054169A1 (en) 2003-07-03

Similar Documents

Publication Publication Date Title
AU2002218893A1 (en) Compositions for the in vitro derivation and culture of embryonic stem (es) cell lines with germline transmission capability
AU2002319780A1 (en) Alternative compositions and methods for the culture of stem cells
AU2003285172A1 (en) Human embryonic stem cell cultures, and compositions and methods for growing same
AU4323599A (en) Compositions and methods for use in affecting hematopoietic stem cell populations in mammals
AU4965799A (en) Bioreactor and cell culturing processes using the bioreactor
AU1803601A (en) Methods and compositions for the introduction of molecules into cells
EP2266396A3 (en) Modulation of stem cells using zinc finger proteins
AU5886000A (en) Compositions, kits, and methods for modulating survival and differentiation of multi-potential hematopoietic progenitor cells
AU5676701A (en) Novel method of inducing the differentiation of embryonic stem cells into ectodermal cells and use thereof
WO2002077210A3 (en) Methods to culture circovirus
AU2002302819A1 (en) Remodeling of somatic nuclei upon addition of pluripotent cell extracts
AU2003277282A1 (en) The isolation, culture, and use of marine copepods in aquaculture
AU2003296432A1 (en) Methods and compositions for inhibiting the growth of hematopoietic malignant cells
AU2003280687A1 (en) Composition for culturing multipotent stem cells and utilization of the same
WO2005001033A3 (en) Tolerance induction and maintenance in hematopoietic stem cell allografts
PL370703A1 (en) Cell constructs cultured in vitro, preparation and uses
AU2002322519A1 (en) Proteins associated with cell growth, differentiation, and death
AU2002323110A1 (en) Proteins associated with cell growth, differentiation, and death
GB0220145D0 (en) Novel compositions for the in vitro derivation and culture of embryonic stem (ES) cell lines with germline transmission capability
AU2002236984A1 (en) Proteins associated with cell growth, differentiation, and death
AU5617199A (en) Thermostable (in vitro) complex with polymerase activity
AU1224601A (en) In vitro embryo culture device and methods
HUP0501094A2 (en) Somatic cell derived embryonic stem cells and its differentiated cells
AU2002320022A1 (en) Proteins associated with cell growth, differentiation, and death
AU2002250333A1 (en) Fas ligand-expressing hematopoietic cells for transplantation

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase