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AU2001284322A1 - Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem - Google Patents

Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem

Info

Publication number
AU2001284322A1
AU2001284322A1 AU2001284322A AU8432201A AU2001284322A1 AU 2001284322 A1 AU2001284322 A1 AU 2001284322A1 AU 2001284322 A AU2001284322 A AU 2001284322A AU 8432201 A AU8432201 A AU 8432201A AU 2001284322 A1 AU2001284322 A1 AU 2001284322A1
Authority
AU
Australia
Prior art keywords
zolpidem
dimethyl
synthesis
methyl
key intermediate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001284322A
Inventor
Yatendra Kumar
Asok Nath
Mohan Prasad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of AU2001284322A1 publication Critical patent/AU2001284322A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001284322A 2000-08-29 2001-08-28 Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem Abandoned AU2001284322A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN782DE2000 2000-08-29
IN782/DEL/2000 2000-08-29
PCT/IB2001/001558 WO2002018303A2 (en) 2000-08-29 2001-08-28 Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem

Publications (1)

Publication Number Publication Date
AU2001284322A1 true AU2001284322A1 (en) 2002-03-13

Family

ID=11097088

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001284322A Abandoned AU2001284322A1 (en) 2000-08-29 2001-08-28 Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem

Country Status (4)

Country Link
US (1) US6921839B2 (en)
EP (1) EP1370515A2 (en)
AU (1) AU2001284322A1 (en)
WO (1) WO2002018303A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1370515A2 (en) 2000-08-29 2003-12-17 Ranbaxy Laboratories, Ltd. Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem
MXPA05006438A (en) 2002-12-18 2005-09-08 Mallinckrodt Inc Synthesis of heteroaryl acetamides.
EP1660496A1 (en) * 2003-07-31 2006-05-31 Ranbaxy Laboratories Limited Process for the synthesis of zolpidem
US20110077200A1 (en) * 2006-12-06 2011-03-31 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
CN110272414B (en) * 2018-03-14 2020-07-17 新发药业有限公司 Preparation method of zolpidem

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492382A1 (en) * 1980-10-22 1982-04-23 Synthelabo IMIDAZO (1,2-A) PYRIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF
EP1005863A1 (en) 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
ES2159260B1 (en) 1999-06-22 2002-05-01 Smithkline Beechan Plc NEW PAROXETINE METHANOSULPHONATE COMPOSITION
PT1475093E (en) 2000-04-24 2006-11-30 Teva Pharma Micronized zolpidem hemitartrate
EP1370515A2 (en) 2000-08-29 2003-12-17 Ranbaxy Laboratories, Ltd. Synthesis of n,n-dimethyl-3-(4-methyl) benzoyl propionamide, a key intermediate of zolpidem
US20020183522A1 (en) * 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
DE10121638A1 (en) 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Process for the preparation of imidazopyridines

Also Published As

Publication number Publication date
WO2002018303A2 (en) 2002-03-07
US20040054230A1 (en) 2004-03-18
WO2002018303A3 (en) 2003-10-02
EP1370515A2 (en) 2003-12-17
US6921839B2 (en) 2005-07-26

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