AU2001282335A1 - Crystal structure of a ras-pi3k complex - Google Patents

Crystal structure of a ras-pi3k complex

Info

Publication number: AU2001282335A1
Authority: AU; Australia
Prior art keywords: ras; crystal structure; pi3k complex; pi3k; complex
Prior art date: 2000-08-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001282335A

Inventor

John Eccleston

Michael Pacold

Len Stephens

Roger Williams Sr.

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Medical Research Council

Original Assignee

Medical Research Council

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-24

Filing date

2001-08-24

Publication date

2002-03-04

2001-08-24 Application filed by Medical Research Council filed Critical Medical Research Council

2002-03-04 Publication of AU2001282335A1 publication Critical patent/AU2001282335A1/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Hematology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
General Engineering & Computer Science (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AU2001282335A 2000-08-24 2001-08-24 Crystal structure of a ras-pi3k complex Abandoned AU2001282335A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0020958.5A GB0020958D0 (en)	2000-08-24	2000-08-24	Crystal structure
GB0020958		2000-08-24
PCT/GB2001/003810 WO2002016427A1 (en)	2000-08-24	2001-08-24	Crystal structure of a ras-pi3k complex

Publications (1)

Publication Number	Publication Date
AU2001282335A1 true AU2001282335A1 (en)	2002-03-04

Family

ID=9898289

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001282335A Abandoned AU2001282335A1 (en)	2000-08-24	2001-08-24	Crystal structure of a ras-pi3k complex

Country Status (5)

Country	Link
US (1)	US20040018957A1 (en)
EP (1)	EP1313764A1 (en)
AU (1)	AU2001282335A1 (en)
GB (1)	GB0020958D0 (en)
WO (1)	WO2002016427A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2011146748A1 (en) *	2010-05-21	2011-11-24	New York University	Method of treating cancer by inhibition of protein kinase-like endoplasmic reticulum protein kinase

2000
- 2000-08-24 GB GBGB0020958.5A patent/GB0020958D0/en not_active Ceased
2001
- 2001-08-24 AU AU2001282335A patent/AU2001282335A1/en not_active Abandoned
- 2001-08-24 EP EP01960948A patent/EP1313764A1/en not_active Withdrawn
- 2001-08-24 WO PCT/GB2001/003810 patent/WO2002016427A1/en not_active Application Discontinuation
2003
- 2003-02-21 US US10/371,617 patent/US20040018957A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20040018957A1 (en)	2004-01-29
GB0020958D0 (en)	2000-10-11
EP1313764A1 (en)	2003-05-28
WO2002016427A1 (en)	2002-02-28

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GB0020449D0 (en)	2000-10-11	Crystal structure
AU2001282335A1 (en)	2002-03-04	Crystal structure of a ras-pi3k complex
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AU3816400A (en)	2001-10-15	Structure
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AU2001293663A1 (en)	2002-04-02	Sundial
GB0030424D0 (en)	2001-01-24	Crystal structure
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AU2002212338A1 (en)	2002-05-06	Clock
AU2001292021A1 (en)	2002-04-08	Roll up clock