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AU2001264043A1 - 4-(2-phenylthiazol-5-yl)-1,4-diazabicyclo-(3.2.2)nonane derivatives, preparationand therapeutic use thereof - Google Patents

4-(2-phenylthiazol-5-yl)-1,4-diazabicyclo-(3.2.2)nonane derivatives, preparationand therapeutic use thereof

Info

Publication number
AU2001264043A1
AU2001264043A1 AU2001264043A AU6404301A AU2001264043A1 AU 2001264043 A1 AU2001264043 A1 AU 2001264043A1 AU 2001264043 A AU2001264043 A AU 2001264043A AU 6404301 A AU6404301 A AU 6404301A AU 2001264043 A1 AU2001264043 A1 AU 2001264043A1
Authority
AU
Australia
Prior art keywords
preparationand
phenylthiazol
diazabicyclo
therapeutic use
nonane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001264043A
Inventor
Thierry Gallet
Frederic Galli
Odile Leclerc
Alistair Lochead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Publication of AU2001264043A1 publication Critical patent/AU2001264043A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2001264043A 2000-05-31 2001-05-29 4-(2-phenylthiazol-5-yl)-1,4-diazabicyclo-(3.2.2)nonane derivatives, preparationand therapeutic use thereof Abandoned AU2001264043A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0006978 2000-05-31
FR0006978A FR2809732B1 (en) 2000-05-31 2000-05-31 DERIVATIVES OF 4 (-2-PHENYLTHIAZOL-5-yl) -1,4-DIAZABICYCLO- [3.2.2] NONANE, THEIR PREPARATION AND THEIR THERAPY APPLICATION
PCT/FR2001/001650 WO2001092260A1 (en) 2000-05-31 2001-05-29 4-(2-phenylthiazol-5-yl)-1,4-diazabicyclo-[3.2.2]nonane derivatives, preparation and therapeutic use thereof

Publications (1)

Publication Number Publication Date
AU2001264043A1 true AU2001264043A1 (en) 2001-12-11

Family

ID=8850829

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001264043A Abandoned AU2001264043A1 (en) 2000-05-31 2001-05-29 4-(2-phenylthiazol-5-yl)-1,4-diazabicyclo-(3.2.2)nonane derivatives, preparationand therapeutic use thereof

Country Status (11)

Country Link
US (1) US7001902B2 (en)
EP (1) EP1289987B1 (en)
JP (1) JP4939720B2 (en)
AR (1) AR028649A1 (en)
AT (1) ATE267201T1 (en)
AU (1) AU2001264043A1 (en)
DE (1) DE60103394T2 (en)
FR (1) FR2809732B1 (en)
HU (1) HU229600B1 (en)
TW (1) TW591028B (en)
WO (1) WO2001092260A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0000540D0 (en) 2000-02-18 2000-02-18 Astrazeneca Ab New compounds
FR2832713B1 (en) * 2001-11-23 2004-02-13 Sanofi Synthelabo DERIVATIVES OF 4- (1,3,4-THIADIAZOL-2-YL) -1,4-DIAZABICYCLO [3.2.2] NONANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
SE0202430D0 (en) * 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202465D0 (en) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
MXPA05003317A (en) 2002-09-25 2005-07-05 Memory Pharm Corp Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof.
CA2496585C (en) * 2002-09-30 2012-05-29 Neurosearch A/S Novel 1,4-diazabicycloalkane derivatives, their preparation and use
KR20050062575A (en) * 2002-09-30 2005-06-23 뉴로서치 에이/에스 Novel 1,4-diazabicycloalkane derivatives, their preparation and use
WO2004043960A1 (en) * 2002-11-11 2004-05-27 Neurosearch A/S 1,4-diazabicyclo (3,2,2)nonane derivatives, preparation and therapeutical use thereof
US7223753B2 (en) 2002-11-11 2007-05-29 Neurosearch A/S Diazabicyclic biaryl derivatives
US7396833B2 (en) 2003-12-22 2008-07-08 Memory Pharmaceuticals Corporation Indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof
US20080227772A1 (en) * 2004-02-04 2008-09-18 Neurosearch A/S Diazabicyclic Aryl Derivatives as Nicotinic Acetylcholine Receptor Ligands
KR20060125885A (en) * 2004-02-04 2006-12-06 뉴로서치 에이/에스 Diazabicyclic aryl Derivatives as Choline Receptor Modulators
KR101176670B1 (en) 2004-03-25 2012-08-23 메모리 파마슈티칼스 코포레이션 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
DE602005024677D1 (en) 2004-04-22 2010-12-23 Memory Pharm Corp INDOLE, 1H-INDAZOLE, 1,2-BENZOOXAZOLE, 1,2-BENZOISOTHIAZOLE, THEIR PREPARATION AND USES
RU2386633C2 (en) 2004-05-07 2010-04-20 Мемори Фармасьютиклз Корпорейшн 1h-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles and chromones and synthesis and use thereof
AU2005317280A1 (en) * 2004-12-15 2006-06-22 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
CA2591817A1 (en) 2004-12-22 2006-06-29 Memory Pharmaceuticals Corporation Nicotinic alpha-7 receptor ligands and preparation and uses thereof
DE602006019561D1 (en) 2005-02-16 2011-02-24 Neurosearch As DIAZABICYCLIC ARYL DERIVATIVES AND THEIR USE AS CHINOLINERGIC LIGANDS ON NICOTIN ACETYLCHOLINE RECEPTORS
US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
AU2006323986A1 (en) 2005-12-06 2007-06-14 Neurosearch A/S Novel diazabicyclic aryl derivatives and their medical use
US7910578B2 (en) 2006-05-23 2011-03-22 Neurosearch A/S 8,10-diaza-bicyclo[4.3.1]decane derivatives and their medical use
EP2032575B1 (en) 2006-05-30 2010-04-07 Neurosearch A/S Novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivative and its medical use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN166416B (en) * 1985-09-18 1990-05-05 Pfizer
NZ226000A (en) * 1987-09-10 1991-06-25 Merck Sharp & Dohme Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
US5478939A (en) * 1994-07-20 1995-12-26 American Cyanamid Company (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
FR2786770B1 (en) 1998-12-04 2001-01-19 Synthelabo NONANE 1,4-DIAZABICYCLO [3.2.2.] DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
HUP0302157A3 (en) 2011-03-28
TW591028B (en) 2004-06-11
JP2003535090A (en) 2003-11-25
EP1289987A1 (en) 2003-03-12
EP1289987B1 (en) 2004-05-19
DE60103394T2 (en) 2005-06-02
ATE267201T1 (en) 2004-06-15
WO2001092260A1 (en) 2001-12-06
DE60103394D1 (en) 2004-06-24
US7001902B2 (en) 2006-02-21
HU229600B1 (en) 2014-02-28
FR2809732B1 (en) 2002-07-19
JP4939720B2 (en) 2012-05-30
AR028649A1 (en) 2003-05-21
FR2809732A1 (en) 2001-12-07
US20040029884A1 (en) 2004-02-12
HUP0302157A2 (en) 2003-10-28

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