AU2001258662A1 - Use of a lacrophyl preparation in eye-drops containing therapeutically active compounds - Google Patents
Use of a lacrophyl preparation in eye-drops containing therapeutically active compoundsInfo
- Publication number
- AU2001258662A1 AU2001258662A1 AU2001258662A AU5866201A AU2001258662A1 AU 2001258662 A1 AU2001258662 A1 AU 2001258662A1 AU 2001258662 A AU2001258662 A AU 2001258662A AU 5866201 A AU5866201 A AU 5866201A AU 2001258662 A1 AU2001258662 A1 AU 2001258662A1
- Authority
- AU
- Australia
- Prior art keywords
- eye
- lacrophyl
- active substance
- active compounds
- therapeutically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000003889 eye drop Substances 0.000 title abstract 3
- 229940012356 eye drops Drugs 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- 102000016943 Muramidase Human genes 0.000 abstract 1
- 108010014251 Muramidase Proteins 0.000 abstract 1
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 abstract 1
- 235000010323 ascorbic acid Nutrition 0.000 abstract 1
- 229960005070 ascorbic acid Drugs 0.000 abstract 1
- 239000011668 ascorbic acid Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 229960001484 edetic acid Drugs 0.000 abstract 1
- 235000010335 lysozyme Nutrition 0.000 abstract 1
- 229960000274 lysozyme Drugs 0.000 abstract 1
- 239000004325 lysozyme Substances 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002504 physiological saline solution Substances 0.000 abstract 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention refers to the use of a lacrophyl preparation containing lysozyme, tris(hydroxymethyl)aminomethane, if desired other lacrophyl components, preferably ascorbic acid and/or citric acid and/or ethylenediamine-tetraacetic acid, in the rest distilled water for the dissolution of an active substance being insoluble or only slightly soluble in water or physiological saline, for preparing eye-drops, and/or in case of eye-drops containing an active substance to adjust optionally an active substance medium appropriate to the composition of the native tear and for the microbiological protection of the medium.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0001769 | 2000-05-04 | ||
| HU0001769A HUP0001769A2 (en) | 2000-05-04 | 2000-05-04 | Use of lactophil composition in eye-drops containing pharmaceutical active ingredients |
| PCT/HU2001/000053 WO2001082893A1 (en) | 2000-05-04 | 2001-05-04 | Use of a lacrophyl preparation in eye-drops containing therapeutically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001258662A1 true AU2001258662A1 (en) | 2001-11-12 |
Family
ID=89978306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001258662A Abandoned AU2001258662A1 (en) | 2000-05-04 | 2001-05-04 | Use of a lacrophyl preparation in eye-drops containing therapeutically active compounds |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6949241B2 (en) |
| EP (1) | EP1278511B1 (en) |
| AT (1) | ATE272389T1 (en) |
| AU (1) | AU2001258662A1 (en) |
| CA (1) | CA2407794A1 (en) |
| DE (1) | DE60104670T2 (en) |
| ES (1) | ES2248326T3 (en) |
| HU (1) | HUP0001769A2 (en) |
| WO (1) | WO2001082893A1 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040229814A1 (en) * | 2002-08-28 | 2004-11-18 | James Dillon | Methods and compositions for protecting against cataract development associated with vitrectomies |
| US7220422B2 (en) * | 2003-05-20 | 2007-05-22 | Allergan, Inc. | Methods and compositions for treating eye disorders |
| US20060275278A1 (en) * | 2005-06-02 | 2006-12-07 | Choy Camus K M | Method and ophthalmic formulation for eye protection or treatment |
| US20070259021A1 (en) * | 2006-05-01 | 2007-11-08 | Friedlaender Mitchell H | Compositions, Methods, and Kits for Treating Dry Eye |
| WO2008109397A2 (en) * | 2007-03-02 | 2008-09-12 | Saint Simeon Lda | Novel ophthalmic compositions containing human recombinant lysozyme and use thereof for treating eye conditions and as contact lens solutions |
| CN103182075B (en) * | 2011-12-30 | 2015-07-22 | 沈阳兴齐眼药股份有限公司 | Lysozyme preparation, preparation method thereof, and application thereof |
| US20170202850A1 (en) * | 2014-07-21 | 2017-07-20 | Hiroaki Serizawa | Ophthalmic compositions of rifamycins and uses thereof |
| WO2016077457A1 (en) | 2014-11-11 | 2016-05-19 | Clara Foods Co. | Methods and compositions for egg white protein production |
| WO2017209721A1 (en) | 2016-06-02 | 2017-12-07 | Alemdar Eda | A drug derived from enzymes present in the human saliva for use in preventing corneal clouding or cataract formation |
| MX2022000374A (en) | 2019-07-11 | 2022-03-25 | Clara Foods Co | PROTEIN COMPOSITIONS AND CONSUMABLE PRODUCTS THEREOF. |
| US12096784B2 (en) | 2019-07-11 | 2024-09-24 | Clara Foods Co. | Protein compositions and consumable products thereof |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| JPWO2022138639A1 (en) * | 2020-12-21 | 2022-06-30 | ||
| US12005093B2 (en) * | 2022-08-11 | 2024-06-11 | Hong Kong Chinese Medicine Ophthalmology Institute Limited | Traditional chinese medicine eye drops and the preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192535A (en) * | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| HU209538B (en) * | 1990-05-09 | 1994-07-28 | Vepex Contractor Ltd | Set and cleaning composition for treating contactlenses |
-
2000
- 2000-05-04 HU HU0001769A patent/HUP0001769A2/en unknown
-
2001
- 2001-05-04 CA CA002407794A patent/CA2407794A1/en not_active Abandoned
- 2001-05-04 EP EP01931980A patent/EP1278511B1/en not_active Expired - Lifetime
- 2001-05-04 WO PCT/HU2001/000053 patent/WO2001082893A1/en active IP Right Grant
- 2001-05-04 AT AT01931980T patent/ATE272389T1/en not_active IP Right Cessation
- 2001-05-04 US US10/275,125 patent/US6949241B2/en not_active Expired - Fee Related
- 2001-05-04 ES ES01931980T patent/ES2248326T3/en not_active Expired - Lifetime
- 2001-05-04 DE DE2001604670 patent/DE60104670T2/en not_active Expired - Lifetime
- 2001-05-04 AU AU2001258662A patent/AU2001258662A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0001769A2 (en) | 2002-01-28 |
| ES2248326T3 (en) | 2006-03-16 |
| EP1278511B1 (en) | 2004-08-04 |
| WO2001082893A1 (en) | 2001-11-08 |
| US6949241B2 (en) | 2005-09-27 |
| US20030124112A1 (en) | 2003-07-03 |
| HU0001769D0 (en) | 2000-07-28 |
| DE60104670D1 (en) | 2004-09-09 |
| ATE272389T1 (en) | 2004-08-15 |
| DE60104670T2 (en) | 2005-01-13 |
| CA2407794A1 (en) | 2001-11-08 |
| EP1278511A1 (en) | 2003-01-29 |
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