[go: up one dir, main page]

AU2001246494A1 - Condensed thiazolamines and their use as neuropeptide y5 antagonists - Google Patents

Condensed thiazolamines and their use as neuropeptide y5 antagonists

Info

Publication number
AU2001246494A1
AU2001246494A1 AU2001246494A AU4649401A AU2001246494A1 AU 2001246494 A1 AU2001246494 A1 AU 2001246494A1 AU 2001246494 A AU2001246494 A AU 2001246494A AU 4649401 A AU4649401 A AU 4649401A AU 2001246494 A1 AU2001246494 A1 AU 2001246494A1
Authority
AU
Australia
Prior art keywords
thiazolamines
neuropeptide
antagonists
condensed
condensed thiazolamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001246494A
Inventor
Marc Gerspacher
Heinrich Rueger
Tibur Schmidlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2001246494A1 publication Critical patent/AU2001246494A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539Five-membered rings
    • C07F9/6541Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001246494A 2000-03-03 2001-03-01 Condensed thiazolamines and their use as neuropeptide y5 antagonists Abandoned AU2001246494A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10010476 2000-03-03
DE10010475 2000-03-03
DE10010475 2000-03-03
DE10010476 2000-03-03
PCT/EP2001/002339 WO2001064675A1 (en) 2000-03-03 2001-03-01 Condensed thiazolamines and their use as neuropeptide y5 antagonists

Publications (1)

Publication Number Publication Date
AU2001246494A1 true AU2001246494A1 (en) 2001-09-12

Family

ID=26004675

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001246494A Abandoned AU2001246494A1 (en) 2000-03-03 2001-03-01 Condensed thiazolamines and their use as neuropeptide y5 antagonists

Country Status (2)

Country Link
AU (1) AU2001246494A1 (en)
WO (1) WO2001064675A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1183245E (en) 1999-04-22 2007-07-12 Lundbeck & Co As H Selective npy (y5) antagonists
US6989379B1 (en) 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists
US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
JP2003503486A (en) * 1999-06-30 2003-01-28 シナプティック・ファーマスーティカル・コーポレーション Selective NPY (Y5) antagonist
US7273880B2 (en) 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
ATE373654T1 (en) 2002-02-28 2007-10-15 Hoffmann La Roche THIAZOLE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS
ES2193875B2 (en) 2002-04-09 2005-03-01 Laboratorios Del Dr. Esteve, S.A. DERIVATIVES OF BENZOXAZINONA, ITS PREPARATION AND ITS APPLICATION AS MEDICATIONS.
AU2003253364B2 (en) * 2002-08-07 2007-06-07 F. Hoffmann-La Roche Ag Thiazole derivatives
RU2321586C2 (en) * 2003-08-12 2008-04-10 Ф.Хоффманн-Ля Рош Аг Derivatives of thiazole as npy antagonists
TWI443102B (en) 2008-03-31 2014-07-01 Genentech Inc Benzopyran and benzoxepin pi3k inhibitor compounds and methods of use
JP5642661B2 (en) * 2009-03-05 2014-12-17 塩野義製薬株式会社 Piperidine and pyrrolidine derivatives having NPYY5 receptor antagonistic activity
MY184074A (en) 2009-09-28 2021-03-17 Hoffmann La Roche Benzoxazepin p13k inhibitors compounds and methods of use
KR20140034948A (en) * 2009-09-28 2014-03-20 에프. 호프만-라 로슈 아게 Benzoxepin pi3k inhibitor compounds and methods of use
WO2012126901A1 (en) 2011-03-21 2012-09-27 F. Hoffmann-La Roche Ag Benzoxazepin compounds selective for pi3k p110 delta and methods of use
CN104284899A (en) 2012-02-17 2015-01-14 弗·哈夫曼-拉罗切有限公司 Tricyclic compounds and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19824175A1 (en) * 1998-05-29 1999-12-02 Novartis Ag Amino azole compounds
DE19908537A1 (en) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Use of polycyclic 2-amino-thiazole systems for the preparation of medicaments for the prophylaxis or treatment of obesity
JP2003503486A (en) * 1999-06-30 2003-01-28 シナプティック・ファーマスーティカル・コーポレーション Selective NPY (Y5) antagonist

Also Published As

Publication number Publication date
WO2001064675A1 (en) 2001-09-07

Similar Documents

Publication Publication Date Title
PT1317485E (en) Myostatin antagonists and uses thereof
TWI316062B (en) Anti-inflammatory compounds and uses thereof
AU2001294547A1 (en) Substituted urea neuropeptide y y5 receptor antagonists
HUP0500880A2 (en) Cxcr3 antagonists and pharmaceutical compositions thereof
HUP0301201A3 (en) Methods and compositions utilizing quinazolinones
AU2001294814A1 (en) Pumpcn compositions and uses thereof
AU2002235224A1 (en) Muscarinic antagonists
IL152700A0 (en) Substituted 1-aminoalkyl-lactams and their use as muscarinc receptor antagonists
IL156161A0 (en) Substituted 2-anilino-benzimidazoles and the use thereof as nhe-inhibitors
AU2001246494A1 (en) Condensed thiazolamines and their use as neuropeptide y5 antagonists
AU2001240637A1 (en) Novel imidazotriazinones and the use thereof
GB0101035D0 (en) Formulation and use thereof
AU2001234741A1 (en) Integrin antagonists
AU2001276461A1 (en) Cleaning compositions and their use
HK1043482A1 (en) Ceramic composition and ceramic capacitor.
HUP0401535A3 (en) Somatostatin antagonists and their use
HUP0300050A3 (en) Detergent composition and its use
HUP0303936A3 (en) Novel composition and use
AU2001276258A1 (en) Ceramic component and the use thereof
GB2379320B (en) Street furniture or the like
AU2000231564A1 (en) Phosphororganic compounds and the use thereof
AU2002224825A1 (en) Substituted amidoalkyl uracils and the use thereof
GB2364640B (en) Anti-ulcer pharmaceutical composition and the preparation thereof
AU2001239954A1 (en) Cleaning compositions and use thereof
AU2001277519A1 (en) Bio-probes and use thereof