AU2001228638A1 - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- AU2001228638A1 AU2001228638A1 AU2001228638A AU2863801A AU2001228638A1 AU 2001228638 A1 AU2001228638 A1 AU 2001228638A1 AU 2001228638 A AU2001228638 A AU 2001228638A AU 2863801 A AU2863801 A AU 2863801A AU 2001228638 A1 AU2001228638 A1 AU 2001228638A1
- Authority
- AU
- Australia
- Prior art keywords
- chemical compounds
- compounds
- chemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00400228 | 2000-01-28 | ||
| EP00400228 | 2000-01-28 | ||
| PCT/GB2001/000245 WO2001055116A2 (en) | 2000-01-28 | 2001-01-24 | Quinoline derivatives and their use as aurora 2 kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001228638A1 true AU2001228638A1 (en) | 2001-08-07 |
Family
ID=8173521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001228638A Abandoned AU2001228638A1 (en) | 2000-01-28 | 2001-01-24 | Chemical compounds |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6977259B2 (en) |
| EP (1) | EP1294709A2 (en) |
| JP (1) | JP2003520855A (en) |
| AU (1) | AU2001228638A1 (en) |
| WO (1) | WO2001055116A2 (en) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2272737T3 (en) | 2001-07-16 | 2007-05-01 | Astrazeneca Ab | DERIVATIVES OF QUINOLINA AND ITS USE AS INHIBITORS OF THYROSINE KINASES. |
| US6939874B2 (en) * | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
| US6797825B2 (en) | 2001-12-13 | 2004-09-28 | Abbott Laboratories | Protein kinase inhibitors |
| US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| US7560558B2 (en) * | 2002-08-23 | 2009-07-14 | Kirin Beer Kabushiki Kaisha | Compound having TGFβ inhibitory activity and medicinal composition containing the same |
| AU2013204031B2 (en) * | 2003-09-26 | 2016-10-27 | Exelixis, Inc. | c-Met modulators and methods of use |
| ES2925655T3 (en) * | 2003-09-26 | 2022-10-19 | Exelixis Inc | c-Met modulators and methods of use |
| EP1694686A1 (en) | 2003-12-19 | 2006-08-30 | Takeda San Diego, Inc. | Kinase inhibitors |
| TW200526219A (en) | 2004-01-16 | 2005-08-16 | Wyeth Corp | Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof |
| AU2005231507B2 (en) | 2004-04-08 | 2012-03-01 | Targegen, Inc. | Benzotriazine inhibitors of kinases |
| US20050250829A1 (en) * | 2004-04-23 | 2005-11-10 | Takeda San Diego, Inc. | Kinase inhibitors |
| EP1778669A2 (en) | 2004-08-18 | 2007-05-02 | Takeda San Diego, Inc. | Kinase inhibitors |
| AR050948A1 (en) | 2004-09-24 | 2006-12-06 | Hoffmann La Roche | DERIVATIVES OF FTALAZINONA; ITS OBTAINING AND ITS USE IN THE MANUFACTURE OF MEDICINES FOR THE TREATMENT OF CANCER. |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| BRPI0516093A (en) | 2004-10-12 | 2008-08-19 | Astrazeneca Ab | quinazoline derivative, process for preparing it, pharmaceutical composition, use of a quinazoline derivative, and method for treating cell proliferative disorders in a warm-blooded animal |
| DE602005023333D1 (en) | 2004-10-15 | 2010-10-14 | Takeda Pharmaceutical | KINASE INHIBITORS |
| KR20070113286A (en) | 2005-04-14 | 2007-11-28 | 에프. 호프만-라 로슈 아게 | Aminopyrazole Derivatives, Preparations thereof, and Uses as Pharmaceutical Formulations |
| GB0509224D0 (en) * | 2005-05-05 | 2005-06-15 | Chroma Therapeutics Ltd | Inhibitors of intracellular enzymatic activity |
| US8119655B2 (en) * | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| HUE028987T2 (en) | 2005-11-01 | 2017-01-30 | Targegen Inc | BI-aryl-meta-pyrimidine inhibitors of kinases |
| US20090076075A1 (en) * | 2006-03-02 | 2009-03-19 | Frederic Henri Jung | Quinoline derivatives |
| JP2009528338A (en) * | 2006-03-02 | 2009-08-06 | アストラゼネカ アクチボラグ | Quinoline derivatives for treating cancer |
| UY30183A1 (en) | 2006-03-02 | 2007-10-31 | Astrazeneca Ab | QUINOLINE DERIVATIVES |
| EP2223925A1 (en) * | 2006-10-09 | 2010-09-01 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| EA200970361A1 (en) | 2006-10-09 | 2010-02-26 | Такеда Фармасьютикал Компани Лимитед | KINASE INHIBITORS |
| KR20250123237A (en) | 2009-01-16 | 2025-08-14 | 엑셀리시스, 인코포레이티드 | Malate salt of n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer |
| UA108618C2 (en) | 2009-08-07 | 2015-05-25 | APPLICATION OF C-MET-MODULATORS IN COMBINATION WITH THEMOSOLOMID AND / OR RADIATION THERAPY FOR CANCER TREATMENT | |
| WO2012060847A1 (en) | 2010-11-07 | 2012-05-10 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| BR112013022307A2 (en) | 2011-03-04 | 2020-09-24 | Glaxosmithkline Intellectual Property (No. 2) Limited | aminoquinolines as kinase inhibitors |
| TWI547494B (en) | 2011-08-18 | 2016-09-01 | 葛蘭素史克智慧財產發展有限公司 | Aminoquinazolines as kinase inhibitors |
| CN103304489B (en) * | 2012-03-16 | 2015-03-11 | 中国农业科学院兰州畜牧与兽药研究所 | Pyrimidine benzamide compound and preparation and application thereof |
| AR092529A1 (en) | 2012-09-13 | 2015-04-22 | Glaxosmithkline Llc | AMINOQUINAZOLINE COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND USE OF THIS COMPOSITE FOR THE PREPARATION OF A MEDICINAL PRODUCT |
| AR092530A1 (en) | 2012-09-13 | 2015-04-22 | Glaxosmithkline Llc | AMINO-QUINOLINE COMPOSITE, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND USE OF THIS COMPOUND FOR THE PREPARATION OF A MEDICINAL PRODUCT |
| TWI630203B (en) | 2013-02-21 | 2018-07-21 | 葛蘭素史克智慧財產發展有限公司 | Quinazolines as kinase inhibitors |
| CN111808098B (en) * | 2020-06-29 | 2021-08-24 | Vtv治疗有限责任公司 | Quinoline derivatives, pharmaceutically acceptable salts thereof, and methods of use thereof |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3121720A (en) * | 1964-02-18 | I-substituted tetrahydro isoquevolines | ||
| FR2543E (en) * | 1901-09-23 | 1904-05-06 | Jules Heizmann | Apparatus or part of an apparatus for the exchange or transmission of heat between gaseous or liquid fluids and other substances |
| US3075981A (en) * | 1958-04-03 | 1963-01-29 | Sterling Drug Inc | 1-[aromatic-(lower-alkyl)]-4-(aromaticimino)-1, 4-dihydroquinolines and their preparation |
| ES299510A3 (en) * | 1964-04-28 | 1964-06-16 | Ind Iberica Quimico Farmaceuti | A procedure for the obtaining of (pyridil-2 ') amino-4 chlorine-7-quinolein (Machine-translation by Google Translate, not legally binding) |
| ES299684A3 (en) * | 1964-04-29 | 1964-07-01 | Ind Iberica Quimico Farmaceuti | A procedure for the obtaining of (methyl-4'-pyridil-2 ') amino-4-chlorine-7-quinolein (Machine-translation by Google Translate, not legally binding) |
| FR2154326A1 (en) * | 1971-09-30 | 1973-05-11 | Crt | (7' or 8' chloro-4-quinolinyl)-2-amino-nicotinic acid derivs - - analgesic,antiinflammatory |
| SG64322A1 (en) | 1991-05-10 | 1999-04-27 | Rhone Poulenc Rorer Int | Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
| US5710158A (en) * | 1991-05-10 | 1998-01-20 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
| JP2994165B2 (en) * | 1992-06-26 | 1999-12-27 | ゼネカ・リミテッド | Quinazoline derivative, method for producing the same, and pharmaceutical preparation containing the quinazoline derivative for obtaining anticancer activity |
| JPH0649062A (en) * | 1992-07-31 | 1994-02-22 | Mitsui Toatsu Chem Inc | Pyrimidinylamino or triazinylaminoquinoline derivatives, their production method and agricultural and horticultural fungicides containing the same |
| GB9510757D0 (en) | 1994-09-19 | 1995-07-19 | Wellcome Found | Therapeuticaly active compounds |
| US6143764A (en) | 1995-11-07 | 2000-11-07 | Kirin Beer Kabushiki Kaisha | Quinoline and quinazoline derivatives inhibiting platelet-derived growth factor receptor autophosphorylation and pharmaceutical compositions containing the same |
| RS49779B (en) * | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS |
| GB9800575D0 (en) * | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
| DK1244650T3 (en) | 1999-11-29 | 2003-10-20 | Aventis Pharma Sa | Arylamine derivatives and their use as antithelomerase agents |
-
2001
- 2001-01-24 AU AU2001228638A patent/AU2001228638A1/en not_active Abandoned
- 2001-01-24 JP JP2001555058A patent/JP2003520855A/en active Pending
- 2001-01-24 WO PCT/GB2001/000245 patent/WO2001055116A2/en not_active Ceased
- 2001-01-24 EP EP01946855A patent/EP1294709A2/en not_active Withdrawn
- 2001-01-24 US US10/182,454 patent/US6977259B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1294709A2 (en) | 2003-03-26 |
| US6977259B2 (en) | 2005-12-20 |
| WO2001055116A2 (en) | 2001-08-02 |
| JP2003520855A (en) | 2003-07-08 |
| WO2001055116A3 (en) | 2001-12-27 |
| US20030105129A1 (en) | 2003-06-05 |
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