AU1772099A - Modified deacetoxycephalosporin c synthase (daocs) and x-ray structure - Google Patents
Modified deacetoxycephalosporin c synthase (daocs) and x-ray structureInfo
- Publication number
- AU1772099A AU1772099A AU17720/99A AU1772099A AU1772099A AU 1772099 A AU1772099 A AU 1772099A AU 17720/99 A AU17720/99 A AU 17720/99A AU 1772099 A AU1772099 A AU 1772099A AU 1772099 A AU1772099 A AU 1772099A
- Authority
- AU
- Australia
- Prior art keywords
- daocs
- deacetoxycephalosporin
- synthase
- modified
- ray structure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108030001962 Deacetoxycephalosporin-C synthases Proteins 0.000 title 1
- NNQIJOYQWYKBOW-VMAXQDLPSA-N deacetoxycephalosporin-c Chemical class S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](NC(=O)CCC[C@H](N)C(O)=O)[C@H]12 NNQIJOYQWYKBOW-VMAXQDLPSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Biotechnology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9727370.0A GB9727370D0 (en) | 1997-12-24 | 1997-12-24 | Processed based on the structure of deacetoxycephalosporin c synthase |
| GB9727370 | 1997-12-24 | ||
| GBGB9813644.3A GB9813644D0 (en) | 1998-06-24 | 1998-06-24 | Structure of a cephalosporin synthase |
| GB9813644 | 1998-06-24 | ||
| PCT/GB1998/003860 WO1999033994A1 (en) | 1997-12-24 | 1998-12-24 | Modified deacetoxycephalosporin c synthase (daocs) and x-ray structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1772099A true AU1772099A (en) | 1999-07-19 |
Family
ID=26312856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU17720/99A Abandoned AU1772099A (en) | 1997-12-24 | 1998-12-24 | Modified deacetoxycephalosporin c synthase (daocs) and x-ray structure |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1047785A1 (en) |
| JP (1) | JP2002500015A (en) |
| CN (1) | CN1284997A (en) |
| AU (1) | AU1772099A (en) |
| CA (1) | CA2316401A1 (en) |
| PL (1) | PL341396A1 (en) |
| SK (1) | SK9762000A3 (en) |
| WO (1) | WO1999033994A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0011185D0 (en) * | 2000-05-09 | 2000-06-28 | Synpac Pharmaceuticals Limited | Protein |
| US6699699B2 (en) * | 2002-03-26 | 2004-03-02 | Synmax Biochemical Co., Ltd. | Mutated penicillin expandases |
| EP2802661B1 (en) * | 2012-01-10 | 2017-07-19 | Orchid Chemicals and Pharmaceuticals Ltd | Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis |
| CN114958877B (en) * | 2022-06-14 | 2024-02-20 | 河南省健康元生物医药研究院有限公司 | Deacetylated oxo cephalosporin C synthetase mutant, encoding gene and application thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5082772A (en) * | 1988-10-24 | 1992-01-21 | Eli Lilly And Company | Process for preparing deacetylcephalosporin c |
| US5318896A (en) * | 1991-09-11 | 1994-06-07 | Merck & Co., Inc. | Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA) |
| US5919680A (en) * | 1995-11-27 | 1999-07-06 | Isis Innovation Limited | Process for the production of SSC's via expandase activity on penicillin G |
| GB9621486D0 (en) * | 1996-10-15 | 1996-12-04 | Isis Innovation | Oxygenase enzymes & method |
-
1998
- 1998-12-24 EP EP98962587A patent/EP1047785A1/en not_active Withdrawn
- 1998-12-24 CA CA002316401A patent/CA2316401A1/en not_active Abandoned
- 1998-12-24 PL PL98341396A patent/PL341396A1/en unknown
- 1998-12-24 CN CN98813793A patent/CN1284997A/en active Pending
- 1998-12-24 SK SK976-2000A patent/SK9762000A3/en unknown
- 1998-12-24 AU AU17720/99A patent/AU1772099A/en not_active Abandoned
- 1998-12-24 WO PCT/GB1998/003860 patent/WO1999033994A1/en not_active Application Discontinuation
- 1998-12-24 JP JP2000526650A patent/JP2002500015A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| SK9762000A3 (en) | 2001-02-12 |
| EP1047785A1 (en) | 2000-11-02 |
| CA2316401A1 (en) | 1999-07-08 |
| WO1999033994A1 (en) | 1999-07-08 |
| CN1284997A (en) | 2001-02-21 |
| JP2002500015A (en) | 2002-01-08 |
| PL341396A1 (en) | 2001-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |