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AU1638801A - Pharmaceutical composition in the form of a nucleic acid lipid complex, the production thereof and its use in gene therapy - Google Patents

Pharmaceutical composition in the form of a nucleic acid lipid complex, the production thereof and its use in gene therapy

Info

Publication number
AU1638801A
AU1638801A AU16388/01A AU1638801A AU1638801A AU 1638801 A AU1638801 A AU 1638801A AU 16388/01 A AU16388/01 A AU 16388/01A AU 1638801 A AU1638801 A AU 1638801A AU 1638801 A AU1638801 A AU 1638801A
Authority
AU
Australia
Prior art keywords
production
nucleic acid
pharmaceutical composition
gene therapy
lipid complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU16388/01A
Inventor
Jens Schletter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CARDION AG
Original Assignee
Cardiogene Gentherapeutische Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiogene Gentherapeutische Systeme AG filed Critical Cardiogene Gentherapeutische Systeme AG
Publication of AU1638801A publication Critical patent/AU1638801A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU16388/01A 1999-09-15 2000-09-14 Pharmaceutical composition in the form of a nucleic acid lipid complex, the production thereof and its use in gene therapy Abandoned AU1638801A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19944262 1999-09-15
DE1999144262 DE19944262A1 (en) 1999-09-15 1999-09-15 Pharmaceutical composition in the form of a nucleic acid-lipid complex, its production and use in gene therapy
PCT/EP2000/008996 WO2001019400A2 (en) 1999-09-15 2000-09-14 Pharmaceutical composition in the form of a nucleic acid lipid complex, the production thereof and its use in gene therapy

Publications (1)

Publication Number Publication Date
AU1638801A true AU1638801A (en) 2001-04-17

Family

ID=7922150

Family Applications (1)

Application Number Title Priority Date Filing Date
AU16388/01A Abandoned AU1638801A (en) 1999-09-15 2000-09-14 Pharmaceutical composition in the form of a nucleic acid lipid complex, the production thereof and its use in gene therapy

Country Status (4)

Country Link
EP (1) EP1216027A2 (en)
AU (1) AU1638801A (en)
DE (1) DE19944262A1 (en)
WO (1) WO2001019400A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1512393A1 (en) * 2003-09-08 2005-03-09 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Process for the production of homogeneous liposomes and lipoplexes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658565A (en) * 1994-06-24 1997-08-19 University Of Pittsburgh Of The Commonwealth System Of Higher Education Inducible nitric oxide synthase gene for treatment of disease
DE4411402A1 (en) * 1994-03-31 1995-10-05 Juergen Schrader DNA expression vectors for use in gene therapy treatment of vascular diseases
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
EP0748332B1 (en) * 1994-12-28 1999-11-10 Max-Delbrück-Centrum Für Molekulare Medizin New cholesterol derivative for liposomal gene transfer
US5660855A (en) * 1995-02-10 1997-08-26 California Institute Of Technology Lipid constructs for targeting to vascular smooth muscle tissue
WO1996027393A1 (en) * 1995-03-07 1996-09-12 University Of Pittsburgh A dry powder formulation for gene therapy
CA2214029A1 (en) * 1995-04-25 1996-10-31 Magda Marquet Single-vial formulations of dna/lipid complexes
EP0833667A4 (en) * 1995-06-07 2001-11-21 Univ California STABILIZATION OF POLYNUCLEOTIDE COMPLEXES
ES2231819T3 (en) * 1995-06-07 2005-05-16 Inex Pharmaceuticals Corp PARTICULES OF NUCLEIC LIPIDO-ACID PREPARED THROUGH A NIPLEIC HYDROPHOBIC NIPLEIC ACID COMPLEX INTERMEDIATE AND USE TO TRANSFER GENES.
US5753262A (en) * 1995-06-07 1998-05-19 Aronex Pharmaceuticals, Inc. Cationic lipid acid salt of 3beta N- (N', N'-dimethylaminoethane) - carbamoyl!cholestrol and halogenated solvent-free preliposomal lyophilate thereof
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes
US6271208B1 (en) * 1996-08-26 2001-08-07 Transgene S.A. Process of making cationic lipid-nucleic acid complexes
AU6957198A (en) * 1997-04-07 1998-10-30 Rutgers, The State University Of New Jersey Cytokine and cisplatin-based gene therapy of carcinomas
DE19729769A1 (en) * 1997-07-11 1999-01-14 Cardiogene Gentherapeutische S Transfection system, its manufacture and use in somatic gene therapy

Also Published As

Publication number Publication date
WO2001019400A3 (en) 2002-02-14
DE19944262A1 (en) 2001-03-29
WO2001019400A2 (en) 2001-03-22
EP1216027A2 (en) 2002-06-26

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase