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AU1599301A - Modulating IL-13 activity using mutated IL-13 molecules that are antagonists or agonists of IL-13 - Google Patents

Modulating IL-13 activity using mutated IL-13 molecules that are antagonists or agonists of IL-13

Info

Publication number
AU1599301A
AU1599301A AU15993/01A AU1599301A AU1599301A AU 1599301 A AU1599301 A AU 1599301A AU 15993/01 A AU15993/01 A AU 15993/01A AU 1599301 A AU1599301 A AU 1599301A AU 1599301 A AU1599301 A AU 1599301A
Authority
AU
Australia
Prior art keywords
mutated
agonists
antagonists
modulating
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU15993/01A
Inventor
Bharat H. Joshi
Yasuo Oshima
Raj K Puri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of AU1599301A publication Critical patent/AU1599301A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5437—IL-13
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU15993/01A 1999-11-11 2000-11-10 Modulating IL-13 activity using mutated IL-13 molecules that are antagonists or agonists of IL-13 Abandoned AU1599301A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16523699P 1999-11-11 1999-11-11
US60165236 1999-11-11
PCT/US2000/031044 WO2001034645A2 (en) 1999-11-11 2000-11-10 Mutated il-13 molecules and their uses

Publications (1)

Publication Number Publication Date
AU1599301A true AU1599301A (en) 2001-06-06

Family

ID=22598038

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15993/01A Abandoned AU1599301A (en) 1999-11-11 2000-11-10 Modulating IL-13 activity using mutated IL-13 molecules that are antagonists or agonists of IL-13

Country Status (4)

Country Link
EP (1) EP1263785A2 (en)
AU (1) AU1599301A (en)
CA (1) CA2404763A1 (en)
WO (1) WO2001034645A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010053371A1 (en) * 1999-01-07 2001-12-20 Waldemar Debinski Method for diagnosing, imaging, and treating tumors using restrictive receptor for interleukin 13
DE60142479D1 (en) * 2000-08-30 2010-08-12 Penn State Res Found AMINO ACID EXCHANGE MUTANTS OF INTERLEUKIN 13
GB0105360D0 (en) * 2001-03-03 2001-04-18 Glaxo Group Ltd Chimaeric immunogens
WO2003016346A1 (en) * 2001-08-17 2003-02-27 Hitachi Chemical Co., Ltd. Ligands
AR041086A1 (en) * 2002-08-30 2005-04-27 Glaxo Group Ltd VACCINE
CA2496948A1 (en) * 2002-08-30 2004-03-11 Glaxo Group Limited Il-14 vaccine for the treatment of asthma and atopic disorders
WO2005052006A2 (en) 2003-11-25 2005-06-09 The Government Of The United States, As Represented By The Secretary Of Health And Human Services Mutated anti-cd22 antibodies and immunoconjugates
PT2805728T (en) 2003-12-23 2020-04-08 Genentech Inc Novel anti-il 13 antibodies and uses thereof
EP1877074B1 (en) 2005-04-15 2013-03-27 The Government of the United States of America, as represented by the Secretary of Health and Human Services Treatment and prevention of inflammatory bowel disease involving il-13 and nkt cells
PL3006457T3 (en) 2005-07-29 2018-05-30 The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services Mutated pseudomonas exotoxins with reduced antigenicity
WO2011032022A1 (en) 2009-09-11 2011-03-17 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Improved pseudomonas exotoxin a with reduced immunogenicity
EP2850093B1 (en) 2012-01-27 2019-01-09 The Board of Trustees of the Leland Stanford Junior University Therapeutic il-13 polypeptides
IN2015KN00329A (en) 2012-08-09 2015-07-10 Univ Leland Stanford Junior
NZ756750A (en) 2013-09-13 2022-05-27 Genentech Inc Methods and compositions comprising purified recombinant polypeptides
CA3174012A1 (en) 2013-09-13 2015-03-19 Genentech, Inc. Compositions and methods for detecting and quantifying host cell protein in cell lines and recombinant polypeptide products
WO2015042706A1 (en) 2013-09-24 2015-04-02 Medicenna Therapeutics Pte Ltd Interleukin-4 receptor-binding fusion proteins and uses thereof
JP6737788B2 (en) * 2014-09-09 2020-08-12 グリコシン リミテッド ライアビリティー カンパニー Α(1,3)fucosyltransferase for use in the production of fucosylated oligosaccharides
JP7095990B2 (en) * 2014-09-18 2022-07-05 シーダーズ－サイナイ メディカル センター Compositions and Methods for Treating Fibrosis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696234A (en) * 1994-08-01 1997-12-09 Schering Corporation Muteins of mammalian cytokine interleukin-13
US5614191A (en) * 1995-03-15 1997-03-25 The United States Of America As Represented By The Department Of Health And Human Services IL-13 receptor specific chimeric proteins and uses thereof
US5710023A (en) * 1996-03-01 1998-01-20 Genetics Institute, Inc. IL-13 cytokine receptor chain
US6296843B1 (en) * 1998-04-03 2001-10-02 The Penn State Research Foundation Mutagenized IL 13-based chimeric molecules
EP1222212A4 (en) * 1999-10-06 2005-05-04 Penn State Res Found Il13 mutants

Also Published As

Publication number Publication date
WO2001034645A2 (en) 2001-05-17
CA2404763A1 (en) 2001-05-17
EP1263785A2 (en) 2002-12-11
WO2001034645A3 (en) 2002-03-07

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase