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AU1589895A - Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors - Google Patents

Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors

Info

Publication number
AU1589895A
AU1589895A AU15898/95A AU1589895A AU1589895A AU 1589895 A AU1589895 A AU 1589895A AU 15898/95 A AU15898/95 A AU 15898/95A AU 1589895 A AU1589895 A AU 1589895A AU 1589895 A AU1589895 A AU 1589895A
Authority
AU
Australia
Prior art keywords
optically active
synthase inhibitors
derivatives useful
squalene synthase
benzoxazepine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU15898/95A
Inventor
Kazuaki Kitano
Masakuni Kori
Ryuichi Tozawa
Hidefumi Yukimasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of AU1589895A publication Critical patent/AU1589895A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU15898/95A 1994-02-09 1995-02-06 Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors Abandoned AU1589895A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6-15531 1994-02-09
JP1553194 1994-02-09
PCT/JP1995/000148 WO1995021834A1 (en) 1994-02-09 1995-02-06 Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors

Publications (1)

Publication Number Publication Date
AU1589895A true AU1589895A (en) 1995-08-29

Family

ID=11891401

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15898/95A Abandoned AU1589895A (en) 1994-02-09 1995-02-06 Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors

Country Status (2)

Country Link
AU (1) AU1589895A (en)
WO (1) WO1995021834A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726306A (en) * 1992-04-20 1998-03-10 Takeda Chemical Industries, Ltd. 4,1-benzoxazepin derivatives and their use
TW401301B (en) * 1994-10-07 2000-08-11 Takeda Chemical Industries Ltd Antihypertriglyceridemic composition
CA2161849A1 (en) * 1994-11-01 1996-05-02 Kazuo Nakahama Production of optically active compounds
CA2231052C (en) * 1995-09-13 2007-11-13 Takeda Chemical Industries, Ltd. Benzoxazepine compounds, their production and use as lipid lowering agents
AU6944296A (en) * 1995-09-13 1997-04-01 Takeda Chemical Industries Ltd. Benzoxazepine compounds, their production and use as lipid lowering agents
US5965553A (en) * 1996-06-20 1999-10-12 Pfizer Inc. Squalene synthetase inhibitors
US20040204500A1 (en) * 2001-06-28 2004-10-14 Yasuo Sugiyama Preventives/remedies for organ functional disorders and organ dysfunction

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69332792T2 (en) * 1992-04-20 2004-01-15 Takeda Chemical Industries Ltd 4,1-Benzoxazepine derivatives as squalene synthetase inhibitors and their use for the treatment of hypercholesteremia and as fungicides

Also Published As

Publication number Publication date
WO1995021834A1 (en) 1995-08-17

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