AU1252099A - Improved selex procedure and an anti-cd4 aptamer - Google Patents
Improved selex procedure and an anti-cd4 aptamerInfo
- Publication number
- AU1252099A AU1252099A AU12520/99A AU1252099A AU1252099A AU 1252099 A AU1252099 A AU 1252099A AU 12520/99 A AU12520/99 A AU 12520/99A AU 1252099 A AU1252099 A AU 1252099A AU 1252099 A AU1252099 A AU 1252099A
- Authority
- AU
- Australia
- Prior art keywords
- aptamer
- selex procedure
- improved selex
- improved
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9725024 | 1997-11-26 | ||
| GBGB9725024.5A GB9725024D0 (en) | 1997-11-26 | 1997-11-26 | Procedure |
| US7822198P | 1998-03-16 | 1998-03-16 | |
| US60078221 | 1998-03-16 | ||
| PCT/GB1998/003544 WO1999027133A1 (en) | 1997-11-26 | 1998-11-26 | Improved selex procedure and an anti-cd4 aptamer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1252099A true AU1252099A (en) | 1999-06-15 |
Family
ID=26312662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU12520/99A Abandoned AU1252099A (en) | 1997-11-26 | 1998-11-26 | Improved selex procedure and an anti-cd4 aptamer |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU1252099A (en) |
| WO (1) | WO1999027133A1 (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9809776D0 (en) * | 1998-05-07 | 1998-07-08 | Nycomed Imaging As | Method |
| GB9809780D0 (en) * | 1998-05-07 | 1998-07-08 | Nycomed Imaging As | Method |
| EP1330544A4 (en) * | 2000-09-26 | 2005-04-06 | Univ Duke | RNA APTAMERS AND METHOD OF IDENTIFYING THEM |
| AU2002225234A1 (en) * | 2001-01-29 | 2002-08-12 | Isis Innovation Limited | Streptavidin aptamere |
| AU2002226584A1 (en) * | 2001-01-29 | 2002-08-12 | Isis Innovation Limited | Immobilised aptamers |
| WO2006042112A2 (en) | 2004-10-05 | 2006-04-20 | California Institute Of Technology | Aptamer regulated nucleic acids and uses thereof |
| WO2007053358A2 (en) | 2005-10-28 | 2007-05-10 | Praecis Pharmaceuticals, Inc. | Methods for identifying compounds of interest using encoded libraries |
| US7964356B2 (en) | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| KR101656240B1 (en) | 2007-07-17 | 2016-09-09 | 소마로직, 인크. | Multiplexed analyses of test samples |
| WO2009012263A2 (en) | 2007-07-18 | 2009-01-22 | The Trustees Of Columbia University In The City Of New York | Tissue-specific micrornas and compositions and uses thereof |
| US20120165387A1 (en) | 2007-08-28 | 2012-06-28 | Smolke Christina D | General composition framework for ligand-controlled RNA regulatory systems |
| US8865667B2 (en) | 2007-09-12 | 2014-10-21 | California Institute Of Technology | Higher-order cellular information processing devices |
| US9029524B2 (en) | 2007-12-10 | 2015-05-12 | California Institute Of Technology | Signal activated RNA interference |
| US9599591B2 (en) | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
| US9145555B2 (en) | 2009-04-02 | 2015-09-29 | California Institute Of Technology | Integrated—ligand-responsive microRNAs |
| WO2011127933A1 (en) | 2010-04-16 | 2011-10-20 | Nuevolution A/S | Bi-functional complexes and methods for making and using such complexes |
| US20130195757A1 (en) * | 2010-04-30 | 2013-08-01 | Abraxis Bioscience, Llc | Sparc binding aptamers and uses thereof |
| ES2776029T3 (en) | 2012-10-08 | 2020-07-28 | St Jude Childrens Res Hospital | Therapies based on the control of the stability and function of regulatory T cells by means of a neuropilin-1 axis: semaphorin |
| EP3155101B1 (en) | 2014-06-16 | 2020-01-29 | The Johns Hopkins University | Compositions and methods for the expression of crispr guide rnas using the h1 promoter |
| EP3289104B1 (en) | 2015-04-29 | 2020-11-04 | New York University | Method for treating high-grade gliomas |
| EP3405577B8 (en) | 2016-01-20 | 2023-02-15 | 396419 B.C. Ltd. | Compositions and methods for inhibiting factor d |
| CN105777890A (en) * | 2016-04-17 | 2016-07-20 | 孟繁好 | Application of aptamer used for detecting protein GAT-1 in preparation of kit used for detecting anesthetic tolerance individuals |
| WO2018136827A1 (en) | 2017-01-20 | 2018-07-26 | Vitrisa Therapeutics, Inc. | Stem-loop compositions and methods for inhibiting factor d |
| CN109468326A (en) * | 2018-07-02 | 2019-03-15 | 广西医科大学 | A kind of CD4+T nucleic acid aptamer and its application |
| BR112022013589A2 (en) | 2020-01-08 | 2022-09-13 | Regeneron Pharma | TREATMENT OF PROGRESSIVE OSSIFYING FIBRODYSPLASIA |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635615A (en) * | 1990-06-11 | 1997-06-03 | Nexstar Pharmaceuticals, Inc. | High affinity HIV nucleocapsid nucleic acid ligands |
| US5869641A (en) * | 1990-06-11 | 1999-02-09 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands of CD4 |
| US5861254A (en) * | 1997-01-31 | 1999-01-19 | Nexstar Pharmaceuticals, Inc. | Flow cell SELEX |
| AU6260696A (en) * | 1995-06-07 | 1996-12-30 | Becton Dickinson & Company | High affinity oligonucleotide ligands to chorionic gonadotropin hormone and related glycoprotein hormones |
-
1998
- 1998-11-26 AU AU12520/99A patent/AU1252099A/en not_active Abandoned
- 1998-11-26 WO PCT/GB1998/003544 patent/WO1999027133A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999027133A1 (en) | 1999-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |