ATE96326T1 - Hemmung der in-vitro-infektivitaet und des zytopathischen effektes von htlv-iii/lav durch 2'3'-dideoxycytidin. - Google Patents
Hemmung der in-vitro-infektivitaet und des zytopathischen effektes von htlv-iii/lav durch 2'3'-dideoxycytidin.Info
- Publication number
- ATE96326T1 ATE96326T1 AT86306495T AT86306495T ATE96326T1 AT E96326 T1 ATE96326 T1 AT E96326T1 AT 86306495 T AT86306495 T AT 86306495T AT 86306495 T AT86306495 T AT 86306495T AT E96326 T1 ATE96326 T1 AT E96326T1
- Authority
- AT
- Austria
- Prior art keywords
- htlv
- iii
- dideoxycytidin
- lav
- inhibition
- Prior art date
Links
- 230000000120 cytopathologic effect Effects 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 2
- WREGKURFCTUGRC-POYBYMJQSA-N Zalcitabine Chemical compound O=C1N=C(N)C=CN1[C@@H]1O[C@H](CO)CC1 WREGKURFCTUGRC-POYBYMJQSA-N 0.000 abstract 1
- 239000001226 triphosphate Substances 0.000 abstract 1
- 235000011178 triphosphate Nutrition 0.000 abstract 1
- 125000002264 triphosphate group Chemical class [H]OP(=O)(O[H])OP(=O)(O[H])OP(=O)(O[H])O* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76901785A | 1985-08-26 | 1985-08-26 | |
| EP86306495A EP0216511B1 (de) | 1985-08-26 | 1986-08-21 | Hemmung der In-vitro-Infektivität und des zytopathischen Effektes von HTLV-III/LAV durch 2'3'-Dideoxycytidin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE96326T1 true ATE96326T1 (de) | 1993-11-15 |
Family
ID=25084170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86306495T ATE96326T1 (de) | 1985-08-26 | 1986-08-21 | Hemmung der in-vitro-infektivitaet und des zytopathischen effektes von htlv-iii/lav durch 2'3'-dideoxycytidin. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0216511B1 (de) |
| JP (1) | JPS62501777A (de) |
| AT (1) | ATE96326T1 (de) |
| AU (1) | AU570855B2 (de) |
| CA (1) | CA1277915C (de) |
| DE (1) | DE3689221T2 (de) |
| HK (1) | HK67995A (de) |
| IE (1) | IE63001B1 (de) |
| IL (1) | IL79699A (de) |
| NL (1) | NL940019I2 (de) |
| NZ (1) | NZ217184A (de) |
| WO (1) | WO1987001283A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR960001372B1 (ko) * | 1986-09-24 | 1996-01-26 | 예일 유니버시티 | 레트로비루스로 감염된 환자의 치료에 사용되는 2',3'-디디옥시사이티딘-2'-엔(2',3'-디디옥시-2',3'-디디하이드로사이티딘)의 항생물질 |
| IL86007A0 (en) * | 1987-04-09 | 1988-09-30 | Wellcome Found | 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them |
| GB8712691D0 (en) * | 1987-05-29 | 1987-07-01 | Wellcome Found | Therapeutic nucleosides |
| IL86009A (en) * | 1987-04-10 | 1991-09-16 | Us Health | Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases |
| EP0294113A1 (de) * | 1987-05-29 | 1988-12-07 | The Wellcome Foundation Limited | Therapeutische Nucleoside |
| JP2648329B2 (ja) * | 1987-09-18 | 1997-08-27 | エフ・ホフマン−ラ ロシュ アーゲー | エイズの予防または治療用医薬組成物 |
| US5028595A (en) * | 1987-09-18 | 1991-07-02 | Hoffmann-La Roche Inc. | Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus |
| WO1989002733A1 (en) * | 1987-09-22 | 1989-04-06 | The Regents Of The University Of California | Liposomal nucleoside analogues for treating aids |
| JPH04501854A (ja) * | 1989-05-15 | 1992-04-02 | アメリカ合衆国 | 肝炎の治療方法 |
| US5071983A (en) * | 1989-10-06 | 1991-12-10 | Burroughs Wellcome Co. | Therapeutic nucleosides |
| US5192749A (en) * | 1990-05-21 | 1993-03-09 | Syntex (U.S.A.) Inc. | 4'-substituted nucleosides |
| CA2270600A1 (en) | 1999-05-03 | 2000-11-03 | Infectio Recherche Inc. | Method and formulations for the treatment of diseases, particularly those caused by human immunodeficiency virus and leishmania |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT82580B (pt) * | 1985-05-15 | 1989-01-17 | Wellcome Found | Processo para a preparacao de 2',3'- didesoxinucleosidos e de composicoes farmaceuticas que os contem |
-
1986
- 1986-08-08 WO PCT/US1986/001626 patent/WO1987001283A1/en unknown
- 1986-08-08 JP JP61504539A patent/JPS62501777A/ja active Granted
- 1986-08-08 AU AU62843/86A patent/AU570855B2/en not_active Expired
- 1986-08-12 IL IL79699A patent/IL79699A/xx not_active IP Right Cessation
- 1986-08-13 NZ NZ217184A patent/NZ217184A/xx unknown
- 1986-08-14 CA CA000515943A patent/CA1277915C/en not_active Expired - Lifetime
- 1986-08-21 EP EP86306495A patent/EP0216511B1/de not_active Expired - Lifetime
- 1986-08-21 DE DE86306495T patent/DE3689221T2/de not_active Expired - Lifetime
- 1986-08-21 AT AT86306495T patent/ATE96326T1/de active
- 1986-08-25 IE IE226486A patent/IE63001B1/en not_active IP Right Cessation
-
1994
- 1994-10-17 NL NL940019C patent/NL940019I2/nl unknown
-
1995
- 1995-05-04 HK HK67995A patent/HK67995A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NL940019I1 (nl) | 1994-12-01 |
| JPH0215524B2 (de) | 1990-04-12 |
| DE3689221D1 (de) | 1993-12-02 |
| NZ217184A (en) | 1990-03-27 |
| AU6284386A (en) | 1987-03-24 |
| AU570855B2 (en) | 1988-03-24 |
| EP0216511A3 (en) | 1989-08-02 |
| EP0216511A2 (de) | 1987-04-01 |
| IE63001B1 (en) | 1995-03-08 |
| WO1987001283A1 (en) | 1987-03-12 |
| EP0216511B1 (de) | 1993-10-27 |
| JPS62501777A (ja) | 1987-07-16 |
| IL79699A (en) | 1992-07-15 |
| IL79699A0 (en) | 1986-11-30 |
| HK67995A (en) | 1995-05-12 |
| DE3689221T2 (de) | 1994-02-24 |
| CA1277915C (en) | 1990-12-18 |
| IE862264L (en) | 1987-02-26 |
| NL940019I2 (nl) | 1997-07-01 |
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