ATE7602T1 - Beta-d-arabinofuranosylimidazo(4,5-c)pyridinderivate und verfahren zu ihrer herstellung. - Google Patents
Beta-d-arabinofuranosylimidazo(4,5-c)pyridinderivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE7602T1 ATE7602T1 AT81303067T AT81303067T ATE7602T1 AT E7602 T1 ATE7602 T1 AT E7602T1 AT 81303067 T AT81303067 T AT 81303067T AT 81303067 T AT81303067 T AT 81303067T AT E7602 T1 ATE7602 T1 AT E7602T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- arabinofuranosylimidazo
- production
- pyridine derivatives
- arabinofuranosyl
- Prior art date
Links
- VWFARCSLIFAOQI-DOLQZWNJSA-N O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1C1=NC2=CN=CC=C2N1 Chemical class O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1C1=NC2=CN=CC=C2N1 VWFARCSLIFAOQI-DOLQZWNJSA-N 0.000 title 1
- -1 Hydroxy, amino Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 101710169336 5'-deoxyadenosine deaminase Proteins 0.000 abstract 1
- 102000055025 Adenosine deaminases Human genes 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/166,867 US4315000A (en) | 1980-07-07 | 1980-07-07 | β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production |
| EP81303067A EP0043722B1 (de) | 1980-07-07 | 1981-07-06 | Beta-D-arabinofuranosylimidazo(4,5-c)pyridin-Derivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE7602T1 true ATE7602T1 (de) | 1984-06-15 |
Family
ID=22605000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81303067T ATE7602T1 (de) | 1980-07-07 | 1981-07-06 | Beta-d-arabinofuranosylimidazo(4,5-c)pyridinderivate und verfahren zu ihrer herstellung. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4315000A (de) |
| EP (1) | EP0043722B1 (de) |
| JP (1) | JPS5746999A (de) |
| AT (1) | ATE7602T1 (de) |
| DE (1) | DE3163746D1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4388308A (en) * | 1980-06-09 | 1983-06-14 | G.D. Searle & Co. | N6 -[(2-Hydroxypropyl)aryl]adenosines |
| US4386093A (en) * | 1981-09-16 | 1983-05-31 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | (±)3-Deazaaristeromycin and uses |
| US4387228A (en) * | 1981-09-16 | 1983-06-07 | Southern Research Institute | Process for the production of (±)3-deazaaristeromycin |
| JPS5977900U (ja) * | 1982-11-17 | 1984-05-26 | 株式会社フジワラテクノアート | 通気式製麹機における品温自動測定装置 |
| DE3739366A1 (de) * | 1987-04-10 | 1988-10-27 | Boehringer Mannheim Gmbh | Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel |
| US6211158B1 (en) | 1987-04-10 | 2001-04-03 | Roche Diagnostics Gmbh | Desazapurine-nucleotide derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof for nucleic acid sequencing and as antiviral agents |
| JPH0199586U (de) * | 1987-12-21 | 1989-07-04 | ||
| DE3924424A1 (de) * | 1989-07-24 | 1991-01-31 | Boehringer Mannheim Gmbh | Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung |
| GEP20053601B (en) | 2001-01-22 | 2005-08-10 | Merck & Co Inc | Nucleoside Derivatives as Inhibitors of RNA-Dependent RNA Viral Polymerase |
| US6914052B2 (en) | 2001-03-15 | 2005-07-05 | The Trustees Of Boston College | Selective anti-viral nucleoside chain terminators |
| WO2012099630A1 (en) * | 2011-01-20 | 2012-07-26 | University Of Rochester | Compositions and methods for treating or preventing a retrovirus infection |
| US8846657B2 (en) * | 2012-12-20 | 2014-09-30 | Merck Sharp & Dohme Corp. | Substituted imidazopyridines as HDM2 inhibitors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3501456A (en) * | 1967-08-08 | 1970-03-17 | Merck & Co Inc | Arabinofuranosyl nucleosides and intermediates |
| US3472838A (en) * | 1967-12-01 | 1969-10-14 | Parke Davis & Co | 9 - (beta - d - arabinofuranosyl) - 6 - (amidino) purine compounds and methods for their production |
| US3651045A (en) * | 1968-10-21 | 1972-03-21 | Parke Davis & Co | 9-(beta-d-arabinofuranosyl)adenine esters and methods for their production |
| BE756704A (fr) * | 1969-09-26 | 1971-03-01 | Parke Davis & Co | Procede de production du 5'-phosphate de 9-(beta-d- arabinofuranosyl) adenine et de ses sels |
| US4056674A (en) * | 1973-07-06 | 1977-11-01 | Icn Pharmaceuticals, Inc. | Derivatives of 3-deazaguanine |
| US4055717A (en) * | 1976-05-17 | 1977-10-25 | Parke, Davis & Company | 9-(3-O-Acyl-β-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)-adenine compounds, and method for their production |
| US4048432A (en) * | 1976-05-17 | 1977-09-13 | Parke, Davis & Company | 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production |
| US4069382A (en) * | 1976-05-17 | 1978-01-17 | Parke, Davis & Company | 9-(5-O-Acyl-β-D-arabinofuranosyl)adenine compounds |
-
1980
- 1980-07-07 US US06/166,867 patent/US4315000A/en not_active Expired - Lifetime
-
1981
- 1981-07-06 EP EP81303067A patent/EP0043722B1/de not_active Expired
- 1981-07-06 AT AT81303067T patent/ATE7602T1/de not_active IP Right Cessation
- 1981-07-06 DE DE8181303067T patent/DE3163746D1/de not_active Expired
- 1981-07-07 JP JP56106828A patent/JPS5746999A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0043722B1 (de) | 1984-05-23 |
| JPS5746999A (en) | 1982-03-17 |
| DE3163746D1 (en) | 1984-06-28 |
| EP0043722A1 (de) | 1982-01-13 |
| US4315000A (en) | 1982-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |