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ATE71521T1 - Einrichtungen fuer die kontrollierte abgabe von aktiven substanzen und verfahren zu ihrer herstellung. - Google Patents

Einrichtungen fuer die kontrollierte abgabe von aktiven substanzen und verfahren zu ihrer herstellung.

Info

Publication number
ATE71521T1
ATE71521T1 AT86200384T AT86200384T ATE71521T1 AT E71521 T1 ATE71521 T1 AT E71521T1 AT 86200384 T AT86200384 T AT 86200384T AT 86200384 T AT86200384 T AT 86200384T AT E71521 T1 ATE71521 T1 AT E71521T1
Authority
AT
Austria
Prior art keywords
granulates
devices
phase
manufacture
processes
Prior art date
Application number
AT86200384T
Other languages
English (en)
Inventor
Haan Pieter De
Coenraad Ferdinand Lerk
Adelbert Jozef Martin Schoonen
Original Assignee
Univ Groningen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Groningen filed Critical Univ Groningen
Application granted granted Critical
Publication of ATE71521T1 publication Critical patent/ATE71521T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT86200384T 1985-03-13 1986-03-10 Einrichtungen fuer die kontrollierte abgabe von aktiven substanzen und verfahren zu ihrer herstellung. ATE71521T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8500724A NL8500724A (nl) 1985-03-13 1985-03-13 Inrichtingen voor geregelde afgifte van werkzame stoffen, alsmede werkwijze ter vervaardiging daarvan.
EP86200384A EP0196700B1 (de) 1985-03-13 1986-03-10 Einrichtungen für die kontrollierte Abgabe von aktiven Substanzen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE71521T1 true ATE71521T1 (de) 1992-02-15

Family

ID=19845674

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86200384T ATE71521T1 (de) 1985-03-13 1986-03-10 Einrichtungen fuer die kontrollierte abgabe von aktiven substanzen und verfahren zu ihrer herstellung.

Country Status (9)

Country Link
US (1) US4708874A (de)
EP (1) EP0196700B1 (de)
JP (1) JPH0776171B2 (de)
AT (1) ATE71521T1 (de)
AU (1) AU578577B2 (de)
CA (1) CA1265449C (de)
DE (1) DE3683385D1 (de)
DK (1) DK170244B1 (de)
NL (1) NL8500724A (de)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507832A (en) * 1982-09-23 1985-04-02 Technology Consulting Corporation Method and apparatus for the continuous treatment of yarn
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US4837032A (en) * 1986-02-04 1989-06-06 Farval Ag Theophylline sustained release tablet
US4861598A (en) * 1986-07-18 1989-08-29 Euroceltique, S.A. Controlled release bases for pharmaceuticals
US4970075A (en) * 1986-07-18 1990-11-13 Euroceltique, S.A. Controlled release bases for pharmaceuticals
NZ222698A (en) * 1987-01-08 1990-02-26 Squibb & Sons Inc Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base
US5015480A (en) * 1987-11-25 1991-05-14 Eli Lilly And Company Film coating formulations
JP2643222B2 (ja) * 1988-02-03 1997-08-20 エーザイ株式会社 多重層顆粒
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
US5196203A (en) * 1989-01-06 1993-03-23 F. H. Faulding & Co. Limited Theophylline dosage form
US5002774A (en) * 1989-06-08 1991-03-26 Erbamont, Inc. Sustained release pharmaceutical tablet
DE4127665A1 (de) * 1991-08-22 1993-02-25 Beiersdorf Ag Galenische matrix
DE4138513A1 (de) * 1991-11-23 1993-05-27 Basf Ag Feste pharmazeutische retardform
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5968551A (en) 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
IL119660A (en) * 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
KR950007873A (ko) * 1993-09-20 1995-04-15 후꾸하라 요시하루 생리 활성 물질 지속 방출형의 의약 제제
FR2718020B1 (fr) * 1994-04-01 1996-05-31 Biotec Centre Sa Composition galénique mucoadhésive hétérofonctionnelle.
AT403988B (de) * 1994-05-18 1998-07-27 Lannacher Heilmittel Festes orales retardpräparat
AU2540495A (en) * 1994-06-10 1996-01-05 Fernz Corporation Limited Biodegradable sustained release composition
US5744164A (en) * 1994-12-16 1998-04-28 Nestec S.A. Sustained release microparticulate caffeine formulation
DE29502547U1 (de) * 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
US5695781A (en) * 1995-03-01 1997-12-09 Hallmark Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers
US6083532A (en) 1995-03-01 2000-07-04 Duramed Pharmaceuticals, Inc. Sustained release formulation containing three different types of polymers and tablet formed therefrom
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
US6251430B1 (en) * 1998-02-04 2001-06-26 Guohua Zhang Water insoluble polymer based sustained release formulation
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
NZ511442A (en) 1998-11-02 2003-02-28 Elan Corp Plc Multiparticulate modified release composition for multiple dosing of ADD patients with methylphenidate HCl
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
US20090297597A1 (en) * 1998-11-02 2009-12-03 Gary Liversidge Modified Release Ticlopidine Compositions
US20090149479A1 (en) * 1998-11-02 2009-06-11 Elan Pharma International Limited Dosing regimen
US20070122481A1 (en) * 1998-11-02 2007-05-31 Elan Corporation Plc Modified Release Compositions Comprising a Fluorocytidine Derivative for the Treatment of Cancer
US6340478B1 (en) * 1999-06-07 2002-01-22 Bio Dar Ltd. Microencapsulated and controlled-release herbal formulations
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
IL131508A (en) 1999-08-19 2006-12-10 David Cohen Micronexulatory formulations and controlled dispersion of isoflavins from rich masses of sesame and other plants
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
ATE526950T1 (de) 1999-10-29 2011-10-15 Euro Celtique Sa Hydrocodon-formulierungen mit gesteuerter freisetzung
AT414205B (de) * 2000-06-20 2006-10-15 Vis Vitalis Lizenz & Handels Verfahren zur herstellung von ungesättigtem fettsäure-trockenkonzentrat
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
EP2263658A1 (de) 2000-10-30 2010-12-22 Euro-Celtique S.A. Hydrocodon-Formulierungen mit gesteuerter Freisetzung
UA81224C2 (uk) 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
KR20030060730A (ko) * 2002-01-09 2003-07-16 하나제약 주식회사 난용성 약물의 서방화 제제 조성물
HRP20020124A2 (en) * 2002-02-11 2003-10-31 Pliva D D Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
KR100540037B1 (ko) * 2003-06-27 2005-12-29 하나제약 주식회사 펠로디핀의 지속성 정제 및 그 제조방법
ZA200700952B (en) * 2004-08-06 2008-09-25 Nippon Soda Co Agricultural-chemical preparation having controlled releasability
US20060121112A1 (en) * 2004-12-08 2006-06-08 Elan Corporation, Plc Topiramate pharmaceutical composition
US20060159753A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Matrix type sustained-release preparation containing basic drug or salt thereof
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US20060160852A1 (en) * 2004-12-27 2006-07-20 Eisai Co. Ltd. Composition containing anti-dementia drug
NZ555693A (en) 2004-12-27 2010-10-29 Eisai R&D Man Co Ltd Matrix type sustained-release preparation containing donepezil
EA200701591A1 (ru) * 2005-01-26 2008-02-28 Элан Фарма Интернэшнл Лимитед Композиции с контролируемым высвобождением, содержащие антипсихотическое средство
US20070298098A1 (en) * 2005-02-16 2007-12-27 Elan Pharma International Limited Controlled Release Compositions Comprising Levetiracetam
BRPI0608917A2 (pt) * 2005-04-12 2017-07-11 Elan Pharma Int Ltd Composição de liberação controlada de antibiótico, e, método para o tratamento de infecção bacteriana
US20100136106A1 (en) * 2005-06-08 2010-06-03 Gary Liversidge Modified Release Famciclovir Compositions
US20070224233A1 (en) * 2005-08-05 2007-09-27 Nippon Soda Co., Ltd Controlled-Release Agricultural Chemical Formulation
PL1982590T3 (pl) * 2006-02-06 2017-11-30 Nippon Soda Co., Ltd. Zawierające pestycyd kompozycje żywiczne o kontrolowanym rozpuszczaniu, sposób ich wytwarzania i preparaty pestycydowe
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
US20080075771A1 (en) * 2006-07-21 2008-03-27 Vaughn Jason M Hydrophilic opioid abuse deterrent delivery system using opioid antagonists
US8992898B2 (en) 2010-04-17 2015-03-31 Shannon Elizabeth Klingman Antiperspirants and deodorants
US20140179615A1 (en) * 2012-07-12 2014-06-26 Hainan Weikang Pharmaceutical (Qianshan) Co., Ltd. Glutathione and Acetaminophen Composition and Preparation Method Thereof
CN113842362A (zh) 2012-11-14 2021-12-28 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10645931B2 (en) * 2016-12-15 2020-05-12 Wellmark International Extended release formulation
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2793979A (en) * 1953-03-30 1957-05-28 Smith Kline French Lab Method of making a sustained release pharmaceutical tablet and product of the method
US2996431A (en) * 1953-12-16 1961-08-15 Barry Richard Henry Friable tablet and process for manufacturing same
US3166476A (en) * 1961-09-01 1965-01-19 Lowey Hans Powder based tablets
BE640616A (de) * 1962-12-19
IE32806B1 (en) * 1968-05-21 1973-12-12 American Home Prod Sustained release drug composition
US3634584A (en) * 1969-02-13 1972-01-11 American Home Prod Sustained action dosage form
GB1405088A (en) * 1971-06-03 1975-09-03 Mundipharma Ag Slow release formulation
US3965256A (en) * 1972-05-16 1976-06-22 Synergistics Slow release pharmaceutical compositions
DE2426811A1 (de) * 1974-06-04 1976-01-08 Klinge Co Chem Pharm Fab Verfahren zur herstellung von retard-tabletten
US4139589A (en) * 1975-02-26 1979-02-13 Monique Beringer Process for the manufacture of a multi-zone tablet and tablet manufactured by this process
GB1576376A (en) * 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
FR2403080A1 (fr) * 1977-09-15 1979-04-13 Heyden Chem Fab Preparation de nitrofurantoine a effet retard pour administration orale et son procede de fabrication
US4210139A (en) * 1979-01-17 1980-07-01 Alza Corporation Osmotic device with compartment for governing concentration of agent dispensed from device
JPS55153715A (en) * 1979-05-18 1980-11-29 Nikken Kagaku Kk Prolonged granule of theophylline
JPS5661311A (en) * 1979-10-25 1981-05-26 Fujisawa Pharmaceut Co Ltd Thial amide or prolonged pharmaceutical preparation comprising its salt
JPS56122311A (en) * 1980-02-29 1981-09-25 Eisai Co Ltd Lasting theophylline pharmaceutical composition
JPS5826816A (ja) * 1981-08-11 1983-02-17 Teisan Seiyaku Kk 球形顆粒からなる持続性複合顆粒剤
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
JPS5883613A (ja) * 1981-11-10 1983-05-19 Toa Eiyou Kagaku Kogyo Kk 硝酸イソソルビト−ル製剤
DE3218150C2 (de) * 1982-05-14 1986-09-25 Akzo Gmbh, 5600 Wuppertal Wirkstoff enthaltender Körper für die Langzeitabgabe sowie Verfahren zu dessen Herstellung
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
DK152744C (da) * 1982-08-13 1988-10-31 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation

Also Published As

Publication number Publication date
JPH0776171B2 (ja) 1995-08-16
EP0196700B1 (de) 1992-01-15
NL8500724A (nl) 1986-10-01
AU578577B2 (en) 1988-10-27
JPS61251617A (ja) 1986-11-08
AU5465186A (en) 1986-09-18
CA1265449A (en) 1990-02-06
US4708874A (en) 1987-11-24
DK114886A (da) 1986-09-14
CA1265449C (en) 1990-02-06
DE3683385D1 (de) 1992-02-27
DK170244B1 (da) 1995-07-17
DK114886D0 (da) 1986-03-12
EP0196700A1 (de) 1986-10-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee