[go: up one dir, main page]

ATE67783T1 - Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE67783T1
ATE67783T1 AT87111281T AT87111281T ATE67783T1 AT E67783 T1 ATE67783 T1 AT E67783T1 AT 87111281 T AT87111281 T AT 87111281T AT 87111281 T AT87111281 T AT 87111281T AT E67783 T1 ATE67783 T1 AT E67783T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
compositions containing
immune interferon
homogeneous recombinant
recombinant immune
Prior art date
Application number
AT87111281T
Other languages
English (en)
Inventor
Heinz Dr Doebeli
Reiner Dr Gentz
Erich Dr Hochuli
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE67783T1 publication Critical patent/ATE67783T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT87111281T 1986-08-13 1987-08-04 Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen. ATE67783T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868619725A GB8619725D0 (en) 1986-08-13 1986-08-13 Homogenous interferon fragments
EP87111281A EP0256424B1 (de) 1986-08-13 1987-08-04 Homogene rekombinante Immun-Interferon-Fragmente und diese enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE67783T1 true ATE67783T1 (de) 1991-10-15

Family

ID=10602667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87111281T ATE67783T1 (de) 1986-08-13 1987-08-04 Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen.

Country Status (21)

Country Link
EP (1) EP0256424B1 (de)
JP (1) JPS6349098A (de)
KR (1) KR880002996A (de)
AR (1) AR244808A1 (de)
AT (1) ATE67783T1 (de)
AU (1) AU607930B2 (de)
DE (1) DE3773295D1 (de)
DK (1) DK377787A (de)
ES (1) ES2051714T3 (de)
FI (1) FI873512A (de)
GB (1) GB8619725D0 (de)
GR (1) GR3003417T3 (de)
HU (1) HU202920B (de)
IE (1) IE60670B1 (de)
IL (1) IL83474A0 (de)
MC (1) MC1847A1 (de)
NO (1) NO174631C (de)
NZ (1) NZ221374A (de)
PH (1) PH27432A (de)
PT (1) PT85538B (de)
ZA (1) ZA875819B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2969461B2 (ja) * 1988-07-23 1999-11-02 株式会社林原生物化学研究所 ヒトγ−インターフェロンとその製造方法並びに用途
DE3730331A1 (de) * 1987-09-10 1989-03-30 Basf Ag Neue polypeptide, verfahren zur herstellung, die vektoren dafuer und arzneimittel daraus
AU8640091A (en) * 1990-08-31 1992-03-30 Schering Corporation Human interferon-gamma4-134, functional equivalents thereof and methods of using and compositions employing these materials
DE4036856C1 (de) * 1990-11-19 1992-05-27 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
EP1231943A1 (de) 1999-11-12 2002-08-21 Maxygen Holdings Ltd Interferon-gamma konjugate
CN1309423C (zh) 1999-11-12 2007-04-11 马克西根控股公司 干扰素γ偶联物
US7959910B2 (en) 2000-07-31 2011-06-14 Biolex Therapeutics, Inc. C-terminally truncated interferon alpha variants
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
US7524931B2 (en) 2002-07-03 2009-04-28 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants
US20060024272A1 (en) * 2004-07-29 2006-02-02 Large Scale Biology Corporation C-terminally truncated interferon

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
JPS60172999A (ja) * 1983-12-20 1985-09-06 Suntory Ltd 新規な塩基性ポリペプチドおよびその製造法
DK168016B1 (da) * 1983-12-26 1994-01-17 Kyowa Hakko Kogyo Kk Derivat af humant interferon-gamma-polypeptid
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
WO1985005618A1 (en) * 1984-06-06 1985-12-19 Takeda Chemical Industries, Ltd. Process for preparing interferon derivative
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof
JPS6124599A (ja) * 1984-07-11 1986-02-03 Kyowa Hakko Kogyo Co Ltd 新規ヒトインタ−フエロン−ｒポリペプチド誘導体
JPS6163696A (ja) * 1984-09-05 1986-04-01 Asahi Chem Ind Co Ltd 新しいペプチド
JPS61108397A (ja) * 1984-10-31 1986-05-27 Green Cross Corp:The インタ−フエロン−γ蛋白質の製造法
JPS62289600A (ja) * 1986-02-18 1987-12-16 Kanegafuchi Chem Ind Co Ltd インタ−フエロン−γ及びその製造方法

Also Published As

Publication number Publication date
GR3003417T3 (en) 1993-02-17
EP0256424B1 (de) 1991-09-25
FI873512A0 (fi) 1987-08-13
HU202920B (en) 1991-04-29
KR880002996A (ko) 1988-05-13
IE872160L (en) 1988-02-13
HUT47148A (en) 1989-01-30
IE60670B1 (en) 1994-08-10
MC1847A1 (fr) 1988-09-30
DK377787D0 (da) 1987-07-20
AU7668687A (en) 1988-05-19
NO873389D0 (no) 1987-08-12
PT85538A (en) 1987-09-01
JPS6349098A (ja) 1988-03-01
AR244808A1 (es) 1993-11-30
DK377787A (da) 1988-02-14
NO873389L (no) 1988-02-15
ES2051714T3 (es) 1994-07-01
GB8619725D0 (en) 1986-09-24
AU607930B2 (en) 1991-03-21
IL83474A0 (en) 1988-01-31
PT85538B (pt) 1990-06-29
EP0256424A1 (de) 1988-02-24
DE3773295D1 (de) 1991-10-31
NO174631C (no) 1994-06-08
PH27432A (en) 1993-06-21
NZ221374A (en) 1990-07-26
NO174631B (no) 1994-02-28
FI873512A (fi) 1988-02-14
ZA875819B (en) 1988-02-15

Similar Documents

Publication Publication Date Title
IL87621A0 (en) Conjugates of cytokines with immunoglobulins,their preparation and pharmaceutical compositions containing them
IT1231434B (it) Composizione farmaceutica endovenosa e procedimento per la sua preparazione.
NZ222980A (en) 3-aryloxy-3-substituted propanamines and pharmaceutical compositions
IL100062A0 (en) Tnf muteins,their preparation and pharmaceutical compositions containing them
NZ223096A (en) Peptidylaminodiols and pharmaceutical compositions
DE3486441D1 (de) 3-Hydroxypyrid-4-one und pharmazeutische Zusammensetzungen
NZ220365A (en) Antiviral peptides and pharmaceutical compositions
DE3875108D1 (de) Physiologisch aktives polypeptid und pharmazeutische komposition.
NZ220441A (en) Unca-hydrazide-immunoglobulin (glyoprotein) conjugates and pharmaceutical composition
IL93490A0 (en) Pharmaceutical compositions comprising ranitidine
ATE67783T1 (de) Homogene rekombinante immun-interferon-fragmente und diese enthaltende pharmazeutische zusammensetzungen.
IL71951A0 (en) Polypeptides having interferon activity,their preparation and pharmaceutical compositions containing them
DE3579730D1 (de) Eisen-3-hydroxypyron- oder 3-hydroxypyridon-komplexe und diese enthaltende pharmazeutische zusammensetzungen.
IT1239542B (it) Composizione farmaceutica comprendente piroxicam e procedimento per lasua preparazione
IL84484A0 (en) T-cell suppressor protein in pure form,its preparation by recombinant methods and pharmaceutical compositions containing it
DE3583765D1 (de) Hydantoinderivate und diese enthaltende pharmazeutische zusammensetzungen.
IL89778A (en) Unsaturated n-benzopyranyllactams, their preparation and pharmaceutical compositions containing them
IL67978A0 (en) Human immune interferon,its preparation and purification and pharmaceutical compositions containing it
IL88404A0 (en) Neutrophil activating factor,its preparation and pharmaceutical compositions containing it
FR2630430B1 (fr) Nouvelles compositions vitreuses luminescentes, leur preparation et leur application
IL82143A0 (en) Pharmaceutical compositions containing interleukin-2 and/or interferon-beta and tumor necrosis factor
ATE189262T1 (de) Interferon-alpha/beta bindendes protein, seine herstellung und seine enthaltende pharmazeutische zusammensetzungen
EE9400337A (et) Alfainterferooni sisaldavad farmatseutilised kompositsioonid ja nende kasutusvõimalused
IL88934A0 (en) Recombinant human interleukin-1alpha polypeptides,their preparation and pharmaceutical compositions containing them
NZ220770A (en) Benzimidazoles and pharmaceutical compositions

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee