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ATE63541T1 - N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel. - Google Patents

N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel.

Info

Publication number
ATE63541T1
ATE63541T1 AT88302270T AT88302270T ATE63541T1 AT E63541 T1 ATE63541 T1 AT E63541T1 AT 88302270 T AT88302270 T AT 88302270T AT 88302270 T AT88302270 T AT 88302270T AT E63541 T1 ATE63541 T1 AT E63541T1
Authority
AT
Austria
Prior art keywords
phenylethylaminoalkyl
antiarhythmic
benzamides
agents
alkyl
Prior art date
Application number
AT88302270T
Other languages
English (en)
Inventor
Peter Edward Dr Cross
John Edmund Dr Arrowsmith
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Application granted granted Critical
Publication of ATE63541T1 publication Critical patent/ATE63541T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT88302270T 1987-03-20 1988-03-16 N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel. ATE63541T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878706662A GB8706662D0 (en) 1987-03-20 1987-03-20 Anti-arrhythmia agents
EP88302270A EP0285284B1 (de) 1987-03-20 1988-03-16 N-phényléthylaminoalkyl-Benzamide als antiarrhythmische Mittel

Publications (1)

Publication Number Publication Date
ATE63541T1 true ATE63541T1 (de) 1991-06-15

Family

ID=10614327

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88302270T ATE63541T1 (de) 1987-03-20 1988-03-16 N-phenylethylaminoalkyl-benzamide als antiarrhythmische mittel.

Country Status (9)

Country Link
EP (1) EP0285284B1 (de)
JP (1) JPS63255258A (de)
AT (1) ATE63541T1 (de)
DE (1) DE3862791D1 (de)
DK (1) DK148288A (de)
ES (1) ES2035915T3 (de)
GB (1) GB8706662D0 (de)
GR (1) GR3001955T3 (de)
PT (1) PT87005B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
US5032604A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
US5112824A (en) * 1989-12-08 1992-05-12 Merck & Co., Inc. Benzofuran compounds as class III antiarrhythmic agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US5215989A (en) * 1989-12-08 1993-06-01 Merck & Co., Inc. Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4544654A (en) * 1984-03-20 1985-10-01 Schering A.G. Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof
DE3566886D1 (en) * 1984-05-04 1989-01-26 Upjohn Co N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use
CA1241967A (en) * 1984-05-11 1988-09-13 George C. Buzby Jr. Sulfonamides useful as anti-arrhythmic agents
US4569801A (en) * 1984-10-15 1986-02-11 Eli Lilly And Company Alkylsulfonamidophenylalkylamines

Also Published As

Publication number Publication date
GR3001955T3 (en) 1992-11-23
DE3862791D1 (de) 1991-06-20
EP0285284A2 (de) 1988-10-05
DK148288A (da) 1988-12-30
GB8706662D0 (en) 1987-04-23
PT87005B (pt) 1992-06-30
EP0285284B1 (de) 1991-05-15
JPS63255258A (ja) 1988-10-21
EP0285284A3 (en) 1989-03-29
ES2035915T3 (es) 1993-05-01
DK148288D0 (da) 1988-03-18
PT87005A (pt) 1988-04-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee