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ATE551433T1 - Verfahren und produkte zum erfassen von nukleinsäurezielen - Google Patents

Verfahren und produkte zum erfassen von nukleinsäurezielen

Info

Publication number
ATE551433T1
ATE551433T1 AT06752336T AT06752336T ATE551433T1 AT E551433 T1 ATE551433 T1 AT E551433T1 AT 06752336 T AT06752336 T AT 06752336T AT 06752336 T AT06752336 T AT 06752336T AT E551433 T1 ATE551433 T1 AT E551433T1
Authority
AT
Austria
Prior art keywords
nucleic acid
target nucleic
products
detecting nucleic
acid targets
Prior art date
Application number
AT06752336T
Other languages
English (en)
Inventor
Reinhold B Pollner
Michael M Becker
Mehrdad R Majlessi
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of ATE551433T1 publication Critical patent/ATE551433T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT06752336T 2005-05-06 2006-05-05 Verfahren und produkte zum erfassen von nukleinsäurezielen ATE551433T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67850705P 2005-05-06 2005-05-06
PCT/US2006/017472 WO2006121888A2 (en) 2005-05-06 2006-05-05 Methods of nucleic acid target capture

Publications (1)

Publication Number Publication Date
ATE551433T1 true ATE551433T1 (de) 2012-04-15

Family

ID=36954672

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06752336T ATE551433T1 (de) 2005-05-06 2006-05-05 Verfahren und produkte zum erfassen von nukleinsäurezielen

Country Status (8)

Country Link
US (2) US7993853B2 (de)
EP (1) EP1877581B1 (de)
JP (1) JP5187847B2 (de)
AT (1) ATE551433T1 (de)
AU (1) AU2006244394B2 (de)
CA (1) CA2584230C (de)
ES (1) ES2381279T3 (de)
WO (1) WO2006121888A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008020813A1 (en) * 2006-08-16 2008-02-21 Agency For Science, Technology And Research Method of electrically detecting a biological analyte molecule
EP2479287B1 (de) 2008-05-13 2014-07-23 Gen-Probe Incorporated Inaktivierbare Target-Capture-Oligomere zur Verwendung bei der selektiven Hybridisierung und Fangen von Zielnukleinsäuresequenzen
JP5592357B2 (ja) * 2008-05-27 2014-09-17 ダコ・デンマーク・エー/エス 新規なハイブリダイゼーションバッファーを用いた染色体異常の検出のための組成物及び方法
CA2723917A1 (en) 2008-05-30 2009-12-30 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of salmonella
EP2358898B1 (de) * 2008-11-17 2016-08-31 Headway Technologies, Inc. Verfahren und zusammensetzungen bei dem nachweis von zielmolekülen auf partikelbasis unter verwendung von kovalente bindungen ausbildenden reaktiven paaren
US9150910B2 (en) * 2008-11-17 2015-10-06 Headway Technologies, Inc. Methods and compositions in particle-based detection of target molecules using linking molecules
US9388456B2 (en) 2009-02-26 2016-07-12 Dako Denmark A/S Compositions and methods for performing a stringent wash step in hybridization applications
GB0912909D0 (en) * 2009-07-23 2009-08-26 Olink Genomics Ab Probes for specific analysis of nucleic acids
EP3301195B1 (de) 2010-07-12 2022-11-02 Gen-Probe Incorporated Zusammensetzungen und assays zur detektion der 2009 h1n1-influenza-a-virus-nukleinsäure in schweinen
JP5838550B2 (ja) * 2010-12-22 2016-01-06 東ソー株式会社 クラミジア・トラコマチスrnaの検出方法及び検出試薬
EP2675917B1 (de) 2011-02-16 2017-09-13 Headway Technologies, Inc. Verfahren und zusammensetzungen zur verankerung eines erkennbaren etiketts an einem lokalisierten ziel
US10662465B2 (en) 2011-09-30 2020-05-26 Agilent Technologies, Inc. Hybridization compositions and methods using formamide
EP2768974B1 (de) 2011-10-21 2017-07-19 Dako Denmark A/S Hybridisierungszusammensetzungen und -verfahren
WO2014164730A2 (en) 2013-03-12 2014-10-09 The Board Of Trustees Of The Leland Stanford Junior University Modulation of cellular dna repair activity to intercept malignancy
CN106133145B (zh) 2014-02-28 2020-04-14 简·探针公司 从含有甲醛的液基细胞学防腐剂中的样本分离核酸的方法
DE102015203606C5 (de) 2014-02-28 2023-12-21 Gen-Probe Incorporated Verfahren zur Isolierung von Nukleinsäure von zytologischen Proben in flüssigen Konservierungsmitteln, die Formaldehyd enthalten
CN108350448A (zh) * 2015-09-10 2018-07-31 株式会社钟化 从含有核酸的样品中分离核酸的方法及用于该方法的装置
WO2021127406A1 (en) * 2019-12-19 2021-06-24 The Regents Of The University Of California Methods of producing target capture nucleic acids

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
US4358535A (en) 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
FI63596C (fi) 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4556643A (en) 1982-07-26 1985-12-03 Agracetus Assay method and probe for polynucleotide sequences
US4672040A (en) 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4777129A (en) 1983-12-12 1988-10-11 Molecular Diagnostics, Inc. Nucleic acid probe detectable by specific nucleic acid binding protein
FI71768C (fi) 1984-02-17 1987-02-09 Orion Yhtymae Oy Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
GB8405437D0 (en) 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
CA1260372A (en) 1984-04-27 1989-09-26 Elazar Rabbani Hybridization method for the detection of genetic materials
US5288609A (en) 1984-04-27 1994-02-22 Enzo Diagnostics, Inc. Capture sandwich hybridization method and composition
US4749647A (en) 1984-06-22 1988-06-07 Genetic Systems Corporation Polymerization-induced separation assay using recognition pairs
US4755458A (en) 1984-08-30 1988-07-05 Enzo Biochem, Inc. Composition and method for the detection of the presence of a polynucleotide sequence of interest
US4563417A (en) 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes
US5273882A (en) 1985-06-13 1993-12-28 Amgen Method and kit for performing nucleic acid hybridization assays
US4751177A (en) 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
US4797355A (en) 1985-06-13 1989-01-10 Amgen Inc. Methods for attaching polynucleotides to supports
US4868105A (en) 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4818680A (en) 1985-12-18 1989-04-04 Mary Collins Method and kit involving displacement and rehybridization of labeled polynucleotide
US4925785A (en) 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
US5750338A (en) 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US5541308A (en) 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
AU622104B2 (en) 1987-03-11 1992-04-02 Sangtec Molecular Diagnostics Ab Method of assaying of nucleic acids, a reagent combination and kit therefore
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5124246A (en) 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5030557A (en) 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
US4895650A (en) 1988-02-25 1990-01-23 Gen-Probe Incorporated Magnetic separation rack for diagnostic assays
US5656207A (en) 1989-06-24 1997-08-12 Gen Probe Incorporated Detecting or quantifying multiple analytes using labelling techniques
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5200314A (en) 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
WO1992015708A1 (en) * 1991-02-27 1992-09-17 Amoco Corporation Methods for improving the sensitivity of hybridization assays
JP3739785B2 (ja) 1991-11-26 2006-01-25 アイシス ファーマシューティカルズ,インコーポレイティド 修飾されたピリミジンを含有するオリゴマーを使用する増強された三重らせんおよび二重らせんの成形
AU681082B2 (en) 1992-05-06 1997-08-21 Gen-Probe Incorporated Nucleic acid sequence amplification method, composition and kit
US5681697A (en) 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
DE69535240T2 (de) 1994-10-28 2007-06-06 Gen-Probe Inc., San Diego Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen
US6270962B1 (en) 1995-01-30 2001-08-07 The Regents Of The University Of California Methods for the elimination of DNA sequencing artifacts
US5731153A (en) 1996-08-26 1998-03-24 The Regents Of The University Of California Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions
US5731148A (en) 1995-06-07 1998-03-24 Gen-Probe Incorporated Adduct protection assay
AU723889B2 (en) 1995-10-18 2000-09-07 Qiagen Genomics, Inc. Methods for preparing solid supports for hybridization and reducing non-specific background
EP0808906B1 (de) 1996-05-23 2000-09-20 QIAGEN GmbH Verwendung eines Osmolyten zur Verringerung oder Aufhebung von nichtkovalenten Bindungen biologischer Moleküle an inerten Oberflächen
WO1998002582A2 (en) 1996-07-16 1998-01-22 Gen-Probe Incorporated Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific t¿m?
US6013488A (en) 1996-07-25 2000-01-11 The Institute Of Physical And Chemical Research Method for reverse transcription
US6060246A (en) * 1996-11-15 2000-05-09 Avi Biopharma, Inc. Reagent and method for isolation and detection of selected nucleic acid sequences
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
WO1998050583A1 (en) * 1997-05-02 1998-11-12 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US20020197614A1 (en) * 1997-05-16 2002-12-26 Mosaic Technologies, Inc. Electrophoretic analysis of target molecules using adapter molecules
US6268133B1 (en) * 1997-06-25 2001-07-31 Invitrogen Corporation Method for isolating and recovering target DNA or RNA molecules having a desired nucleotide sequence
US6221589B1 (en) * 1997-07-17 2001-04-24 Tm Technologies, Inc. Methods and compositions for modulating melting temperatures of nucleic acids
IL123256A0 (en) 1998-02-10 1998-09-24 Yeda Res & Dev Methods for dna amplification and sequencing
WO2000026412A1 (en) * 1998-11-02 2000-05-11 Kenneth Loren Beattie Nucleic acid analysis using sequence-targeted tandem hybridization
US6673940B1 (en) 1999-01-08 2004-01-06 California Institute Of Technology Compositions and methods relating to cyclic compounds that undergo nucleotide base pair-specific interactions with double-stranded nucleic acids
JP2003508015A (ja) * 1999-04-02 2003-03-04 モザイク テクノロジーズ インコーポレーテッド アダプター分子を用いる標的分子の電気泳動分析
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
US20040014644A1 (en) * 2000-03-14 2004-01-22 Vladimir Efimov Oligonucleotide analogues and methods of use for modulating gene expression
EP1377679B1 (de) * 2000-12-14 2009-10-28 Gen-Probe Incorporated Verfahren und kits zur verbesserung der hybridisierungsraten von polynukleotiden
WO2003040689A2 (en) * 2001-11-02 2003-05-15 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of mycoplasma pneumoniae and/or mycoplasma genitalium in a test sample
ES2370169T3 (es) 2002-06-14 2011-12-13 Gen-Probe Incorporated Composiciones y métodos para detectar el virus de la hepatitis b.
US8084032B2 (en) * 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
WO2006007567A2 (en) * 2004-07-01 2006-01-19 Gen-Probe Incorporated Methods and compositions to detect nucleic acids in a biological sample
CA2629589C (en) * 2007-04-20 2016-03-29 F.Hoffmann-La Roche Ag Isolation and purification of nucleic acid molecules with a solid phase
CA2629586C (en) 2007-04-20 2016-05-24 F.Hoffmann-La Roche Ag Adsorption of nucleic acids to solid phases under low-salt conditions

Also Published As

Publication number Publication date
CA2584230C (en) 2012-11-27
AU2006244394A1 (en) 2006-11-16
WO2006121888A3 (en) 2007-02-15
CA2584230A1 (en) 2006-11-16
US7993853B2 (en) 2011-08-09
EP1877581A2 (de) 2008-01-16
JP5187847B2 (ja) 2013-04-24
WO2006121888A2 (en) 2006-11-16
EP1877581B1 (de) 2012-03-28
AU2006244394B2 (en) 2010-10-21
US20110250698A1 (en) 2011-10-13
US20060252085A1 (en) 2006-11-09
JP2008539736A (ja) 2008-11-20
ES2381279T3 (es) 2012-05-24

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