US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
SE378110B
(de)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
SE378109B
(de)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
DK149080C
(da)
|
1980-06-06 |
1986-07-28 |
Sankyo Co |
Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
3−ヒドロキシ−ml−236b誘導体の製造法
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
EP0360390A1
(de)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactamderivate
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
FI97540C
(fi)
|
1989-11-06 |
1997-01-10 |
Sanofi Sa |
Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
WO1991009844A1
(en)
|
1990-01-04 |
1991-07-11 |
Pfizer Inc. |
Substance p antagonists
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
WO1991012266A1
(en)
|
1990-02-15 |
1991-08-22 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compound
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
ES2063507T3
(es)
|
1990-06-01 |
1995-01-01 |
Pfizer |
3-amino-2-aril-quinuclidinas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
|
EP0540526B1
(de)
|
1990-07-23 |
1994-12-28 |
Pfizer Inc. |
Chinuclidinderivate
|
WO1994004494A1
(en)
|
1992-08-13 |
1994-03-03 |
Warner-Lambert Company |
Tachykinin antagonists
|
JPH0772175B2
(ja)
|
1990-09-28 |
1995-08-02 |
フアイザー・インコーポレイテツド |
窒素含有非芳香族複素環の縮合環類似体
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
DE69114117T2
(de)
|
1990-12-21 |
1996-03-21 |
Fujisawa Pharmaceutical Co |
Neue Verwendung von Peptidderivat.
|
AU652407B2
(en)
|
1991-01-10 |
1994-08-25 |
Pfizer Inc. |
N-alkyl quinuclidinium salts as substance P antagonists
|
US5242930A
(en)
|
1991-02-11 |
1993-09-07 |
Merck Sharp & Dohme Ltd. |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
CA2105302C
(en)
|
1991-03-01 |
1996-11-12 |
Pfizer Limited |
1-azabicyclo¬3.2.2.|nonan-3-amine derivatives
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
CZ289960B6
(cs)
|
1991-03-26 |
2002-05-15 |
Pfizer Inc. |
Způsob přípravy substituovaných piperidinů
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
EP0585328B1
(de)
|
1991-05-22 |
2002-01-09 |
Pfizer Inc. |
Substituierte 3-aminochinuclidine
|
US5292726A
(en)
|
1991-05-22 |
1994-03-08 |
Merck & Co., Inc. |
N,N-diacylpiperazines
|
DE122006000066I2
(de)
|
1991-05-31 |
2007-12-06 |
Pfizer |
Chinuclidinderivate
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
JPH07110850B2
(ja)
|
1991-06-20 |
1995-11-29 |
フアイザー・インコーポレイテツド |
窒素含有複素環化合物のフルオロアルコキシベンジルアミノ誘導体
|
TW202432B
(de)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
EP0593559A1
(de)
|
1991-07-05 |
1994-04-27 |
MERCK SHARP & DOHME LTD. |
Aromatische verbindungen, diese enthaltende arzneimittel und ihre therapeutische verwendung
|
EP0522808A3
(de)
|
1991-07-05 |
1993-01-27 |
MERCK SHARP & DOHME LTD. |
Aromatische Verbindungen, diese enthaltende pharmazeutische Zusammensetzungen und ihre therapeutische Anwendung
|
EP0536817A1
(de)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclische Verbindungen als Tachykinin-Antagonisten
|
WO1993001159A1
(en)
|
1991-07-10 |
1993-01-21 |
Merck Sharp & Dohme Limited |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
US5610183A
(en)
|
1991-07-10 |
1997-03-11 |
Merck, Sharp & Dohme Ltd. |
Phenylglycine derivatives pharmaceutical compositions containing them and their use in therapy
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
EP0528495A1
(de)
|
1991-08-20 |
1993-02-24 |
Merck Sharp & Dohme Ltd. |
Azacyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
|
DK0533280T4
(da)
|
1991-09-20 |
2005-02-28 |
Glaxo Group Ltd |
Ny medicinsk anvendelse af tachykininantagonister
|
DK0607164T3
(da)
|
1991-09-26 |
2002-06-17 |
Pfizer |
Kondenserede tricykliske nitrogenholdige heterocykliske forbindelser som substans P-receptorantagonister
|
JP2553020B2
(ja)
|
1991-11-07 |
1996-11-13 |
吉富製薬株式会社 |
キヌクリジン化合物およびその医薬用途
|
DK0613458T3
(da)
|
1991-11-12 |
1998-02-09 |
Pfizer |
Acykliske ethylendiaminderivater som substans P receptorantagonister
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
HU217629B
(hu)
|
1991-12-12 |
2000-03-28 |
Novartis Ag. |
Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
AU675786B2
(en)
|
1992-04-15 |
1997-02-20 |
Merck Sharp & Dohme Limited |
Azacyclic compounds
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
ES2164657T3
(es)
|
1992-05-18 |
2002-03-01 |
Pfizer |
Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
IL106142A
(en)
|
1992-06-29 |
1997-03-18 |
Merck & Co Inc |
Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
US5612336A
(en)
|
1992-07-13 |
1997-03-18 |
Merck, Sharp & Dohme Ltd. |
Heterocyclic amide derivatives as tachykinin antagonists
|
JPH07509133A
(ja)
|
1992-07-17 |
1995-10-12 |
リボザイム・ファーマシューティカルズ・インコーポレイテッド |
動物疾患の処置のための方法および剤
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
EP0652866B1
(de)
|
1992-07-28 |
1998-11-25 |
MERCK SHARP & DOHME LTD. |
Azazyklische verbindungen
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
WO1994003429A1
(en)
|
1992-07-31 |
1994-02-17 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
AU4396193A
(en)
|
1992-08-04 |
1994-03-03 |
Pfizer Inc. |
3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
EP1114823A3
(de)
|
1992-08-19 |
2001-07-18 |
Pfizer Inc. |
Substituierte Benzylamin-Stickstoff enthaltende nichtaromatische Heterocyclen
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
US5482967A
(en)
|
1992-09-04 |
1996-01-09 |
Takeda Chemical Industries, Ltd. |
Condensed heterocyclic compounds, their production and use
|
WO1994005625A1
(en)
|
1992-09-10 |
1994-03-17 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO1994010165A1
(en)
|
1992-10-28 |
1994-05-11 |
Merck Sharp & Dohme Limited |
4-arylmethyloxymethyl piperidines as tachykinin antagonists
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
AU5342894A
(en)
|
1992-10-30 |
1994-05-24 |
Merck Sharp & Dohme Limited |
Tachykinin antagonists
|
NZ254604A
(en)
|
1992-11-12 |
1997-06-24 |
Pfizer |
Quinuclidine derivative and pharmaceutical compositions thereof
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
DE69328975T2
(de)
|
1992-12-10 |
2000-11-09 |
Pfizer Inc., New York |
Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
EP0673367A1
(de)
|
1992-12-14 |
1995-09-27 |
MERCK SHARP & DOHME LTD. |
4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenyl-piperidine als tachykinin rezeptor antagonisten
|
EP0604181A1
(de)
|
1992-12-21 |
1994-06-29 |
Eli Lilly And Company |
Antitumorpräparate und Behandlungsmethoden
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
ES2111288T3
(es)
|
1993-01-15 |
1998-03-01 |
Searle & Co |
Nuevos 3,4-diaril tiofenos y analogos de los mismos utiles como agentes antiinflamatorios.
|
US5466689A
(en)
|
1993-02-08 |
1995-11-14 |
Takeda Chemical Industries, Ltd. |
Morpholine derivatives and their use
|
AU679207B2
(en)
|
1993-02-18 |
1997-06-26 |
Merck Sharp & Dohme Limited |
Azacyclic compounds, compositions containing them and their use as tachykinin antagonists
|
US5674889A
(en)
|
1993-02-22 |
1997-10-07 |
Merck, Sharp & Dohme, Ltd. |
Aromatic compounds, compositions containing them and their use in therapy
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
DK0687268T3
(da)
|
1993-03-04 |
1998-10-12 |
Pfizer |
Spiroazacykliske derivater som substans P-antagonister
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
ATE158580T1
(de)
|
1993-05-06 |
1997-10-15 |
Merrell Pharma Inc |
Substituierte pyrrolidin-3-alkyl-piperidine verwendbar als tachykinin-antagonisten
|
CA2160786A1
(en)
|
1993-05-14 |
1994-11-24 |
James C. Marsters, Jr. |
Ras farnesyl transferase inhibitors
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
AU680020B2
(en)
|
1993-06-07 |
1997-07-17 |
Merck & Co., Inc. |
Spiro-substituted azacycles as neurokinin antagonists
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
EP0634402A1
(de)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinon-Derivate, ihre Herstellung und Verwendung
|
CA2167198C
(en)
|
1993-07-15 |
1999-03-16 |
Kunio Satake |
Benzylaminoquinuclidines
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
EP0719253B1
(de)
|
1993-09-17 |
2004-04-28 |
Pfizer Inc. |
3-amino-5-carboxy-substituierte piperidine und 3-amino-4-carboxy-substituierte pyrrolidine als tachykinin-antagonisten
|
AU7082194A
(en)
|
1993-09-17 |
1995-04-03 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
|
US5728830A
(en)
|
1993-09-22 |
1998-03-17 |
Kyowa Hakko Kogyo Co., Ltd. |
Farnesyltransferase inhibitor
|
IL111002A
(en)
|
1993-09-22 |
1998-09-24 |
Glaxo Group Ltd |
History of piperidine, their preparation and the pharmaceutical preparations containing them
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
NZ275646A
(en)
|
1993-10-15 |
1998-02-26 |
Schering Corp |
Tricyclic sulphonamide derivatives and medicaments
|
NZ274749A
(en)
|
1993-10-15 |
1998-05-27 |
Schering Corp |
Tricyclic carbamate derivatives useful for inhibition of g-protein function and for treating proliferative diseases, medicaments
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
WO1995011917A1
(en)
|
1993-10-25 |
1995-05-04 |
Parke, Davis & Company |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
AU7947594A
(en)
|
1993-10-27 |
1995-05-22 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
DE69417012T2
(de)
|
1993-11-04 |
1999-10-07 |
Abbott Laboratories, Abbott Park |
Cyclobutan-derivate als inhibitoren der squalen-synthetase und der protein-farnesyltransferase
|
CA2170766A1
(en)
|
1993-11-05 |
1995-05-11 |
Gary Louis Bolton |
Substituted di- and tripeptide inhibitors of protein:farnesyl transferase
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
WO1995017382A1
(en)
|
1993-12-21 |
1995-06-29 |
Eli Lilly And Company |
Non-peptide tachykinin receptor antagonists
|
US5612337A
(en)
|
1993-12-29 |
1997-03-18 |
Merck Sharp & Dohme Limited |
Substituted morpholine derivatives and their use as therapeutic agents
|
RU2124014C1
(ru)
|
1993-12-29 |
1998-12-27 |
Пфайзер Инк. |
Диазабициклические соединения и содержащая их фармацевтическая композиция
|
JPH09507500A
(ja)
|
1994-01-13 |
1997-07-29 |
メルク シヤープ エンド ドーム リミテツド |
gem二置換アザシクロ系のタキキニン拮抗薬
|
WO1995020575A1
(en)
|
1994-01-28 |
1995-08-03 |
Merck Sharp & Dohme Limited |
Aralkylamino substituted azacyclic therapeutic agents
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
TW385308B
(en)
|
1994-03-04 |
2000-03-21 |
Merck & Co Inc |
Prodrugs of morpholine tachykinin receptor antagonists
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
CN1151156A
(zh)
|
1994-03-15 |
1997-06-04 |
卫材株式会社 |
异戊二烯基转移酶抑制剂
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
RU95104898A
(ru)
|
1994-03-31 |
1996-12-27 |
Бристоль-Мейерз Сквибб Компани (US) |
Имидазолсодержащие ингибиторы фарнезид-протеинтрансферазы, способ лечения связанных с ней заболеваний
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
ZA953311B
(en)
|
1994-04-29 |
1996-10-24 |
Lilly Co Eli |
Non-peptidyl tachykinin receptor antagonists
|
US5747491A
(en)
|
1994-05-05 |
1998-05-05 |
Merck Sharp & Dohme Ltd. |
Morpholine derivatives and their use as antagonists of tachikinins
|
SK142696A3
(en)
|
1994-05-07 |
1997-06-04 |
Boehringer Ingelheim Kg |
Amino acids derivative, method for preparation thereof, pharmaceutical compositions containing said compounds (ii) and their use
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
EP0764163B1
(de)
|
1994-06-06 |
2001-10-10 |
Warner-Lambert Company |
Tachykinin (nk1) rezeptor antagonisten
|
CA2150992A1
(en)
|
1994-06-10 |
1995-12-11 |
Philip Arthur Hipskind |
Cyclohexyl tachykinin receptor antagonists
|
JPH10501259A
(ja)
|
1994-06-10 |
1998-02-03 |
ローン−プーラン・ロレ・ソシエテ・アノニム |
新規ファルネシルトランスフェラーゼインヒビター、それらの製造およびそれらを含む医薬組成物
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
NZ289652A
(en)
|
1994-07-12 |
1998-05-27 |
Lilly Co Eli |
(r)-3-(1h-indol-3-yl)-1-[n-(2-methoxybenzyl)acetylamino]-2-[n-(2-(4-( piperidin-1-yl)piperidin-1-yl)acetyl)amino]propane dihydrochloride trihydrate; non-peptidyl tachykinin receptor antagonistic medicaments
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
EP0776884B1
(de)
|
1994-08-11 |
2000-01-05 |
Banyu Pharmaceutical Co., Ltd. |
Substituierte amidderivate
|
AU3192495A
(en)
|
1994-08-12 |
1996-03-07 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
ATE201866T1
(de)
|
1994-08-15 |
2001-06-15 |
Merck Sharp & Dohme |
Morpholinderivate und ihre verwendung als therapeutische mittel
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
ATE177095T1
(de)
|
1994-08-25 |
1999-03-15 |
Merrell Pharma Inc |
Substituierte piperidine für die behandlung von allergischen krankheiten
|
ES2107118T3
(es)
|
1994-08-29 |
1997-11-16 |
Akzo Nobel Nv |
Procedimiento para la preparacion de diesteres cuaternarios.
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
US5935951A
(en)
|
1994-09-30 |
1999-08-10 |
Novartis Finance Corporation |
1-acyl-4-aliphatylaminopiperidine compounds
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP0709375B1
(de)
|
1994-10-25 |
2005-05-18 |
AstraZeneca AB |
Therapeutisch wirksame Heterocyclen
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
EP0740853B1
(de)
|
1994-11-22 |
1999-01-13 |
Koninklijke Philips Electronics N.V. |
Halbleiter mit einem träger auf dem ein substrat mit einem halbleiter-element mittels einer klebeschicht und ein leiterbahn-muster befestigt sind
|
EP0714891A1
(de)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterozyklische Tachykinin-Rezeptorantagonisten
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
WO1996017861A1
(en)
|
1994-12-09 |
1996-06-13 |
Warner-Lambert Company |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
IL116323A0
(en)
|
1994-12-13 |
1996-03-31 |
Sandoz Ag |
Tachykinin antagonists their preparation and pharmaceutical compositions containing them
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
EA000164B1
(ru)
|
1995-01-09 |
1998-10-29 |
Магла Интернэшнл Лтд. |
Состав для печати изображения на поверхности изделия из каучукового латекса, способ печати изображения и изделия из каучукового латекса
|
AU4437896A
(en)
|
1995-01-12 |
1996-07-31 |
Glaxo Group Limited |
Piperidine derivatives having tachykinin antagonist activity
|
WO1996021456A1
(en)
|
1995-01-12 |
1996-07-18 |
University Of Pittsburgh |
Inhibitors of prenyl transferases
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
TW394773B
(en)
|
1995-03-24 |
2000-06-21 |
Takeda Chemical Industries Ltd |
Cyclic compounds for antagonizing tachykinin receptor, substance p receptor and neurokinin a receptor, their production and pharmaceutical composition
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
AU5432696A
(en)
|
1995-04-07 |
1996-10-23 |
Pharmacopeia, Inc. |
Carbonyl-piperazinyl and piperidinil compounds which inhibit farnesyl protein transferase
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
CN1098255C
(zh)
|
1995-04-13 |
2003-01-08 |
阿温蒂斯药物公司 |
新的具有速激肽受体拮抗活性的取代的哌嗪衍生物
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
CA2222041A1
(en)
|
1995-05-25 |
1996-11-28 |
Fujisawa Pharmaceutical Co., Ltd. |
1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as neurokinin receptor antagonists
|
US5919780A
(en)
|
1995-06-16 |
1999-07-06 |
Warner Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
ES2155601T3
(es)
|
1995-07-07 |
2001-05-16 |
Pfizer |
Compuestos de benzolactama sustituidos como antagonistas de la sustancia p.
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
JP2002534955A
(ja)
|
1995-10-18 |
2002-10-15 |
メルク エンド カンパニー インコーポレーテッド |
シクロペンチルタキキニン受容体アンタゴニスト
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
DK0873123T3
(da)
|
1995-11-06 |
2003-08-04 |
Univ Pittsburgh |
Inhibitorer af protein-isoprenyltransferaser
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
JP4183099B2
(ja)
|
1995-11-17 |
2008-11-19 |
ゲゼルシャフト・フュア・ビオテヒノロジッシェ・フォルシュング・ミット・ベシュレンクテル・ハフツング(ゲー・ベー・エフ) |
エポチロンcおよびd、製造法ならびに組成物
|
WO1997018813A1
(en)
|
1995-11-22 |
1997-05-29 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US6060469A
(en)
|
1995-11-23 |
2000-05-09 |
Merck Sharp & Dohme Ltd. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
RU2135494C1
(ru)
|
1995-12-01 |
1999-08-27 |
Санкио Компани Лимитед |
Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина
|
SI0865440T1
(en)
|
1995-12-08 |
2002-08-31 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
AR005152A1
(es)
|
1995-12-22 |
1999-04-14 |
Schering Corp |
Amidas tricíclicas útiles para la inhibición de la función de la proteina-g, sus sales , una composición farmacéutica que las contienen y el uso de las mismas para la fabricación de un medicamento para el tratamiento de enfermedades proliferativas
|
US6008372A
(en)
|
1996-01-16 |
1999-12-28 |
Warner-Lambert Company |
Substituted dinaphthylmethyl and diheteroarylmethylacetyl histidine inhibitors of protein farnesyltransferase
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
AU715202B2
(en)
|
1996-04-03 |
2000-01-20 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
CN1098256C
(zh)
|
1996-04-12 |
2003-01-08 |
G·D·瑟尔公司 |
作为cox-2抑制剂前药的取代的苯磺酰胺衍生物
|
EE9800408A
(et)
|
1996-05-22 |
1999-06-15 |
Warner-Lambert Company |
Proteiinfarnesüültransferaasi inhibiitorid
|
AU709409B2
(en)
|
1996-07-15 |
1999-08-26 |
Bristol-Myers Squibb Company |
Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
JP4579351B2
(ja)
|
1996-12-03 |
2010-11-10 |
スローン−ケッタリング インスティトュート フォア キャンサー リサーチ |
エポチロンの合成とその中間体及びその類似物並びにその使用
|
WO1998029119A1
(en)
|
1996-12-30 |
1998-07-09 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
EP1003374A4
(de)
|
1996-12-30 |
2000-05-31 |
Merck & Co Inc |
Inhibitoren von farnesyl-protein-transferase
|
JP2002536968A
(ja)
|
1999-01-29 |
2002-11-05 |
イムクローン システムズ インコーポレイティド |
Kdrに特異的な抗体およびその使用
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
AU4972900A
(en)
|
1999-04-08 |
2000-11-14 |
Arch Development Corporation |
Use of anti-vegf antibody to enhance radiation in cancer therapy
|
EP1259494A4
(de)
|
2000-02-18 |
2004-09-15 |
Merck & Co Inc |
Aryloxyessigsäuren für diabetes und lipid-erkrankungen
|
DE60124684T2
(de)
|
2000-03-20 |
2007-09-13 |
Merck Sharp & Dohme Ltd., Hoddesdon |
Sulfonamido-substituierte verbrückte bicycloalkylderivative
|
GB0012671D0
(en)
|
2000-05-24 |
2000-07-19 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO2002018544A2
(en)
*
|
2000-08-31 |
2002-03-07 |
Loyola University Chicago |
Method and reagents for treatment of skin disorders by modulating the notch pathway
|
AU9287401A
(en)
|
2000-09-27 |
2002-04-08 |
Merck & Co Inc |
Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders
|
GB0025173D0
(en)
|
2000-10-13 |
2000-11-29 |
Merck Sharp & Dohme |
Therapeutic agents
|
ES2248397T3
(es)
|
2000-11-02 |
2006-03-16 |
MERCK SHARP & DOHME LTD. |
Sulfamidas como inhibidores de la gamma-secretasa.
|
UA74849C2
(en)
|
2000-11-17 |
2006-02-15 |
Lilly Co Eli |
Lactam
|
GB0108591D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB0108592D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
EP1379251B1
(de)
|
2001-04-10 |
2008-07-09 |
Merck & Co., Inc. |
Hemmstoffe der akt aktivität
|
US6958334B2
(en)
|
2001-04-10 |
2005-10-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
WO2002083675A2
(en)
|
2001-04-10 |
2002-10-24 |
Merck Sharp & Dohme Limited |
Inhibitors of akt activity
|
AU2002307163B2
(en)
|
2001-04-10 |
2006-06-29 |
Merck & Co., Inc. |
A method of treating cancer
|
GB0119152D0
(en)
|
2001-08-06 |
2001-09-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
EA006225B1
(ru)
|
2001-08-21 |
2005-10-27 |
Мерк Шарп Энд Домэ Лимитед |
Новые циклогексилсульфоны
|
EP1444209A4
(de)
|
2001-11-07 |
2005-02-16 |
Merck & Co Inc |
Inhibitoren mitotischer kinesine
|
ATE424388T1
(de)
|
2001-12-06 |
2009-03-15 |
Merck & Co Inc |
Mitotische kinesinhemmer
|
AU2002363960B2
(en)
|
2001-12-06 |
2008-07-10 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
WO2003050122A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
DE60234278D1
(de)
|
2001-12-06 |
2009-12-17 |
Merck & Co Inc |
Mitotische kinesin-hemmer
|
AU2002357053B2
(en)
|
2001-12-06 |
2008-05-15 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
CA2478068C
(en)
|
2002-03-08 |
2011-02-08 |
Merck & Co., Inc. |
Dihydropyrazole compounds useful for treating or preventing cancer
|
EP1496981A2
(de)
|
2002-04-08 |
2005-01-19 |
Merck & Co., Inc. |
Verfahren zur behandlung von krebs
|
AU2003226271B2
(en)
|
2002-04-08 |
2007-10-18 |
Merck Sharp & Dohme Corp. |
Fused quinoxaline derivatives as inhibitors of Akt activity
|
US20050130977A1
(en)
|
2002-04-08 |
2005-06-16 |
Lindsley Craig W. |
Inhibitors of akt activity
|
US7223738B2
(en)
|
2002-04-08 |
2007-05-29 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
JP4394959B2
(ja)
|
2002-04-08 |
2010-01-06 |
メルク エンド カムパニー インコーポレーテッド |
Akt活性の阻害剤
|
GB0209997D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB0209995D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO2003093252A1
(en)
|
2002-05-01 |
2003-11-13 |
Merck Sharp & Dohme Limited |
Heteroaryl substituted spirocyclic sulfamides for inhibition of gamma secretase
|
GB0209991D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
CA2485343A1
(en)
|
2002-05-23 |
2004-05-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
WO2003099211A2
(en)
|
2002-05-23 |
2003-12-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
ES2282647T3
(es)
|
2002-06-14 |
2007-10-16 |
MERCK & CO., INC. |
Inhibidores de cinesina mitotica.
|
BR0311784A
(pt)
|
2002-06-14 |
2005-03-08 |
Merck & Co Inc |
Composto, composição farmacêutica, métodos de tratar ou prevenir o câncer, de modular a formação do fuso mitótico e de inibir a cinesina mitótica e processo para fabricar uma composição farmacêutica
|
AU2003263963A1
(en)
|
2002-08-01 |
2004-02-23 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of |
Method of treating inflammatory arthropathies with suppressors of cpg oligonucleotides
|
GB0218041D0
(en)
|
2002-08-02 |
2002-09-11 |
Merck Sharp & Dohme |
Chemical process
|
GB0223038D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
GB0223039D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
GB0223040D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
WO2004037171A2
(en)
|
2002-10-18 |
2004-05-06 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
US20040102360A1
(en)
|
2002-10-30 |
2004-05-27 |
Barnett Stanley F. |
Combination therapy
|
DE60336576D1
(de)
|
2002-10-30 |
2011-05-12 |
Merck Sharp & Dohme |
Hemmer der akt aktivität
|
GB0225474D0
(en)
|
2002-11-01 |
2002-12-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB0225475D0
(en)
|
2002-11-01 |
2002-12-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
AU2003295843A1
(en)
|
2002-12-06 |
2004-06-30 |
Pharmacia Corporation |
Mitoneet polypeptide from mitochondrial membranes, modulators thereof, and methods of using the same
|
US7622489B2
(en)
|
2002-12-20 |
2009-11-24 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
WO2004058148A2
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
CN1777436A
(zh)
*
|
2003-02-18 |
2006-05-24 |
罗斯坎普研究有限责任公司 |
β和γ分泌酶抑制剂的抗血管生成和抗肿瘤性
|
US7135575B2
(en)
*
|
2003-03-03 |
2006-11-14 |
Array Biopharma, Inc. |
P38 inhibitors and methods of use thereof
|
GB0308318D0
(en)
|
2003-04-10 |
2003-05-14 |
Merck Sharp & Dohme |
Therapeutic agents
|
AU2004233827B2
(en)
|
2003-04-24 |
2009-05-28 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
WO2004096135A2
(en)
|
2003-04-24 |
2004-11-11 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
AU2004233826B2
(en)
|
2003-04-24 |
2009-08-13 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
CA2522431A1
(en)
|
2003-04-24 |
2004-11-11 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
EP1644346A1
(de)
|
2003-05-16 |
2006-04-12 |
MERCK SHARP & DOHME LTD. |
Cyclische sulfonamide zur inhibierung von gamma-sekretase
|
CA2686618A1
(en)
|
2003-07-17 |
2005-01-17 |
At&T Corp. |
Method and apparatus for windowing in entropy encoding
|
KR100536215B1
(ko)
|
2003-08-05 |
2005-12-12 |
삼성에스디아이 주식회사 |
플라즈마 디스플레이 패널
|
GB0318447D0
(en)
|
2003-08-05 |
2003-09-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
CN100548296C
(zh)
|
2003-08-13 |
2009-10-14 |
默克公司 |
有丝分裂驱动蛋白抑制剂
|
CN1835746A
(zh)
|
2003-08-15 |
2006-09-20 |
默克公司 |
有丝分裂驱动蛋白抑制剂
|
AU2004266232B2
(en)
|
2003-08-15 |
2008-07-03 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
PE20050730A1
(es)
|
2003-08-15 |
2005-09-20 |
Merck & Co Inc |
Derivados de 2,5-dihidropirrol 2,2-disustituidos como inhibidores de quinesinas mitoticas
|
EP1656146A4
(de)
|
2003-08-15 |
2009-04-15 |
Merck & Co Inc |
Inhibitoren von mitotischem kinesin
|
JP2007506715A
(ja)
|
2003-09-24 |
2007-03-22 |
メルク シャープ エンド ドーム リミテッド |
ガンマセクレターゼ阻害剤
|
US7294640B2
(en)
|
2004-02-06 |
2007-11-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
WO2005100356A1
(en)
|
2004-04-09 |
2005-10-27 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
DE602005026509D1
(de)
|
2004-04-09 |
2011-04-07 |
Merck Sharp & Dohme |
Hemmer der akt aktivität
|
US20080220416A1
(en)
|
2004-05-20 |
2008-09-11 |
The Board Of Trustees Of The University Of Illinoi |
Compositions for Inhibiting Cell Growth and Inducing Apoptosis in Cancer Cells and Methods of Use Thereof
|
US20070077245A1
(en)
*
|
2004-08-04 |
2007-04-05 |
The Brigham And Women's Hospital, Inc. |
NOTCH mutations leading to increased receptor signaling
|
AU2005302846A1
(en)
|
2004-11-10 |
2006-05-18 |
Hubrecht Laboratorium |
Treatment of an intestinal adenoma and/or adenocarcinoma by inhibition of notch pathway activation
|