ATE537260T1 - Terpen synthase/cyclase und olefin synthase sowie deren verwendung - Google Patents
Terpen synthase/cyclase und olefin synthase sowie deren verwendungInfo
- Publication number
- ATE537260T1 ATE537260T1 AT02700889T AT02700889T ATE537260T1 AT E537260 T1 ATE537260 T1 AT E537260T1 AT 02700889 T AT02700889 T AT 02700889T AT 02700889 T AT02700889 T AT 02700889T AT E537260 T1 ATE537260 T1 AT E537260T1
- Authority
- AT
- Austria
- Prior art keywords
- bio
- synthase
- fragrance
- flavor
- encoding
- Prior art date
Links
- 101710135150 (+)-T-muurolol synthase ((2E,6E)-farnesyl diphosphate cyclizing) Proteins 0.000 title 1
- 101710119400 Geranylfarnesyl diphosphate synthase Proteins 0.000 title 1
- 101710107752 Geranylgeranyl diphosphate synthase Proteins 0.000 title 1
- 150000001336 alkenes Chemical class 0.000 title 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 title 1
- 108010087432 terpene synthase Proteins 0.000 title 1
- 239000012681 biocontrol agent Substances 0.000 abstract 3
- 239000000796 flavoring agent Substances 0.000 abstract 3
- 235000019634 flavors Nutrition 0.000 abstract 3
- 239000003205 fragrance Substances 0.000 abstract 3
- VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VWFJDQUYCIWHTN-FBXUGWQNSA-N Farnesyl diphosphate Natural products CC(C)=CCC\C(C)=C/CC\C(C)=C/COP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-FBXUGWQNSA-N 0.000 abstract 2
- GVVPGTZRZFNKDS-YFHOEESVSA-N Geranyl diphosphate Natural products CC(C)=CCC\C(C)=C/COP(O)(=O)OP(O)(O)=O GVVPGTZRZFNKDS-YFHOEESVSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- GVVPGTZRZFNKDS-JXMROGBWSA-N geranyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O GVVPGTZRZFNKDS-JXMROGBWSA-N 0.000 abstract 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- FQTLCLSUCSAZDY-UHFFFAOYSA-N (+) E(S) nerolidol Natural products CC(C)=CCCC(C)=CCCC(C)(O)C=C FQTLCLSUCSAZDY-UHFFFAOYSA-N 0.000 abstract 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 abstract 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 abstract 1
- FQTLCLSUCSAZDY-ATGUSINASA-N Nerolidol Chemical compound CC(C)=CCC\C(C)=C\CC[C@](C)(O)C=C FQTLCLSUCSAZDY-ATGUSINASA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 229930007744 linalool Natural products 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229930003658 monoterpene Natural products 0.000 abstract 1
- 150000002773 monoterpene derivatives Chemical class 0.000 abstract 1
- 235000002577 monoterpenes Nutrition 0.000 abstract 1
- WASNIKZYIWZQIP-AWEZNQCLSA-N nerolidol Natural products CC(=CCCC(=CCC[C@@H](O)C=C)C)C WASNIKZYIWZQIP-AWEZNQCLSA-N 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229930004725 sesquiterpene Natural products 0.000 abstract 1
- 150000004354 sesquiterpene derivatives Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Pest Control & Pesticides (AREA)
- Medicinal Chemistry (AREA)
- Insects & Arthropods (AREA)
- Nutrition Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fats And Perfumes (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01200488A EP1231273A1 (de) | 2001-02-12 | 2001-02-12 | Terpen Synthase/Cyclase und Olefin Synthase sowie deren Verwendung |
| PCT/NL2002/000089 WO2002064764A2 (en) | 2001-02-12 | 2002-02-12 | Terpene synthase/cyclase and olefin synthase and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE537260T1 true ATE537260T1 (de) | 2011-12-15 |
Family
ID=8179877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02700889T ATE537260T1 (de) | 2001-02-12 | 2002-02-12 | Terpen synthase/cyclase und olefin synthase sowie deren verwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7453024B2 (de) |
| EP (2) | EP1231273A1 (de) |
| AT (1) | ATE537260T1 (de) |
| BR (1) | BR0207164A (de) |
| ES (1) | ES2379461T3 (de) |
| WO (1) | WO2002064764A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7939091B2 (en) * | 1999-08-06 | 2011-05-10 | Iowa State University Research Foundation, Inc. | Biorational repellents obtained from terpenoids for use against arthropods |
| DE10201458A1 (de) * | 2001-04-11 | 2002-10-17 | Adelbert Bacher | Intermediate und Enzyme des Mevalonat-unabhängigen Isoprenoidbiosyntheseweg |
| BRPI0314979B1 (pt) * | 2002-10-04 | 2019-10-22 | Firmenich & Cie | método de produção de um valenceno e microorganismo transgênico |
| NZ523384A (en) * | 2002-12-24 | 2005-12-23 | Horticulture & Food Res Inst | Enzymes and polynucleotides encoding the same |
| EP2388333A3 (de) * | 2003-06-19 | 2012-04-04 | Evolva SA | Verfahren zur Herstellung einer organischen Verbindung mit geringem Molekulargewicht in einer Zelle |
| RU2006122534A (ru) * | 2003-11-26 | 2008-01-10 | Фирмениш Са (Ch) | Сесквитерпен синтезы из пачулей |
| AU2003304604A1 (en) * | 2003-12-09 | 2005-06-29 | Firmenich Sa | Sesquiterpene synthases from patchouli |
| WO2006111924A2 (en) * | 2005-04-19 | 2006-10-26 | University Of Kentucky Research Foundation | Transformed plants accumulating terpenes |
| JP5430929B2 (ja) | 2005-06-17 | 2014-03-05 | フイルメニツヒ ソシエテ アノニム | 新規セスキテルペン合成酵素ならびにその使用方法 |
| EP2066778B1 (de) * | 2006-09-26 | 2016-01-27 | The Regents of The University of California | Herstellung von isoprenoiden und isoprenoidvorläufern |
| US20080241329A1 (en) * | 2007-03-28 | 2008-10-02 | Kraft Foods Holdings, Inc. | Antimicrobial composition and its use in ready-to-drink beverages |
| SG178735A1 (en) | 2007-06-01 | 2012-03-29 | Scripps Research Inst | High throughput screening of genetically modified photosynthetic organisms |
| WO2009005704A1 (en) * | 2007-07-03 | 2009-01-08 | The Regents Of The University Of California | Methods of increasing isoprenoid or isoprenoid precursor production |
| WO2009015079A1 (en) * | 2007-07-21 | 2009-01-29 | The Samuel Roberts Noble Foundation, Inc. | Modification of plant disease resistance |
| WO2009036087A1 (en) * | 2007-09-11 | 2009-03-19 | Sapphire Energy, Inc. | Methods of producing organic products with photosynthetic organisms and products and compositions thereof |
| CA2698801A1 (en) * | 2007-09-11 | 2009-03-19 | Sapphire Energy, Inc. | Molecule production by photosynthetic organisms |
| JP2011147432A (ja) * | 2009-12-25 | 2011-08-04 | Kirin Holdings Co Ltd | 新規のテルペン類合成酵素活性を有するタンパク質とそれをコードする遺伝子 |
| US9518282B2 (en) * | 2010-12-28 | 2016-12-13 | Suntory Holdings Limited | Method for utilizing monoterpene glycosyltransferase |
| JP2015516173A (ja) * | 2012-05-16 | 2015-06-11 | グリコス バイオテクノロジーズ インコーポレイテッドＧｌｙｃｏｓ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅｓ， Ｉｎｃ． | イソプレン生産用微生物およびプロセス |
| WO2016008885A1 (en) * | 2014-07-14 | 2016-01-21 | Photanol B.V. | Biosynthesis of sesquiterpenes in cyanobacteria |
| WO2016064347A1 (en) | 2014-10-22 | 2016-04-28 | Temasek Life Sciences Laboratory Limited | Terpene synthases from ylang ylang (cananga odorata var. fruticosa) |
| GB201500377D0 (en) | 2015-01-09 | 2015-02-25 | Micromass Ltd | Lock mass using chromatographic peaks |
| AU2017252575B2 (en) | 2016-04-22 | 2021-11-18 | Spoke Sciences, Inc. | Fast-acting plant-based medicinal compounds and nutritional supplements |
| EA201892396A1 (ru) | 2016-12-02 | 2019-04-30 | Ресептор Лайф Сайенсиз, Инк. | Быстродействующие растительные лекарственные соединения и биологически активные добавки |
| CN108893482B (zh) * | 2018-06-22 | 2021-11-05 | 中国医学科学院药用植物研究所 | 丹参萜类合酶基因SmTPS8、其克隆引物、表达载体、催化产物及应用 |
| JP7566336B2 (ja) | 2018-11-19 | 2024-10-15 | スポーク・サイエンシズ・インコーポレイテッド | カンナビノイド由来組成物の吸収変動を低減するｎ－アシル化脂肪アミノ酸 |
| EP3739055A1 (de) * | 2019-05-15 | 2020-11-18 | Symrise AG | Biotechnologische herstellung von aromastoffen aus johannisbeertrester |
| CN113841707B (zh) * | 2021-10-26 | 2022-07-05 | 中国热带农业科学院环境与植物保护研究所 | 反式法尼醇作为增效剂在防治荔枝霜疫病中的应用 |
| CN120167011A (zh) * | 2022-11-14 | 2025-06-17 | 新加坡科技研究局 | 类异戊二烯的生物合成 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4041185A (en) * | 1975-08-25 | 1977-08-09 | General Foods Corporation | Blueberry flavor |
| US4775534A (en) | 1986-02-05 | 1988-10-04 | Fermone Chemicals, Inc. | Miticidal composition and method for controlling spider mite populations |
| US5116602A (en) * | 1989-09-27 | 1992-05-26 | Colgate-Palmolive Company | Antiplaque oral compositions |
| EP0506763B1 (de) | 1989-12-22 | 1999-06-02 | E.I. Du Pont De Nemours And Company | Ortsspezifische rekombination von dns in pflanzenzellen |
| US5196200A (en) * | 1991-04-25 | 1993-03-23 | International Flavors & Fragrances Inc. | Bisabolene-containing composition, process for preparing same, organoleptic uses thereof and uses thereof as insect repellent |
| US6291745B1 (en) * | 1993-04-02 | 2001-09-18 | Pioneer Hi-Bred International, Inc. | Limonene and other downstream metabolites of geranyl pyrophosphate for insect control in plants |
| CA2222023C (en) | 1995-05-24 | 1999-11-23 | Terry E. Meyer | Corn rootworm control via formation of limonene in transgenic plants |
| WO1997015584A2 (en) * | 1995-10-12 | 1997-05-01 | The Regents Of The University Of Michigan | Use of linalool synthase in genetic engineering of scent production |
| US5849526A (en) * | 1996-10-15 | 1998-12-15 | The Regents Of The University Of Michigan | Use of linalool synthase in genetic engineering of scent production |
| CA2302873C (en) * | 1997-09-02 | 2005-01-25 | Washington State University Research Foundation | Nucleic and amino acid sequences for a novel transketolase from (mentha piperita) |
| US6265639B1 (en) * | 1998-01-22 | 2001-07-24 | Washington State University Foundation | Gymnosperm nucleic acid molecules encoding sesquiterpene synthases and methods of use |
| EP0982404A1 (de) | 1998-08-27 | 2000-03-01 | Wallaart, Thorvald Eelco | DNS, die für Amorpha-4,11-diensynthase codiert |
-
2001
- 2001-02-12 EP EP01200488A patent/EP1231273A1/de not_active Withdrawn
-
2002
- 2002-02-12 AT AT02700889T patent/ATE537260T1/de active
- 2002-02-12 EP EP02700889A patent/EP1379663B1/de not_active Expired - Lifetime
- 2002-02-12 BR BR0207164-9A patent/BR0207164A/pt not_active Application Discontinuation
- 2002-02-12 ES ES02700889T patent/ES2379461T3/es not_active Expired - Lifetime
- 2002-02-12 WO PCT/NL2002/000089 patent/WO2002064764A2/en not_active Application Discontinuation
-
2003
- 2003-08-05 US US10/635,223 patent/US7453024B2/en not_active Expired - Fee Related
-
2008
- 2008-11-17 US US12/272,329 patent/US8338663B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1379663B1 (de) | 2011-12-14 |
| US7453024B2 (en) | 2008-11-18 |
| US20100144893A1 (en) | 2010-06-10 |
| WO2002064764A3 (en) | 2003-12-31 |
| ES2379461T3 (es) | 2012-04-26 |
| EP1231273A1 (de) | 2002-08-14 |
| WO2002064764A8 (en) | 2003-11-06 |
| US20040161819A1 (en) | 2004-08-19 |
| WO2002064764A2 (en) | 2002-08-22 |
| EP1379663A2 (de) | 2004-01-14 |
| US8338663B2 (en) | 2012-12-25 |
| BR0207164A (pt) | 2004-02-10 |
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