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ATE5066T1 - 2-ALKYL-5-HYDROXY-1,4-NAPHTHOCHINONES, PROCESSES FOR THEIR PREPARATION AND MEDICATIONS CONTAINING THESE COMPOUNDS. - Google Patents

2-ALKYL-5-HYDROXY-1,4-NAPHTHOCHINONES, PROCESSES FOR THEIR PREPARATION AND MEDICATIONS CONTAINING THESE COMPOUNDS.

Info

Publication number
ATE5066T1
ATE5066T1 AT81101380T AT81101380T ATE5066T1 AT E5066 T1 ATE5066 T1 AT E5066T1 AT 81101380 T AT81101380 T AT 81101380T AT 81101380 T AT81101380 T AT 81101380T AT E5066 T1 ATE5066 T1 AT E5066T1
Authority
AT
Austria
Prior art keywords
hydroxy
alkyl
naphthochinones
compounds
processes
Prior art date
Application number
AT81101380T
Other languages
German (de)
Inventor
Gotthard Prof. Dr. Freie Univer Wurm
2+4 Koenigin-Luise-Strasse
Original Assignee
Zyma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma Gmbh filed Critical Zyma Gmbh
Application granted granted Critical
Publication of ATE5066T1 publication Critical patent/ATE5066T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C07C46/08—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)

Abstract

1. 2-Alkyl-5-hydroxy-1,4-naphthoquinones of the general formula I see diagramm : EP0036502,P9,F1 wherein Y denotes the methyl, ethyl, n-propyl, isopropyl or tert.-butyl group.
AT81101380T 1980-02-27 1981-02-25 2-ALKYL-5-HYDROXY-1,4-NAPHTHOCHINONES, PROCESSES FOR THEIR PREPARATION AND MEDICATIONS CONTAINING THESE COMPOUNDS. ATE5066T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3007367A DE3007367C2 (en) 1980-02-27 1980-02-27 2-alkyl-5-hydroxy-1,4-naphthoquinones, processes for their preparation and pharmaceuticals
EP81101380A EP0036502B1 (en) 1980-02-27 1981-02-25 2-alkyl-5-hydroxy-1,4-naphthoquinones, process for their manufacture and pharmaceutical preparations containing these compounds

Publications (1)

Publication Number Publication Date
ATE5066T1 true ATE5066T1 (en) 1983-11-15

Family

ID=6095701

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81101380T ATE5066T1 (en) 1980-02-27 1981-02-25 2-ALKYL-5-HYDROXY-1,4-NAPHTHOCHINONES, PROCESSES FOR THEIR PREPARATION AND MEDICATIONS CONTAINING THESE COMPOUNDS.

Country Status (6)

Country Link
EP (1) EP0036502B1 (en)
AT (1) ATE5066T1 (en)
DE (2) DE3007367C2 (en)
ES (1) ES8301866A1 (en)
HU (1) HU188282B (en)
ZA (1) ZA811227B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431236A1 (en) * 1984-08-24 1986-02-27 Carnivora-Deutschland GmbH, 7109 Jagsthausen USE OF 1,4-NAPHTHOQUINONE DERIVATIVES IN LOW CONCENTRATIONS FOR IMMUNE STIMULATION
ZA863425B (en) * 1985-05-08 1988-01-27 Du Pont 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US4833164A (en) 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2572946A (en) * 1949-11-19 1951-10-30 Du Pont Composition comprising 2-aliphatic-3-hydroxy-1, 4 napthoquinone and method for controlling mites and aphids
US3578686A (en) * 1968-04-26 1971-05-11 Sterling Drug Inc 2-hydroxy - 3 -((3,3,5-trimethylcyclohexyl)-alkyl) - 1,4-naphthoquinones and their preparation

Also Published As

Publication number Publication date
DE3007367C2 (en) 1982-07-08
ES499847A0 (en) 1983-01-01
DE3161204D1 (en) 1983-11-24
EP0036502A1 (en) 1981-09-30
ZA811227B (en) 1982-03-31
EP0036502B1 (en) 1983-10-19
HU188282B (en) 1986-03-28
ES8301866A1 (en) 1983-01-01
DE3007367A1 (en) 1981-09-03

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Legal Events

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