ATE506342T1 - Ein verfahren zur herstellung von tolterodin - Google Patents
Ein verfahren zur herstellung von tolterodinInfo
- Publication number
- ATE506342T1 ATE506342T1 AT06002234T AT06002234T ATE506342T1 AT E506342 T1 ATE506342 T1 AT E506342T1 AT 06002234 T AT06002234 T AT 06002234T AT 06002234 T AT06002234 T AT 06002234T AT E506342 T1 ATE506342 T1 AT E506342T1
- Authority
- AT
- Austria
- Prior art keywords
- tolterodine
- producing
- producing tolterodine
- preparation
- diisopropyi
- Prior art date
Links
- OOGJQPCLVADCPB-HXUWFJFHSA-N tolterodine Chemical compound C1([C@@H](CCN(C(C)C)C(C)C)C=2C(=CC=C(C)C=2)O)=CC=CC=C1 OOGJQPCLVADCPB-HXUWFJFHSA-N 0.000 title abstract 2
- 229960004045 tolterodine Drugs 0.000 title abstract 2
- BDIAUFOIMFAIPU-UHFFFAOYSA-N valepotriate Natural products CC(C)CC(=O)OC1C=C(C(=COC2OC(=O)CC(C)C)COC(C)=O)C2C11CO1 BDIAUFOIMFAIPU-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C07C69/736—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000249A ITMI20050249A1 (it) | 2005-02-18 | 2005-02-18 | Procedimento per la preparazione di tolterodina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE506342T1 true ATE506342T1 (de) | 2011-05-15 |
Family
ID=35945084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06002234T ATE506342T1 (de) | 2005-02-18 | 2006-02-03 | Ein verfahren zur herstellung von tolterodin |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7335793B2 (de) |
| EP (1) | EP1693361B1 (de) |
| JP (1) | JP2006225391A (de) |
| AT (1) | ATE506342T1 (de) |
| CA (1) | CA2535667A1 (de) |
| DE (1) | DE602006021355D1 (de) |
| ES (1) | ES2361330T3 (de) |
| IT (1) | ITMI20050249A1 (de) |
| PT (1) | PT1693361E (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR057333A1 (es) * | 2005-05-27 | 2007-11-28 | Medichem Sa | Proceso para la preparacion de 3,3-diarilpropilaminas |
| ITMI20060984A1 (it) * | 2006-05-18 | 2007-11-19 | Dipharma Spa | Procedimento per la preparazione di arilossipropilammine |
| ITMI20062449A1 (it) | 2006-12-19 | 2008-06-20 | Dipharma Spa | Forma cristallina di rabeprazolo sodico |
| WO2008081477A1 (en) * | 2007-01-04 | 2008-07-10 | Natco Pharma Limited | 3-aryloxy 3-substituted propanamines |
| EP2175843B1 (de) | 2007-08-08 | 2014-10-08 | Inventia Healthcare Private Limited | Tolterodinhaltige zusammensetzungen mit verzögerter freisetzung |
| WO2010046801A2 (en) * | 2008-10-21 | 2010-04-29 | Alembic Limited | A process for the preparation of tolterodine tartrate |
| EP2476665A1 (de) * | 2011-01-17 | 2012-07-18 | Cambrex Profarmaco Milano S.r.l. | Verfahren zur Herstellung von N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl-Propylamin und seine Salze aus einem neuartigen Zwischenstoffs |
| WO2012098044A1 (en) * | 2011-01-17 | 2012-07-26 | Cambrex Profarmaco Milano S.R.L. | Process for the preparation of n,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8800207D0 (sv) | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| US5382600A (en) | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
| CN1245377C (zh) | 2004-08-16 | 2006-03-15 | 鲁南制药集团股份有限公司 | 托特罗定及其酒石酸盐的制备方法 |
| ES2268987B1 (es) | 2005-08-05 | 2008-02-01 | Ragactives, S.L. | Procedimiento para la obtencion de 3,3-difenilpropilaminas. |
-
2005
- 2005-02-18 IT IT000249A patent/ITMI20050249A1/it unknown
-
2006
- 2006-02-03 PT PT06002234T patent/PT1693361E/pt unknown
- 2006-02-03 ES ES06002234T patent/ES2361330T3/es active Active
- 2006-02-03 AT AT06002234T patent/ATE506342T1/de active
- 2006-02-03 DE DE602006021355T patent/DE602006021355D1/de active Active
- 2006-02-03 EP EP06002234A patent/EP1693361B1/de not_active Not-in-force
- 2006-02-09 CA CA002535667A patent/CA2535667A1/en not_active Abandoned
- 2006-02-17 JP JP2006041069A patent/JP2006225391A/ja active Pending
- 2006-02-21 US US11/356,953 patent/US7335793B2/en not_active Expired - Fee Related
-
2007
- 2007-12-14 US US12/000,587 patent/US7420091B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI20050249A1 (it) | 2006-08-19 |
| JP2006225391A (ja) | 2006-08-31 |
| US7420091B2 (en) | 2008-09-02 |
| US7335793B2 (en) | 2008-02-26 |
| EP1693361A1 (de) | 2006-08-23 |
| DE602006021355D1 (de) | 2011-06-01 |
| PT1693361E (pt) | 2011-05-16 |
| US20060189827A1 (en) | 2006-08-24 |
| ES2361330T3 (es) | 2011-06-16 |
| EP1693361B1 (de) | 2011-04-20 |
| US20080097127A1 (en) | 2008-04-24 |
| CA2535667A1 (en) | 2006-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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