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ATE499438T1 - Verfahren zum retten der rna-viren - Google Patents

Verfahren zum retten der rna-viren

Info

Publication number
ATE499438T1
ATE499438T1 AT99927175T AT99927175T ATE499438T1 AT E499438 T1 ATE499438 T1 AT E499438T1 AT 99927175 T AT99927175 T AT 99927175T AT 99927175 T AT99927175 T AT 99927175T AT E499438 T1 ATE499438 T1 AT E499438T1
Authority
AT
Austria
Prior art keywords
virus
recombinant virus
producing
viruses
mononegavirales
Prior art date
Application number
AT99927175T
Other languages
English (en)
Inventor
Christopher Parks
Mohinderjit Sidhu
Stephen Udem
Gerald Kovacs
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE499438T1 publication Critical patent/ATE499438T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
AT99927175T 1998-06-03 1999-06-03 Verfahren zum retten der rna-viren ATE499438T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8780098P 1998-06-03 1998-06-03
PCT/US1999/012292 WO1999063064A1 (en) 1998-06-03 1999-06-03 Novel methods for rescue of rna viruses

Publications (1)

Publication Number Publication Date
ATE499438T1 true ATE499438T1 (de) 2011-03-15

Family

ID=22207342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99927175T ATE499438T1 (de) 1998-06-03 1999-06-03 Verfahren zum retten der rna-viren

Country Status (14)

Country Link
EP (2) EP1995310B1 (de)
JP (1) JP4625915B2 (de)
KR (2) KR100579662B1 (de)
CN (1) CN1196780C (de)
AT (1) ATE499438T1 (de)
AU (1) AU761234B2 (de)
BR (1) BR9910929A (de)
CA (1) CA2333313C (de)
DE (1) DE69943215D1 (de)
DK (1) DK1090108T3 (de)
ES (1) ES2358315T3 (de)
IL (3) IL140033A0 (de)
MX (1) MX228492B (de)
WO (1) WO1999063064A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7465574B2 (en) 1994-09-30 2008-12-16 Medimmune, Llc Recombinant RSV virus expression systems and vaccines
US6830748B1 (en) 1997-09-26 2004-12-14 Medimmune Vaccines, Inc. Recombinant RSV virus expression systems and vaccines
US6495360B1 (en) * 1999-05-28 2002-12-17 Photogen, Inc. Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins
US7361496B1 (en) 2000-08-02 2008-04-22 Wyeth Rescue of mumps virus from cDNA
EP2110382A1 (de) * 2002-06-20 2009-10-21 Institut Pasteur Infektiöse cDNA eines verbesserten Vakzinstamms des Masernvirus Verwendung für immunogene Zusammensetzungen
MXPA05013141A (es) 2003-06-09 2006-03-17 Wyeth Corp Metodo mejorado para la recuperacion de arn virus de cadena negativa, no segmentados, a partir de adnc.
PL2491117T3 (pl) † 2009-10-20 2014-05-30 Novartis Ag Udoskonalone sposoby odzyskiwania wirusa wykorzystujące odwrotną genetykę
EP2780034A1 (de) 2011-11-14 2014-09-24 Crucell Holland B.V. Heterologe prime-boost-impfung mit auf masernviren basierten impfstoffen
CN102807989B (zh) * 2012-08-01 2014-04-23 中国人民解放军军事医学科学院军事兽医研究所 犬科和/或猫科动物疫病重组活载体疫苗的制备方法
LT3274447T (lt) * 2015-03-27 2020-02-10 Cadila Healthcare Limited Rekombinantinio kiaulytės viruso jeryl lynn 2 pagrindo vakcina
CN105039388B (zh) * 2015-06-30 2019-06-18 浙江大学 重组单链负义植物病毒侵染性克隆构建方法及质粒和病毒
CN107058359B (zh) * 2017-04-14 2019-08-13 北京交通大学 一种抗呼吸道合胞病毒药物的高通量筛选方法和应用
US20200124505A1 (en) * 2017-05-09 2020-04-23 Ultragenyx Pharmaceutical Inc. Scalable method for producing transfection reagents
CN111849927B (zh) * 2020-06-28 2022-07-08 浙江大学 高效产生重组不分节段负义rna病毒的方法及重组病毒
CN117625688B (zh) * 2024-01-26 2024-04-30 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） B亚型禽偏肺病毒反向遗传操作系统及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2953535B2 (ja) * 1989-02-14 1999-09-27 マサチユセツツ・インスチチユート・オブ・テクノロジー プリン代謝酵素の活性が増加した細胞の形質転換の阻害
DE69233158T2 (de) * 1991-03-07 2004-05-13 Connaught Technology Corp., Greenville Gentechnologisch hergestellter stamm für impfstoffe
JPH06237773A (ja) * 1992-12-22 1994-08-30 Tonen Corp ポックスウイルスのａ型封入体（ａｔｉ）プロモーター及び前期プロモーターを含んで成る外来遺伝子発現ベクター
DK0780475T4 (da) 1995-08-09 2006-10-23 Schweiz Serum & Impfinst Fremgangsmåde til fremstilling af infektiöse negativ-streng RNA-virus
US6264957B1 (en) * 1995-09-27 2001-07-24 The United States Of America As Represented By The Department Of Health And Human Services Product of infectious respiratory syncytial virus from cloned nucleotide sequences
WO1998013501A2 (en) * 1996-09-27 1998-04-02 American Cyanamid Company 3' genomic promoter region and polymerase gene mutations responsible for attenuation in viruses of the order designated mononegavirales
US5871803A (en) 1997-05-30 1999-02-16 Campbell Soup Company Salt flavor enhancing compositions, food products including such compositions, and methods for preparing such products

Also Published As

Publication number Publication date
EP1090108B1 (de) 2011-02-23
MX228492B (es) 2005-06-14
EP1995310A1 (de) 2008-11-26
AU761234B2 (en) 2003-05-29
CN1303426A (zh) 2001-07-11
DE69943215D1 (de) 2011-04-07
KR100579662B1 (ko) 2006-05-12
BR9910929A (pt) 2001-02-20
IL182512A0 (en) 2007-09-20
CN1196780C (zh) 2005-04-13
IL140033A (en) 2010-05-17
KR20010052498A (ko) 2001-06-25
KR20060021943A (ko) 2006-03-08
CA2333313A1 (en) 1999-12-09
AU4414499A (en) 1999-12-20
CA2333313C (en) 2011-11-08
JP4625915B2 (ja) 2011-02-02
JP2002517189A (ja) 2002-06-18
IL140033A0 (en) 2002-02-10
DK1090108T3 (da) 2011-04-26
IL182512A (en) 2012-07-31
KR100619319B1 (ko) 2006-09-06
EP1995310B1 (de) 2013-04-24
MXPA00011420A (es) 2001-04-01
EP1090108A1 (de) 2001-04-11
WO1999063064A1 (en) 1999-12-09
ES2358315T3 (es) 2011-05-09

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