ATE498418T1 - Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahren - Google Patents
Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahrenInfo
- Publication number
- ATE498418T1 ATE498418T1 AT02766341T AT02766341T ATE498418T1 AT E498418 T1 ATE498418 T1 AT E498418T1 AT 02766341 T AT02766341 T AT 02766341T AT 02766341 T AT02766341 T AT 02766341T AT E498418 T1 ATE498418 T1 AT E498418T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- gas pressure
- pressure actuated
- associated systems
- microneedle assemblies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32385201P | 2001-09-21 | 2001-09-21 | |
PCT/US2002/030117 WO2003024508A2 (en) | 2001-09-21 | 2002-09-23 | Gas pressure actuated microneedle arrays, and systems and methods relating to same |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE498418T1 true ATE498418T1 (de) | 2011-03-15 |
Family
ID=23260996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02766341T ATE498418T1 (de) | 2001-09-21 | 2002-09-23 | Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahren |
Country Status (7)
Country | Link |
---|---|
US (1) | US8920375B2 (de) |
EP (1) | EP1471953B1 (de) |
AT (1) | ATE498418T1 (de) |
AU (1) | AU2002330083A1 (de) |
CA (1) | CA2499838C (de) |
DE (1) | DE60239229D1 (de) |
WO (1) | WO2003024508A2 (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1469903A2 (de) * | 2001-09-28 | 2004-10-27 | BioValve Technologies, Inc. | Mikronadel mit membran |
US7415299B2 (en) * | 2003-04-18 | 2008-08-19 | The Regents Of The University Of California | Monitoring method and/or apparatus |
CA2523267C (en) | 2003-04-23 | 2013-09-03 | Biovalve Technologies, Inc. | Hydraulically actuated pump for long duration medicament administration |
US20080226699A1 (en) * | 2003-11-28 | 2008-09-18 | Acrux Dds Pty Ltd | Method and System for Rapid Transdermal Administration |
WO2005065765A1 (en) * | 2003-12-29 | 2005-07-21 | 3M Innovative Properties Company | Medical devices and kits including same |
US9089636B2 (en) | 2004-07-02 | 2015-07-28 | Valeritas, Inc. | Methods and devices for delivering GLP-1 and uses thereof |
ES2463818T3 (es) | 2004-08-16 | 2014-05-29 | Functional Microstructures Limited | Dispositivo que se aplicará a una barrera biológica |
JP2008520369A (ja) | 2004-11-18 | 2008-06-19 | スリーエム イノベイティブ プロパティズ カンパニー | 目立たないマイクロニードルアレイアプリケーター |
CN101060882B (zh) | 2004-11-18 | 2010-06-16 | 3M创新有限公司 | 微针阵列施放器和保持器 |
US10035008B2 (en) | 2005-04-07 | 2018-07-31 | 3M Innovative Properties Company | System and method for tool feedback sensing |
WO2007002523A2 (en) | 2005-06-24 | 2007-01-04 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
EP2474338B1 (de) * | 2005-06-27 | 2013-07-24 | 3M Innovative Properties Company | Vorrichtung zum Aufbringen einer Mikronadelanordnung |
US20070004989A1 (en) * | 2005-06-29 | 2007-01-04 | Parvinder Dhillon | Device for transdermal sampling |
US7186158B1 (en) * | 2005-12-07 | 2007-03-06 | Barber Gerald L | Life saving necklace |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
CA2646324C (en) | 2006-03-30 | 2016-06-07 | Valeritas, Llc | Multi-cartridge fluid delivery device |
US9119945B2 (en) * | 2006-04-20 | 2015-09-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2008079440A2 (en) | 2006-07-10 | 2008-07-03 | Medipacs, Inc. | Super elastic epoxy hydrogel |
KR100793615B1 (ko) * | 2006-07-21 | 2008-01-10 | 연세대학교 산학협력단 | 생분해성 솔리드 마이크로니들 및 이의 제조방법 |
AU2007303821B9 (en) | 2006-10-05 | 2013-06-20 | Technion Research & Development Foundation Ltd. | Microtubes and methods of producing same |
US9096845B2 (en) | 2007-08-29 | 2015-08-04 | Technion Research & Development Foundation Limited | Encapsulation of bacteria and viruses in electrospun fibers |
WO2009073734A2 (en) | 2007-12-03 | 2009-06-11 | Medipacs, Inc. | Fluid metering device |
US9469919B2 (en) | 2008-02-21 | 2016-10-18 | Technion Research & Development Foundation Ltd. | Method of attaching a cell-of-interest to a microtube |
US20100256524A1 (en) | 2009-03-02 | 2010-10-07 | Seventh Sense Biosystems, Inc. | Techniques and devices associated with blood sampling |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
WO2012018486A2 (en) | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
US8827971B2 (en) | 2011-04-29 | 2014-09-09 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving fluids |
US9238102B2 (en) | 2009-09-10 | 2016-01-19 | Medipacs, Inc. | Low profile actuator and improved method of caregiver controlled administration of therapeutics |
US9500186B2 (en) | 2010-02-01 | 2016-11-22 | Medipacs, Inc. | High surface area polymer actuator with gas mitigating components |
CN102985131B (zh) | 2010-04-28 | 2016-06-29 | 金伯利-克拉克环球有限公司 | 用于递送siRNA的医疗装置 |
RU2585159C2 (ru) | 2010-04-28 | 2016-05-27 | Кимберли-Кларк Ворлдвайд, Инк. | Устройство доставки лекарственного средства, применяемого при ревматоидном артрите |
KR101790815B1 (ko) | 2010-04-28 | 2017-10-26 | 킴벌리-클라크 월드와이드, 인크. | 세포성 상호작용이 향상된 나노패턴화 의료 기구 |
WO2012046149A1 (en) | 2010-04-28 | 2012-04-12 | Kimberly-Clark Worldwide, Inc. | Method for increasing permeability of an epithelial barrier |
US9125625B2 (en) | 2010-06-10 | 2015-09-08 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
US20120016308A1 (en) | 2010-07-16 | 2012-01-19 | Seventh Sense Biosystems, Inc. | Low-pressure packaging for fluid devices |
US20120039809A1 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
JP5996544B2 (ja) | 2010-10-15 | 2016-09-21 | クリアサイド・バイオメディカル・インコーポレーテッドClearside Biomedical Incorporated | 眼球アクセス用装置 |
US8668675B2 (en) | 2010-11-03 | 2014-03-11 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
JP6055773B2 (ja) | 2010-11-09 | 2016-12-27 | セブンス センス バイオシステムズ,インコーポレーテッド | 血液サンプリングのためのシステムおよびインターフェース |
EP3235429B1 (de) | 2011-04-29 | 2023-06-07 | YourBio Health, Inc. | Vorrichtungen und verfahren zur sammlung von blut eines patienten |
EP3106092A3 (de) | 2011-04-29 | 2017-03-08 | Seventh Sense Biosystems, Inc. | Systeme und verfahren zur flüssigkeitsentnahme aus einer person |
US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
WO2013058879A2 (en) | 2011-09-02 | 2013-04-25 | The Regents Of The University Of California | Microneedle arrays for biosensing and drug delivery |
EP2771059B1 (de) | 2011-10-27 | 2019-07-17 | Sorrento Therapeutics, Inc. | Transdermale freisetzung von hochviskosen bioaktiven wirkstoffen |
JP6535464B2 (ja) | 2011-10-27 | 2019-06-26 | ソレント・セラピューティクス・インコーポレイテッド | 生理活性薬剤の送達のための移植可能な装置 |
US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
CN104302689A (zh) | 2012-03-14 | 2015-01-21 | 麦德医像公司 | 含有过量活性分子的智能聚合物材料 |
JP6487848B2 (ja) | 2012-11-08 | 2019-03-20 | クリアサイド バイオメディカル,インコーポレイテッド | ヒト被験体における眼部障害の処置のための方法およびデバイス |
CN109621083B (zh) | 2013-02-28 | 2022-03-22 | 索伦托治疗有限公司 | 药物递送装置 |
WO2014132239A1 (en) | 2013-02-28 | 2014-09-04 | Kimberly-Clark Worldwide, Inc. | Drug delivery device |
CA3121759C (en) | 2013-05-03 | 2024-01-02 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
US11185271B2 (en) | 2013-09-13 | 2021-11-30 | University Of Utah Research Foundation | Methods of making micro-molded electrodes and arrays |
EP3157598A4 (de) | 2014-06-20 | 2018-05-16 | Clearside Biomedical, Inc. | Kanüle mit veränderlichem durchmesser und verfahren zur steuerung der einsatztiefe zur medikamentenabgabe |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
KR101667216B1 (ko) * | 2015-06-18 | 2016-10-18 | 방철환 | 약물 주입 장치 |
WO2017139375A1 (en) | 2016-02-10 | 2017-08-17 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
CA3062845A1 (en) | 2016-05-02 | 2017-11-09 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
CN110177527B (zh) | 2016-08-12 | 2022-02-01 | 科尼尔赛德生物医学公司 | 用于调节药剂递送用针的插入深度的装置和方法 |
US12109032B1 (en) | 2017-03-11 | 2024-10-08 | Biolinq Incorporated | Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure |
US11045142B1 (en) | 2017-04-29 | 2021-06-29 | Biolinq, Inc. | Heterogeneous integration of silicon-fabricated solid microneedle sensors and CMOS circuitry |
WO2018204515A1 (en) | 2017-05-02 | 2018-11-08 | Georgia Tech Research Corporation | Targeted drug delivery methods using a microneedle |
CN108379724A (zh) * | 2018-01-31 | 2018-08-10 | 余道逍 | 一种医疗用夜间加湿系统及其控制方法 |
CN110478613B (zh) | 2019-08-22 | 2022-08-09 | 京东方科技集团股份有限公司 | 递送制剂的器件、设备及器件中针头阵列的制备方法 |
CN110772376A (zh) * | 2019-11-20 | 2020-02-11 | 韩熠 | 一种用于婴幼儿及儿童的医用眼贴及其制备方法 |
WO2021119347A1 (en) * | 2019-12-12 | 2021-06-17 | The Regents Of The University Of California | Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy |
US11202753B1 (en) * | 2020-03-06 | 2021-12-21 | Aquavit Pharmaceuticals, Inc. | Systems and methods for generating immune responses in subjects using microchannel delivery devices |
JP2023523952A (ja) | 2020-04-28 | 2023-06-08 | ティコナ・エルエルシー | マイクロニードルアセンブリ |
ES2974786T3 (es) | 2020-07-29 | 2024-07-01 | Biolinq Incorporated | Sistema de monitorización continua de analitos con matriz de microagujas |
DE102020129916A1 (de) * | 2020-11-12 | 2022-05-12 | Lts Lohmann Therapie-Systeme Ag. | Interdermales Wirkstoffabgabesystem |
US12161832B2 (en) | 2021-03-01 | 2024-12-10 | Deka Products Limited Partnership | Medical agent dispensing systems, methods, and apparatuses |
CN116113454B (zh) | 2021-05-08 | 2024-05-24 | 比奥林股份有限公司 | 基于微针阵列的连续分析物监测装置的故障检测 |
US20230178201A1 (en) * | 2021-12-07 | 2023-06-08 | Umang JAIN | Methods and apparatuses for opioid overdose prevention |
CN114870236B (zh) * | 2022-03-23 | 2024-05-03 | 浙江工业大学 | 一种基于气动加载的微针进针器 |
Family Cites Families (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3123212A (en) * | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
USRE25637E (en) * | 1964-09-08 | Means for vaccinating | ||
US2893392A (en) * | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
GB885036A (en) * | 1958-12-10 | 1961-12-20 | Allen & Hanburys Ltd | Improvements relating to surgical multiple puncture devices |
US3034507A (en) * | 1960-05-10 | 1962-05-15 | American Cyanamid Co | Intracutaneous injection device |
US3136314A (en) * | 1960-08-01 | 1964-06-09 | Kravitz Harvey | Vaccinating devices |
US3221739A (en) * | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3221740A (en) * | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3556080A (en) * | 1968-04-08 | 1971-01-19 | Lincoln Lab Inc | Skin allergy testing device |
US3596660A (en) * | 1969-05-12 | 1971-08-03 | Illinois Tool Works | Injection device |
US3675766A (en) * | 1970-02-04 | 1972-07-11 | Sol Roy Rosenthal | Multiple puncture injector device |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
FR2232331B1 (de) * | 1973-06-06 | 1978-03-24 | Guerin A Ets | |
OA05448A (fr) * | 1975-10-16 | 1981-03-31 | Manufrance Manufacture Francai | Dispositif vaccinateur multipénétrant. |
US4159659A (en) * | 1978-05-16 | 1979-07-03 | Carol Nightingale | Electrical marking device |
US4222392A (en) * | 1979-05-23 | 1980-09-16 | Alier-Screen, Inc. | Allergy testing device with vented base |
US4320758A (en) * | 1979-05-07 | 1982-03-23 | Alza Corporation | Osmotically driven fluid dispenser |
CA1247960A (en) * | 1983-03-24 | 1989-01-03 | Hideki Aoki | Transcutaneously implantable element |
US5865786A (en) * | 1983-08-18 | 1999-02-02 | Drug Delivery Systems, Inc. | Programmable control and mounting system for transdermal drug applicator |
US4921475A (en) * | 1983-08-18 | 1990-05-01 | Drug Delivery Systems Inc. | Transdermal drug patch with microtubes |
US4664651A (en) * | 1985-03-01 | 1987-05-12 | The Procter & Gamble Company | Subatmospheric method and apparatus for expanding blood vessels to facilitate puncture with a cannula |
US4671288A (en) * | 1985-06-13 | 1987-06-09 | The Regents Of The University Of California | Electrochemical cell sensor for continuous short-term use in tissues and blood |
US4775361A (en) * | 1986-04-10 | 1988-10-04 | The General Hospital Corporation | Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport |
US5335670A (en) * | 1986-04-18 | 1994-08-09 | Henry Fishman | Allergy testing method and apparatus |
US4969468A (en) * | 1986-06-17 | 1990-11-13 | Alfred E. Mann Foundation For Scientific Research | Electrode array for use in connection with a living body and method of manufacture |
US4703761A (en) * | 1986-08-04 | 1987-11-03 | Rathbone R Rodion | Blood sampling device for obtaining small quantity of venous blood |
US4771660A (en) * | 1987-08-24 | 1988-09-20 | Harold Yacowitz | Needle holder |
US4798582A (en) * | 1987-10-27 | 1989-01-17 | Permark Corp. C/O Sci/Med Advances Corp. | Needle cartridge |
US5147355A (en) * | 1988-09-23 | 1992-09-15 | Brigham And Womens Hospital | Cryoablation catheter and method of performing cryoablation |
EP0429842B1 (de) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten |
US5697901A (en) * | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
US5054339A (en) * | 1990-02-20 | 1991-10-08 | Harold Yacowitz | Tattooing assembly |
US5858188A (en) * | 1990-02-28 | 1999-01-12 | Aclara Biosciences, Inc. | Acrylic microchannels and their use in electrophoretic applications |
US5138220A (en) * | 1990-12-05 | 1992-08-11 | Science Applications International Corporation | Field emission cathode of bio-molecular or semiconductor-metal eutectic composite microstructures |
US5527288A (en) * | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
US5279544A (en) | 1990-12-13 | 1994-01-18 | Sil Medics Ltd. | Transdermal or interdermal drug delivery devices |
TW279133B (de) * | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5312456A (en) | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
US5632957A (en) * | 1993-11-01 | 1997-05-27 | Nanogen | Molecular biological diagnostic systems including electrodes |
US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
WO1993020784A1 (en) * | 1992-04-10 | 1993-10-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | A microneedle for injection of ocular blood vessels |
US5279552A (en) * | 1993-01-11 | 1994-01-18 | Anton Magnet | Intradermal injection device |
US5383512A (en) * | 1993-01-27 | 1995-01-24 | Midwest Research Institute | Method for fabricating a substrate having spaced apart microcapillaries thereon |
US5401242A (en) * | 1993-02-25 | 1995-03-28 | Yacowitz; Harold | Apparatus for injecting a substance into the skin |
US5582184A (en) * | 1993-10-13 | 1996-12-10 | Integ Incorporated | Interstitial fluid collection and constituent measurement |
US5618295A (en) * | 1993-10-16 | 1997-04-08 | Samsung Electro-Mechanics Co., Ltd. | Apparatus for preparing skin in advance |
EP0892444B1 (de) | 1993-11-02 | 2004-04-21 | Matsushita Electric Industrial Co., Ltd | Halbleiterbauelement mit einem Aggregat von Mikro-Nadeln aus Halbleitermaterial |
JP3590805B2 (ja) | 1993-11-10 | 2004-11-17 | 株式会社ニコン | 採血装置 |
US5885211A (en) * | 1993-11-15 | 1999-03-23 | Spectrix, Inc. | Microporation of human skin for monitoring the concentration of an analyte |
WO1997007734A1 (en) | 1995-08-29 | 1997-03-06 | Spectrx, Inc. | Microporation of human skin for drug delivery and monitoring applications |
JPH07196314A (ja) | 1993-12-28 | 1995-08-01 | Maruo Calcium Co Ltd | チューブ状合成無機微粒子 |
ATE231733T1 (de) * | 1994-01-21 | 2003-02-15 | Powderject Vaccines Inc | Gasbetätigtes element zum austragen von genmaterial |
US5457041A (en) * | 1994-03-25 | 1995-10-10 | Science Applications International Corporation | Needle array and method of introducing biological substances into living cells using the needle array |
US5899880A (en) * | 1994-04-08 | 1999-05-04 | Powderject Research Limited | Needleless syringe using supersonic gas flow for particle delivery |
US5611806A (en) * | 1994-05-23 | 1997-03-18 | Samsung Electro-Mechanics Co., Ltd. | Skin perforating device for transdermal medication |
KR0134152B1 (ko) * | 1994-05-23 | 1998-04-14 | 이형도 | 의약품 투여용 피부흠집 형성장치 |
US5591139A (en) * | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
GB9422260D0 (en) * | 1994-11-04 | 1994-12-21 | Owen Mumford Ltd | Improvements relating to skin prickers |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US5599302A (en) * | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
US5611942A (en) * | 1995-03-02 | 1997-03-18 | Kabushiki Kaisha Toshiba | Method for producing tips for atomic force microscopes |
WO1996037256A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
AU5740496A (en) * | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
AU6104896A (en) | 1995-06-07 | 1996-12-30 | Regents Of The University Of California, The | Therapeutic microdevices and methods of making and using sam e |
US5983130A (en) | 1995-06-07 | 1999-11-09 | Alza Corporation | Electrotransport agent delivery method and apparatus |
DE19525607A1 (de) * | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneales Arzneimittelfreigabesystem |
US5658515A (en) * | 1995-09-25 | 1997-08-19 | Lee; Abraham P. | Polymer micromold and fabrication process |
US5758505C1 (en) * | 1995-10-12 | 2001-10-30 | Cryogen Inc | Precooling system for joule-thomson probe |
US5883211A (en) * | 1996-01-19 | 1999-03-16 | Aclara Biosciences, Inc. | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis |
US5801057A (en) * | 1996-03-22 | 1998-09-01 | Smart; Wilson H. | Microsampling device and method of construction |
EP0925088A2 (de) | 1996-06-28 | 1999-06-30 | Sontra Medical, L.P. | Ultraschallsteigerung des transdermalen transports |
US6183434B1 (en) | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
US5699157A (en) * | 1996-07-16 | 1997-12-16 | Caliper Technologies Corp. | Fourier detection of species migrating in a microchannel |
US5911223A (en) * | 1996-08-09 | 1999-06-15 | Massachusetts Institute Of Technology | Introduction of modifying agents into skin by electroporation |
EP0957972B1 (de) | 1996-12-20 | 2003-03-19 | Alza Corporation | Vorrichtung und verfahren zur erhöhung des transdermalen wirkstoffeflusses |
US5876675A (en) * | 1997-08-05 | 1999-03-02 | Caliper Technologies Corp. | Microfluidic devices and systems |
DE69806963T2 (de) * | 1997-12-11 | 2002-11-21 | Alza Corp., Mountain View | Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
WO2000048669A1 (en) | 1999-02-18 | 2000-08-24 | Biovalve Technologies, Inc. | Electroactive pore |
AU5461300A (en) | 1999-06-04 | 2000-12-28 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
DE60027720T2 (de) * | 1999-06-08 | 2007-04-26 | Altea Therapeutics Corp. | Vorrichtung zur mikroporation eines biologischen gewebes mittels einer filmgewebe schnittstellenvorrichtung und verfahren |
US6312612B1 (en) * | 1999-06-09 | 2001-11-06 | The Procter & Gamble Company | Apparatus and method for manufacturing an intracutaneous microneedle array |
AU2736501A (en) * | 1999-12-30 | 2001-07-16 | Redeon, Inc. | Stacked microneedle systems |
US6558361B1 (en) * | 2000-03-09 | 2003-05-06 | Nanopass Ltd. | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems |
US6565532B1 (en) * | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
WO2001091846A2 (en) * | 2000-05-26 | 2001-12-06 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
EP2554196B1 (de) * | 2000-11-30 | 2018-10-17 | Valeritas, Inc. | Flüssigkeitsabgabe- und -messsysteme |
-
2002
- 2002-09-23 WO PCT/US2002/030117 patent/WO2003024508A2/en not_active Application Discontinuation
- 2002-09-23 AU AU2002330083A patent/AU2002330083A1/en not_active Abandoned
- 2002-09-23 US US10/252,739 patent/US8920375B2/en not_active Expired - Fee Related
- 2002-09-23 DE DE60239229T patent/DE60239229D1/de not_active Expired - Lifetime
- 2002-09-23 CA CA2499838A patent/CA2499838C/en not_active Expired - Fee Related
- 2002-09-23 EP EP02766341A patent/EP1471953B1/de not_active Expired - Lifetime
- 2002-09-23 AT AT02766341T patent/ATE498418T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US8920375B2 (en) | 2014-12-30 |
EP1471953B1 (de) | 2011-02-16 |
US20030135158A1 (en) | 2003-07-17 |
AU2002330083A1 (en) | 2003-04-01 |
CA2499838A1 (en) | 2003-03-27 |
DE60239229D1 (de) | 2011-03-31 |
WO2003024508A3 (en) | 2003-12-24 |
EP1471953A2 (de) | 2004-11-03 |
WO2003024508A2 (en) | 2003-03-27 |
WO2003024508A9 (en) | 2004-03-25 |
CA2499838C (en) | 2012-12-18 |
EP1471953A4 (de) | 2007-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE498418T1 (de) | Durch gasdruck betätigte mikronadel-anordnungen und damit zusammenhängende systeme und verfahren | |
WO2003024507A3 (en) | Microneedles, microneedle arrays, and systems and methods relating to same | |
NO20035645L (no) | Forsterket medikamentlevering i transdermale systemer | |
MY151020A (en) | Transdermal therapeutic system | |
WO2005020912A3 (en) | Delivery of immune response modifier compounds | |
UA99431C2 (uk) | Спосіб збирання пристрою для доставки ліків та пристрій для доставки ліків | |
WO2006015299A3 (en) | Multi-reservoir device for transdermal drug delivery and sensing | |
WO2006083681A3 (en) | Coated microprojections having reduced variability and method for producing same | |
DK3326673T3 (da) | Sprøjter, sprøjtegrænseflader og sprøjtestempler til anvendelse med medicinske injektorer | |
ZA200200808B (en) | Needleless hypodermic injection system, application device and medication cartridge therefor. | |
UA87334C2 (ru) | Приводной механизм для применения в устройстве введения лекарств, устройство введения лекарств, применение приводного механизма (варианты) и способ сборки устройства введения лекарств | |
WO2008078318A3 (en) | Systems and devices for sustained delivery of therapeutic fluid | |
WO2003026733A3 (en) | Microneedle with membrane | |
NO20053297D0 (no) | Inhaleringsinnretning for transpulmonaer administrering. | |
EA200601129A1 (ru) | Способ лечения нежелательного эффекта при чрескожной доставке лекарства (варианты) | |
DK1841863T3 (da) | Fremgangsmåde til rensning af faktor VII | |
EP1450876A4 (de) | Integriertes transdermales arzneimittelabgabesystem | |
AR046608A1 (es) | Aparato para la administracion transdermica de agentes a base de nicotina | |
WO2008039319A3 (en) | Injection of therapeutic into porous regions of a medical device | |
ATE471146T1 (de) | Transdermale verabreichungssysteme | |
ATE491485T1 (de) | Implantierbares arzneiabgabegerät | |
DE602005004782D1 (de) | Transdermale arzneimittelabgabevorrichtung durch dehnung/lockerung | |
WO2001066065A3 (en) | Systems and methods for fluid transport through dermal barriers | |
AU2003212962A8 (en) | Transdermal drug delivery systems | |
DE60216458D1 (de) | Verfahren zum auslösen einer anhaltenden immunreaktion |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |