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ATE492528T1 - Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung - Google Patents

Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung

Info

Publication number
ATE492528T1
ATE492528T1 AT02806661T AT02806661T ATE492528T1 AT E492528 T1 ATE492528 T1 AT E492528T1 AT 02806661 T AT02806661 T AT 02806661T AT 02806661 T AT02806661 T AT 02806661T AT E492528 T1 ATE492528 T1 AT E492528T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
derivatives
hydroxyalkyltetramethyl
antiepileptic
production
Prior art date
Application number
AT02806661T
Other languages
English (en)
Inventor
Meir Bialer
Nina Isoherranen
Yagen Boris
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE492528T1 publication Critical patent/ATE492528T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02806661T 2002-02-01 2002-12-29 Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung ATE492528T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL147953A IL147953A (en) 2002-02-01 2002-02-01 Derivatives and pharmaceutical compositions of n-hydroxymethyl tetramethylcyclopropyl-
PCT/IL2002/001050 WO2003064374A1 (en) 2002-02-01 2002-12-29 Derivatives and pharmaceutical compositions of n-hydroxyalkyl tetramethylcyclopropane-carboxamide, having anti-epileptic, neurological, and cns activity, and method for their preparation

Publications (1)

Publication Number Publication Date
ATE492528T1 true ATE492528T1 (de) 2011-01-15

Family

ID=27638031

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02806661T ATE492528T1 (de) 2002-02-01 2002-12-29 Derivate und pharmazeutische zusammensetzungen von n-hydroxyalkyltetramethyl cyclo propan carboxamid mit antiepileptischer und verfahren zu deren herstellung

Country Status (6)

Country Link
US (1) US6960687B2 (de)
EP (1) EP1487787B1 (de)
AT (1) ATE492528T1 (de)
DE (1) DE60238717D1 (de)
IL (1) IL147953A (de)
WO (1) WO2003064374A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL157751A0 (en) 2003-02-28 2004-03-28 Yissum Res Dev Co New amide derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid, a method for their synthesis and pharmaceutical compositions containing them
IL156203A0 (en) * 2003-05-29 2003-12-23 Yissum Res Dev Co Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders
FR2856595B1 (fr) * 2003-06-27 2008-05-30 Exonhit Therapeutics Sa Methodes et compositions pour le traitement de deficits cognitifs.
US20060004098A1 (en) 2003-07-28 2006-01-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compounds useful for treating neurological disorders
JP4954864B2 (ja) 2004-04-01 2012-06-20 カーディオム ファーマ コーポレイション イオンチャネル調節化合物のプロドラッグおよびその使用
EP2114864A1 (de) * 2007-02-21 2009-11-11 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd Alpha-halogen- und alpha-alkylcyclopropylcarboxylverbindungen und anwendungen davon

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA74202B (en) 1973-01-11 1974-11-27 Hexachimie New amine derivatives of 2,2-diaryl cyclopropanes
SE9303274D0 (sv) 1993-10-07 1993-10-07 Astra Ab Novel phenylethyl and phenylproplamines
IL108595A (en) * 1994-02-08 1998-09-24 Yissum Res Dev Co History of Carboxylic Acid 2,2,3,3 Tetramethyl Cyclophen (ACMT) (Process for their Preparation and Pharmaceutical Preparations Containing Them)
IL120006A (en) * 1997-01-14 2000-12-06 Yissum Res Dev Co Valnoctamide stereoisomers and a method for their synthesis and separation
WO1998030538A1 (fr) 1997-01-14 1998-07-16 Kaneka Corporation Procede servant a preparer des derives de cysteine
US6090854A (en) 1998-03-20 2000-07-18 Bristol-Meyers Company Aryloxyanilides and related compounds
IL124118A (en) * 1998-04-16 2007-09-20 Yissum Res Dev Co Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, method for their synthesis and pharmaceutical compositions containing them
UA74852C2 (en) * 2000-12-08 2006-02-15 3M Innovative Properties Co Urea-substituted imidazoquinoline ethers
US6610326B2 (en) * 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets

Also Published As

Publication number Publication date
DE60238717D1 (de) 2011-02-03
WO2003064374A1 (en) 2003-08-07
EP1487787B1 (de) 2010-12-22
IL147953A0 (en) 2003-07-31
IL147953A (en) 2008-04-13
US20050131069A1 (en) 2005-06-16
US6960687B2 (en) 2005-11-01
EP1487787A1 (de) 2004-12-22

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