[go: up one dir, main page]

ATE488516T1 - 14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung - Google Patents

14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung

Info

Publication number
ATE488516T1
ATE488516T1 AT05757149T AT05757149T ATE488516T1 AT E488516 T1 ATE488516 T1 AT E488516T1 AT 05757149 T AT05757149 T AT 05757149T AT 05757149 T AT05757149 T AT 05757149T AT E488516 T1 ATE488516 T1 AT E488516T1
Authority
AT
Austria
Prior art keywords
sub
formula
radical
alkyl radicals
group
Prior art date
Application number
AT05757149T
Other languages
English (en)
Inventor
Paola Ciapetti
Laurence Deyon
Camille-Georges Wermuth
Jean-Francois Pujol
Dinah Weissmann
Original Assignee
Biocortech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocortech filed Critical Biocortech
Application granted granted Critical
Publication of ATE488516T1 publication Critical patent/ATE488516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Steroid Compounds (AREA)
AT05757149T 2004-04-14 2005-04-14 14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung ATE488516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0403873A FR2869034B1 (fr) 2004-04-14 2004-04-14 Derive du 14,15-dihydro 20,21-dinoreburnamenin 14-ol et leur utilisation pour le traitement des depressions
PCT/FR2005/000902 WO2005103047A1 (fr) 2004-04-14 2005-04-14 Derives du 14.15-dihydro 20.21-dinoreburnamenin-14-ol, et leurs applications

Publications (1)

Publication Number Publication Date
ATE488516T1 true ATE488516T1 (de) 2010-12-15

Family

ID=34944654

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05757149T ATE488516T1 (de) 2004-04-14 2005-04-14 14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung

Country Status (12)

Country Link
US (1) US7354918B2 (de)
EP (1) EP1737856B1 (de)
JP (1) JP5156371B2 (de)
CN (1) CN1953977B (de)
AT (1) ATE488516T1 (de)
CA (1) CA2563491A1 (de)
DE (1) DE602005024788D1 (de)
ES (1) ES2356657T3 (de)
FR (1) FR2869034B1 (de)
HK (1) HK1106502A1 (de)
IL (1) IL178548A (de)
WO (1) WO2005103047A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4112053B1 (de) * 2016-10-11 2024-02-14 Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE) Behandlung von synukleinopathien

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081587B1 (de) 1970-03-26 1973-04-06 Anvar
BE797328R (en) * 1971-08-31 1973-07-16 Omnium Chimique Sa Aminopropyl vincanols and eburnamines prepn - - by reaction of organo magnesium cpd with a vincanone or substd ebur
FR2190113A5 (de) 1972-06-19 1974-01-25 Anvar
DE2538095A1 (de) * 1974-09-06 1976-03-25 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
CH605949A5 (en) * 1974-09-06 1978-10-13 Sandoz Ag Vincanol derivs
FI751840A (de) 1974-09-24 1976-03-25 Synthelabo
FR2312245A1 (fr) * 1975-05-26 1976-12-24 Synthelabo Nouveaux apovincamides, leurs sels, leur preparation et les medicaments qui en contiennent
HU171163B (hu) * 1974-09-27 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh trans eburnamenina
CH612968A5 (en) * 1975-06-03 1979-08-31 Sandoz Ag Process for the preparation of novel compounds from the vincanol-epivincanol group
FR2381048A1 (fr) 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
FR2433528A2 (fr) 1978-08-16 1980-03-14 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
FR2623503B1 (de) * 1987-11-19 1991-04-05 Roussel Uclaf
FR2623501B1 (fr) 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
EP1737856B1 (de) 2010-11-17
JP5156371B2 (ja) 2013-03-06
WO2005103047A1 (fr) 2005-11-03
JP2007532612A (ja) 2007-11-15
US20070088046A1 (en) 2007-04-19
ES2356657T3 (es) 2011-04-12
FR2869034A1 (fr) 2005-10-21
IL178548A (en) 2010-12-30
CN1953977B (zh) 2011-06-01
DE602005024788D1 (de) 2010-12-30
US7354918B2 (en) 2008-04-08
WO2005103047A8 (fr) 2006-11-16
CN1953977A (zh) 2007-04-25
CA2563491A1 (fr) 2005-11-03
EP1737856A1 (de) 2007-01-03
HK1106502A1 (de) 2008-03-14
FR2869034B1 (fr) 2008-04-04
IL178548A0 (en) 2007-02-11

Similar Documents

Publication Publication Date Title
DK2314582T3 (da) Heterocykliske forbindelser som antivirusmidler
EA200500018A1 (ru) Бензконденсированные гетероариламидные производные тиенопиридинов, применяемые в качестве терапевтических агентов, фармацевтические композиции, включающие их, и способы их применения
MEP36508A (en) Triazolopyrazine derivatives useful as anti-cancer agents
DK1487444T3 (da) Anvendelse af pyridylamider som angiogeneseinhibitorer
CY1106522T1 (el) Ετepοκυκλικη ενωση και αντικαρκινικο μεσο που πepιεχει την ιδια ως δραστικο συστατικο
PE20080827A1 (es) N-(1-hetaril-piperidin-4-il)-(het) arilamidas como moduladores del receptor ep2
HRP20050191B1 (hr) Novi derivati benzoimidazola korisni kao antiproliferativna sredstva
AR047076A1 (es) Compuestos de pirrolotriazina como inhibidores de tirosina quinasas, composiciones farmaceuticas
AR052887A1 (es) Derivados de tiazol, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para tratar enfermedades mediadas por la inhibicion de la protein quinasa
HRP20031098B1 (en) Beta-amino tetrahydroimidazo (1,2-a) pyrazines and tetrahydrotrioazolo (4,3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
AR056886A1 (es) Compuestos de pirrolopiridina sustituida inhibidores de quinasas, composiciones farmaceuticas que los contienen y usos en el tratamiento del cancer
AR049551A1 (es) Derivados de amino-5, 5-difenilimidazolona para la inhibicion de la beta-secretasa
DK1697371T3 (da) Azabicykliske heterocykliske forbindelser som cannabinoidreceptormodulatorer
RS51550B (en) KAO DERIVATIVES KAO MODULATORS CCR5
AR043485A1 (es) Derivados del 8'-piridinil-dihidrospiro-[cicloalquil]-pirimido[1,2a]pirimidin-6-ona y 8´-pirimidinil-dihidrospiro-[cicloalquil]-pirimido[1,2a]pirimidin-6-ona substituidos
EA201070018A1 (ru) Замещенные 2-[2-(фенил)этиламино] алканамидные производные и применение указанных соединений в качестве модуляторов натриевых и/или кальциевых каналов
ATE476431T1 (de) Piperidin- und azetidinderivate als glyt1- inhibitoren
AR049276A1 (es) Compuestos carboxamidos opiodes y composiciones farmaceuticas que los contienen
CY1108837T1 (el) ΝΕΑ ΠΑΡΑΓΩΓΑ ΑΜΙΝΟΠΥΡΙΔΙΝΗΣ ΩΣ ΑΝΤΑΓΩΝΙΣΤΕΣ mGluR5
AR054220A1 (es) 5-fenilpirimidinas i sustituidas, composicion farmaceutica y uso del compuesto para la fabricacion de un medicamento
ATE488516T1 (de) 14,15-dihydro-20,21-dinoreburnamenin-14-ol- derivate und deren anwendung
AR024219A1 (es) COMPUESTOS DE QUINOLONAS 2-(NH- U O-SUSTITUIDAS) UTILES COMO INHIBIDORES DE LA METIONIL t-RNA SINTETASA (MRS) COMPOSICIONES FARMACEUTICAS FORMULADAS CONDICHOS COMPUESTOS; PROCEDIMIENTO PARA SU PREPARACION Y USO DE DICHOS COMPUESTOS PARA PREPARAR MEDICAMENTOS PARA EL TRATAMIENTO DE INFECCIONES BACTER
PE20070102A1 (es) Amidas sustituidas con heteroarilo que comprenden un grupo enlazador saturado como moduladores de la oxido nitrico sintasa
AR043507A1 (es) Derivados de anilina sustituidos y composiciones farmaceuticas
ATE229934T1 (de) Sulfonamid-derivate

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties