ATE487692T1 - Verfahren und verbindungen zum nachweis von medizinischen erkrankungen - Google Patents
Verfahren und verbindungen zum nachweis von medizinischen erkrankungenInfo
- Publication number
- ATE487692T1 ATE487692T1 AT05758946T AT05758946T ATE487692T1 AT E487692 T1 ATE487692 T1 AT E487692T1 AT 05758946 T AT05758946 T AT 05758946T AT 05758946 T AT05758946 T AT 05758946T AT E487692 T1 ATE487692 T1 AT E487692T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- methods
- medical diseases
- detecting medical
- provides methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000007850 degeneration Effects 0.000 abstract 2
- 230000030833 cell death Effects 0.000 abstract 1
- 230000008809 cell oxidative stress Effects 0.000 abstract 1
- 230000034994 death Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000036542 oxidative stress Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
- C07C323/49—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
- C07C323/02—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/03—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physiology (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Neurology (AREA)
- Optics & Photonics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Electrotherapy Devices (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58585204P | 2004-07-08 | 2004-07-08 | |
| PCT/IL2005/000725 WO2006006156A2 (en) | 2004-07-08 | 2005-07-07 | Compounds/methods for detection of medical disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE487692T1 true ATE487692T1 (de) | 2010-11-15 |
Family
ID=35784250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05758946T ATE487692T1 (de) | 2004-07-08 | 2005-07-07 | Verfahren und verbindungen zum nachweis von medizinischen erkrankungen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8101666B2 (de) |
| EP (1) | EP1773762B1 (de) |
| JP (1) | JP2008505884A (de) |
| AT (1) | ATE487692T1 (de) |
| DE (1) | DE602005024690D1 (de) |
| WO (1) | WO2006006156A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5322527B2 (ja) * | 2008-07-17 | 2013-10-23 | 浜松ホトニクス株式会社 | アポトーシスの検出に適した化合物 |
| WO2017017669A1 (en) * | 2015-07-24 | 2017-02-02 | Aposense Ltd. | Pro-drugs and related methods |
| JP7348064B2 (ja) * | 2017-01-09 | 2023-09-20 | アポセンス リミテッド | 分子を経膜送達するための化合物及び方法 |
| US12337036B2 (en) | 2018-01-01 | 2025-06-24 | Aposense Ltd | Compounds and methods for trans-membrane delivery of molecules |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3133303A1 (de) * | 1981-08-22 | 1983-03-03 | Chemische Fabrik Pfersee Gmbh, 8900 Augsburg | Verfahren zur herstellung von perfluoralkylreste enthaltenden kondensationsprodukten, die so hergestellten kondensationsprodukte und deren verwendung |
| US4677241A (en) | 1986-08-15 | 1987-06-30 | Chevron Research Company | Olefin oligomerization process and catalyst |
| US6322446B1 (en) * | 1999-12-10 | 2001-11-27 | Elot, Inc. | System and a method for operating on-line state lottery games |
| JP4234430B2 (ja) * | 2001-01-17 | 2009-03-04 | エムジーアイ ジーピー インコーポレイティッド | チオールを含むｎａａｌａｄアーゼ抑制物質 |
| US7605182B2 (en) | 2003-05-01 | 2009-10-20 | Aposense Ltd. | Compounds that selectively bind to membranes of apoptotic cells |
| GB0327494D0 (en) * | 2003-11-26 | 2003-12-31 | Amersham Plc | Novel imaging agents |
-
2005
- 2005-07-07 EP EP05758946A patent/EP1773762B1/de not_active Expired - Lifetime
- 2005-07-07 US US11/631,490 patent/US8101666B2/en not_active Expired - Fee Related
- 2005-07-07 JP JP2007519981A patent/JP2008505884A/ja not_active Withdrawn
- 2005-07-07 DE DE602005024690T patent/DE602005024690D1/de not_active Expired - Lifetime
- 2005-07-07 WO PCT/IL2005/000725 patent/WO2006006156A2/en active Application Filing
- 2005-07-07 AT AT05758946T patent/ATE487692T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1773762B1 (de) | 2010-11-10 |
| US20070232702A1 (en) | 2007-10-04 |
| WO2006006156A3 (en) | 2006-12-07 |
| JP2008505884A (ja) | 2008-02-28 |
| WO2006006156A2 (en) | 2006-01-19 |
| EP1773762A4 (de) | 2008-12-10 |
| EP1773762A2 (de) | 2007-04-18 |
| DE602005024690D1 (de) | 2010-12-23 |
| US8101666B2 (en) | 2012-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |