ATE465750T1 - Verwendung eines replikationdefizienten pockenvirusvektors zur erhöhung der cd4+ t-zell- immunantwort gegen antigen - Google Patents
Verwendung eines replikationdefizienten pockenvirusvektors zur erhöhung der cd4+ t-zell- immunantwort gegen antigenInfo
- Publication number
- ATE465750T1 ATE465750T1 AT01965468T AT01965468T ATE465750T1 AT E465750 T1 ATE465750 T1 AT E465750T1 AT 01965468 T AT01965468 T AT 01965468T AT 01965468 T AT01965468 T AT 01965468T AT E465750 T1 ATE465750 T1 AT E465750T1
- Authority
- AT
- Austria
- Prior art keywords
- replication
- antigen
- deficiency
- increase
- immune response
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0023203.3A GB0023203D0 (en) | 2000-09-21 | 2000-09-21 | Vaccination method |
| PCT/GB2001/004116 WO2002024224A2 (en) | 2000-09-21 | 2001-09-13 | Use of replication-deficient poxvirus vector to boost cd4+ t cell immune response to antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE465750T1 true ATE465750T1 (de) | 2010-05-15 |
Family
ID=9899889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01965468T ATE465750T1 (de) | 2000-09-21 | 2001-09-13 | Verwendung eines replikationdefizienten pockenvirusvektors zur erhöhung der cd4+ t-zell- immunantwort gegen antigen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20040018177A1 (de) |
| EP (1) | EP1320379B8 (de) |
| JP (1) | JP5102930B2 (de) |
| AT (1) | ATE465750T1 (de) |
| AU (2) | AU8610901A (de) |
| CA (1) | CA2422094C (de) |
| DE (1) | DE60141969D1 (de) |
| ES (1) | ES2345604T3 (de) |
| GB (2) | GB0023203D0 (de) |
| WO (1) | WO2002024224A2 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030138454A1 (en) * | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| US7445924B2 (en) | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| US7628980B2 (en) | 2000-11-23 | 2009-12-08 | Bavarian Nordic A/S | Modified vaccinia virus ankara for the vaccination of neonates |
| KR20090057335A (ko) | 2000-11-23 | 2009-06-04 | 버베리안 노딕 에이/에스 | 변형된 백시니아 앙카라 바이러스 변형체 |
| GB0118532D0 (en) * | 2001-07-30 | 2001-09-19 | Isis Innovation | Materials and methods relating to improved vaccination strategies |
| AU2002347317B2 (en) * | 2001-11-30 | 2008-06-26 | Isis Innovation Limited | Vaccine |
| DE60314823T3 (de) * | 2002-04-19 | 2017-11-16 | Bavarian Nordic A/S | Modifizierte variante des vaccinia ankara virus als impfstoff für neugeborene |
| JP4654026B2 (ja) * | 2002-05-20 | 2011-03-16 | 独立行政法人科学技術振興機構 | Ｂｃｇワクチンとその利用 |
| NZ538575A (en) | 2002-09-05 | 2007-03-30 | Bavarian Nordic As | Method for the amplification of a virus wherein primary avian cells are cultivated in a serum-free medium comprising growth factors and attachment factors |
| DE10249390A1 (de) * | 2002-10-23 | 2004-05-13 | Ruprecht-Karls-Universität Heidelberg | Rekombinante MVA-Stämme als potentielle Impfstoffe gegen P.falciparum-Malaria |
| US20050175627A1 (en) * | 2003-09-24 | 2005-08-11 | Oxxon Therapeutics Ltd. | HIV pharmaccines |
| GB2421025A (en) * | 2004-12-09 | 2006-06-14 | Oxxon Therapeutics Ltd | HSV vaccination vectors |
| EP1890724A2 (de) * | 2005-05-13 | 2008-02-27 | Oxxon Therapeutics Limited | Zusammensetzungen zur auslösung einer immunantwort |
| EP2125868B1 (de) * | 2007-02-28 | 2015-06-10 | The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services | Brachyurie-polypeptide und verwendungsverfahren |
| JP2017527564A (ja) | 2014-09-03 | 2017-09-21 | バヴァリアン ノルディック エー／エス | 免疫応答の増進を目的とする方法及び組成物 |
| FI3656395T3 (fi) | 2014-09-03 | 2024-02-05 | Bavarian Nordic As | Menetelmiä ja koostumuksia suojaavan immuniteetin aikaansaamiseksi filovirusinfektiota vastaan |
| ES2865150T3 (es) | 2014-09-26 | 2021-10-15 | Beth Israel Deaconess Medical Ct Inc | Métodos y composiciones para inducir inmunidad protectora contra la infección por el virus de la inmunodeficiencia humana |
| CN105753989A (zh) * | 2014-12-15 | 2016-07-13 | 牛津疫苗医学生物科技（英国）有限公司 | 人工多抗原融合蛋白及其制备和应用 |
| ES2921605T3 (es) | 2016-01-29 | 2022-08-30 | Bavarian Nordic As | Vacuna contra el virus de la encefalitis equina basada en el virus de la variolovacuna modificado Ankara (VMA) recombinante |
| MX2018012376A (es) | 2016-04-13 | 2019-08-01 | Synthetic Genomics Inc | Sistemas de replicón de arterivirus recombinantes y usos de estos. |
| EP3484507A1 (de) | 2016-07-15 | 2019-05-22 | Janssen Vaccines & Prevention B.V. | Verfahren und zusammensetzungen zur induzierung von schützender immunität gegen eine marburg-virus-infektion |
| CN110494159A (zh) | 2016-09-02 | 2019-11-22 | 扬森疫苗与预防公司 | 在接受抗逆转录病毒治疗的对象中诱导针对人类免疫缺陷病毒感染的免疫应答的方法 |
| US11364310B2 (en) | 2016-10-17 | 2022-06-21 | Janssen Pharmaceuticals, Inc. | Recombinant virus replicon systems and uses thereof |
| JP2020500536A (ja) | 2016-12-05 | 2020-01-16 | シンセティック ジェノミクス インコーポレーテッド | 遺伝子発現増強のための組成物および方法 |
| EP3606553A1 (de) | 2017-04-06 | 2020-02-12 | Janssen Vaccines & Prevention B.V. | Mva-bn- und ad26.zebov- oder ad26.filo-prime-boost-schema |
| US20190022212A1 (en) | 2017-07-21 | 2019-01-24 | Beth Israel Deaconess Medical Center, Inc. | Methods for safe induction of cross-clade immunity against human immunodeficiency virus infection in human |
| WO2019055888A1 (en) | 2017-09-18 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHODS OF INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN SUBJECTS UNDER ANTIRETROVIRAL TREATMENT |
| EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
| US11021692B2 (en) | 2017-12-19 | 2021-06-01 | Janssen Sciences Ireland Unlimited Company | Hepatitis B virus (HBV) vaccines and uses thereof |
| MX2020006471A (es) | 2017-12-19 | 2020-09-22 | Janssen Sciences Ireland Unlimited Co | Metodos y composiciones para inducir una respuesta inmune contra el virus de hepatitis b (hbv). |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| US11083786B2 (en) | 2018-01-19 | 2021-08-10 | Janssen Pharmaceuticals, Inc. | Induce and enhance immune responses using recombinant replicon systems |
| WO2020237052A1 (en) | 2019-05-22 | 2020-11-26 | Janssen Vaccines & Prevention B.V. | Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment |
| EP3928789A1 (de) | 2020-06-24 | 2021-12-29 | Consejo Superior de Investigaciones Científicas (CSIC) | Mva-basierter impfstoff gegen covid-19 exprimierende sars-cov-2-antigene |
| WO2021260065A1 (en) | 2020-06-24 | 2021-12-30 | Consejo Superior De Investigaciones Científicas (Csic) | Mva-based vaccine against covid-19 expressing sars-cov-2 antigens |
| PH12023550030A1 (en) | 2020-07-08 | 2024-03-11 | Janssen Sciences Ireland Unlimited Co | Rna replicon vaccines against hbv |
| EP4358999A1 (de) | 2021-06-23 | 2024-05-01 | Consejo Superior De Investigaciones Científicas | Mva-basierter impfstoff zur expression eines präfusionsstabilisierten sars-cov-2s-proteins |
| EP4108257A1 (de) | 2021-06-23 | 2022-12-28 | Consejo Superior De Investigaciones Científicas | Impfstoff auf mva-basis gegen covid-19, der ein präfusionsstabilisiertes sars-cov-2-s-protein exprimiert |
| WO2023198815A1 (en) | 2022-04-14 | 2023-10-19 | Janssen Vaccines & Prevention B.V. | Sequential administration of adenoviruses |
| EP4316514A1 (de) | 2022-08-03 | 2024-02-07 | Consejo Superior de Investigaciones Científicas (CSIC) | Vektoren auf mva-basis und ihre verwendung als impfstoff gegen sars-cov-2 |
| WO2024063788A1 (en) * | 2022-09-23 | 2024-03-28 | BioNTech SE | Compositions for delivery of malaria antigens and related methods |
| WO2024064931A1 (en) * | 2022-09-23 | 2024-03-28 | BioNTech SE | Compositions for delivery of liver stage antigens and related methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| WO2001082964A1 (en) * | 2000-04-28 | 2001-11-08 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Improved immunogenicity using a combination of dna and vaccinia virus vector vaccines |
| PT1282702E (pt) * | 2000-05-10 | 2007-02-28 | Ludwig Inst Cancer Res | Polipéptidos imunogénicos codificados por minigenes mage e suas utilizações |
-
2000
- 2000-09-21 GB GBGB0023203.3A patent/GB0023203D0/en not_active Ceased
-
2001
- 2001-09-13 EP EP01965468A patent/EP1320379B8/de not_active Expired - Lifetime
- 2001-09-13 CA CA2422094A patent/CA2422094C/en not_active Expired - Lifetime
- 2001-09-13 ES ES01965468T patent/ES2345604T3/es not_active Expired - Lifetime
- 2001-09-13 AU AU8610901A patent/AU8610901A/xx active Pending
- 2001-09-13 DE DE60141969T patent/DE60141969D1/de not_active Expired - Lifetime
- 2001-09-13 AU AU2001286109A patent/AU2001286109B2/en not_active Expired
- 2001-09-13 JP JP2002528294A patent/JP5102930B2/ja not_active Expired - Lifetime
- 2001-09-13 GB GB0308955A patent/GB2384709B/en not_active Expired - Fee Related
- 2001-09-13 US US10/345,000 patent/US20040018177A1/en not_active Abandoned
- 2001-09-13 AT AT01965468T patent/ATE465750T1/de active
- 2001-09-13 WO PCT/GB2001/004116 patent/WO2002024224A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001286109B2 (en) | 2006-12-14 |
| CA2422094C (en) | 2011-04-19 |
| CA2422094A1 (en) | 2002-03-28 |
| JP5102930B2 (ja) | 2012-12-19 |
| EP1320379B1 (de) | 2010-04-28 |
| GB0308955D0 (en) | 2003-05-28 |
| WO2002024224A3 (en) | 2002-06-13 |
| JP2004509149A (ja) | 2004-03-25 |
| GB2384709B (en) | 2005-05-04 |
| GB0023203D0 (en) | 2000-11-01 |
| EP1320379A2 (de) | 2003-06-25 |
| GB2384709A (en) | 2003-08-06 |
| WO2002024224A2 (en) | 2002-03-28 |
| DE60141969D1 (de) | 2010-06-10 |
| US20040018177A1 (en) | 2004-01-29 |
| EP1320379B8 (de) | 2010-06-02 |
| AU8610901A (en) | 2002-04-02 |
| ES2345604T3 (es) | 2010-09-28 |
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