ATE460163T1 - Arly und diaryl piperidinderivate verwendbar als mch-hemmer - Google Patents
Arly und diaryl piperidinderivate verwendbar als mch-hemmerInfo
- Publication number
- ATE460163T1 ATE460163T1 AT02731318T AT02731318T ATE460163T1 AT E460163 T1 ATE460163 T1 AT E460163T1 AT 02731318 T AT02731318 T AT 02731318T AT 02731318 T AT02731318 T AT 02731318T AT E460163 T1 ATE460163 T1 AT E460163T1
- Authority
- AT
- Austria
- Prior art keywords
- arly
- mch
- inhibitors
- piperidine derivatives
- derivatives usable
- Prior art date
Links
- -1 DIARYL PIPERIDINE DERIVATIVES Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28352301P | 2001-04-12 | 2001-04-12 | |
| PCT/US2002/011296 WO2002083134A1 (en) | 2001-04-12 | 2002-04-10 | Aryl and biaryl piperidines used as mch antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE460163T1 true ATE460163T1 (de) | 2010-03-15 |
Family
ID=23086443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02731318T ATE460163T1 (de) | 2001-04-12 | 2002-04-10 | Arly und diaryl piperidinderivate verwendbar als mch-hemmer |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6887889B2 (de) |
| EP (1) | EP1377293B1 (de) |
| JP (2) | JP4280073B2 (de) |
| AR (1) | AR035234A1 (de) |
| AT (1) | ATE460163T1 (de) |
| CA (1) | CA2443672C (de) |
| DE (1) | DE60235617D1 (de) |
| ES (1) | ES2340147T3 (de) |
| MX (1) | MXPA03009353A (de) |
| PE (1) | PE20021081A1 (de) |
| WO (1) | WO2002083134A1 (de) |
Families Citing this family (78)
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| US7084156B2 (en) | 2001-11-27 | 2006-08-01 | Merck & Co., Inc. | 2-Aminoquinoline compounds |
| EP1465635A4 (de) | 2002-01-10 | 2005-04-13 | Neurogen Corp | Melanin-konzentrierende hormonrezeptor-liganden: substituierte 2-(4-benzyl-piperazin-1-ylmethyl)- und 2-(4-benzyl-diazepan-1-ylmethyl)-1h-benzoimidazol-analoga |
| US6906075B2 (en) | 2002-01-10 | 2005-06-14 | Neurogen Corp. | Melanin concentrating hormone receptor ligands: substituted benzoimidazole analogues |
| JPWO2003091216A1 (ja) * | 2002-04-25 | 2005-09-02 | 住友製薬株式会社 | 新規ピペリジン誘導体 |
| JP2005538047A (ja) * | 2002-05-03 | 2005-12-15 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | ボンベシンアンタゴニスト |
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| US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
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| AU2003275257A1 (en) | 2002-09-26 | 2004-04-19 | Bristol-Myers Squibb Company | N-substituted heterocyclic amines as modulators of chemokine receptor activity |
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| KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
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| IL300610A (en) | 2020-08-18 | 2023-04-01 | Merck Sharp ַ& Dohme Llc | Bicycloheptane pyrrolidine compounds are orexin receptor agonists |
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| WO1999065494A1 (en) * | 1998-06-15 | 1999-12-23 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
| US6262066B1 (en) * | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
| ID29137A (id) * | 1998-07-27 | 2001-08-02 | Schering Corp | Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1 |
| US6303637B1 (en) | 1998-10-30 | 2001-10-16 | Merck & Co., Inc. | Heterocyclic potassium channel inhibitors |
| WO2000027845A1 (en) | 1998-11-10 | 2000-05-18 | Merck & Co., Inc. | Spiro-indolines as y5 receptor antagonists |
-
2002
- 2002-04-10 CA CA2443672A patent/CA2443672C/en not_active Expired - Fee Related
- 2002-04-10 MX MXPA03009353A patent/MXPA03009353A/es active IP Right Grant
- 2002-04-10 PE PE2002000298A patent/PE20021081A1/es not_active Application Discontinuation
- 2002-04-10 AR ARP020101318A patent/AR035234A1/es unknown
- 2002-04-10 ES ES02731318T patent/ES2340147T3/es not_active Expired - Lifetime
- 2002-04-10 AT AT02731318T patent/ATE460163T1/de not_active IP Right Cessation
- 2002-04-10 US US10/120,080 patent/US6887889B2/en not_active Expired - Fee Related
- 2002-04-10 JP JP2002580938A patent/JP4280073B2/ja not_active Expired - Fee Related
- 2002-04-10 EP EP02731318A patent/EP1377293B1/de not_active Expired - Lifetime
- 2002-04-10 DE DE60235617T patent/DE60235617D1/de not_active Expired - Lifetime
- 2002-04-10 WO PCT/US2002/011296 patent/WO2002083134A1/en active Application Filing
-
2009
- 2009-02-06 JP JP2009026802A patent/JP2009102430A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004526761A (ja) | 2004-09-02 |
| CA2443672A1 (en) | 2002-10-24 |
| CA2443672C (en) | 2011-03-29 |
| JP4280073B2 (ja) | 2009-06-17 |
| WO2002083134A1 (en) | 2002-10-24 |
| MXPA03009353A (es) | 2004-02-12 |
| US20030013720A1 (en) | 2003-01-16 |
| PE20021081A1 (es) | 2002-12-18 |
| JP2009102430A (ja) | 2009-05-14 |
| EP1377293A1 (de) | 2004-01-07 |
| EP1377293B1 (de) | 2010-03-10 |
| AR035234A1 (es) | 2004-05-05 |
| DE60235617D1 (de) | 2010-04-22 |
| ES2340147T3 (es) | 2010-05-31 |
| US6887889B2 (en) | 2005-05-03 |
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